Anti-OKT3 response following prophylactic treatment in paediatric kidney transplant recipients (original) (raw)

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References

1. Norman DJ, Shield CF, Barry JM (1987) Therapeutic use of OKT3 monoclonal antibody for acute renal allograft rejection. Nephron 46: 41–47
   PubMed Google Scholar
2. Cosimi AB, Burton RC, Colvin RB, Goldstein G, Delmonico FL, Laquaglia MP, Tolkoff-Rubin N, Rubin RH, Herrin JT, Russel PS (1981) Treatment of acute renal allograft rejection with OKT3 monoclonal antibody. Transplantation 32: 535–539
   PubMed Google Scholar
3. Costanzo-Nordin MR, Silver MA, O'Connell JB (1987) Successful reversal of acute cardiac allograft rejection with OKT3 monoclonal antibody. Circulation 76: 71–80
   Google Scholar
4. Fung JJ, Markus BH, Gordon RD, Esquivel CO, Makowka L, Tzakis AG, Starzl TE (1987) Impact of Orthoclone OKT3 on liver transplantation. Transplant Proc 19: 37–44
   Google Scholar
5. Oruto Multicenter Transplant Study Group (1985) A randomized clinical trial of OKT3 monoclonal antibody for acute rejection of cadaveric renal transplants. N Engl J Med 313: 337–342
   Google Scholar
6. Kahana L, Baxter J (1987) OKT3 rescue in refractory renal rejection. Nephron 46: 34–40
   Google Scholar
7. Colona JO, Goldstein LI, Brems JJ, Vargas JH, Brill JE, Berquist W, Hiatt JR, Busuttil RW (1987) A prospective study on the use of monoclonal anti-T3-cell antibody (OKT3) to treat steroid-resistant liver transplant rejection. Arch Surg 122: 1120–1123
   PubMed Google Scholar
8. Ackermann JR (1988) Prophylactic use of OKT3 in renal transplantation: part of a prospective randomized multicenter trial. Transplant Proc 20: 242–244
   PubMed Google Scholar
9. Kreis H, Chkoff N, Chatenoud L (1989) A randomized trial comparing the efficacy of OKT3 used to prevent or to treat rejection. Transplant Proc 21: 3
   Google Scholar
10. Norman DJ, Shield CF, Barry J (1988) Early use of OKT3 monoclonal antibody in renal transplantation to prevent rejection. Am J Kidney Dis 11: 107–110
    PubMed Google Scholar
11. Vigeral P, Chkoff N, Chatenoud L, Campos H, Lacombe M, Droz D, Goldstein G, Bach JF, Kreis H (1986) Prophylactic use of OKT3 monoclonal antibody in cadaver kidney recipients. Utilization of OKT3 as the sole immunosuppressive agent. Transplantation 41: 730–733
    PubMed Google Scholar
12. Norman DJ, Leone MR (1991) The role of OKT3 in clinical transplantation. Pediatr Nephrol 5: 130–136
    PubMed Google Scholar
13. Chatenoud L, Baudrihaye MF, Chkoff N, Kreis H, Bach JF (1983) Immunologic follow-up of renal allograft recipients treated prophylactically by OKT3 alone. Transplant Proc 15: 643–645
    Google Scholar
14. Schroeder TJ, Frist MR, Mansour ME, Hurtubisse PE, Hariharan S, Ryckman FC, Munda R, Melvin DB, Penn I, Ballistreri WF, Alexander JW (1990) Antimurine antibody formation following OKT3 therapy. Transplantation 49: 48–51
    PubMed Google Scholar
15. Mayes JT, Thistlethwaite JR, Stuart JJ, Buckingham MR, Stuart FP (1988) Reexposure to OKT3 in renal allograft recipients. Transplantation 45: 349–353
    PubMed Google Scholar
16. Norman DJ, Shield CF, Henell KR, Kimball J, Barry JM, Bennett WM, Leone M (1988) Effectiveness of a second course of OKT3 monoclonal anti-T cell antibody for treatment of renal allograft rejection. Transplantation 46: 523–529
    PubMed Google Scholar
17. Hricik DE, Mayes JT, Shulak JA (1990) Inhibition of anti-OKT3 antibody generation by ciclosporine: results of a prospective randomized trial. Transplantation 50: 237–240
    PubMed Google Scholar
18. Jaffers GJ, Fuller T, Cosimi AB, Russell PS, Win HJ, Colvin RB (1986) Monoclonal antibody therapy: antiidiotypic and non-antiidiotypic antibodies to OKT3 arising despite intense immunosuppression. Transplantation 41: 572–578
    PubMed Google Scholar
19. Leone MR, Barry JM, Alexander SR, Melvin T, Striegel J, Henell KR, Kimball J, Funnell MB, Goldstein G, Norman DJ (1990) Monoclonal antibody OKT3 therpay in pediatric kidney transplant recipients. J Pediatr 116: S86-S91
    PubMed Google Scholar
20. Chatenoud L, Baudrihaye MF, Chkoff N, Kreis H, Goldstein G, Batch JF (1986) Restriction of the human in vivo immune response against the mouse monoclonal antibody OKT3 J Immunol 137: 830–838
    PubMed Google Scholar
21. Niaudet P, Murcia I, Jean G, Broyer M (1990) Essai comparatif de l'OKT3 et du sérum antilymphocytaire dans le traitement préventif du rejet après transplantation rénale chez l'enfant. Ann Pediatr (Paris) 37: 83–85
    Google Scholar
22. Schroeder T, Superina R, Ettinger R (1992) Monoclonal antibody therapy in pediatric transplantation. Transplant Proc 24: S1-S10
    Google Scholar
23. Legendre C, Kreis H, Bach JF, Chatenoud L (1992) Prediction of successful allograft rejection retreatment with OKT3. Transplantation 53: 87–90
    PubMed Google Scholar

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