Acute renal failure after exercise in a child with renal hypouricaemia (original) (raw)

Abstract

We describe a 12-year-old boy with renal hypouricaemia who presented with acute renal failure after a 6-h sports training session. Back and loin pain were noted at presentation. Although serum creatinine and blood urea nitrogen were elevated, the serum uric acid concentration was normal (2.6 mg/dl). This decreased to 0.3 mg/dl after recovery. The pyrazinamide and probenecid tests revealed that the cause of renal hypouricaemia in this patient was totally defective uric acid reabsorption. Acute renal failure after exercise is a rare but serious complication in paediatric patients with renal hypouricaemia.

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Authors and Affiliations

  1. Department of Paediatrics, Faculty of Medicine, The University of Tokyo, Mejirodai Campus, 3-28-6 Mejirodai, 112, Bunkyo-ku, Tokyo, Japan
    Takashi Igarashi, Takashi Sekine, Hiroko Sugimura & Hiroshi Hayakawa
  2. Department of Paediatrics, Kikkoman General Hospital, Noda-city, Chiba, Japan
    Takashi Arayama

Authors

  1. Takashi Igarashi
  2. Takashi Sekine
  3. Hiroko Sugimura
  4. Hiroshi Hayakawa
  5. Takashi Arayama

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Igarashi, T., Sekine, T., Sugimura, H. et al. Acute renal failure after exercise in a child with renal hypouricaemia.Pediatr Nephrol 7, 292–293 (1993). https://doi.org/10.1007/BF00853226

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