Radiotherapy after hyperbaric oxygenation for malignant gliomas: a pilot study (original) (raw)

Abstract

The results of radiotherapy combined with hyperbaric oxygen in 9 patients with malignant glioma were compared with those of radiotherapy without hyperbaric O2 in 12 patients. This is the first report of a pilot study of irradiation immediately after exposure to hyperbaric O2 in humans. All patients receiving this treatment showed more than 50% regression of the tumor, and in 4 of them, the tumors disappeared completely. Only 4 out of 12 patients without hyperbaric O2 showed decreases in tumor size, and all 12 patients died within 36 months. So far, this new regimen seems to be a useful form of radiotherapy for malignant gliomas.

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Authors and Affiliations

1. Department of Neurosurgery, University of Occupational and Environmental Health, 1-1 Iseigaoka, Yahatanishi-ku, 807, Kitakyushu, Japan
   Kiyotaka Kohshi & Yoshimasa Kinoshita
2. Department of Hyperbaric Medicine, University of Occupational and Environmental Health, 807, Kitakyushu, Japan
   Kiyotaka Kohshi & Nobuhide Konda
3. Department of Radiology, University of Occupational and Environmental Health, 807, Kitakyushu, Japan
   Hiromi Terashima
4. Department of Neurosurgery, Moji Rosai Hospital, 3-1 Higashi-Minato-machi, Moji-ku, 801, Kitakyushu, Japan
   Akira Yokota & Tohru Soejima

Authors

1. Kiyotaka Kohshi
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2. Yoshimasa Kinoshita
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3. Hiromi Terashima
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4. Nobuhide Konda
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5. Akira Yokota
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6. Tohru Soejima
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Kohshi, K., Kinoshita, Y., Terashima, H. et al. Radiotherapy after hyperbaric oxygenation for malignant gliomas: a pilot study.J Cancer Res Clin Oncol 122, 676–678 (1996). https://doi.org/10.1007/BF01209031

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• Received: 21 March 1996
• Accepted: 11 June 1996
• Issue Date: November 1996
• DOI: https://doi.org/10.1007/BF01209031

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