Population genetical aspects of primary congenital glaucoma. I. Incidence, prevalence, gene frequency, and age of onset (original) (raw)

Summary

This paper presents some characteristics of the population genetics of primary congenital glaucoma in Slovakia. The overall in cidence in Slovakia is 1:10,500, while being 1:1,250 in the Gypsy subpopulation of Slovakia and 1:22,000 in the non-Gypsy population. For a special type of congenital primary glaucoma, transmitted by autosomal recessive inheritance in Gypsies the gene frequency may be estimated to reach 2.8%. Early onset of the disease enabling diagnosis soon after birth in 82% of patients may be considered another characteristic of this type of primary congenital glaucoma.

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Authors and Affiliations

1. Genetic Counseling Service, Department of Pediatrics, University of Bern, CH-3010, Bern, Switzerland
   A. Genčík
2. Department of Clinical Genetics, University Hospital, Bratislava, Czechoslovakia
   A. Genčíkova
3. Department of Anthropology, Comenins University, Bratislava, Czechoslovakia
   V. Ferák

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1. A. Genčík
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2. A. Genčíkova
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3. V. Ferák
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Genčík, A., Genčíkova, A. & Ferák, V. Population genetical aspects of primary congenital glaucoma. I. Incidence, prevalence, gene frequency, and age of onset.Hum Genet 61, 193–197 (1982). https://doi.org/10.1007/BF00296440

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• Received: 01 March 1982
• Published: 01 October 1982
• Issue Date: October 1982
• DOI: https://doi.org/10.1007/BF00296440

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