Selective localization of gelatinase A, an enzyme degrading β-amyloid protein, in white matter microglia and in Schwann cells (original) (raw)

Access this article

Log in via an institution

Subscribe and save

• Get 10 units per month
• Download Article/Chapter or eBook
• 1 Unit = 1 Article or 1 Chapter
• Cancel anytime Subscribe now

Buy Now

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

References

1. Backstrom JR, Miller CA, Tökés ZA (1992) Characterization of neutral proteinases from Alzheimer affected and control brain specimens: identification of calcium-dependent metalloproteinases from the hioppocampus. J Neurochem 58:983–992
   Google Scholar
2. Collier IE, Wilhelm SM, Eisen AZ, Marmer BL, Grant GA, Seltzer JL, Kronberger A, He C, Bauer EA, Goldberg GI (1988) H-ras oncogene-transformed human bronchial epithelial cells (TBE-1) secrete a single metalloproteinase capable for degrading basement membrane collagen. J Biol Chem 263: 6579–6587
   Google Scholar
3. Cras P, Kawai M, Siedlak S, Mulvihil P, Gambetti P, Lowery D, Gonzalez-Dewhitt P, Greengerg B, Perry G (1990) Neuronal and microglial involvement in β-amyloid protein deposition in Alzheimer's disease. Am J Pathol 137:241–246
   Google Scholar
4. DiStefano PS, Chelesa DM, Schick CM, McKelvy JF (1993) Involvement of a metalloprotease in low-affinity nerve growth factor receptor truncation: inhibition of truncation in vitro and in vivo. J Neurosci 13:2405–2414
   Google Scholar
5. Garbisa S, Ballin M, Daga-gordon D, Fastelli G, Naturale M, Negro A, Semenzato G, Liotta LA (1986) Transient expression of type IV collagenolytic metalloproteinase by human mononuclear phagocytes. J Biol Chem 261:2369–2375
   Google Scholar
6. Golde TT, Estus S, Usiak M, Youkin LH, Youkin SG (1990) Expression of β amyloid precursor mRNAs: recognition of a novel alternatively spliced form and quantitation in Alzheimer's disease using PCR. Neuron 4:253–267
   Google Scholar
7. Haas C, Hung AY, Selkoe DJ (1991) Processing of β-amyloid precursor protein in microglia and astrocytes favors an internal localization over constitutive secretion. J Neurosci 11:3783–3793
   Google Scholar
8. Khachaturian ZS (1985) Diagnosis of Alzheimer's disease. Arch Neurol 42:1097–1105
   Google Scholar
9. Mattiace LA, Davies P, Yen S-H, Dickson DW (1990) Microglia in cerebellar plaques in Alzheimer's disease. Acta Neuropathol 80:493–498
   Google Scholar
10. Mcdermott JR, Gibson AM (1991) The processing of Alzheimer A4/β-amyloid protein precursor: identification of a human brain metallopeptidase which cleaves-Lys-Leu-in a model peptide. Biochem Biophys Res Commun 179:1148–1154
    Google Scholar
11. McGeer PL, Akiyama H, Kawamata T, Yamada T, Walker DG, Ishii T (1992) Immunohistochemical localization of beta-amyloid precursor protein sequences in Alzheimer and normal brain tissue by light and electron microscopy. J Neurosci Res 31:428–442
    Google Scholar
12. Miyazaki K, Hasegawa M, Funahashi K, Umeda M (1993) A metalloproteinase inhibitor domain in Alzheimer amyloid protein precursor. Nature 362:839–841
    Google Scholar
13. Muir D, Manthorp M (1992) Stromelysin generates a fibronectin fragment that inhibits Schwann cell proliferation. J Cell Biol 116:177–185
    Google Scholar
14. Okada Y, Nagase H, Harris ED (1986) A metalloproteinase from human rheumatoid synovial fibroblasts that digests connective tissue matrix components. J Biol Chem 261:14245–14255
    Google Scholar
15. Ponte P, Gonzalez-DeWhitt P, Shilling J, Miller J, Hsu D, Greenberg B, Davis K, Wallace W, Lieberburg L, Fuller F, Cordell B (1988) A new A4 amyloid mRNA contains a domain homologous to serine proteinase inhibitors. Nature 331:525–527
    Google Scholar
16. Salo T, Liotta LA, Tryggvason K (1983) Purification and characterization of a murine basement membrane collagen-degrading enzyme secreted by metastatic tumor cells. J Biol Chem 258:3058–3063
    Google Scholar
17. Sapirstein VS, Durrie R, Berg MJ, Marks N (1994) Amyloid precursor protein is enriched in axolemma and periaxolemmalmyelin and associated clathrin-coated vesicles. J Neurosci Res 37:348–358
    Google Scholar
18. Seltzer JL, Weingarten H, Akers KT, Eschbach ML, Grant GA, Eisen AZ (1989) Cleavage specificity of type IV collagenase (gelatinase) from human skin. J Biol Chem 264:19583–19586
    Google Scholar
19. Tokuda T, Tanaka K, Kametani F, Ikeda S, Yanagisawa N (1994) Secretory form of β-amyloid precursor protein is much abundantly contained in the cerebral white matter in human brain. Neurosci Lett 175:33–36
    Google Scholar
20. Welgus HG, Fliszar CJ, Seltzer JL, Schmid TM, Jeffrey JJ (1990) Differential susceptibility of type X collagen to cleavage by two mammalian interstitial collagenases and 72-kDa type IV collagenase. J Biol Chem 265:13521–13527
    Google Scholar
21. Wisniewski HM, Weigel J (1993) Migration of perivascular cells into the neuropil and their involvement in β-amyloid plaque formation. Acta Neuropathol 85:586–595
    Google Scholar
22. Wisniewski HM, Weigel J, Wang KC, Kujawa M, Lach B (1989) Ultrastructural studies of the cells forming amyloid fibers in classical plaques. Can J Neurol Sci 16:535–542
    Google Scholar
23. Yamada T, Tsubouchi H, Daikuhara Y, Prat M, Comoglio PM, McGeer PL, McGeer EG (1994) Immunohistochemistry with antibodies to hepatocyte growth factor and its receptor protein (c-MET) in human brain tissues. Brain Res 637:308–312
    Google Scholar
24. Yamagata S, Ito Y, Tanaka R, Shimizu S (1988) Gelatinases of metastatic cell lines of murine colonic carcinoma as detected by substrate-gel electrophoresis. Biochem Biophys Res Commun 151:158–162
    Google Scholar
25. Yasumitsu H, Miyazaki K, Umenishi F, Koshikawa N, Umeda M (1992) Comparison of extracellular matrix-degrading activities between 64-kDa and 90-kDa gelatinases purified in inhibitor-free forms from human schwannoma cells. J Biochem 117:74–80
    Google Scholar
26. Zola H, Brooks D (1982) Techniques for the production and characterization of monoclonal hybridoma antibodies. In: Hurrel JGR (ed) Monoclonal hybridoma antibodies: techniques and applications. CRC Press, Boca Raton, pp 1–57
    Google Scholar
27. Zucker S, Turpeenniemi-Hujanen T, Ramamurthy N, Wieman J, Gorevic P, Liotta LA, Simon SR, Golub LM (1987) Purification and characterization of a connective tissue-degrading metalloproteinase from the cytosol of metastatic melanoma cells. Biochem J 245:429–437
    Google Scholar

Download references