A prognostic index for patients with malignant melanoma of the conjunctiva (original) (raw)

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Abstract

From 1968 to 1984, 31 patients with histologically proven malignant melanoma of the conjunctiva were treated and followed in the Eye Hospital of the University of München. Histological demonstration of tumor thickness and the mitotic index (number of mitoses per square millimeter) gave a the prognostic index, in which tumor thickness was multiplied by the mitotic index. This index then allowed evaluation of the risk for tumor metastasis. Most tumors measured less than 1.5 mm in thickness, and the metastatic risk was low or medium in these cases. All tumors of the low metastatic risk group had a prognostic index of 1 or less, while all recurrences were associated with a prognostic index that exceeded 1.

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References

• Ash JE (1950) Epibulbar tumors. Am J Ophthalmol 33: 1203–1219
  PubMed Google Scholar
• Bernardino VB, Naidoff MA, Clark WH (1976) Malignant melanomas of the conjunctiva. Am J Ophthalmol 82: 383–394
  PubMed Google Scholar
• Brownstein S, Jakobiec FA, Wilkinson RD, Lombardo J, Jackson WB (1981) Cryotherapy for precancerous melanosis (atypical melanocytic hyperplasia), of the conjunctiva. Arch Ophthalmol 99: 1224–1231
  PubMed Google Scholar
• Clark WH (1967) A classification of malignant melanoma in man correlated with histoghenesis, and biologic behaviour. In: Montagna W, Hu F (eds) Advances in biology of the skin. The pigmentary system, vol 8. Pergamon Press, London, pp 621–647
  Google Scholar
• Crawford JB (1980) Conjunctival melanomas: prognostic factors. A review and analysis of a series. Trans Am Ophthalmol Soc 78: 467–502
  PubMed Google Scholar
• Folberg R, McLean IW, Zimmerman LE (1985) Malignant melanoma of the conjunctiva. Hum Pathol 16: 136
  PubMed Google Scholar
• Henkind P (1978) Conjunctival melanocytic lesions: natural history. In: Jakobiec FA (ed) Ocular and adnexal tumors. Aesculapius, Birmingham, Alabama, pp 572–582
  Google Scholar
• Henkind P, Benjamin JV (1978) Conjunctival melanocytic lesions. Natural history. Trans Ophthalmol Soc UK 97: 373–377
  Google Scholar
• Jakobiec FA (1980) Conjunctival melanoma. Unfinished business (editorial). Arch Ophthalmol 99: 1378–1384
  Google Scholar
• Jakobiec FA (1981) Conjunctival melanoma. (Correspondence). Arch Ophthalmol 99: 512–516
  Google Scholar
• Jakobiec FA, Brownstein S, Wilkinson RD (1980) Combined surgery and cryotherapy of diffuse malignant melanoma of the conjunctiva. Arch Ophthalmol 98: 1390–1396
  PubMed Google Scholar
• Jakobiec FA, Iwamoto T (1983) Cryotherapy for intraepithelial conjunctival melanocytic proliferations. Ultrastructural effects. Arch Ophthalmol 101: 904–912
  PubMed Google Scholar
• Jay B (1965) Naevi and melanomata of the conjunctiva. Brit J Ophthalmol 49: 169–204
  Google Scholar
• Liesegang TJ, Campbell RJ (1980) Mayo Clinic experience with conjunctival melanomas. Arch Ophthalmol 98: 1385–1399
  PubMed Google Scholar
• Schmoeckel C, Kaviani-Nejad K, Braun-Falco O (1980) Der prognostische Index beim malignen Melanom. Pathologe 1: 71–78
  PubMed Google Scholar
• Stefani FH (1984) Irisprolaps: Abtragen oder rücklagern? Zur intraoperativen Prophylaxe der Epithelimplantation. Fortschr Ophthalmol 81: 43–45
  PubMed Google Scholar
• Stefani FH (1985) Thermische Epithelabrasio bei länger bestehendem Irisprolaps nach Kataraktextraktion. Fortschr Ophthalmol 82: 265
  PubMed Google Scholar

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Authors and Affiliations

1. Eye Hospital of the University of Munich, D-8000, München, Federal Republic of Germany
   F. H. Stefani

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Stefani, F.H. A prognostic index for patients with malignant melanoma of the conjunctiva.Graefe's Arch Clin Exp Ophthalmol 224, 580–582 (1986). https://doi.org/10.1007/BF02154748

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• Received: 17 February 1986
• Accepted: 01 August 1986
• Issue date: November 1986
• DOI: https://doi.org/10.1007/BF02154748

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