Irritable bowel syndrome (original) (raw)

Abstract

Patients with different irritable bowel symptoms and normal subjects were compared to determine whether subtypes of irritable bowel syndrome (IBS) could be distinguished on the basis of colonic motility or psychological test scores. A provocative test involving stepwise distension of the rectosigmoid area revealed two types of colonic motility. Slow contractions having durations of at least 15 sec and occurring at irregular intervals were more frequent in IBS patients than in normals but did not differentiate constipation from diarrhea. Fast contractions having durations of less than 15 sec and occurring in runs at frequencies of 6–9 cpm were more frequent in patients with diarrhea than in normals or constipated IBS patients. Constipated patients showed no more fast contractions than normals. Severity of bowel symptoms was correlated with the overall amount of motility (motility index) in patients with diarrhea but not in patients with constipation. Patients with IBS showed significantly elevated levels on the following psychological traits: anxiety, interpersonal sensitivity, depression, hostility, and somatization of affect. However, there were no significant trait differences between patients with diarrhea and those with constipation. Also, there was no correlation between amount of psychopathology and either colonic motility or severity of symptoms in the whole group of IBS patients.

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Authors and Affiliations

  1. Hohns Hopkins University School of Medicine, National Institute on Aging, National Institutes of Health, PHS, U.S. Department of Health, Education and Welfare, Bethesda
    William E. Whitehead PhD, Bernard T. Engel PhD & Marvin M. Schuster MD
  2. Laboratory of Behavioral Sciences, Gerontology Research Center, (Baltimore)
    William E. Whitehead PhD, Bernard T. Engel PhD & Marvin M. Schuster MD
  3. Division of Digestive Diseases, Baltimore City Hospital, 21224, Baltimore, Maryland
    William E. Whitehead PhD, Bernard T. Engel PhD & Marvin M. Schuster MD

Authors

  1. William E. Whitehead PhD
  2. Bernard T. Engel PhD
  3. Marvin M. Schuster MD

Additional information

Supported by Research Scientist Development Award 1 K01 MH00133 to William E. Whitehead and by the Intramural Research Program of the National Institute on Aging.

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Whitehead, W.E., Engel, B.T. & Schuster, M.M. Irritable bowel syndrome.Digest Dis Sci 25, 404–413 (1980). https://doi.org/10.1007/BF01395503

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