Selective emergence and survival of early polypeptides in water (original) (raw)
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The emergence of oligopeptides, which are crucial for the development of primitive cells, necessitates selective pathways rather than random prebiotic chemistry to achieve their formation. This study provides experimental evidence for the selective condensation of amino acids in water through N-carboxyanhydrides, demonstrating that such processes can lead to the enrichment of proteinaceous amino acids and the formation of stable homochiral sequences, thereby contributing to our understanding of the origins of life.
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References
- Oro, J.: 1963,Ann. N.Y. Acad. Sci. 108, 464–481.
CAS PubMed Google Scholar - Lemmon, R. M.: 1970,Chem. Revs. 70, 95–109.
Article CAS Google Scholar - Fox, S. W. and Dose, K.: 1977, Molecular evolution and the origin of life, Marcel Dekker Inc., pp. 69–100.
- Weber, A. L. and Miller, S. L.: 1981,J. Mol. Evol. 17, 273–284.
CAS PubMed Google Scholar - Cronin, J. R. and Pizzarello, S.: 1983,Adv. Space Res. 3, 5–18.
CAS PubMed Google Scholar - Hay, R. W. and Main, L.: 1968,Aust. J. Chem. 21, 155–169.
CAS Google Scholar - Brack, A.: 1982,BioSystems 15, 201–207.
Article CAS PubMed Google Scholar - Paecht-Horowitz, M., Berger, J., and Katchalsky, A.: 1970,Nature 228, 636–639.
Article CAS PubMed Google Scholar - Armstrong, D. W., Seguin, R., McNeal, C. J., Mac Farlane, R. D., and Fendler, J. H.: 1978,J. Amer. Chem. Soc. 100, 4605–4606.
CAS Google Scholar - Weber, A. L. and Orgel, L. E.: 1979,J. Mol. Evol. 13, 193–202.
CAS PubMed Google Scholar - Hirschmann, R., Strachan, R. G., Schwam, H., Schoenewaldt, E. F., Joshua, H., Barkemeyer, B., Veber, D. F., Paleveda, W. J., Jacob, T. A., Beesley, T. E., and Denkewalter, R. G.: 1967,J. Org. Chem. 32, 3415–3425.
Article CAS PubMed Google Scholar - Staab, H. A.: 1959,Angew. Chem. 71, 194–195.
CAS Google Scholar - Korshak, V. V., Poroshin, K. T., and Kozarenko, T. D.: 1954,Izv. Akad. Nauk SSSR, Otdel Khim. Nauk 663–669.
- Kozarenko, T. D., Poroshin, K. T., and Khurgin, Yu. I.: 1957,Izv. Akad. Nauk SSSR, Otdel Khim. Nauk 640–642.
- Ehler, K. W. and Orgel, L. E.: 1976,Biochim. Biophys. Acta 434, 233–243.
CAS PubMed Google Scholar - Brack, A.: 1984,Origins of Life 14, 229–236.
Article CAS Google Scholar - Brack, A. and Orgel, L. E.: 1975,Nature 256, 383–387.
Article CAS PubMed Google Scholar - Brack, A. and Caille, A.: 1978,Int. J. Peptide Protein Res. 11, 128–139.
CAS Google Scholar - Brack, A. and Spach, G.: 1981,Origin of Life, D. Reidel Publ. Co., Dordrecht, Holland, pp. 487–493.
Google Scholar - Barbier, B., Caille, A., and Brack, A.: 1984,Biopolymers 23, 2299–2310.
Article CAS PubMed Google Scholar - Brack, A. and Trudelle, Y.: 1985,Polymer Comm. 26, 369–370.
CAS Google Scholar - Brack, A. and Spach, G.: 1980,J. Mol. Evol. 15, 231–238.
Article CAS PubMed Google Scholar - Spach, G. and Brack, A.: 1979,J. Mol. Evol. 13, 47–56.
Article CAS PubMed Google Scholar - Pace, N. R. and Marsh, T. L.: 1985,Origins of Life 16, 97–116.
CAS PubMed Google Scholar - Zaug, A. J. and Cech, T. R.: 1986,Science 231, 470–475.
CAS PubMed Google Scholar - Barbier, B. and Brack, A.: 1987,Origins of Life (this volume).