Immunopathology of leprosy granulomas (original) (raw)

References

1. Alvarenga FdeB, Sarno EN, Figueiredo AdeA, Gattass CR, Porto JA (1985) Distribution of Langerhans cells in the skin of patients with Hansen's disease. Med Cutan Ibero Lat Am 13: 187
   PubMed Google Scholar
2. Beck JS, Morley SM, Gibbs JH, Potts RC, Ilias MI, Kardjito T, Grange JM, Stanford J, Brown RA (1986) The cellular responses of tuberculosis and leprosy patients and of healthy controls in skin tests to ‘new tuberculin’ and leprosin A. Clin Exp Immunol 64: 484
   PubMed Google Scholar
3. Bloom BR (1986) Learning from leprosy: a perspective on immunology and the third world. J Immunol 137: i
   PubMed Google Scholar
4. Bloom BR, Mehra V (1984) Immunological unresponsiveness in leprosy. Immunol Rev 80: 5
   PubMed Google Scholar
5. Collings LA, Tidman N, Poulter LW (1985) Quantitation of HLA-DR expression by cells involved in the skin lesions of tuberculoid and lepromatous leprosy. Clin Exp Immunol 61: 58
   PubMed Google Scholar
6. Collings LA, Waters MF, Poulter LW (1985) The involvement of dendritic cells in the cutaneous lesions associated with tuberculoid and lepromatous leprosy. Clin Exp Immunol 62: 458
   PubMed Google Scholar
7. Convit J, Pinardi ME, Rodriguez Ochoa G, Ulrich M, Avila JL, Goihman M (1974) Elimination of_Mycobacterium leprae_ subsequent to local in vivo activation of macrophages in lepromatous leprosy by other mycobacteria. Clin Exp Immunol 17: 261
   PubMed Google Scholar
8. Damle NK, Childs AL, Doyle LV (1987) Immunoregulatory T lymphocytes in man. Soluble antigen-specific suppressor-inducer T lymphocytes are derived from the CD4+CD45R-p80+ subpopulations. J Immunol 139: 1501
   PubMed Google Scholar
9. Dugan E, Modlin RL, Rea TH (1985) An in situ immunohistological study of Mitsuda reactions. Int J Lepr 53: 404
   Google Scholar
10. Haregewoin A, Godal T, Mustafa AS, Belehu A, Yemaneberhan T (1983) T cell-conditioned media reverse T cell unresponsiveness in lepromatous leprosy. Nature 303: 342
    PubMed Google Scholar
11. Kaplan G, Cohn ZA (1986) Regulation of cell-mediated immunity in lepromatous leprosy. Lepr Rev [Suppl 2] 57: 199
    Google Scholar
12. Kaplan G, Witmer MD, Nath I, Steinman RM, Laal S, Prasad HK, Sarno EN, Elvers U, Cohn ZA (1986) Influence of delayed immune reactions on human epidermal keratinocytes. Proc Natl Acad Sci USA 83: 3469
    PubMed Google Scholar
13. Kaplan G, Luster AD, Hancock G, Cohn ZA (1987) The expression of a gamma interferon-induced protein (IP-10) in delayed immune responses in human skin. J Exp Med 166: 1098
    PubMed Google Scholar
14. Kaplan G, Nusrat A, Witmer MD, Nath I, Cohn ZA (1987) Distribution and turnover of Langerhans cells during delayed immune responses in human skin. J Exp Med 165: 173
    PubMed Google Scholar
15. Kato H, Sanada K, Koseki M, Ozawa T (1983) Identification of lymphocyte subpopulations in cutaneous lesions of leprosy. Nippon Rai Gakkai Zasshi 52: 126
    PubMed Google Scholar
16. Katz SI (1985) The skin as an immunologic organ. J Am Acad Dermatol 13: 530
    PubMed Google Scholar
17. Kikuchi I, Ozawa T, Hirayama K, Sasazuki T (1986) An HLA-linked gene controls susceptibility to lepromatous leprosy through T cell regulation. Lepr Rev [Suppl 2] 57: 139
    PubMed Google Scholar
18. Longley J, Haregewoin A, Yemaneberhan T, van Diepen TW, Nsibami J, Knowles D, Smith KA, Godal T (1985) In vivo responses to Mycobacterium leprae: antigen presentation, interleukin-2 production, and immune cell phenotypes in naturally occuring leprosy lesions. Int J Lepr 53: 385
    Google Scholar
19. Longley BJ, Haregewoin A, DeBaumount W, Smith KA, Godal T (1986) Lepromin stimulates interleukin-2 production and interleukin-2 receptor expression in situ in lepromatous leprosy patients. Lepr Rev [Suppl 2] 57: 189
    PubMed Google Scholar
20. Modlin RL, Hofman FM, Taylor CR, Rea TH (1982) In situ characterization of T lymphocyte subsets in leprosy granulomas [letter]. Int J Lepr 50: 361
    Google Scholar
21. Modlin RL, Gebhard JF, Taylor CR, Rea TH (1983) In situ characterization of T lymphocyte subsets in the reactional states of leprosy. Clin Exp Immunol 53: 17
    PubMed Google Scholar
22. Modlin RL, Hofman FM, Meyer PR, Sharma OP, Taylor CR, Rea TH (1983) In situ demonstration of T lymphocyte subsets in granulomatous inflammation: leprosy, rhinoscleroma and sarcoidosis. Clin Exp Immunol 51: 430
    PubMed Google Scholar
23. Modlin RL, Hofman FM, Taylor CR, Rea TH (1983) T lymphocyte subsets in the skin lesions of patients with leprosy. J Am Acad Dermatol 8: 182
    PubMed Google Scholar
24. Modlin RL, Hofman FM, Horwitz DA, Husmann LA, Gillis S, Taylor CR, Rea TH (1984) In situ identification of cells in human leprosy granulomas with monoclonal antibodies to interleukin 2 and its receptor. J Immunol 132: 3085
    PubMed Google Scholar
25. Modlin RL, Rowden G, Taylor CR, Rea TH (1984) Comparison of S-100 and OKT6 antisera in human skin. J Invest Dermatol 83: 206
    PubMed Google Scholar
26. Modlin RL, Bakke AC, Vaccaro SA, Horwitz DA, Taylor CR, Rea TH (1985) Tissue and blood T-lymphocyte subpopulations in erythema nodosum leprosum. Arch Dermatol 121: 216
    PubMed Google Scholar
27. Modlin RL, Gersuk GM, Nelson EE, Pattengale PK, Gunter JR, Chen L, Cooper CL, Bloom BR, Rea TH (1986) T lymphocyte clones from leprosy skin lesions. Lepr Rev [Suppl 2] 57: 143
    PubMed Google Scholar
28. Modlin RL, Kato H, Mehra V, Nelson EE, Xue-dong F, Rea TH, Pattengale PK, Bloom BR (1986) Genetically restricted suppressor T cell clones derived from lepromatous leprosy lesions. Nature 322: 459
    PubMed Google Scholar
29. Modlin RL, Mehra V, Jordan R, Bloom BR, Rea TH (1986) In situ and in vitro characterization of the cellular immune response in erythema nodosum leprosum. J Immunol 136: 883
    PubMed Google Scholar
30. Modlin RL, Mehra V, Wong L, Fujimiya Y, Chang W-C, Horwitz DA, Bloom BR, Rea TH, Pattengale PK (1986) Suppressor T lymphocytes from lepromatous leprosy skin lesions. J Immunol 137: 2831
    PubMed Google Scholar
31. Modlin RL, Ormerod LD, Walsh GP, Rea TH, Meyers WM, Binford CH, Martin LN, Wolf RH, Gormus BJ (1986) In situ characterization of T lymphocyte subpopulations in leprosy in the mangabey monkey. Clin Exp Immunol 65: 260
    PubMed Google Scholar
32. Modlin RL, Brenner MB, Krangel MS, Duby AD, Bloom BR (1987) T cell receptors of human suppressor cells. Nature 329: 541
    PubMed Google Scholar
33. Modlin RL, Melancon-Kaplan J, Young SMM, Kino H, Convit J, Rea TH, Bloom BR (1988) Learning from lesions: patterns of tissue inflammation in leprosy. Proc Natl Acad Sci USA 85: 1213
    Google Scholar
34. Moncada B, Gonzalez Amaro R, Loredo CE, Baranda ML (1982) Langerhans cells in leprosy. Gac Med Mex 118: 497
    PubMed Google Scholar
35. Morimoto C, Letvin NL, Boyd AW, Hagan M, Brown HM, Kornacki MM, Schlossman SF (1985) The isolation and characterization of the human helper-inducer T cell subset. 134: 3762
    Google Scholar
36. Morimoto C, Letvin NL, Distaso JA, Aldrich WR, Schlossman SF (1985) The isolation and characterization of the human suppressor-inducer T cell subset. J Immunol 134: 1508
    PubMed Google Scholar
37. Narayanan RB, Bhutani LK, Sharma AK, Nath I (1983) T cell subsets in leprosy lesions: in situ characterization using monoclonal antibodies. Clin Exp Immunol 51: 421
    PubMed Google Scholar
38. Narayanan RB, Bhutani LK, Sharma AK, Nath I (1984) Normal numbers of T6 positive epidermal Langerhans cells across the leprosy spectrum. Lepr Rev 55: 301
    PubMed Google Scholar
39. Narayanan RB, Laal S, Sharma AK, Bhutani LK, Nath I (1984) Diferences in predominant T cell phenotypes and distribution pattern in reactional lesions of tuberculoid and lepromatous leprosy. Clin Exp Immunol 55: 623
    PubMed Google Scholar
40. Narayanan RB, Girhar BK, Sengupta U, Desikan KV (1985) In vitro studies on dermal granulomas of human leprosy—cellular characteristics. Int J Lepr 53: 39
    Google Scholar
41. Narayanan RB, Ramu G, Malaviya GN, Sengupta U, Desikan KV (1985) In situ characterization of cells in the dermal infiltrates of lepromin reaction using monoclonal antibodies. Indian J Lepr 57: 265
    PubMed Google Scholar
42. Narayanan RB, Girhar BK, Lavania RK, Sengupta U (1986) In vitro studies on dermal granulomas of human leprosy: characterization of cells using monoclonal antibodies. Int J Lepr 54: 268
    Google Scholar
43. Narayanan RB, Ramu G, Malaviya GN, Sinha S, Sengupta U (1986) Immunohistological analysis of skin reaction to My1 derived from_Mycobaterium leprae_. Int J Lepr 54: 46
    Google Scholar
44. Narayanan RB, Ramu G, Sinha S, Sengupta U, Gupta CM (1987) Immunohistologic comparison between armadillo-derived leprosin and standard lepromin skin tests in leprosy patients. Int Arch Allergy Immunol 82: 202
    Google Scholar
45. Nathan CF, Kaplan G, Levis WR, Nusrat A, Witmer MD, Sherwin SA, Job CK, Horowitz CR, Steinman RM, Cohn ZA (1986) Local and systemic effects of intradermal recombinant interferongamma in patients with lepromatous leprosy. N Engl J Med 315: 6
    PubMed Google Scholar
46. Nilsen R, Mshana RN, Negesse Y, Menigistu G, Kana B (1986) Immunohistochemical studies of leprous neuritis. Lepr Rev [Suppl 2] 57: 177
    PubMed Google Scholar
47. Ottenhoff THM, Elferink DG, Klaster PR, de Vries RRP (1986) Cloned suppressor T cells from a lepromatous leprosy patient supress_Mycobacterium leprae_-reactive helper T cells. Nature 322: 462
    PubMed Google Scholar
48. Poulter LW, Collings LA, Tung KS, Waters MF (1984) Parasitism of antigen-presenting cells in hyperbacillary leprosy. Clin Exp Immunol 55: 611
    PubMed Google Scholar
49. Rea TH, Shen J-Y, Modlin RL (1986) Epidermal keratonocyte Ia expression, Langerhans cell hyperplasia and lymphocytic infiltration in skin lesions of leprosy. Clin Exp Immunol 65: 253
    PubMed Google Scholar
50. Ridley DS (1972) The pathogenesis of the early lesions in leprosy. J Pathol 111: 191
    Google Scholar
51. Ridley DS, Jopling WH (1966) Classification of leprosy according to immunity. A five-group system. Int J Lepr 34: 255
    Google Scholar
52. Samuel NM, Silwal S, Samuel S, Loudon J (1985) Identification of lymphocyte subsets in leprosin A-positive sites following vaccination. Nippon Rai Gakkai Zasshi 54: 18
    PubMed Google Scholar
53. Sarno EN, Kaplan G, Alvarango F, Nogueira N, Porto JA, Cohn ZA (1984) Effect of treatment on the cellular composition of cutaneous lesions in leprosy patients. Int J Lepr 52: 496
    Google Scholar
54. Shen J-Y, Hofman FM, Gunter JR, Modlin RL, Rea TH (1987) In situ identification of activated Ta1 + T-lymphocytes in human leprosy skill lesions. Int J Lepr 55: 494
    Google Scholar
55. Smith SH, Brown MH, Rowe D, Callard RE, Beverley PCL (1986) Functional subsets of human helper-inducer cells defined by a new monoclonal antibody, UCHL1. Immunology 58: 63
    PubMed Google Scholar
56. van Voorhis WC, Kaplan G, Sarno EN, Horwitz MA, Steinman RM, Lewis WR, Nogueira N, Hair LS, Gattass CR, Arrick BA, Cohn ZA (1982) The cutaneous infiltrates of leprosy: cellular characteristics and the predominant T cell phenotypes. N Engl J Med 307: 1593
    PubMed Google Scholar
57. Wallach D, Flageul B, Bach MA, Cottenot F (1984) The cellular content of dermal leprous granulomas: an immuno-histological approach. Int J Lepr 52: 318
    Google Scholar
58. Yamada H, Martin PJ, Bean MA, Braun MP, Beatty PG, Sadamoto K, Hansen JA (1985) Monoclonal antibody 9.3 and anti-CD11 antibodies define reciprocal subsets of lymphocytes. Eur J Immunol 15: 1164
    PubMed Google Scholar

Download references