Echinostoma population regulation in experimental rodent definitive hosts (original) (raw)

Abstract

Echinostoma population regulation in the experimental rodent host is governed by the capacity of the latter to express an effective regulatory response. Parasite establishment, survival and fecundity are affected by host-related factors such as species, strain and age and by parasite-related factors such as species, age and the burden of infection. The genetic heterogeneity in the regulatory response to infection is marked. The most intensively studied host/echinostome combinations comprise_E. caproni_ and_E. trivolvis_ in the mouse host, for which a range of interesting host-parasite relationships has been demonstrated, including concomitant immunity with rapid expulsion of superimposed infections, a long-lasting resistance to secondary infection, a negatively dose-dependent pattern of expulsion of primary infections, a positively dose-dependent reproductive potential, an infective-dose independency of primary worm establishment, and a range of heterologous antagonistic and synergistic interactions in concurrent infections with related and unrelated parasite species. The_Echinostoma_/rodent model is highly suitable for studying aspects of parasite population regulation in intestinal trematode infections.

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References

• Barus V, Moravec F, Rysavy B (1974) Antagonistic interaction between_Echinostoma revolutum_ and_Echinoparyphium recurvatum_ (Trematoda) in the definitive host. Folia Parasitol (Prague) 21:155–159
  Google Scholar
• Beaver PC (1937) Experimental studies on_Echinostoma revolutum_ (Froelich), a fluke from birds and mammals. Ill Biol Monogr 15:1–96
  Google Scholar
• Bindseil E, Christensen NØ (1984) Thymus-independent crypt hyperplasia and villous atrophy in the small intestine of mice infected with the trematode_Echinostoma revolutum_. Parasitology 88:431–438
  PubMed Google Scholar
• Christensen NØ (1980)Echinostoma revolutum: labeling of miracidia with radioselenium in vivo and assay for host finding. Exp Parasitol 50:67–73
  PubMed Google Scholar
• Christensen NØ, Frandsen F, Roushdy MZ (1980) The influence of environmental conditions and parasite-intermediate host-related factors on the transmission of_Echinostoma liet_. Z Parasitenkd 63:47–63
  PubMed Google Scholar
• Christensen NØ, Nydal R, Frandsen F, Nasen P (1981a) Homologous immunotolerance and decreased resistance to_Schistosoma mansoni_ in_Echinostoma revolutum_-infected mice. J Parasitol 67:164–166
  PubMed Google Scholar
• Christensen NØ, Nydal R, Frandsen F, Sirag SB, Nansen P (1981b) Further studies on resistance to_Fasciola hepatica_ and_Echinostoma revolutum_ in mice infected with_Schistosoma_ sp. Z Parasitenkd 65:293–298
  PubMed Google Scholar
• Christensen NØ, Fagbemi BO, Nansen P (1984)Trypanosoma brucei_-induced blockage of expulsion of_Echistosoma revolutum and of homologous_E. revolutum_ resistance in mice. J Parasitol 70:558–561
  PubMed Google Scholar
• Christensen NØ, Knudsen J, Fagbemi BO, Nansen P (1985) Impairment of primary expulsion of_Echinostoma revolutum_ in mice concurrently infected with_Schistosoma mansoni_. J Helminthol 59:333–335
  PubMed Google Scholar
• Christensen NØ, Knudsen J, Andreassen J (1986)Echinostoma revolutum: resistance to secondary and superimposed infections in mice. Exp Parasitol 61:311–318
  PubMed Google Scholar
• Christensen NØ, Furu P, Kurtzhals J, Odaibo A (1988) Heterologous synergistic interactions in concurrent experimental infection in the mouse with_Schistosoma mansoni, Echinostoma revolutum, Plasmodium yoelii, Babesia microti_ and_Trypanosoma brucei_. Parasitol Res 74:544–551
  PubMed Google Scholar
• Cross JH, Basaca-Sevilla V (1986) Studies on_Echinostoma ilocanum_ in the Phillippines. Southeast Asian J Trop Med Pub Health 17:23–27
  Google Scholar
• Franco J, Huffman JE, Fried B (1986) Infectivity, growth, and development of_Echinostoma revolutum_ (Digenea: Echinostomatidae) in the golden hamster,Mesocricetums auratus. J Parasitol 72:142–147
  PubMed Google Scholar
• Fried B (1985) Maintenance of_Echinostoma revolutum_ (Trematoda) in the laboratory. Proc P Acad Sci 59:27–28
  Google Scholar
• Fried B, Huffman JE, Franco J (1988) Single- and five-worm infections of_Echinostoma revolutum_ (Trematoda) in the golden hamster. Int J Parasitol 18:179–181
  PubMed Google Scholar
• Hosier DW, Fried B (1986) Infectivity, growth, and distribution of_Echinostoma revolutum_ in Swiss Webster and ICR mice. Proc Helminthol Soc Wash 53:173–176
  Google Scholar
• Hosier DW, Fried B, Szewczak JP (1988) Homologous and heterologous resistance of_Echinostoma revolutum_ and_E. liei_ in ICR mice. J Parasitol 74:89–92
  PubMed Google Scholar
• Hsu KC, Lie KJ, Basch PF (1968) The life history of_Echinostoma rodriguesi_ sp. n. (Trematoda: Echinostomatidae). J Parasitol 54:333–339
  PubMed Google Scholar
• Huffman JE, Michos C, Fried B (1986) Clinical and pathological effects of_Echinostoma revolutum_ (Digenea: Echinostomatidae) in the golden hamster,Mesocricetus auratus. Parasitology 93:505–515
  PubMed Google Scholar
• Jourdane J, Kulo SD (1981) Etude expérimentale du cycle biologique de_Echinostoma togoensis_ n. sp., parasite l'état larvaire de_Biomphalaria pfeifferi_ au Togo. Ann Parasitol Hum Comp 56:477–488
  PubMed Google Scholar
• Kanev I (1985) On the morphology, biology, ecology and taxonomy of_E. revolutum_ group (Trematoda: Echinostomatidae:Echinostoma). Doctoral Dissertation, University of Sofia, Bulgaria
  Google Scholar
• Lie KJ (1963) The life history of_Echinostoma malayanum_ Leiper, 1911. Trop Geogr Med 15:17–24
  PubMed Google Scholar
• Lie KJ (1964) Studies on Echinostomatidae (Trematoda) in Malaya: VII. The life history of_Echinostoma lindoense_ Sandground and Bonne, 1940. Trop Georg Med 16:72–81
  Google Scholar
• Lie KJ, Basch PF (1967) The life history of_Echinostoma paraensei_ sp. n. (Trematoda: Echinostamatidae). J Parasitol 53:1192–1199
  PubMed Google Scholar
• Lie KJ, Virik HK (1963) Human infection with_Echinostoma malayanum_ Leiper, 1911 (Trematoda: Echinostomatidae). J Trop Med Hyg 66:77–82
  PubMed Google Scholar
• Mohandas A, Nadakal AM (1978) In vivo development of_Echinostoma malayanum_ Leiper 1911 with notes on effects of population density, chemical composition and pathogenicity and in vitro excystment of the metacercaria (Trematoda: Echinostomatidae). Z Parasitenkd 55:139–151
  PubMed Google Scholar
• Odaibo AB, Christensen NØ, Ukoli FMA (1988) Establishment, survival, and fecundity in_Echinostoma caproni_ infections in NMRI mice. Proc Helminthol Soc Wash 55:265–269
  Google Scholar
• Sandground JH, Bonne C (1940)Echinostoma lindoensis n. sp., a new parasite on man in the Celebes with an account of its life history and epidemiology. Am J Trop Med 20:511–535
  Google Scholar
• Senger CM (1954) Notes on the growth, development and survival of two echinostome trematodes. Exp Parasitol 6:491–496
  Google Scholar
• Simonsen PE, Andersen BJ (1986)Echinostoma revolutum in mice: dynamics of the antibody attack to the surface of an intestinal trematode. Int J Parasitol 16:475–482
  PubMed Google Scholar
• Sirag SB, Christensen NØ, Frandsen F, Monrad J, Nansen P (1980) Homologous and heterologous resistance in_Echinostoma revolutum_ infections in mice. Parasitology 80:479–486
  PubMed Google Scholar
• Thorndyke M, Whitfield PJ (1987) Vasoactive intestinal polypeptide immunoreactive tegumental cells in the digenean_Echinostoma liei_: possible role in host-parasite interactions. Gen Comp Endocrinol 68:202–207
  PubMed Google Scholar

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Authors and Affiliations

1. Danish Bilharziasis Laboratory, Jaegersborg Alle 1D, DK-2920, Charlottenlund, Denmark
   Niels Ø. Christensen, Alexander B. Odaibo & Paul E. Simonsen

Authors

1. Niels Ø. Christensen
2. Alexander B. Odaibo
3. Paul E. Simonsen

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Christensen, N.Ø., Odaibo, A.B. & Simonsen, P.E. Echinostoma population regulation in experimental rodent definitive hosts.Parasitol Res 75, 83–87 (1988). https://doi.org/10.1007/BF00932705

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• Accepted: 28 August 1988
• Issue date: February 1988
• DOI: https://doi.org/10.1007/BF00932705

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