Receptor-mediated pharmacodynamics of prednisolone in the rat (original) (raw)

• G. Levy. Kinetics of pharmacologic effects.Clin. Pharmacol. Ther. 7:362–372 (1966).
  CAS PubMed Google Scholar
• E. J. Ariens. Drug levels in the target tissue and effect.Clin. Pharmacol. Ther. 16:155–175 (1974).
  CAS PubMed Google Scholar
• N. H. G. Holford and L. B. Sheiner. Pharmacokinetic and pharmacodynamic modeling_in vivo_.CRC Crit. Rev. Bioeng. 5:273–322 (1981).
  CAS Google Scholar
• B. Oosterhuis. R. J. M. Ten Berge, H. P. Sauerwein, E. Endert, P. T. A. Schellekens, and C. J. Van Boxtel. Pharmacokinetic-pharmacodynamic modeling of prednisolone induced lymphocytopenia in man.J. Pharmacol. Exp. Ther. 229:539–545 (1984).
  CAS PubMed Google Scholar
• L. K. Paalzow. Integrated pharmacokinetic-pharmacodynamic modeling of drugs acting on the CNS.Metab. Rev. 15:383–400 (1984).
  Article Google Scholar
• M. L. Jack, W. A. Colburn, N. M. Spirt, G. Bautz, M. Zanko, W. D. Horst, and R. A. O'Brien. A pharmacokinetic/pharmacodynamic/receptor binding model to predict the onset and duration of pharmacological activity of the benzodiazepines.Prog. Neuropsychopharmacol. Biol. Psychiat. 7:629–635 (1983).
  Article CAS Google Scholar
• E. V. Jenson and H. I. Jacobson. Basic guides to the mechanism of estrogen action.Recent Prog. Horm. Res. 18:387–414 (1962).
  Google Scholar
• J. D. Baxter and J. W. Funder. Hormone receptors.N. Engl. J. Med. 301:1149–1161 (1979).
  Article CAS PubMed Google Scholar
• A. Munck and K. Leung. In J. R. Pasqualini (ed.),Glucocorticoid Receptors and Mechanism of Action of Steroid Hormones, Marcel Dekker, New York, 1977, pp. 311–397.
  Google Scholar
• M. Izawa, A. Yoshida, and S. Ichii. Dynamics of glucocorticoid receptor and induction of tyrosine aminotransferase in rat liver.Endocrinol. Japon. 29:209–218 (1982).
  Article CAS Google Scholar
• T. J. Schmidt and G. Litwack. Activation of the glucocorticoid-receptor complex.Physiol. Rev. 62:1131–1192 (1982).
  CAS PubMed Google Scholar
• G. G. Rousseau. Control of gene expression by glucocorticoid hormones.Biol. Chem. J. 225:1–12 (1984).
  Google Scholar
• G. J. Blackwell, R. Carnuccio, M. DiRosa, R. J. Flower, L. Parente, and P. Pessico. Macrocortin: A polypeptide causing anti-phospholipase effect of glucocorticoids.Nature 287:147–149 (1980).
  Article CAS PubMed Google Scholar
• P. L. Ballard, J. D. Baxter, S. J. Higgins, G. G. Rousseau, and G. M. Tomkins. General presence of glucocorticoid receptors in mammalian tissues.Endocrinology 94:998–1002 (1974).
  Article CAS PubMed Google Scholar
• A. M. P. Saaverdra-Delgrado, K. P. Mathews, P. M. Pan, D. R. Kay, and M. L. Mulenberg. Dose response studies of the suppression of whole blood histamine and basophil counts of prednisone.J. Allergy Clin. Immunol. 66:464–471 (1980).
  Article Google Scholar
• R. Ellul-Micallef and F. F. Fenech. Intravenous prednisolone in chronic bronchial asthma.Thorax 30:312–315 (1975).
  Article CAS PubMed Central PubMed Google Scholar
• H. Kitagawa, T. Mohri, and M. Kitagawa. Comparative studies on anti-inflammatory effect and biological fates of 21-phosphates and -sulfates of dexamethasone and prednisolone,Arzneim. Forsch. 22:402–410 (1972).
  CAS Google Scholar
• M. Kalimi, M. Beato, and P. Feigelson. Interaction of glucocorticoids with rat liver nuclei. I. Role of the cytosol proteins.Biochemistry 12:3365–3371 (1973).
  Article CAS PubMed Google Scholar
• C. R. Wira and A. Munck. Glucocorticoid-receptor complexes in rat thymus cells.J. Biol. Chem. 249:5328–5336 (1974).
  CAS PubMed Google Scholar
• F. Payvar, O. Wrange, J. Carlstedt-Duke, S. Okret, J.-A. Gustafsson, and K. R. Yamamoto. Purified glucocorticoid receptors binding selectively_in vitro_ to a cloned DNA fragment whose transcription is regulated by glucocorticoids_in vivo_.Proc. Natl. Acad. Sci. USA 78:6628–6632 (1981).
  Article CAS PubMed Central PubMed Google Scholar
• M. Pfahl. Specific binding of the glucocorticoid-receptor complex to the mouse mammary tumor proviral promotor region.Cell 31:475–482 (1982).
  Article CAS PubMed Google Scholar
• B. M. Raaka and H. H. Samuels. The glucocorticoid receptor in GH1 cells.J. Biol. Chem. 258:417–425 (1983).
  CAS PubMed Google Scholar
• S. Miyabe and R. W. Harrison.In vivo activation and nuclear binding of the ALT-20 mouse pituitary tumor cell glucocorticoid receptor.Endocrinology 112:2174–2180 (1983).
  Article CAS PubMed Google Scholar
• J. M. Nickol, K.-L. Lee, and F. T. Kenney. Changes in hepatic levels of tyrosine aminotransferase messenger RNA during induction by hydrocortisone.J. Biol. Chem. 253:4009–4015 (1978).
  CAS PubMed Google Scholar
• D. Granner, P. Olson, S. Seifert, C. Block, M. Diesterhaft, J. Hargrove, and T. Noguchi. Regulation of tyrosine aminotransferase mRNA in HTC cells.Ann. N. Y. Acad. Sci. 349:183–194 (1980).
  Article CAS PubMed Google Scholar
• J. Q. Rose and W. J. Jusko. Corticosteroid analysis in biological fluids by high-performance liquid chromatography.J. Chromatogr. 162:273–280 (1979).
  Article CAS PubMed Google Scholar
• N. Khalafallah and W. J. Jusko. Tissue distribution of prednisolone in the rabbit.J. Pharmacol. Exp. Ther. 229:719–725 (1984).
  CAS PubMed Google Scholar
• F. D. Boudinot and W. J. Jusko. Fluid shifts and other factors affecting plasma protein binding of prednisolone by equilibrium dialysis.J. Pharm. Sci. 73:774–780 (1984).
  Article CAS PubMed Google Scholar
• R. L. Priore and H. E. Rosenthal. A statistical method for the estimation of binding parameters in a complex system.Anal. Biochem. 70:231–240 (1976).
  Article CAS PubMed Google Scholar
• Packard Instrument Co., Instrument Manual 2136, Downers Grove, Illinois (1977).
  Google Scholar
• N. Lui, R. R. Almon, and W. J. Jusko. Comparison of filtration and equilibrium dialysis methods for3H-imipramine binding to human platelets.Anal. Biochem. 139:42–57 (1984).
  Article CAS PubMed Google Scholar
• C. M. Metzler, G. K. Elfring, and A. J. McEwen. A package of computer programs for pharmacokinetic modeling.Biometrics 30:562–563 (1974).
  Article Google Scholar
• T. I. Diamondstone. Assay of tyrosine transaminase activity by conversion of_p_-hyroxyphenylpyruvate to_p_-hydroxybenzaldehyde.Anal. Biochem. 16:395–401 (1966).
  Article CAS Google Scholar
• O. M. Lowry, N. J. Rosebrough, A. L. Farr, and R. J. Randal. Protein measurement with the folin phenol reagent.J. Biol. Chem. 193:265–272 (1951).
  CAS PubMed Google Scholar
• F. D. Boudinot and W. J. Jusko. Dose dependent pharmacokinetics of prednisolone in normal and adrenalectomized rats.J. Pharmacokin. Biopharm. 14:453–467 (1986).
  Article CAS Google Scholar
• P. G. W. Plageman and J. Erbe. Glucocorticoids-uptake by simple diffusion by cultured Reuber and Novikoff rat hepatoma cells.Biochem. Pharmacol. 25:1489–1494 (1976).
  Article Google Scholar
• W. M. Pardridge and L. J. Mietus. Transport of protein-bound steroid hormones into liver_in vivo_.Am. J. Physiol. 237:E367-E372 (1979).
  CAS PubMed Google Scholar
• S. R. Gross, L. Aronow, and W. B. Pratt. The active transport of cortisol of mouse fibroblasts growing_in vitro_.J. Cell. Biol. 44:103–114 (1970).
  Article CAS PubMed Central PubMed Google Scholar
• M. L. Rao, G. S. Rao, M. Holler, H. Breuer, P. J. Schattenberg, and W. D. Stein. Uptake of cortisol by isolated rat liver cells. A phenomenon indicative of carrier-mediation and simple diffusion.J. Physiol. Chem. 357:573–584 (1976).
  Article CAS Google Scholar
• J. F. Hackney, S. R. Gross, L. Aronow, and W. B. Pratt. Specific glucocorticoid-binding macromolecules from mouse fibroblasts growing_in vitro_.Mol. Pharmacol. 6:500–512 (1970).
  CAS PubMed Google Scholar
• N. Khalafallah and W. J. Jusko. Determination and prediction of tissue binding of prednisolone in the rabbit.J. Pharm. Sci. 73:362–366 (1984).
  Article CAS PubMed Google Scholar
• M. Mayer, N. Kaiser, R. J. Millholland, and F. Rosen. Cortisol binding in rat skeletal muscle.J. Biol. Chem. 250:1207–1210 (1975).
  CAS PubMed Google Scholar
• W. R. Slaunwhite, G. M. Lockie, N. Back, and A. A. Sandberg. Inactivity_in vivo_ of transcortin bound cortisol.Science 135:1062–1063 (1962).
  Article CAS PubMed Google Scholar
• A. Kawai and F. E. Yates. Interference with feedback inhibition of adrenocorticotropin release by protein binding of corticosterone.Endocrinology 79:1040–1046 (1965).
  Article Google Scholar
• B. Koch, B. Lutz, G. Schmitt, and C. Mailhe. Influence of transcortin on degradation and tissue uptake of corticosterone in the infant rat.Horm. Metab. Res. 2:292–297 (1970).
  Article CAS PubMed Google Scholar
• M. Lippman and E. B. Thompson. The role of transcription in glucocorticoid mediated enzyme induction: Tyrosine aminotransferase induction in hepatoma tissue culture cells.J. Steroid Biochem. 5:461–465 (1974).
  Article CAS PubMed Google Scholar
• W. Rosner. Recent studies on the binding of cortisol in serum.J. Steroid Biochem. 3:531–542 (1972).
  Article CAS PubMed Google Scholar
• G. P. Lewis, W. J. Jusko, C. W. Burke, and L. Graves. Prednisolone side-effects and serum protein levels.Lancet 2:778–781 (1971).
  Article CAS PubMed Google Scholar
• P. L. Ballard. Delivery and transport of glucocorticoids to target cells.Monogr. Endocrinol. 12:25–48 (1971).
  Article Google Scholar
• A. Munck and T. Brink-Johnsen. Specific and nonspecific physiochemical interactions of glucocorticoids and related steroids with rat thymus cells_in vitro_.J. Biol. Chem. 243:5556–5565 (1968).
  CAS PubMed Google Scholar
• E. Bloom, D. T. Matulich, N. C. Lan, S. J. Higgins, S. S. Simons, and J. D. Baxter. Nuclear binding of glucocorticoid receptors: Relations between cytosol binding, activation and the biological response.J. Steroid Biochem. 12:175–184 (1980).
  Article CAS PubMed Google Scholar
• A. Munck and W. J. Holbrook. Glucocorticoid-receptor complexes in rat thymus cells.J. Biol. Chem. 259:820–831 (1984).
  CAS PubMed Google Scholar
• P. A. Bell and A. Munck. Steroid-binding properties and stabilization of cytoplasmic glucocorticoid receptors from rat thymus cells.Biochem. J. 136:97–107 (1973).
  CAS PubMed Central PubMed Google Scholar
• J. A. Goidl, M. H. Cake, K. P. Dolan, L. G. Parchman, and G. Litwack. Activation of the rat liver glucocorticoid-receptor complex.Biochemistry 16:2125–2130 (1977).
  Article CAS PubMed Google Scholar
• H. M. Westphal and M. Beato. The activated glucocorticoid receptor of rat liver.Eur. J. Biochem. 106:395–403 (1980).
  Article CAS PubMed Google Scholar
• M. Koblinsky, M. Beato, M. Kalimi, and P. Feigelson. Glucocorticoid binding proteins of rat liver cytosol. II. Physical characterization and properties of the binding proteins.J. Biol. Chem. 247:7897–7904 (1972).
  CAS PubMed Google Scholar
• A. Munck, C. Wira, D. A. Young, K. M. Mosher, C. Hallahan, and P. A. Bell. Glucocorticoid-receptor complexes and the earliest steps in the action of glucocorticoids on thymus cells.J. Steroid Biochem. 3:567–578 (1972).
  Article CAS PubMed Google Scholar
• J. L. Middlebrook, M. D. Wong, D. N. Ishii, and L. Aronow. Subcellular distribution of glucocorticoid receptors in mouse fibroblasts.Biochemistry 14:180–186 (1975).
  Article CAS PubMed Google Scholar
• M. Izawa, Y. Satoh, and S. Ichii. Recycling of steroid hormones. In H. Imura and H. Kuzuya (eds.),Hormone Receptors and Receptor Diseases, Excerpta Medica, Amsterdam, 1983, pp. 127–135.
  Google Scholar
• W. R. McIntyre and H. H. Samuels. Triamcinolone acetonide regulates glucocorticoidreceptor levels by decreasing the half-life of the activated nuclear-receptor form.J. Biol. Chem. 260:418–427 (1985).
  CAS PubMed Google Scholar
• F. D. Boudinot. The role of protein binding in prednisolone pharmacodynamics. Ph.D. thesis, State University of New York at Buffalo (1986).
  Google Scholar
• H. G. Morris. Mechanisms of action and therapeutic role of corticosteroids in asthma.J. Allergy Clin. Immunol. 75:1–13 (1985).
  Article CAS PubMed Google Scholar