Experimental model for liver metastasis formation using lewis lung tumor (original) (raw)

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Summary

A new experimental model is introduced for liver metastases using intrasplenically injected Lewis lung tumor cells. The appearance of liver metastases was studied in the presence and after the removal of primary tumor. The tumorous foci in the liver proved to be natural metastases and increased in number blocking the activity of the Kupffer cells by carragheenan. This model provides a useful tool to study different aspects of liver metastases.

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Authors and Affiliations

1. 1 st Institute of Pathology and Experimental Cancer Research, Semmelweis Medical University, Üllöi ut 26, H-1085, Budapest VIII, Hungary
   L. Kopper, T. Van Hanh & K. Lapis

Authors

1. L. Kopper
2. T. Van Hanh
3. K. Lapis

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Kopper, L., Van Hanh, T. & Lapis, K. Experimental model for liver metastasis formation using lewis lung tumor.J Cancer Res Clin Oncol 103, 31–38 (1982). https://doi.org/10.1007/BF00410303

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• Received: 12 March 1980
• Accepted: 12 September 1981
• Issue date: March 1982
• DOI: https://doi.org/10.1007/BF00410303

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