Signal transduction by cGMP in heart (original) (raw)
Anand-Srivastava MB, Cantin M (1986) Atrial natriuretic factor receptors are negatively coupled to adenylate cyclase in cultured atrial and ventricular cardiocytes. Biochem Biophys Res Commun 138:427–436 PubMed Google Scholar
Beavo JA, Hardmann JG, Sutherland JEW (1971) Stimulation of adenosine-3′,5′-monophosphate hydrolysis by guanosine-3′,5′-monophosphate. J Biol Chem 246:3841–3846 PubMed Google Scholar
Beavo JA, Reifsnyder DH (1990) Primary sequence of cyclic nucleotide phosphodiesterase isozymes and the design of selective inhibitors. TIPS 11:150–155 PubMed Google Scholar
Bkaily G, Sperelakis N (1985) Injection of guanosine-3′,5′-cyclic monophosphate into heart cells blocks calcium slow channels. Am J Physiol 248:H745-H749 PubMed Google Scholar
Blumenthal DK, Stull JT, Gill GN (1978) Phosphorylation of cardiac troponin by guanosine-3′,5′-monophosphate-dependent protein kinase. J Biol Chem 253:334–336 Google Scholar
Bode DC, Kanter JR, Brunton LL (1991) Cellular distribution of phosphodiesterase isoforms in rat cardiac tissue. Circ Res 68:1070–1079 PubMed Google Scholar
Breitweiser GE, Szabo G (1985) Uncoupling of cardiac muscarinic and β-adrenergic receptors from ion channels by a guanine nucleotide analogue. Nature 317:538–540 PubMed Google Scholar
Büchler W, Meinecke M, Chakraborty T, Jahnsen T, Walter U, Lohmann SM (1990) Regulation of gene expression by transfected subunits of cAMP-dependent protein kinase. Eur J Biochem 188:253–259 PubMed Google Scholar
Cramb G, Banks R, Rugg EL, Aiton JF (1987) Actions of atrial natriuretic peptide (ANP) on cyclic nucleotide concentrations and phosphatidylinositol turnover in ventricular myocytes. Biochem Biophys Res Commun 148:962–970 PubMed Google Scholar
Cuppoletti J, Thakkar J, Sperelakis N, Wahler G (1989) Cardiac sarcolemmal substrate of the cGMP-dependent protein kinase. Membrane Biochemistry 7:135–142 Google Scholar
Diamond J, Ten Eick RE, Trapani AJ (1977) Are increases in cyclic GMP levels responsible for the negative inotropic effects of acetylcholine in heart? Biochem Biophys Res Comm 79:912–917 PubMed Google Scholar
DiFrancesco D, Tortora P (1991) Direct activation of cardiac pacemaker channels by intracellular cAMP. Nature 351:145–147 PubMed Google Scholar
DiFrancesco D, Tromba C (1988) Inhibition of the hyperpolarization-activated current (if) induced by acetylcholine in rabbit sino-atrial node myocytes. J Physiol 405:477–491 PubMed Google Scholar
DiFrancesco D, Tromba C (1988) Muscarinic control of the hyperpolarization-activated current (if) in rabbit sino-atrial node myocytes. J Physiol 405:493–510 PubMed Google Scholar
Eigenthaler M, Friedrich C, Schanzenbächer P, Walter U (1990) Concentration and regulation of cyclic nucleotides, vasodilator-regulated protein kinases and one of their substrates in human platelets. Eur J Clin Invest 20 (2):A16 Google Scholar
Endoh M (1979) Correlation of cyclic AMP and cyclic GMP levels with changes in contractile force of dog ventricular myocardium during cholinergic antagonism of positive inotropic actions of histamine, glucagon, theophylline and papaverine. Jap J Pharmacol 29:855–864 PubMed Google Scholar
Endoh M, Yamashita S (1981) Differential responses to carbachol, sodium nitroprusside, and 8-bromo-guanosine-3′,5′-monophosphate of canine atrial and ventricular muscle. Brit J Pharmacol 73:393–399 Google Scholar
Felbel J, Trockur B, Ecker T, Landgraf W, Hofmann F (1988) Regulation of cytosolic calcium by cAMP and cGMP in freshly isolated smooth muscle cells from bovine trachea. J Biol Chem 263:16764–16771 PubMed Google Scholar
Fischmeister R, Hartzell HC (1986) Mechanism of action of acetylcholine on calcium current in single cells from frog ventricle. J Physiol (London) 376:183–202 Google Scholar
Fischmeister R, Hartzell HC (1987) Cyclic guanosine-3′,5′-monophosphate regulates the calcium current in single cells from frog ventricle. J Physiol 387:453–472 PubMed Google Scholar
Fischmeister R, Hartzell HC (1990) Regulation of calcium current by low-Km cyclic AMP phosphodiesterases in cardiac cells. Mol Pharmacol 38:426–433 PubMed Google Scholar
Fischmeister R, Hartzell HC (1991) Cyclic AMP phosphodiesterases and Ca2+ current regulation in cardiac cells. Life Sci 48:2365–2376 PubMed Google Scholar
Fleming BP, Giles W, Lederer J (1981) Are acetylcholine-induced increases in42K efflux mediated by intracellular cyclic GMP in turtle cardiac pacemaker tissue? J Physiol 314:47–64 PubMed Google Scholar
Flitney FW, Singh J (1981) Evidence that cyclic GMP may regulate cyclic AMP metabolism in isolated frog ventricle. J Mol Cell Cardiol 13:963–979 PubMed Google Scholar
Flockerzi V, Oeken H-J, Hofmann F, Pelzer D, Cavalie A, Trautwein W (1986) Purified dihydropyridine-binding site from skeletal muscle t-tubules is a functional calcium channel. Nature 323:66–68 PubMed Google Scholar
Flockhart DA, Corbin JD (1982) Regulatory mechanisms in the control of protein kinases. CRC Crit Rev Biochem 12:133–186 PubMed Google Scholar
Furchgott RF, Vanhoutte PM (1989) Endothelium-derived relaxing and contracting factors. FASEB J 3:2007–2018 PubMed Google Scholar
George WJ, Polson JB, O'Toole AG, Goldberg N (1970) Elevation of 3′,5′-cyclic phosphate in rat heart after perfusion with acetylcholine. Proc Natl Acad Sci USA 66:398–403 PubMed Google Scholar
Gisbert MP, Fischmeister R (1988) Atrial natriuretic factor regulates the calcium current in frog isolated cardiac cells. Circ Res 62:660–667 PubMed Google Scholar
Goy MF (1991) cGMP: the wayward child of the cyclic nucleotide family. TINS 14:293–299 PubMed Google Scholar
Hartzell HC (1988) Regulation of cardiac ion channels by catecholamines, acetylcholine and 2nd messenger systems. Prog Biophys Mol Biol 52:165–247 PubMed Google Scholar
Hartzell HC, Fischmeister R (1986) Opposite effects of cyclic GMP and cyclic AMP on Ca2+ current in single heart cells. Nature 323:273–275 PubMed Google Scholar
Hartzell HC, Fischmeister R (1987) Effect of forskolin and acetylcholine on calcium current in single isolated cardiac myocytes. Mol Pharmacol 32:639–645 PubMed Google Scholar
Hartzell HC, Méry P-F, Fischmeister R, Szabo G (1991) Sympathetic regulation of cardiac calcium current is due exclusively to cAMP-dependent phosphorylation. Nature 351:573–576 PubMed Google Scholar
Hathaway DR, March KL (1989) Molecular cardiology: new avenues for the diagnosis and treatment of cardiovascular disease. J Amer Coll Cardiol 13:265–282 Google Scholar
Heil WG, Landgraf W, Hofmann F (1987) A catalytically active fragment of cGMP-dependent protein kinase. Eur J Biochem 168:117–121 PubMed Google Scholar
Hescheler J, Kameyama M, Trautwein W (1986) On the mechanism of muscarinic inhibition of the cardiac Ca current. Pflugers Arch 407:182–189 PubMed Google Scholar
Hescheler J, Tang M, Jastorff B, Trautwein W (1987) On the mechanism of histamine induced enhancement of the cardiac Ca2+ current. Pflügers Arch 410:23–29 Google Scholar
Hofmann F, Nastainczyk W, Röhrkasten A, Schneider T, Sieber M (1987) Regulation of the L-type calcium channel. Trends Pharmacol Sci 8:393–398 Google Scholar
Huggins JP, Cook EA, Piggott JR, Mattinsley TJ, England PJ (1989) Phospholamban is a good substrate for cyclic GMP-dependent protein kinase in vitro but not in intact cardiac or smooth muscle. Biochem J 260:829–835 PubMed Google Scholar
Isenberg G, Cerbai E, Klöckner UH (1987) Ionic channels and adenosine in isolated heart cells. In: Gerlach E, Becker BF (eds) Topics and perspectives in adenosine research. Springer, Berlin Heidelberg, pp 323–335 Google Scholar
Jahn H, Nastainczyk W, Röhrkasten A, Schneider T, Hofmann F (1988) Site-specific phosphorylation of the purified receptor for calcium-channel blockers by cAMP- and cGMP-dependent protein kinases, protein kinase C, calmodulin-dependent protein kinase II and casein kinase II. Eur J Biochem 178:535–542 PubMed Google Scholar
Kameyama M, Hescheler J, Hofmann F, Trautwein W (1986) Modulation of Ca current during the phosphorylation cycle in the guinea pig heart. Pflügers Arch 407:123–128 Google Scholar
Kameyama M, Hofmann F, Trautwein W (1985) On the mechanism of β-adrenergic regulation of the Ca channel in the guinea-pig heart. Pflügers Arch 405:285–293 Google Scholar
Katsuki S, Arnold WP, Murad F (1977) Effects of sodium nitroprusside, nitroglycerin and sodium azide on levels of cyclic nucleotides and mechanical activity in various tissues. J Cyclic Nucleot Res 3:239–247 Google Scholar
Kaupp UB (1991) The cyclic nucleotide-gated channels of vertebrate photoreceptors and olfactory epithelium. TINS 14:150–157 PubMed Google Scholar
Kaupp UB, Niidome T, Tanabe T, Terade S, Bönigk W, Stühmer W, Cook NJ, Kangawa K, Matsuo H, Hirose T, Miyata T, Numa S (1989) Primary structure and functional expression from complementary DNA of the rod photoreceptor cyclic GMP-gated channel. Nature 342:762–766 PubMed Google Scholar
Kohlhardt M, Haap K (1978) 8-Bromo-guanosine-3′,5′-monophosphate mimics the effect of acetylcholine on slow response action potential and contractile force in mammalian atrial myocardium. J Mol Cell Cardiol 10:573–586 PubMed Google Scholar
Lee MA, West RE jr, Moss J (1988) Atrial natriuretic factor reduces cyclic adenosine monophosphate content of human fibroblasts by enhancing phosphodiesterase activity. J Clin Invest 82:388–393 PubMed Google Scholar
Levi RC, Alloatti G (1988) Histamine modulates calcium current in guinea-pig ventricular myocytes. J Pharmacol Exp Therap 246:377–383 Google Scholar
Levi RC, Alloatti G, Fischmeister R (1989) Cyclic GMP regulates the Ca-channel current in guinea pig ventricular myocytes. Pflügers Arch 413:685–687 Google Scholar
Li T, Volpp K, Applebury BL (1990) Bovine cone photoreceptor cGMP phosphodiesterase structure deduced from a cDNA clone. Proc Natl Acad Sci USA 87:293–297 PubMed Google Scholar
Light DB, Corbin JD, Stanton BA (1990) Dual ion-channel regulation by cyclic GMP and cyclic GMP-dependent protein kinase. Nature 344:336–339 PubMed Google Scholar
Lincoln TM, Corbin JD (1978) Purified cyclic GMP-dependent protein kinase catalyzes the phosphorylation of cardiac troponin inhibitory subunit (TN-I). J Biol Chem 253:337–339 PubMed Google Scholar
Lincoln TM, Keely SL (1981) Regulation of cardiac cyclic GMP-dependent protein kinase. Biochim Biophys Acta 676:230–244 PubMed Google Scholar
Lohmann SM, Walter U, Miller PE, Greengard P, DeCamilli P (1981) Immunohistochemical localization of cyclic GMP-dependent protein kinase in mammalian brain. Proc Natl Acad Sci USA 78:653–657 PubMed Google Scholar
MacFarland RT, Zelus BD, Beavo JA (1991) High concentrations of a cGMP-stimulated phosphodiesterase mediate ANP-induced decreases in cAMP and steroidogenesis in adrenal glomerulosa cells. J Biol Chem 266:136–142 PubMed Google Scholar
Martins TJ, Mumby MC, Beavo JA (1982) Purification and characterization of a cyclic GMP-stimulated cyclic nucleotide phosphodiesterase from bovine tissues. J Biol Chem 257:1973–1979 PubMed Google Scholar
McCall D, Fried TA (1990) Effect of atriopeptin II on Ca influx, contractile behavior and cyclic nucleotide content of cultured neonatal rat myocardial cells. J Mol Cell Cardiol 22:201–212 PubMed Google Scholar
Mehegan JP, Muir WW, Unverferth DV, Ferrel RH, McGuirk SM (1985) Electrophysiological effects of cyclic GMP on canine cardiac Purkinje fibers. J Cardiovasc Pharmacol 7:30–35 PubMed Google Scholar
Méry P-F, Brechler V, Pavoine C, Pecker F, Fischmeister R (1990) Glucagon stimulates the cardiac Ca2+ current by activation of adenyl cyclase and inhibition of phosphodiesterase. Nature 345:158–161 PubMed Google Scholar
Méry P-F, Lohmann SM, Walter U, Fischmeister R (1991) Ca2+ current is regulated by cyclic GMP-dependent protein kinase in mammalian cardiac myocytes. Proc Natl Acad Sci USA 88:1197–1201 PubMed Google Scholar
Meulemans AL, Sipido KR, Sys SU, Brutsaert DL (1988) Atriopeptin III induces early relaxation of isolated mammalian papillary muscle. Circ Res 62:1171–1174 PubMed Google Scholar
Mikami A, Imoto K, Tanabe T, Niidome T, Mori Y, Takeshima H, Narumiya S, Numa S (1989) Primary structure and functional expression of the cardiac dihydropyridine-sensitive calcium channel. Nature 340:230–233 PubMed Google Scholar
Nakamura T, Gold GH (1987) A cyclic nucleotide-gated conductance in olfactory receptor cilia. Nature 325:442–444 PubMed Google Scholar
Nargeot J, Nerbonne JM, Engels L, Lester HA (1983) Time course of the increase in the myocardial slow inward current after a photochemically generated concentration jump of intracellular cAMP. Proc Natl Acad Sci USA 80:2395–2399 PubMed Google Scholar
Nawrath H (1977) Does cyclic GMP mediate the negative inotropic effect of acetylcholine in the heart? Nature 267:72–74 Google Scholar
Neyses L, Vetter H (1989) Action of atrial natriuretic peptide and angiotensin II on the myocardium: studies in isolated rat ventricular cardiomyocytes. Biochim Biophys Res Commun 163:1435–1443 Google Scholar
Nicholson CD, Challis RAJ, Shahid M (1991) Differential modulation of tissue function and therapeutic potential of selective inhibitors of cyclic nucleotide phosphodiesterase isoenzymes. TIPS 12:19–27 PubMed Google Scholar
Ono K, Trautwein W (1991) Potentiation by cyclic GMP of β-adrenergic effect on calcium current in guinea-pig ventricular cells. J Physiol (London) 443:387–404 Google Scholar
Paupardin-Tritsch D, Hammond C, Gerschenfeld HM, Nairn AC, Greengard P (1986) cGMP-dependent protein kinase enhances Ca2+ current and potentiates the serotonin-induced Ca2+ current increase in snail neurones. Nature 323:812–814 PubMed Google Scholar
Pfaffinger PJ, Martin JM, Hunter DD, Nathanson NM, Hille B (1985) GTP-binding proteins couple cardiac muscarinic receptors to a K channel. Nature 317:536–538 PubMed Google Scholar
Pfitzer G, Rüegg JC, Flockerzi V, Hofmann F (1982) cGMP-dependent protein kinase decreases calcium sensitivity of skinned cardiac fibers. FEBS Lett 149:171–175 PubMed Google Scholar
Racymaekers L, Hofmann F, Casteels R (1988) Cyclic GMP-dependent protein kinase phosphorylates phospholamban in isolated sarcoplasmic reticulum from cardiac and smooth muscle. Biochem J 252:269–273 PubMed Google Scholar
Reeves ML, Leigh BK, England PJ (1987) The identification of a new cyclic nucleotide phosphodiesterase activity in human and guinea-pig cardiac ventricle. Implications for the mechanism of action of selective phosphodiesterase inhibitors. Biochem J 241:535–541 PubMed Google Scholar
Richard S, Nerbonne JM, Nargeot J, Lester HA (1985) Photochemically produced intracellular concentration jumps of CAMP mimic the effects of catecholamines on excitation-contraction coupling in frog atrial fibers. Pflügers Arch 403:312–317 Google Scholar
Rossie S, Catterall WA (1987) Regulation of ionic channels. In: Boyer PD, Krebs EG (eds) The enzymes. Academic Press, New York, vol 58, pp 335–358 Google Scholar
Rugg EL, Aiton JF, Cramb G (1989) Atrial natriuretic peptide receptors and activation of guanylate cyclase in rat cardiac sarcolemma. Biochem Biophys Res Commun 162:1339–1345 PubMed Google Scholar
Sandberg M, Butt E, Nolte C, Fischer L, Halbrügge M, Beltman J, Jahnsen T, Genieser H-G, Jastorff B, Walter U (1991) Characterization of Sp-5,6-dichloro-1-β-D-ribofuranosylben-zimidazole-3′,5′-monophosphoro-thioate (Sp-5,6-DCl-cBIMPS) as a potent and specific activator of cAMP-dependent protein kinase in cell extracts and intact cells. Biochem J 279:521–527 PubMed Google Scholar
Sandberg M, Natarajan V, Ronander I, Kalderon D, Walter U, Lohmann SM, Jahnsen T (1989) Molecular cloning and predicted full-length amino acid sequence of the type Iβ isozyme of cGMP-dependent protein kinase from human placenta. FEBS Lett 255:321–329 PubMed Google Scholar
Schmidt K, Mayer B, Kukovetz WR (1989) Effect of calcium on endothelium-derived relaxing factor formation and cGMP levels in endothelial cells. Eur J Pharmacol 170:157–166 PubMed Google Scholar
Schulz S, Yuen PST, Garbers DL (1991) The expanding family of guanyl cyclases. TIPS 12:116–120 PubMed Google Scholar
Simmons MA, Hartzell HC (1988) Role of phosphodiesterase in regulation of calcium current in isolated cardiac myocytes. Mol Pharmacol 33:664–671 PubMed Google Scholar
Singh J, Flitney FW (1980) Adenosine depresses contractility and stimulates 3′,5′ cyclic nucleotide metabolism in the isolated frog ventricle. J Mol Cell Cardiol 12:285–297 PubMed Google Scholar
Singh J, Flitney FW (1981) Inotropic responses of the frog ventricle to dibutyryl cyclic AMP and 8-bromo-cyclic GMP and related changes in endogenous cyclic nucleotide levels. Biochem Pharmacol 30:1475–1481 PubMed Google Scholar
Szabo G, Otero AS (1990) G-Protein mediated regulation of K+ channels in heart. Ann Rev Physiol 52:293–305 Google Scholar
Takasago T, Imagawa T, Furukawa K, Ogurusu T, Shigekawa M (1991) Regulation of the cardiac ryanodine receptor by protein kinase dependent phosphorylation. J Biochem 109:163–170 PubMed Google Scholar
Tanabe T, Mikami A, Numa S, Beam KG (1990) Cardiac-type excitation-contraction coupling in dysgenic skeletal muscle injected with cardiac dihydropyridine receptor cDNA. Nature 344:451–453 PubMed Google Scholar
Tei M, Horie M, Makita S, Suzuki H, Hazama A, Okada Y, Kawai C (1990) Atrial natriuretic peptide reduces the basal level of cytosolic free Ca2+ in guinea pig cardiac myocytes. Biochem Biophys Res Comm 167:413–418 PubMed Google Scholar
Thakkar J, Tang S-B, Sperelakis N, Wahler GM (1988) Inhibition of cardiac slow action potentials by 8-bromo-cyclic GMP occurs independent of changes in cyclic AMP levels. Can J Physiol Pharmacol 66:1092–1095 PubMed Google Scholar
Trautwein W, Taniguchi J, Noma A (1982) The effect of intracellular cyclic nucleotides and calcium on the action potential and acetylcholine response of isolated cardiac cells. Pflügers Arch 392:307–314 Google Scholar
Trautwein W, Trube G (1976) Negative isotropic effect of cyclic GMP in cardiac fiber fragments. Pflügers Arch 366:293–295 Google Scholar
Tsien RW, Bean BP, Hess P, Lansman JB, Bilius B, Nowycky M (1986) Mechanisms of calcium channel modulation by β-adrenergic agents and dihydropyridine calcium agonists. J Mol Cell Cardiol 18:691–710 PubMed Google Scholar
Tuganowski W, Kopee P (1978) The effect of cGMP in rabbit auricle as studied by a cut-end method. Naunyn-Schmied Arch Pharmacol 304:211–213 Google Scholar
Volpe M, Sosa RE, Müller FB, Camargo MJF, Glorioso N, Laragh JH, Maack T, Atlas SA (1986) Differing hemodynamic responses to atrial natriuretic factor in two models of hypertension. Am J Physiol 250:H871-H878 PubMed Google Scholar
Wahler GM, Rusch NJ, Sperelakis N (1990) 8-Bromo-cyclic GMP inhibits the calcium channel current in embryonic chick ventricular myocytes. Can J Physiol 68:531–534 Google Scholar
Wahler GM, Sperelakis N (1985) Intracellular injection of cyclic GMP depresses cardiac slow action potentials. J Cyclic Nucleot Prot Phosphoryl Res 10:83–95 Google Scholar
Waldman SA, Murad F (1987) Cyclic GMP synthesis and function. Pharmacol Rev 39:163–196 PubMed Google Scholar
Waldmann R, Walter U (1989) Cyclic nucleotide elevating vasodilators inhibit platelet aggregation at an early step of the activation cascade. Eur J Pharmacol 159:317–320 PubMed Google Scholar
Walter U (1984) Cyclic GMP-regulated enzymes and their possible physiological functions. Adv Cycl Nucl Prot Phosph Res 17:249–258 Google Scholar
Walter U (1989) Physiological role of cGMP and cGMP-dependent protein kinase in the cardiovascular system. Rev Physiol Biochem Pharmacol 113:42–88 Google Scholar
Walter U, Nolte C, Geiger J, Schanzenbächer P, Kochsiek K (1991) Inhibition of platelet function by cyclic nucleotides and cyclic nucleotide-dependent protein kinases. In: Herman AG (ed) Antithrombotics: pathophysiological rationale for pharmacological interventions. Kluwer Academic Publishers, Netherlands, pp 121–138 Google Scholar
Weishaar RE, Kobylarz-Singer DC, Steffen RP, Kaplan HR (1987) Subclasses of cyclic AMP-specific phosphodiesterase in left ventricular muscle and their involvement in regulating myocardial contractility. Circ Res 61:539–547 PubMed Google Scholar
Wernet W, Flockerzi V, Hofmann F (1989) The cDNA of the two isoforms of bovine cGMP-dependent protein kinase. FEBS Lett 251:191–196 PubMed Google Scholar
Whalin ME, Scammel JG, Strada SJ, Thompson WJ (1991) Phosphodiesterase II, the cGMP-activable cyclic nucleotide phosphodiesterase, regulates cyclic AMP metabolism in PC12 cells. Mol Pharmacol 39:711–717 PubMed Google Scholar
Wilkerson RD, Paddock RJ, George WJ (1976) Effects of derivatives of cyclic AMP and cyclic GMP on contraction force of cat papillary muscles. Eur J Pharmacol 36:247–251 PubMed Google Scholar
Wrenn RW, Kuo JF (1981) Cyclic GMP-dependent phosphorylation of an endogenous protein from rat heart. Biochem Biophys Res Commun 101:1274–1280 PubMed Google Scholar