Insulin-like growth factor mediated stromal-epithelial interactions in human breast cancer (original) (raw)

References

  1. Van den Hooff A: Stromal involvement in malignant growth. Adv Canc Res 50: 159–195, 1991
    Google Scholar
  2. Cullen KJ, Lippman ME: Stromal-epithelial interactions in breast cancer. Cancer Treat Res 61: 413–431, 1992
    Google Scholar
  3. Basset P, Bellocq JP, Wolf C, Stoll I, Hutin P, Limacher JM, Podhajcer OL, Chenard MP, Rio MC, Chambon P: A novel metalloproteinase gene specifically expressed in stromal cells of breast carcinomas. Nature 348: 699–704, 1990
    Google Scholar
  4. Blundell TL, Humbel RE: Hormone families: pancreatic hormones and homologous grouwth factors. Nature 287: 781–787, 1980
    Google Scholar
  5. Humbel RE: Insulin-like growth factors I and II. Eur J Biochem 190: 445–462, 1990
    Google Scholar
  6. Cohick WS, Clemmons DR: The Insulin-like growth factors. Annu Rev Physiol 55: 131–153, 1993
    Google Scholar
  7. Voss JW, Rosenfeld MG: Anterior pituitary development: short tails from dwarf mice. Cell 70: 527–530, 1990
    Google Scholar
  8. Liu JP, Baker J, Perkins AS, Robertson EJ, Efstratiadis A: Mice carrying null mutations of the genes encoding insulin-like growth factor (igf-I) and type I IGF receptor (igf-Ir). Cell 75: 59–72, 1993
    Google Scholar
  9. De Chiara TM, Efstratiadis A: A growth deficiency phenotype in heterozygous mice carrying an insulin-like growth factor II gene disrupted by targeting. Nature 345: 78–80, 1990
    Google Scholar
  10. Baker J, Liu JP, Robertson EJ, Efstratiadis A: Role of insulin-like growth factors in embryonic and postnatal growth. Cell 75: 73–82, 1993
    Google Scholar
  11. Nissley SP, Rechler MM: Insulin-like growth factors: biosynthesis, receptors, and carrier proteins. Hormonal Proteins and Peptides 12: 127–203, 1986
    Google Scholar
  12. Unterman TG, Simmons RA, Glick RP, Ogata ES: Circulating levels of insulin, insulin-like growth factor-I (IGF-I), IGF-II, and IGF-binding proteins in the small for gestational age fetal rat. Endocrinology 132 (1): 327–336, 1993
    Google Scholar
  13. Gluckman PD, Ambler GR: What is the function of circulating insulin-like growth factor-2 in postnatal life? Mol Cell Endocrinol 92 (1): C1-C3, 1993
    Google Scholar
  14. Schofield PN, Tate VE: Regulation of human IGF-II transcription in fetal and adult tissues. Development 101: 793–803, 1987
    Google Scholar
  15. D'Ercole AJ, Stiles AD, Underwood LE: Tissue concentrations of somatomedin CL; Further evidence for multiple sites of synthesis and paracrine or autocrine mechanisms of action. Proc Natl Acad Sci USA 81: 935–939, 1984
    Google Scholar
  16. Reeve AE, Eccles MR, Wilkins RJ, Bell GI, Millow LJ: Expression of insulin-like growth factor II transcripts in Wilm's tumor. Nature 317: 258–260, 1985
    Google Scholar
  17. Nielsen FC, Haselbacher G, Christiansen J, Lake M, Gronborg M, Gammeltoft S: Biosynthesis of 10 kDa and 7.5 kDa insulin-like growth factor II in a human Rhabdomyosarcoma cell line. Mol Cell Endocrinol 93 (1): 87–95, 1993
    Google Scholar
  18. Drummond IA, Madden SL, Rohwer-Nutter P, Bell GI, Sukhatme VP, Rauscher FJ III: Repression of the insulin-like growth factor II gene by the Wilm's tumor suppressor WT-1. Science 257 (5070): 674–678, 1992
    Google Scholar
  19. Henry I, Bonaiti-Pellie C, Chehensse V, Beldjord C, Schwartz C, Utermann G, Junien C: Uniparental paternal disomy in a genetic cancer-predisposing syndrome. Nature 351: 665–667, 1991
    Google Scholar
  20. De Chiara TM, Robertson EJ, Efstradiadis A: Parental imprinting of the mouse insulin-like growth factor II gene. Cell 64: 849–859, 1991
    Google Scholar
  21. Giannoukakis N, Deal C, Paquette J, Goodyer CG, Polychronakos C: Parental genomic imprinting of the human IGF2 gene. Nat Genet 4 (1): 98–101, 1993
    Google Scholar
  22. Rainier S, Johnson LA, Dobry CJ, Ping AJ, Grundy PE, Feinberg AP: Relaxation of imprinted genes in human cancer. Nature 362 (6422): 747–749, 1993
    Google Scholar
  23. Ogawa O, Eccles MR, Szeto J, McNoe LA, Yun K, Maw MA, Smith PJ, Reeve AE: Relaxation of insulin-like growth factor II gene imprinting implicated in Wilm's tumour. Nature 362 (6422): 749–751, 1993
    Google Scholar
  24. Reeve JG, Brinkman A, Hughes S, Mitchell J, Schwander J, Bleehan NM: Expression of Insulin-like growth factor (IGF) and IGF-binding protein genes in human lung tumor cell lines. J Natl Cancer Institute 84: 628–634, 1992
    Google Scholar
  25. Su T-S, Liu W-Y, Han S-H, Jansen M, Yang-Fen TL, P'eng F-K, Chou C-K: Transcripts of the insulin-like growth factors I and II in human hepatoma. Cancer Res 49: 1773–1777, 1989
    Google Scholar
  26. Tricoli JV, Rall LB, Karakousis CP: Enhanced levels of insulin-like growth factor messenger RNA in human colon carcinomas and liposarcomas. Cancer Res 46: 6169–6173, 1986
    Google Scholar
  27. Yee D, Cullen KJ, Paik S, Perdue JF, Hampton B, Schwartz A, Lippman ME, Rosen N: Insulin-like growth factor II mRNA expression in human breast cancer. Cancer Res 48: 6691–6696, 1988
    Google Scholar
  28. Harbour JW, Lai SL, Whang-Pen J: Abnormalities in structure and expression of the human retinoblastoma gene in SCLC. Science 241: 353–357, 1988
    Google Scholar
  29. Varley JM, Armour J, Swallow JE: The retinoblastoma gene is frequently altered leading to loss of expression in primary breast cancers. Oncogene 4: 725–729, 1989
    Google Scholar
  30. Cullen KJ, Lippman ME: Estrogen regulation of protein synthesis and cell growth in human breast cancer. Vitam Horm 45: 127–172, 1989
    Google Scholar
  31. Yee D, Favoni RE, Lebovic GS, Lombana F, Powell DR, Reynolds CP, Rosen N: Insulin-like growth factor I expression of tumors of neuroectodermal origin with the t(11;22) chromosomal translocation. J Clin Invest 86: 1806–1814, 1990
    Google Scholar
  32. Sandberg AC, Enberg C, Lake M, Von Holst H, Sara VR: The expression of IGF-I and IGF-II genes in the human fetal and adult brain and glioma. Neuroscience Letts 93 (1): 114–119, 1990
    Google Scholar
  33. Yee D, Morales FR, Hamilton TC, Von Hoff DD: Expression of Insulin-like growth factor I, its binding proteins, and its receptor in ovarian cancer. Cancer Res 51: 5107–5112, 1991
    Google Scholar
  34. Nilsson O, Wangberg B, Theodorsson E, Skottner A, Ahlman H: Presence of IGF-I in human midgut carcinoid tumors- an antocrine regulator of carcinoid tumor growth? Int J Cancer 51 (2): 195–203, 1992
    Google Scholar
  35. Osborne CK, Coronado EB, Kitten LJ, Arteaga CI, Fuqua SA, Ramasharma K, Marshall M, Li CH: Insulin-like growth factor-II (IGF-II): a potential autocrine/paracrine growth factor for human breast cancer acting via the IGF-I receptor. Mol Endo 3: 1701–1709, 1989
    Google Scholar
  36. Cullen KJ, Yee D, Sly WS, Perdue J, Hampton B, Lippman ME, Rosen N: Insulin-like growth factor receptor expression and function in human breast cancer. Cancer Res 50 (1): 48–53, 1990
    Google Scholar
  37. Thorson T, Lahooti H, Rasmussen M, Aakvaag A: Oestrodiol treatment increases the sensitivity of MCF-7 cells for the growth stimulatory effect of IGF-I. J Steroid Biochem Mol Biol 41 (3-8): 537–540, 1992
    Google Scholar
  38. Stewart AJ, Johnson MD, May FEB, Westley BR: Role of insulin-like growth factors and type I insulin-like growth factor receptor in the estrogen stimulated proliferation of human breast cancer cells. J Biol Chem 265: 31172–31178, 1990
    Google Scholar
  39. Yee D, Paik S, Lebovic GS, Marcus RR, Favoni RE, Cullen KJ, Lippman ME, Rosen N: Analysis of insulin-like growth factor I gene expression in malignancy: evidence for a paracrine role in human breast cancer. Mol Endocrinol 3 (3): 509–517, 1989
    Google Scholar
  40. Paik S: Expression of IGF-I and IGF-II mRNA in breast tissue. Breast Cancer Res Treat 22 (1): 31–38, 1992
    Google Scholar
  41. Cullen KJ, Smith HS, Hill S, Rosen N, Lippman ME: Growth factor messenger RNA expression by human breast fibroblasts from benign and malignant lesions. Cancer Res 51 (18): 4978–4985, 1991
    Google Scholar
  42. Singer C, Smith HS, Lippman ME, Cullen KJ: IGF-I and IGF-II expression in fibroblasts derived from tumor, normal breast and skin of breast cancer patients. J Cell Biochem 16D: CC315, 1992
    Google Scholar
  43. Chiquet-Ehrismann R, Kalla P, Pearson CA: Participation of tenascin and transforming growth factor-β in reciprocal epithelial-mesenchymal interactions of MCF7 cells and fibroblasts. Cancer Res 49: 4322–4325, 1989
    Google Scholar
  44. Singer C, Cullen KJ: Manuscript in preparation
  45. Bronzert DA, Pantazis P, Antoniades HN, Kasid A, Davidson N, Dickson RB, Lippman ME: Synthesis and secretion of platelet derived growth factor by human breast cancer cell lines. Proc Natl Acad Sci USA 84: 5763–5767, 1987
    Google Scholar
  46. Clemmons DR: Multiple hormones stimulate the production of somatomedin by cultured human fibroblasts. J Clin Endocrinol Metab 58: 850–856, 1984
    Google Scholar
  47. Horgan K, Jones DL, Mansel RE: Mitogenicity of human fibroblasts_in vivo_ for human breast cancer cells. Br J Surg 74: 227–229, 1987
    Google Scholar
  48. Talts JF, Aufderheiden E, Sorokin L, Ocklind G, Mattsson R, Ekblom P: Induction of mouse tenascin by a human sarcomatoid Wilm's tumor cell line growing in nude mice. Int J Can 54: 868–874, 1993
    Google Scholar
  49. Cullen KJ, Lippman ME, Chow D, Hill S, Rosen N, Zwiebel JA: Insulin-like growth factor-II overexpression in MCF-7 cells induces phenotypic changes associated with malignant progression. Mol Endocrinol 6 (1): 91–100, 1992
    Google Scholar
  50. Daly RJ, Harris WH, Wang DY, Darbre PD: Autocrine production of insulin-like growth factor II using an inducible expression system results in reduced estrogen sensitivity of MCF-7 human breast cancer cells. Cell Growth Differen 2: 457–464, 1991
    Google Scholar
  51. Krywici RF, Yee D: The insulin-like growth factor family of ligands, receptors and binding proteins. Breast Cancer Res Treat 22: 7–19, 1992
    Google Scholar
  52. Siddle K: The insulin receptor and type I IGF receptor: Comparison of structure and function. Prog Growth Factor Res 4: 301–320, 1992
    Google Scholar
  53. Moxham CP, Jacobs S: Insulin/IGF-I receptor hybrids: A mechanism for increasing receptor diversity. J Cell Biochem 48: 136–140, 1992
    Google Scholar
  54. Baltensperger K, Kozma LM, Cherniack AD, Klarlund JK, Chawla A, Banerjee U, Czech MP: Binding of the Ras activator Son of Sevenless to insulin receptor substrate-I signalling complexes. Science 260: 1950–1952, 1993
    Google Scholar
  55. Skolnik EY, Batzer A, Li N, Lee C-H, Lowenstein E, Mohammadi M, Margolis B, Schlessinger J: The function of GRB2 in linking the insulin receptor to Ras signaling pathways. Science 260: 1953–1955, 1993
    Google Scholar
  56. Peyrat JPh, Bonneterre J: Type I IGF receptor in human breast diseases. Breast Cancer Res Treat 22: 59–67, 1992
    Google Scholar
  57. Berns EMJJ, Klijn JGM, Van Stavaren IL, Portengen H, Foekens JA: Sporadic amplification of the insulin-like growth factor I receptor in human breast tumors. Canc Res 52: 1036–1039, 1992
    Google Scholar
  58. Papa V, Biancamaria G, Clark GM, McGuire WL, Moore D, Fujita-Yamaguchi Y, Riccardo V, Goldfine ID, Pezzino V: Insulin-like growth factor receptors are overexpressed and predict a low risk in human breast cancer. Canc Res 53: 3736–3740, 1992
    Google Scholar
  59. Morgan DO, Edman JC, Standring DN, Fried VA, Smith MC, Roth RA, Rutter WJ: Insulin-like growth factor II receptor as a multifunctional binding protein. Nature 329: 301–307, 1987
    Google Scholar
  60. Vignon F, Rochefort H: Interactions of Pro-cathepsin D and IGF-II on the mannose-6-phosphate/IGF-II receptor. Breast Canc Res Treat 22: 47–57, 1992
    Google Scholar
  61. Dennis PA, Rifkin DB: Cellular activation of latent transforming growth factor β1 requires binding to the cation-in-dependent mannose-6-phosphate/insulin like growth factor II receptor. Proc Natl Acad Sci USA 88: 580–584, 1991
    Google Scholar
  62. Barlow DP, Stoger R, Hermann BG, Saito K, Schweifer N: The mouse insulin-like growth factor type 2 receptor is imprinted and closely linked to the Tme locus. Nature 349: 84–87, 1991
    Google Scholar
  63. Filson AJ, Louvi A, Efstratiadis A, Robertson EJ: Rescue of the T-associated maternal effect in mice carrying null mutations in_Igf-2_ and_Igf-2r_, two reciprocally imprinted genes. Development 118: 731–736, 1993
    Google Scholar
  64. Nishimoto I, Murayama Y, Katada T, Ui M, Ogata E: Possible direct linkage of insulin-like growth factor-II receptor with guanine nucleotide-binding proteins. J Biol Chem 264 (24): 14029–14038, 1989
    Google Scholar
  65. Zhoa Y, Escot C, Maudelonde T, Puech C, Rouanet P, Rochefort H: Correlation between Mannose-6-phosphate/IGF-II receptor and Cathepsin D RNA levels by_in situ_ hybridization in benign and malignant mammary tumors. Canc Res 53: 2901–2905, 1993
    Google Scholar
  66. Jirtle RL, Haag JD, Ariazi EA, Gould MN: Increased Mannose 6-phosphate/insulin-like growth factor II receptor and transforming growth factor β1 levels during monoterpeneinduced regression of mammary tumors. Canc Res 53: 3849–3852, 1993
    Google Scholar
  67. Pietrzkowski Z, Lammers R, Carpenter G, Soderquist AM, Limardo M, Phillips PD, Ullrich A, Baserga R: Constitutive expression of insulin-like growth factor 1 and insulin-like growth factor 1 receptor abrogates all requirements for exogenous growth factors. Cell Growth Diff 3: 199–205, 1992
    Google Scholar
  68. Baserga R: IGF-I receptor as the restriction point of the cell cycle. Ann NY Acad Sci 663: 154–157, 1992
    Google Scholar
  69. Milazzo G, Yip CC, Maddux BA, Vigneri R, Goldfine ID: High affinity Insulin biding to an atypical insulin-like growth factor-I receptor in human breast cancer cells. J Clin Invest 89: 899–908, 1992
    Google Scholar
  70. Sakana K, Enjoh T, Numata F, Fujiwara H, Marumoto Y, Higashihash N, Sata Y, Perdue J, Fujita-Yamaguchi Y: The design, expression, and characterisation of human Insulin-like growth factor II (IGF-II) mutants specific for either the IGF-II/cation-independent mannose-6-phosphate receptor or IGF-I receptor. J Biol Chem 266: 20626–20635, 1991
    Google Scholar

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