Effects of streptozotocin in vitro on proinsulin biosynthesis, insulin release and ATP content of isolated rat islets of Langerhans (original) (raw)

References

  1. Herr, R.R., Eble, T.E., Bergy, M.E., Jahnke, H.K.: Isolation and characterization of streptozotocin. In: Antibiotics annual, pp. 236–240. New York: Antibiotica Inc. 1959–1960
    Google Scholar
  2. Vavra, J.J., DeBoer, C., Dietz, A., Hanka, L.J., Sokolski, W.T.: Streptozotocin: a new antibacterial antibiotic. In: Antibiotics annual, pp. 230–235. New York: Antibiotica Inc. 1959–1960
    Google Scholar
  3. Evans, J.S., Gerritsen, G.D., Mann, K.M., Owen, S.P.: Antitumor and hyperglycemic activity of streptozotocin (NSC 37917) and its cofactor, U 15 774. Cancer Chemother. Rep.48, 1–6 (1965)
    Google Scholar
  4. Rakietene, N., Rakieten, M.L., Nadkarni, V.: Studies on the diabetogenic action of streptozotocin. Cancer Chemother. Rep.29, 91–98 (1963)
    Google Scholar
  5. Herr, R.R., Jahnke, H.K., Argoudelis, A.D.: The structure of streptozotocin, J. Amer. chem. Soc.89, 4808–4809 (1967)
    Google Scholar
  6. Junod, A., Lambert, A.E., Orci, L., Pictet, R., Gonet, A.E., Renold, A.E.: Studies on the diabetogenic action of streptozotocin. Proc. Soc. exp. Biol. (N.Y.)126, 201–205 (1967)
    Google Scholar
  7. Junod, A., Lambert, A.E., Stauffacher, W., Renold, A.E.: Diabetogenic action of streptozotocin: Relationship of dose to metabolic response. J. clin. Invest.48, 2129–2139 (1969)
    Google Scholar
  8. Brosky, G., Logothetopoulos, J.: Streptozotocin diabetes in the mouse and guinea pig. Diabetes18, 606–611 (1969)
    Google Scholar
  9. Pitkin, R.M., Reynolds, W.A.: Diabetogenic effects of streptozotocin in rhesus monkeys. Diabetes19, 85–90 (1970)
    Google Scholar
  10. Schein, P.S., Alberti, K.G.M. M., Williamson, D. H.: Effects of streptozotocin on carbohydrate and lipid metabolism in the rat. Endocrinology89, 827–934 (1971)
    Google Scholar
  11. Sybulski, S., Maughan, G.B.: Use of streptozotocin as diabetic agent in pregnant rats. Endocrinology89, 1537–1540 (1971)
    Google Scholar
  12. Lazarus, S.S., Shapiro, S.H.: Streptozotocin-induced diabetes and islet cell alterations in rabbits. Diabetes21, 129–137 (1972)
    Google Scholar
  13. Dixit, P.K., Tam, B.B., Hernandez, R.E.: Comparison of the effect of diabetogenic agents on the microdissected pancreatic islet tissue of the rat. Proc. Soc. exp. Biol. (N.Y.)140, 1418–1423 (1972)
    Google Scholar
  14. Zapf, J., Waldvogel, M., Froesch, E.R.: Protein kinase and cyclic-AMP binding activities in liver and adipose tissue of normal, streptozotocin-diabetic and adrenalectomized rats. FEBS Letters36, 253–256 (1973)
    Google Scholar
  15. Reaven, E.P., Reaven, G.M.: Mechanisms for development of diabetic hypertriglyceridemia in streptozotocin-treated rats. J. clin. Invest.54, 1167–1178 (1974)
    Google Scholar
  16. Renold, A.E., Rabinovitch, A., Wollheim, C., Kikuchi, M., Gutzeit, A., Amherdt, M., Malaisse-Lagae, F., Orci, L.: Spontaneous and experimental diabetic syndromes in animals. A re-evaluation of their usefulness for approaching the physiopathology of diabetes. Excerpta Medica International Congress Series312, pp. 22–38. Amsterdam 1974
    Google Scholar
  17. Schein, P.S., Cooney, D.A., Vernon, M.L.: The use of nicotinamide to modify the toxicity of streptozotocin diabetes without loss of antitumoral activity. Cancer Res.27, 2324–2332 (1967)
    Google Scholar
  18. Schein, P.S., Loftus, S.: Streptozotocin: Depression of mouse liver pyridine nucleotides. Cancer Res.28, 1501–1506 (1968)
    Google Scholar
  19. Dulin, W.E., Wyse, B.M.: Studies on the ability of compounds to block the diabetogenic activity of streptozotocin. Diabetes18, 459–466 (1969)
    Google Scholar
  20. Stauffacher, W., Burr, I., Gutzeit, A., Beaven, D., Veleminsky, J., Renold, A.E.: Streptozotocin diabetes: Time course of irreversible B-cell damage; further observations on prevention by nicotinamide. Proc. Soc. exp. Biol. (N.Y.)133, 194–200 (1970)
    Google Scholar
  21. Stauffacher, W., Balant, L., Amherdt, D.P., Cameron, L., Orci, L.: Mode of action of streptozotocin: indication for accelerated NAD destruction. Diabetologia8, (Abstr.) 68 (1972)
    Google Scholar
  22. Chang, A.Y.: On the mechanism for the depression of liver NAD by streptozotocin. Biochem. biophys. Acta (Amst.)261, 77–84 (1972)
    Google Scholar
  23. Lazarus, S.S., Shapiro, S.H.: Influence of nicotinamide and pyridine nucleotides on streptozotocin and alloxan-induced pancreatic B-cell cytotoxicity. Diabetes22, 499–506 (1973)
    Google Scholar
  24. Gunnarson, R., Berne, C., Hellerstrom, G.: Cytotoxic effects of streptozotocin and N-nitrosomethylurea on the pancreatic B-cells, with special regard to the role of nicotinamide adenine dinucleotide. Biochem. J.140, 487–494 (1974)
    Google Scholar
  25. Anderson, T., Schein, P.S., McMenamin, M.G., Cooney, D. A.: Streptozotocin diabetes: Correlation with extent of depression of pancreatic islet nicotinamide adenine dinucleotide. J. clin. Invest.54, 672–677 (1974)
    Google Scholar
  26. Rakieten, N., Gordon, B.S., Beaty, A., Cooney, D.A., Davis, R.D., Schein, P. S.: Pancreatic islet cell tumors produced by the combined action of streptozotocin and nicotinamide. Proc. Soc. exp. Biol. (N. Y.)137, 280–283 (1971)
    Google Scholar
  27. Volk, B.W., Wellmann, K.F., Brancato, P.: Fine structure of rat islet cell tumors induced by streptozotocin and nicotinamide. Diabetologia10, 37–44 (1973)
    Google Scholar
  28. Wyse, B.M., Dulin, W.E.: The effects of streptozotocin on glucose oxidation by isolated islets of Langerhans. Proc. Soc. exp. Biol. (N.Y.)136, 70–72 (1971)
    Google Scholar
  29. Golden, P., Baird, L., Malaisse, W.J., Malaisse-Lagae, F.: Effect of streptozotocin on glucose-induced insulin secretion by isolated islets of Langerhans. Diabetes20, 513–518 (1971)
    Google Scholar
  30. Taylor, K.W.: Regulation of insulin synthesis: International Congress of Endocrinology III, pp. 220–224. (1968)
    Google Scholar
  31. Lacy, P.E., Kostianovsky, M.: Method for the isolation of intact islets of Langerhans from the rat pancreas. Diabetes16, 35–39 (1967)
    Google Scholar
  32. Eagle, H.: Amino-acid metabolism in mammalian cell cultures. Science130, 432–437 (1959)
    Google Scholar
  33. Davoren, P.R.: The isolation of insulin from a single cat pancreas. Biochim. biophys. acta (Amst.)63, 150–153 (1962)
    Google Scholar
  34. Permutt, M.A., Kipnis, D.M.: Insulin biosynthesis. On the mechanism of glucose stimulation. J. biol. Chem.247, 1194–1199 (1972)
    Google Scholar
  35. Pipeleers, D.G., Marichal, M., Malaisse, W.J.: The stimulus-secretion coupling of glucose-induced insulin release. XIV. Glucose regulation of insular biosynthetic activity. Endocrinology93, 1001–1011 (1973)
    Google Scholar
  36. Herbert, V., Lau, K.S., Gottlieb, C.W., Bleicher, S.J.: Coated charcoal immunoassay of insulin. J. clin. Endocr.25, 1375–1384 (1965)
    Google Scholar
  37. Greenwood, F.C., Hunter, W.M., Glover, J.S.: The preparation of I-131-labelled human growth hormone of high specific radioactivity. Biochem. J.89, 114–123 (1963)
    Google Scholar
  38. Strehler, B.L., Totter, J.R.: Determination of ATP and related compounds: Firefly luminescence and other methods. In: Methods of biochemical analysis, Vol. 1, (ed. D. Glick), p. 341. New York: Interscience
  39. Wettermark, G., Tegnér, L., Brolin, S.E., Borglund, E.: Photokinetic measurements of the ATP and ADP levels in isolated islets of Langerhans. In: The structure and metabolism of the pancreatic islets, Werner-Gren Symposium N. 16. (eds. G. Falkner, B. Hellman, I.B. Täljedal). Oxford: Pergamon Press 1970
    Google Scholar
  40. Ashcroft, S.J. H., Weerasinghe, L.C.C. Randle, P.J.: Interrelationship of islet metabolism, adenosine triphosphate content and insulin release. Biochem. J.132, 223–231 (1973)
    Google Scholar
  41. Hellman, B.: The relation between age and the B/A cell ratio in the islet tissue of the rat. Acta endocr. (Kbh.)31, 80–90 (1959)
    Google Scholar
  42. Hellman, B.: The effect of ageing on the total volumes of the A and B cells in the islets of Langerhans of the rat. Acta endocr. (Kbh.)32, 92–112 (1959)
    Google Scholar
  43. Karunanayake, E.H., Hearse, D.J., Mellows, G.: The synthesis of (14C)-streptozotocin and its distribution and excretion in the rat. Biochem. J.142, 673–683 (1974)
    Google Scholar
  44. Sando, H., Borg, J., Steiner, D.F.: Studies on the secretion of newly synthesized proinsulin and insulin from isolated rat islets of Langerhans. J. clin. Invest.51, 1476–1485 (1972)
    Google Scholar

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