Aberrations of theAPC gene in primary breast carcinoma (original) (raw)

References

• Ali IU, Lidereau R, Theillet C, Callahan R (1987) Reduction to homozygosity of genes on chromosome 11 in human breast neoplasia. Science 238:185–188.
  PubMed Google Scholar
• Baker SJ, Preisinger AC, Jessup JM, Paraskeva C, Markwitz S, Willson JKV, Hamilton S, Vogelstein B (1990) p53 gene mutations occur in combination with 17p allelic deletions as late events in colorectal tumorigenesis. Cancer Res 50:7717–7722
  PubMed Google Scholar
• Bieche I, Champeme M-H, Matifas F, Cropp CS, Callahan R, Lidereau R (1993) Two distinct regions involved in 1p deletion in human primary breast cancer. Cancer Res 53:1990–1994
  PubMed Google Scholar
• Borg A, Zhang Q-X, Alm P, Olsson H, Sellberg G (1992) The retinoblastoma gene in breast cancer: allele loss is not correlated with loss of gene protein expression. Cancer Res 52:2991–2994
  PubMed Google Scholar
• Borresen A-L, Hoving E, Smith-Sorensen B, Malkin D, Lystad S, Andersen TI, Nesland JM, Isselbacher KJ, Friend SH (1991) Constant denaturant gel electrophoresis as a rapid screening technique for p53 mutations. Proc Natl Acad Sci USA 88:8405–8409
  PubMed Google Scholar
• Boynton RF, Blount PL, Yin J, Brown VL, Huang Y, Tong Y, Tong Y, McDaniel T, Newkirk C, Resau JH, Raskind WH, Haggitt RC, Reid BJ, Meltzer SJ (1992) Loss of heterozygosity involving the_APC_ and_MCC_ genetic loci occurs in the majority of human esophageal cancers. Proc Natl Acad Sci USA 89:3385–3388
  PubMed Google Scholar
• Chen L-C, Dollbaum C, Smith HS (1989) Loss of heterozygosity on chromosome 1q in human breast cancer. Proc Natl Acad Sci USA 86:7204–7207
  PubMed Google Scholar
• Chen L-C, Neubauer A, Kurisu W, Waldman FM, Ljung B-M, Goodson W III, Goldman ES, Moore D II, Balazs M, Liu E, Mayall BH, Smith HS (1991) Loss of heterozygosity on the short arm of chromosome 17 is associated with high proliferative capacity and DNA aneuploidy in human breast cancer. Proc Natl Acad Sci USA 88:3847–3851
  PubMed Google Scholar
• D'Amico D, Carbone DP, Johnson BE, Meltzer SJ, Minna JD (1992) Polymorphic sites within the_MCC_ and_APC_ loci reveal very frequent loss of heterozygosity in human small cell lung cancer. Cancer Res 52:1996–1999
  PubMed Google Scholar
• Ding S-F, Habib NA, Dooley J, Wood C, Bowles L Delhanty JDA (1991) Loss of constitutional heterozygosity on chromosome 5q in hepatocellular carcinoma without cirrhosis. Br J Cancer 64:1083–1087
  PubMed Google Scholar
• Fujimori M, Tokino T, Hino O, Kitagawa T, Imamura T, Okamoto E, Mitsunobu M, Ishikawa T, Nakagawa H, Harada H, Yagura M, Matssubara K, Nakamura Y (1991) Allelotype study of primary hepatocellular carcinoma. Cancer Res 51:89–93
  PubMed Google Scholar
• Greewald BD, Harpaz N, Yin J, Huang Y, Tong Y, Brown VL, McDaniel T, Newkirk C, Resau JH, Meltzer SJ (1992) Loss of heterozygosity affecting the_p53, Rb_ and_mcc/apc_ tumor suppressor gene loci in dysplastic and cancerous ulcerative colitis. Cancer Res 52:741–745
  PubMed Google Scholar
• Groden J, Thliveris A, Samowitz W, Carlson M, Gelbert L, Albertsen H, Joslyn G, Stevens J, Spirio L, Robertson M, Sargeant L, Krapcho K, Wolff E, Burt R, Hughes JP, Warrington J, McPherson J, Wasmuth J, Le Paslier D, Abderrahim H, Cohen D, Leppert M, White R (1991) Identification and characterization of the familial adenomatous polyposis coli gene. Cell 66:589–600
  PubMed Google Scholar
• Horii A, Nakatsuru S, Miyoshi Y, Ichii S, Nagase H, Ando H, Yanagisawa A, Tsuchiya E, Kato Y, Nakamura Y (1992a) Frequent somatic mutations of the_APC_ gene in human pancreatic cancer. Cancer Res 52:6696–6698
  PubMed Google Scholar
• Horii A, Nakatsuru S, Miyoshi Y, Ichii S, Nagase H, Kato Y, Yanagisawa A, Nakamura Y (1992b) The_APC_ gene, responsible for familial adenomatous polyposis, is mutated in human gastric cancer. Cancer Res 52:3231–3233
  PubMed Google Scholar
• Joslyn G, Carlson M, Thliveris A, Albertsen H, Gelbert L, Samowitz W, Groden J, Stevens J, Spirio L, Robertson M, Sargeant L, Krapcho K, Wolff E, Burt R, Hughes JP, Warrington J, McPherson J, Wasmuth J, Lepaslier D, Abderrahim H, Cohen D, Leppert M, White R (1991) Identification of deletion mutations and three new genes at the familial polyposis locus. Cell 66:601–613
  PubMed Google Scholar
• Kinzler K, Nilbert MC, Su L-K, Vogelstein B, Byyan TM, Levy DB, Smith KJ, Preisinger AC, Hedge P, McKechnie D, Finniear R, Markham A, Groffen J, Miyoshi Y, Miki Y, Nishisho I, Nakamura Y (1991) Identification of FAP locus genes from chromosome 5q21. Science 253:661–665
  PubMed Google Scholar
• Knudson AG JR (1971) Mutation and cancer: statistical study of retinoblastoma. Proc Natl Acad Sci USA 68:820–823
  PubMed Google Scholar
• Lundberg C, Skoog L, Cavenee WK, Nordenskjold M (1987) Loss of heterozygosity in human ductal tumors indicates a recessive mutation on chromosome 13. Proc Natl Acad Sci USA 84:2372–2376
  PubMed Google Scholar
• Mackay J, Steel CM, Elder PA, Forrest APM, Evans HJ (1988a) Allele loss on short arm of chromosome 17 in breast cancers. Lancet II:1384–1385
  Google Scholar
• Mackay J, Elder PA, Porteous DJ, Steel CM, Hawkins RA, Going JJ, Chetty U (1988b) Partial deletion of chromosome 11p in breast cancer correlates with size of primary tumor and oestrogen receptor level. Br J Cancer 58:710–714
  PubMed Google Scholar
• Miyoshi Y, Ando H, Nagase H, Nishisho I, Horii A, Miki Y, Mori T, Utsunomiya J, Baba S, Peterson G, Hamilton SR, Kinzler KW, Vogelstein B, Nakamura Y (1992a) Germline-mutations of the_APC_ gene in 53 familial adenomatous polyposis patients. Proc Natl Acad Sci USA 89:4452–4456
  PubMed Google Scholar
• Miyoshi Y, Nagase H, Ando H, Horii A, Ichii S, Nakatsuru S, Aoki T, Miki Y, Mori T, Nakamura Y (1992b) Somatic mutations of the_APC_ gene in colorectal tumors: mutation cluster region in the_APC_ gene. Hum Mol Genet 1:229–233
  PubMed Google Scholar
• Morita R, Saito S, Ishikawa J, Ogawa O, Yoshida O, Yamakawa K, Nakamura Y (1991) Common regions of deletion on chromosome 5q, 6q, and 10q in renal cell carcinoma. Cancer Res 51:5817–5820
  PubMed Google Scholar
• Nigro JM, Baker SJ, Preisinger AC, Jessup JM, Hostetter R, Cleary K, Bigner SH, Davidson N, Baylin S, Devilee P, Glover T, Collins FS, Weston A, Modili R, Harris CC, Vogelstein B (1989) Mutations in the p53 gene occur in diverse human tumor types. Nature 343:705–708
  Google Scholar
• Nishisho I, Nakamura Y, Miyoshi Y, Miki Y, Ando H, Horii A, Koyama K, Utsunomiya J, Baba S, Hedge P, Markham A, Krush AJ, Petersen G, Hamilton SR, Nirbert MC, Levy DB, Bryan TM, Preisinger AC, Smith KJ, Su L-K, Kinzler KW, Vogelstein B (1991) Mutations of chromosome 5q21 genes in FAP and colorectal cancer patients. Science 253:665–669
  PubMed Google Scholar
• Ogasawara S, Maesawa C, Tamura G, Satodate R (1994) Lack of mutations of the adenomatous polyposis coli gene in oesophageal and gastric carcinomas. Virchows Arch 424:607–611
  PubMed Google Scholar
• Osborne RJ, Merlo GR, Mitsudomi T, Venesio T, Liscia DS, Cappa APM, Chiba I, Takahashi T, Nau MM, Callahan R, Minna JD (1991) Mutations in the p53 gene in primary breast cancers. Cancer Res 51:6194–6198
  PubMed Google Scholar
• Powell SM, Zilz N, Beazer-Barclay Y, Bryan TM, Hamilton SR, Thibodeau SN, Vogelstein B, Kinzler KW (1992)APC mutations occur early during colorectal tumorigenesis. Nature 359:235–237
  PubMed Google Scholar
• Sano T, Tsujono T, Yoshida K, Nakayama H, Haruma K, Ito H, Nakamura Y, Kajiyama G, Tahara E (1991) Frequent loss of heterozygosity on chromosomes 1q, 5q, and 17p in human gastric carcinomas. Cancer Res 51:2926–2931
  PubMed Google Scholar
• Sato T, Tanigami A, Yamakawa K, Akiyama F, Kasumi F, Sakamoto G, Nakamura Y (1990) Allelotype of breast cancer: cumulative allele losses promote tumor progression in primary breast cancer. Cancer Res 50:7184–7189
  PubMed Google Scholar
• Sato T, Akiyama F, Sakamoto G, Kasumi F, Nakamura Y (1991) Accumulation of genetic alterations and progression of primary breast cancer. Cancer Res 51:5794–5799
  PubMed Google Scholar
• Su L-K, Johnson KA, Smith KJ, Hill DE, Vogelstein B, Kinzler KW (1993) Association between wild type and mutant_APC_ gene products. Cancer Res 53:2728–2731
  PubMed Google Scholar
• Suzuki Y, Sekiya T, Hayashi K (1991) Allele-specific polymerase chain reaction: a method for amplification and sequence determination of a single component among a mixture of sequence variants. Anal Biochem 192:82–84
  PubMed Google Scholar
• Takita K, Sato T, Miyagi M, Watatani M, Akiyama F, Sakamoto G, Kasumi F, Abe R, Nakamura Y (1992) Correlation of loss of alleles on the short arms of chromosomes 11 and 17 with metastasis of primary breast cancer to lymph nodes. Cancer Res 52: 3914–3917
  PubMed Google Scholar
• Tamura G, Kihara T, Nomura K, Terada M, Sugimura T, Hirohashi S (1991) Detection of frequent p53 gene mutations in primary gastric cancer by cell sorting and polymerase chain reaction singlestrand conformation polymorphism analysis. Cancer Res 51:3056–3058
  PubMed Google Scholar
• Tamura G, Maesawa C, Suzuki Y, Ogasawara S, Terashima M, Saito K, Satodate R (1993) Primary gastric carcinoma cells frequetly lose heterozygosity at the APC and MCC genetic loci. Jpn J Cancer Res 84:1015–1018
  PubMed Google Scholar
• Theillet C, Lidereau R, Escot C, Hutzell P, Brunet M, Gest J, Schlom J, Callahan R (1986) Loss of a c-H-_ras_-1 allele and aggressive human primary breast carcinomas. Cancer Res 46:4776–4781
  PubMed Google Scholar
• Thompson AM, Morris RG, Wallace M, Wyllie AH, Steel CM, Carter DC (1993) Allele loss from 5q21 (APC/MCC) and 18q21 (DCC) and DCC mRNA expression in breast cancer. Br J Cancer 68:64–68
  PubMed Google Scholar
• Tsuchiya E, Nakamura Y, Weng S-Y, Nakagawa K, Tsuchiya S, Sugano H, Kitagawa T (1992) Allelotype of non-small cell lung carcinoma — comparison between loss of heterozygosity in squamous cell carcinoma and adenocarcinoma. Cancer Res 52:2478–2481
  PubMed Google Scholar
• Varesco L, Gismondi V, James R, Robertson M, Grammatico P, Groden J, Casarino L, De Benedetti L, Bafico A, Bertario L, Sala P, Sassatelli R, Ponz de Leon M, Biasco G, Allegretti A, Aste H, De Sanctis S Rossetti C, Illeni MT, Sciarra A, Del Porto G, White R, Ferrara GB (1993) Identification of_APC_ gene mutations in Italian adenomatous polyposis coli patients by PCR-SSCP analysis. Am J Hum Genet 52:280–285
  PubMed Google Scholar
• Varley JM, Brammar WJ, Lane DP, Swallow JE, Dolan C, Walker RA (1991) Loss of chromosome 17p13 sequences and mutation of p53 in human breast carcinomas. Oncogene 6:413–421
  PubMed Google Scholar

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