Coexistence of cytokeratin, vimentin and neurofilament protein in human choroid plexus (original) (raw)

Summary

The expression of intermediate filament proteins in human brain ependyma and choroid plexus epithelium has been studied by immunohistochemistry using a panel of monoclonal antibodies directed against all five classes of intermediate filaments. Ependymal cells express GFAP and vimentin filaments, whereas plexus epithelium simultaneously contains neurofilaments, cytokeratins and vimentin, a phenomenon not previously observed in normal cells in vivo. By means of specific antibodies we were able to establish that cytokeratins 8 and 18 but not 19 are present in plexus epithelium.

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Authors and Affiliations

1. Institute of Pathology, District Hospital, Görlitz
   Michael Kasper, Roland Goertchen & Peter Stosiek
2. Division of Neuropathology, Institute of Pathology, Case Western, Reserve University, Cleveland, Ohio, USA
   George Perry
3. Department of Experimental and Clinical Immunology, Central Institute of Molecular Biology, Academy of Sciences of the GDR, Berlin-Buch, GDR
   Uwe Karsten

Authors

1. Michael Kasper
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2. Roland Goertchen
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3. Peter Stosiek
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4. George Perry
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5. Uwe Karsten
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Kasper, M., Goertchen, R., Stosiek, P. et al. Coexistence of cytokeratin, vimentin and neurofilament protein in human choroid plexus.Vichows Archiv A Pathol Anat 410, 173–177 (1987). https://doi.org/10.1007/BF00710822

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• Accepted: 31 July 1986
• Issue Date: May 1987
• DOI: https://doi.org/10.1007/BF00710822

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