Subretinal neovascular membranes associated with chronic membranoproliferative glomerulonephritis type II (original) (raw)

Abstract

Subretinal neovascular membranes were observed in three patients with chronic membranoproliferative glomerulonephritis type II (dense deposit disease). The first signs of glomerulonephritis occurred at respective ages of 13, 10 and 10 years; subretinal neovascular membranes were noted at respective ages of 25, 32 and 32 years. All patients had bilateral, widespread retinal pigment epithelial abnormalities. Our findings indicate that subretinal neovascularization is a complication of dense deposit disease. In one patient, the early recognition and laser treatment of an extrafoveal subretinal neovascular membrane prevented further loss of vision.

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Authors and Affiliations

  1. Department of Ophthalmology, Katholieke Universiteit, Leuven, Belgium
    Anita Leys, Brigitte Michielsen & Luc Missotten
  2. Department of Nephrology, Katholieke Universiteit, Leuven, Belgium
    Yves Vanrenterghem
  3. Department of Pathology, Katholieke Universiteit, Leuven, Belgium
    Baudewijn Van Damme
  4. Department of Ophthalmology, Rijksuniversiteit, Gent, Belgium
    Monique Leys

Authors

  1. Anita Leys
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  2. Brigitte Michielsen
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  3. Monique Leys
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  4. Yves Vanrenterghem
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  5. Luc Missotten
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  6. Baudewijn Van Damme
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Leys, A., Michielsen, B., Leys, M. et al. Subretinal neovascular membranes associated with chronic membranoproliferative glomerulonephritis type II.Graefe's Arch Clin Exp Ophthalmol 228, 499–504 (1990). https://doi.org/10.1007/BF00918479

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