Birth defects surveillance study (original) (raw)

Abstract

Objective: To study the overall frequency of congenital malformations in a city hospital in the first three days of life.Methods: 17,653 consecutive newborns were examined and diagnosed at a maternity hospital by pediatricians and geneticists. Relevant information was documented on a predesigned proforma and analyzed.Results: Of the 17,653 births 294 (1; 6%) had major malformations and 1400 (7.92%) had minor malformations. Amongst 17,653 births 328 (1.8%) were stillbirths. Malformations were highest in this group. Polygenic traits accounted for 45.1% while chromosomal etiology was found in 4%. A genetic basis was found in 65.4% of cases.Conclusion: With emphasis on “small family” norms & population control it is necessary to identify malformations so that Interventional programmes can be planned

Access this article

Log in via an institution

Subscribe and save

• Starting from 10 chapters or articles per month
• Access and download chapters and articles from more than 300k books and 2,500 journals
• Cancel anytime View plans

Buy Now

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

1. A national Collaborative Study of identification of High Risk Families, Mothers and Outcome of their offsprings with particular reference to the problem of maternal nutrition, low birth weight, perintal and infant morbidity in rural and urban slum communities. Indian Council of Medical Research, New Delhi, 1990 : 119–126.
2. Singh M. Hospital based data on perinatal and neonatal mortality in India.Indian Pediatr 1986; 23: 579–584.
   PubMed CAS Google Scholar
3. Mishra PC, Baveja R. Congenital malformations in the newborn — A prospective study,Indian Pediatr 1989; 26: 32–35.
   PubMed CAS Google Scholar
4. Verma M, Chaatwal J, Singh D. Congenital malformations — A retrospective study of 10,000 cases.Indian J Pediatr 1991; 58: 259–263.
   PubMed Google Scholar
5. Mathur BC, Karan WS, Vijayadevi KK. Congenital malformations in newborn.Indian Pediatr 1975; 12: 179–183.
   PubMed CAS Google Scholar
6. Sugunbai NS, Mary M, Shamalan K, Nair PM. An etological study of congenital malformations in newborns.Indian Pediatr 1982; 19: 1003–1009.
   Google Scholar
7. Kulshrestha R, Nath LM, Upadhyaya P. Congenital malformations in liveborn infants in a rural community.Indian Pediatr 1983; 20: 45–49.
   PubMed CAS Google Scholar
8. Aiyar RR, Agarwal JR. Observation on newborn. A study of 10,000 consecutive livebirths.Indian Pediatr 1969; 729–742.
9. Martinez-Frias ML, Bermejo E, Frias JL. Analysis of Deformations in 26,810 Consecutive Infants with Congenital Defects.Am J Med Genet 1999; 84: 365–368.s Available
   Article PubMed CAS Google Scholar

Download references

Author information

Author notes

1. R. A. Adhia
   Present address: Genetic Research Centre, National Institute for Research in Reproductive Health, Parel, Mumbai, India

Authors and Affiliations

1. Genetic Research Centre, National Institute for Research in Reproductive Health, Parel, Mumbai, India
   Z. M. Patel

Authors

1. Z. M. Patel
2. R. A. Adhia

Corresponding author

Correspondence toZ. M. Patel.

Rights and permissions

About this article

Cite this article

Patel, Z.M., Adhia, R.A. Birth defects surveillance study.Indian J Pediatr 72, 489–491 (2005). https://doi.org/10.1007/BF02724426

Download citation

• Issue date: June 2005
• DOI: https://doi.org/10.1007/BF02724426

Key words