Evolutionary trees with minimum nucleotide replacements from amino acid sequences (original) (raw)

Summary

The problem of determining the minimum number of nucleotide substitutions required to account for the descent of a set of amino acid sequences given their ancestral relationships (phylogeny) has been studied. A method expanding upon the earlier work of Fitch (1971) for a set of nucleotide sequences is presented and its merits compared to the method of Moore_et al._ (1973).

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Authors and Affiliations

  1. Department of Physiological Chemistry, University of Wisconsin, 53706, Madison, Wisconsin, USA
    Walter M. Fitch
  2. Department of Ecology and Evolution, State University of New York at Stoney Brook, 11790, Stoney Brook, New York, USA
    James S. Farris

Authors

  1. Walter M. Fitch
  2. James S. Farris

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Fitch, W.M., Farris, J.S. Evolutionary trees with minimum nucleotide replacements from amino acid sequences.J Mol Evol 3, 263–278 (1974). https://doi.org/10.1007/BF01796042

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