Molecular biology of inhibitory amino acid receptors (original) (raw)
Anfinsen C. B. (1973) Principles that govern the folding of protein chains.Science181, 223–230. ArticlePubMedCAS Google Scholar
Edelhoch H. and Osborne J. (1976) The thermodynamic stability of proteins, nucleic acids and membranes.Advances in Protein Chemistry30, 183–250. ArticlePubMedCAS Google Scholar
Eisenberg D. (1984) Three dimensional structure of membrane and surface proteins.Ann Rev. Biochem.53, 595–623. ArticlePubMedCAS Google Scholar
Rossman M. and Arogs P. (1981) Protein folding.Ann. Rev. Biochem.50, 497–532. Article Google Scholar
Takahashi H., Tanabe T., Toyosato M., Kikyotani S., Furutani Y., Hirose T., Takashima H., Inayama S., Miyata T., and Numa S. (1982), Structural homology of_Torpedo californica_ acetylcholine receptor subunits_Nature_ 302, 528–532. Google Scholar
Noda M., Shimizu S., Tanabe T., Takai T., Kayano T., Ikeda T., Takahashi H., Nakayama H., Kanaoka Y., Minamino N., Kangawa K., Mtsuo H., Raftery M. A., Hirose T., Inayama S., Hayashida H., Miyata T., and Numa S. (1984) Primary structure of_Electrophorus electricus_ sodium channel deduced from cDNA sequences.Nature312, 121–127. ArticlePubMedCAS Google Scholar
Jencks W. P. (1987) Binding energy, specificity and enzymatic catalysis: the circe effect.Adv. Enzymology43, 219–310. Article Google Scholar
Chang H. W., Bock E., and Neumann E. (1984) Long-lived metastable states and hysteresis in the binding of acetylcholine to_Torpedo californica_ acetylcholine receptor.Biochemistry23, 4546–4556. ArticlePubMedCAS Google Scholar
Tallman J. F. and Gallager D. W. (1985) The GABA-ergic system: A locus of benzodiazepine action.Ann. Rev. Neurosci.8, 21–44. ArticlePubMedCAS Google Scholar
Haefly W., Kyburz E., Gerecke M., and Mohler H. (1985), Recent advances in the molecular pharmacology of benzodiazepine receptors and in the structure activity relations of their agonists and antagonists, in_Advances in Drug Research_,14, pp. 165–322, Testa B., ed.) Academic, London. Google Scholar
Olsen R. and Venter C. (eds.) (1986)Benzodiazepine/GABA Receptors and Chloride Channels: Structural and Functional Properties, Alan Liss, New York, NY. Google Scholar
Enna S. (ed.) (1983)The GABA Receptors. Humana, Clifton, NJ. Google Scholar
Aprison M. H., Davidoff R. A., and Werman R. (1970) Glycine: its metabolic and possible neurotransmitter roles in nervous tissue, in_Handbook of Neurochemistry_,3 (A. Lajtha, ed.) Plenum, New York, NY. Google Scholar
Bowery N. G., Hill D. R., Hudson A. O., Doble A., Middlemiss D. N., Shoe J., and Turnbull M. J. (1980) (-) Baclofen decreases neurotransmitter release in the mammalian CNS by an action at a novel GABA receptor.Nature283, 92–94. ArticlePubMedCAS Google Scholar
Karbon E. W., Duman R. S., and Enna S. J. (1984) GABA receptors and norepinephrine-stimulated cAMP production in rat brain cortex.Brain Res.306, 327–332. ArticlePubMedCAS Google Scholar
Yarowsky P. J. and Carpenter D. O. (1978) Receptors for gamma-aminobutyric acid (GABA) on_Aplysia neurons_.Brain Res.144, 75–94. ArticlePubMedCAS Google Scholar
Enna S. J. and Snyder S. H. (1975) Properties of gamma-aminobutyric acid (GABA) receptor binding on rat brain synaptic membrane fractions.Brain Res.100, 81–97. ArticlePubMedCAS Google Scholar
Enna S. J., and Snyder S. H. (1977) Influences of ions, enzymes, and detergents on gamma-aminobutyric acid-receptor binding in synaptic membranes of rat brain.Mol. Pharmacol.13, 442–453. PubMedCAS Google Scholar
Enna S. J., Collins J. F., and Snyder S. H. (1977) Stereospecificity and structure activity requirements of GABA receptor binding in rat brain.Brain Res.124, 185–190. ArticlePubMedCAS Google Scholar
Mohler H. and Okada T. (1977) Properties of gamma-aminobutyric acid receptor binding with (+)-3H-bicuculline methiodide in rat CNS.Nature267, 65–67. ArticlePubMedCAS Google Scholar
Olsen R. W. and Snowman A. M. (1983)3H-bicuculline methochloride binding to low-affinity gamma-aminobutyric acid receptor sites.J. Neurochem.41, 1653–1663. ArticlePubMedCAS Google Scholar
Browner M., Ferkany J. W., and Enna S. J. (1981) Biochemical identification of pharmacologically and functionally distinct GABA receptors in rat brain.J. Neurosci.1, 514–518. PubMedCAS Google Scholar
Gallager D. W., Rauch S., and Malcolm A. (1984) Alterations in a low affinity GABA recognition site following chronic benzodiazepine.Eur. J. Pharmacol.98, 159–160. ArticlePubMedCAS Google Scholar
Krogsgaard-Larsen P. (1981) Gamma-aminobutyric acid agonists, antagonists and uptake inhibitors. Design and therapeutic effects.J. Med. Chem.24, 1377–1383. ArticlePubMedCAS Google Scholar
Falch E., Jacobsen P., Krogsgaard-Larsen P. and Curtis D. (1985) GABA-mimetic activity and effects on diazepam binding of amino-sulphonic acids structurally related to piperidine-4-sulphonic acid.J. Neurochem.44, 68–75. ArticlePubMedCAS Google Scholar
Krogsgaard-Larsen P., Hjeds H., Curtis D., Lodge D., and Johnston G. A. R. (1979) Dihydromuscimol, thiomuscimol and related heterocyclic compounds as GABA analogues.J. Neurochem.32, 1717–1724. ArticlePubMedCAS Google Scholar
Braestrup C., Nielsen M., Krogsgaard-Larsen P. and Falch E. (1979) Partial agonist for the brain GABA-benzodiazepine receptor complex.Nature280, 331–333. ArticlePubMedCAS Google Scholar
Squires R. (1984) Benzodiazepine receptors, in,Handbook of Neurochemistry (Lajtha A., ed.) pp. 261–307, Plenum, New York, NY. Google Scholar
Clinthorne J., Cisin I., Bolter M., Mellinger G., and Ulenhulth E. (1986) Changes in popular attitudes and beliefs about tranquilizers.Arch. Gen. Psychiat.43, 527–532. PubMedCAS Google Scholar
Usdin, E., Skolnick P., Tallman J. F., Greenblatt D., and Paul S. (eds.) (1982) Pharmacology of Benzodiazepines, MacMillan, London. Google Scholar
Tallman J. F., Paul S., Skolnick P., and Gallager D. W. (1980) Receptors for the age of anxiety: pharmacology of benzodiazepines.Science207, 274–281. ArticlePubMedCAS Google Scholar
Haefly W., Pieri L., Polc P., and Schaffner R. (1981) General pharmacology and neuropharmacology of benzodiazepine derivatives.Handbook Exptl. Pharmacol.55, 1–82. Google Scholar
Squires R. and Braestrup C. (1977) Benzodiazepine receptors in rat brain.Nature,166, 732–734. Article Google Scholar
Mohler H. and Okada T. (1977) Benzodiazepine receptors in rat brain.Nature,166, 732–734. Google Scholar
Tallman J. F., Thomas J. W., and Gallager D. W. (1978) GABA-ergic modulation in benzodiazepine binding site sensitivity.Nature274, 383–385. ArticlePubMedCAS Google Scholar
Gallager D., Lakoski J., Gonsalves S., and Rauch S. (1984) Chronic benzodiazepine treatment decreases postsynaptic GABA sensitivity.Nature308, 74–77. ArticlePubMedCAS Google Scholar
Nielsen M., Gredal O., and Braestrup C. (1979) Some properties of 3H-diazepam-displacing activity from human urine.Life Sci.25, 679–686. ArticlePubMedCAS Google Scholar
Braestrup C., Nielson, M., and Olsen C. E. (1980) Urinary and brain beta-carboline-3-carboxylates as potent inhibitor of brain benzodiazepine receptors.Proc. Natl. Acad. Sci. USA77, 2288–2292. ArticlePubMedCAS Google Scholar
Tenen H. S. and Hirsch J. D. (1980) Beta-carboline-3-carboxylic acid ethyl ester antagonises diazepam activity.Nature288, 609–610. ArticlePubMedCAS Google Scholar
Braestrup C. and Nielsen M. (1983) Benzodiazepine receptors, in Handbook:Psychopharmacology17, 285–384. CAS Google Scholar
Hunkeler W., Mohler H., Pieri L., Polc P., Bonetti E., Cumin R., Schaffner R., and Haefly W. (1981) Selective antagonists of benzodiazepines.Nature290, 514–516. ArticlePubMedCAS Google Scholar
Mohler H. and Richard J. C. (1981) Agonist and antagonist benzodiazepine receptor interactions.Nature294, 763–765. ArticlePubMedCAS Google Scholar
Mohler H., Burkard, W., Keller H. H., Richards J., and Haefely W. (1981) Benzodiazepine receptor antagonist Ro 15-1788: Binding characteristics and interaction with drug-induced changes in dopamine turnover and cerebellar cGMP levels.J. Neurochem.37, 714–722. ArticlePubMedCAS Google Scholar
Gallager D. W., Heninger K., and Heninger G. K. (1986) Periodic benzodiazepine antagonist administration prevents benzodiazepine with-drawal symptoms in primates.Eur. J. Pharmacol.132, 31–38. ArticlePubMedCAS Google Scholar
Costa E. and Guidotti (1985) Endogenous lingands for benzodiazepine recognition sites.Biochem. Pharmacol.34, 3399–3403. ArticlePubMedCAS Google Scholar
Gray P., Glaister D., Seeburg P., Guidotti A., and Costa E. (1986) Cloning and expression of cDNA for human diazepam binding inhibitor, a natural ligand of an allosteric regulatory site of the γ-aminobutyric acid type A receptor.Proc. Nat. Acad. Sci. USA83, 7547–7551. ArticlePubMedCAS Google Scholar
Marquardt H., Todaro G., and Shoyab M. (1986) Complete amino acid sequences of bovine and human bendozepines.J. Biol. Chem.261, 9727–9731. PubMedCAS Google Scholar
Mocchetti I., Einstein R., and Brosins J. (1986) Putative diazepam binding inhibitor peptide: cDNA clones from rat.Proc. Nat. Acad. Sci. USA83, 7221–7225. ArticlePubMedCAS Google Scholar
Fedan J., Hogaboom G. K., and O'Donnell J. P. (1984) Photoaffinity labels as pharmacological tools.Biochem. Pharmacol.33, 1167–1180. ArticlePubMedCAS Google Scholar
Rice K., Brossi A., Tallman J., Paul S., and Skolnick P. (1979) Irazepine, a noncompetitive, irreversible inhibitor of diazepam binding to benzodiazepine receptors.Nature278, 854–855. ArticlePubMedCAS Google Scholar
Williams E. F., Rice K., Paul S., and Skolnick P. (1980) Heterogeneity of benzodiazepine receptors in the CNS demonstrated with Kenazepine, an alkaylating benzodiazepine.J. Neurochem.35, 591–597. ArticlePubMedCAS Google Scholar
Skolnick P., Schweri M., Kutter E., Williams E., and Paul L. S. (1982) Inhibition of diazepam and beta-carboline binding by irazepine: Evidence for multiple domains of the benzodiazepine receptor.J. Neurochem.39, 1142–1144. ArticlePubMedCAS Google Scholar
Sternbach L. H. (1983) The discovery of CNS active 1,4-benzodiazepines (chemistry) in_The Pharmacology of Benzodiazepines_ (Usdin E., Skolnick P., Tallman J., Greenblatt D., and Paul S., eds.), London, Macmillan pp. 7–14. Google Scholar
Mohler H., Battersby M. K., and Richards J. G. (1980) Benzodiazepine receptor protein identified and visualized in brain tissue by a photoaffinity label.Proc. Nat. Acad. Sci. USA77, 1161–1670. Article Google Scholar
Thomas J. W. and Tallman J. F. (1981) Characterizations of photoaffinity labeling of benzodiazepine binding sites.J. Biol. Chem.156, 9838–9842. Google Scholar
Young W. S. and Kuhar M. J. (1980) Radiohistochemical localization of benzodiazepine receptors in rat brain.J. Pharmacol. Exp. Ther.212, 337–346. PubMedCAS Google Scholar
Young W. S., Niehoff D., Kuhar M. J., Beer B., and Lippa A. S. (1981) Multiple benzodiazepine receptor localization by light microscopic radiohistochemistry.J. Pharmacol. Exp. Ther.221, 670–675. Google Scholar
Niehoff D. L., Marshall R. D., Horst W. D., O'Brien R. A., Palacios J. M., and Kuhar M. J. (1982) Binding of a radiolabeled triazolopyridazine to a subtype of benzodiazepine receptor in the rat cerebellum.J. Pharmacol. Exp. Ther.221, 670–675. PubMedCAS Google Scholar
Mohler H., Richard J. G., and Wu J. Y. (1981) Autoradiographic localization of benzodiazepine receptors in immunocytochemically identified gamma-aminobutyergic synapses.Proc. Natl. Acad. Sci. USA78, 1935–1938. ArticlePubMedCAS Google Scholar
Sieghart W. and Karobath M. (1980) Molecular heterogeneity of benzodiazepine receptors.Nature282, 285–287. Article Google Scholar
Sieghart W., Mayer A., and Drexler G. (1985) Properties of flunitrazepam binding to different benodiazepine binding proteins.Eur. J. Pharmacol.88, 291–299. Article Google Scholar
Eichinger A. and Sieghart W. (1986) Postnatal development of protein associated with benzodiazepine receptors.J. Neurochem.46, 173–180. ArticlePubMedCAS Google Scholar
Klotz K., Bocchetta A., Neale J., Thomas J. W., and Tallman J. F. (1984) Proteolytic degradation of neuronal benzodiazepine binding sites.Life Sci.34, 293–299. ArticlePubMedCAS Google Scholar
Mallorga P., Hamburg M., Tallman J. F., and Gallager D. W. (1980) Changes in GABA modulation of brain benzodiazepine binding.Neuropharmacology19, 405–408. ArticlePubMedCAS Google Scholar
Squires R. F., Benson D. I., Braestrup C., Coupet J., Klepner C. A., Myers V., and Beer B. (1979) Some properties of brain specific benzodiazepine receptors: New evidence for multiple receptors.Pharmacol. Biochem. Behav.10, 825–830. ArticlePubMedCAS Google Scholar
Klepner C. A., Lippa A. S., Benson D. I., Sano M. C., and Beer B. (1979) Resolution of two biochemically and pharmacologically distinct benzodiazepine receptors.Pharmacol. Biochem. Behav.11, 457–462. ArticlePubMedCAS Google Scholar
Lippa A. S., Coupet J., Greenblatt E. N., Klepner C. A., and Beer B. (1979) Synthetic, nonbenzodiazepine ligand for benzodiazepine receptors: A probe for investigating neuronal substrates of anxiety.Pharmacol. Biochem. Behav.11, 99–106. ArticlePubMedCAS Google Scholar
Melchior C. L., Garrett K., and Tabakoff B. (1983) Proconvulsant effects of the benzodiazepine agonist CL 218, 872_Soc. Neurosci. Abstr._ 9, 129. Google Scholar
Braestrup C., Schmiechen R., Neet G., Nielsen M., and Petersen E. N. (1982) Interaction of convulsive ligands with benzodiazepine receptors.Science216, 1241–1243. ArticlePubMedCAS Google Scholar
Thomas J. W. and Tallman J. F. (1983) Photoaffinity labeling of benzodiazepine receptors causes altered agonist-antagonist interactions.J. Neurosci.3, 433–440. PubMedCAS Google Scholar
Gee K. W., Morelli M., and Yamamura H. I. The effect of temperature on CL218, 872 and propyl beta-carboline-3-carboxylate inhibition of3H-flunitrazepam binding in rat brain.Biochem. Biophys. Res. Commun.105 (4), 1532–1537
Thomas J. and Tallman J. F. Solubilization and characterization of brain benzodiazepine binding sites, in,Brain Neurotransmitter and Neuro Modulator Receptor Methodology, pp. 95–112, Academic, New York, NY.
Mohler H. (1982) Benzodiazepine receptors: Differential interaction of benzodiazepine agonists and antagonists after photoaffinity labeling with flunitrazepam.Eur. J. Pharmacol.80, 435–436. ArticlePubMedCAS Google Scholar
Kanazawa H. and Futari M. (1982) Structure and function of H+-ATPase: What have we learned form_E. Coli_ H+-ATPase.NY Acad. Sci.142, 45–64. Article Google Scholar
Costa T., Rodbard D., and Pert C. B. (1979) Is the benzodiazepine receptor coupled to a chloride anion channel?Nature177, 315–317. Article Google Scholar
Ticku M. and Maksay G. (1983) Convulsant/depressant site of action at the allosteric benzodiazepine-GABA receptorionophore complex.Life Sci.33, 2363–2375. ArticlePubMedCAS Google Scholar
Olsen R. W. (1982) Drug interactions at the GABA receptor-ionophore complex_Ann. Rev. Pharmacol. Toxicol._ 22, 245–277. ArticleCAS Google Scholar
Leeb-Lundberg F., Snowman A., and Olsen R. (1980) Barbiturate receptor sites are coupled to benzodiazepine receptors.Proc. Nat. Acad. Sci. USA77, 7468–7472. ArticlePubMedCAS Google Scholar
Squires R. F., Casida J., Richardson M., and Saederup E. (1983)25S-t_-butylbicyclophosphorothionate binds with high affinity to specific sites coupled to GABA-A and ion recognition sites_Mol. Pharmacol.23, 326–336. PubMedCAS Google Scholar
Klunk W., Kalman B., Ferrendelli J., and Covey D. (1983) Computer-assisted modeling of the picrotoxinin and gamma-butyrolactone receptor site.Mol. Pharmacol.23, 511–518. PubMedCAS Google Scholar
Buch H. P., Schneider-Affeld F., Rummel W., and Knabe J. (1973) Stereochemical dependence of pharmacological activity in a series of optically active_n_-methylated barbiturates.Arch. Pharmacol.277, 191–198. ArticleCAS Google Scholar
Mathers D. and Barker J. (1982) Chemicallly induced channels in nerve cell membranes.Int. Rev. of Neurobiol.23, 1–34. ArticleCAS Google Scholar
Barker J. and Mathers D. (1981) GABA analogues activate on channels of different duration on cultured mouse spinal neurons.Science2312, 358–361. Article Google Scholar
Study R. and Barker J. (1981) Diazepam and (-)pentobarbital fluctuation analysis reveals different mechanism for potentiation of GABA responses in cultured central neuons.Proc. Natl. Acad. Sci. USA78, 7180–7184. ArticlePubMedCAS Google Scholar
Choi D., Farb D., and Fischbach G. (1981) Chlordaizepoxide selectively potentiates GABA conductance of spinal cord and sensory neurons in cell culture.J. Neurophysiol.45, 621–631. PubMedCAS Google Scholar
Hamill D. P., Bormann J., and Sakmann B. (1983) Activation of multiple conductance state channels in spinal neurones by glycine and GABA.Nature305, 805–808. ArticlePubMedCAS Google Scholar
Borman J. and Clapham D. (1985) Gamma-amminobutyric acid receptor channels in adrenal chromaffin cells: A patch clamp study.Proc. Nat. Acad. Sci. USA82, 2168–2172. Article Google Scholar
Sakmann B., Hamill O., and Borman G. (1983) Patch clamp measurements of elementary chloride currents activated by the putative inhibitory transmitters GABA and glycine in mammalian spinal neurons.J. Neural Trans.18, 83–95. CAS Google Scholar
Thampy K. G. and Barnes E. M., Jr. (1984) γ-Aminobutyric acid-gated chloride in cultured cerebral neurons.J. Biol. Chem.249, 1753–1757. Google Scholar
Wong E. H. F., Leeb-Lundberg L. M. F., Teichberg V. I., and Olsen R. W. (1984), γ-Aminobutyric acid activation of36CL-flux in rat hippocampal slices and its potentiation by harbiturates.Bain Res.303, 267–275. ArticleCAS Google Scholar
Schwartz R. D., Jackson J. A., Weigert D., Skolnick P., and Paul S. M. (1985) Characterization of barbiturate-stimulated chloride efflux from rat brain synaptoneurosomes.J. Neurosci.5, 2963–2970. PubMedCAS Google Scholar
Schwartz R. D., Suzdak P. D., and Paul S. M., (1986) γ-Aminobutyric acid (GABA) and barbiturate-mediated36CI-uptake in rat brain synaptoneurosome: Evidence for rapid desensitation of the GABA receptor-coupled chloride ion channel.Mol. Pharmacol.30, 419–426. PubMedCAS Google Scholar
Obata T., Palmer C. J., Casida J. E., Laird H., and Yamamura H. I. Benzodiazepine, barbiturate, and cage convulsant modulation of GABA-stimulated chloride (36CL-) uptake in membrane vesicles from rat cerebral cortex.Neurosi. Abst.12, 670.
Neubig R. R., Boyd N. D., and Cohen J. B. (1982) Conformations of_Torpedo_ acetycholine receptor associated with ion transport and desensitization.Biochemistry21, 3460–3467. ArticlePubMedCAS Google Scholar
Yousufi M. A. K., Thomas J. W., and Tallman J. F. (1979) Solubilization of benzodiazepine binding site form rat cortex.Life Sci.25, 463–470. ArticleCAS Google Scholar
Gavish M., Chang R. S. L., and Snyder S. H. (1979) Solubilization of histamine H-1, GABA, and benzodiazepine receptors.Life Sci.25, 783–790. ArticlePubMedCAS Google Scholar
Stephenson F. A. and Olsen R. W. (1982) Solubilization by CHAPS detergents of barbiturate-enhanced benzodiazepine-GABA receptor complex.J. Neurochem.39, 1579–1586. ArticlePubMedCAS Google Scholar
Sigel. E, Stephenson A., Mamalaki D., and Barnard E. A gamma-amino butyric acid benzodiazepine receptor complex of bovine cerebral cortex.J. Biol. Chem.258, 6965–6971.
Sigel E. and Barnard E. A Gamma-amirbutyric acid/benzodiazepine complex from bovine cerebral cortex: Improved purification with preservation of regulatory sites and their interaction.J. Biol. Chem.259, 7219–7223.
Schoch P., Haring P., Takacs B., Stabii C., and Mohler H. (1984) A GABA/benzodiazepine receptor complex from bovine brain: purification, reconstitution and immunological characterization.J. Receptor Res.4, 189–200. CAS Google Scholar
Nielsen M., Honore T., an Braestrup C. (1985) Radiation inactivation of brain35S-_t_-butyl bicyclophosphorothionate binding sites reveals complicated molecular arrangements of the GABA/benzodiazepine receptor chloride channel complex.Biochem. Pharmacol.34, 3633–3642 ArticlePubMedCAS Google Scholar
Schoch P., Richards J. G., Haring P., Takacs B., Stahli C., Staehelin T., Haefly W., and Mohler H. (1985) Colocalization of GABA alpha receptors and benzodiazepine receptors in the brain shown by monoclonal antibodies.Nature314, 168–171. ArticlePubMedCAS Google Scholar
Haring P., Stahli C., Schock P., Takas B., Staehelin T., and Mohler H. (1985) Monoclonal antibodies reveal structural homogeneity of gamma-aminobutyricacid/benzodiazepine receptors in different brain areas.Proc. Natl. Acad. Sci. USA82, 4837–4841. ArticlePubMedCAS Google Scholar
Stephenson F. A., Casalotti S., Mamalaki C. and Barnard E. (1986) Antibodies recognizing the GABA alpha/benzodiazepine receptor including its regulatory site.J. Neurochem.46, 854–861. ArticlePubMedCAS Google Scholar
Sweetnam P., Gallombardo P., and Tallman J. F. (1986) Molecular aspects of benzodiazepine receptor function.Psychopharmacol. Bull.22, 641–645. PubMedCAS Google Scholar
Gallombardo P., Sweetnam P. M., and Tallman J. F. Preparation of monoclonal antibodies with antibenzodiazepine binding site specificity (submitted).
Sweetnam P., Nestler E., Gallombardo P., Brown S., Duman R., Bracha H. S., and Tallman J. E. (1986) Comparison of the molecular structure of GABA/benzodiazepine receptors purified from rat and human cerebellum.Soc. Neurosci. Abst.12, 665. M Google Scholar
Sweetnam P. and Tallman J. F. (1986) Regional differences in brain benzodiazepine receptor carbohydrates.Mol. pharmacol.29, 299–306. PubMedCAS Google Scholar
Barker J. L., Harrison N. L., and Mariani A. P. (1986) Benzodiazepine pharmacology of cultured mammalian CNS neurons.Life Sci.39, 1959–1968. ArticlePubMedCAS Google Scholar
Richard J. G., Schoch P., and Mohler H. (1985) Monoclonal antbodies to a GABA/benzodiazepine receptor complex: High resolution mapping in rat and human brain.Neurosci. Abst. 1120.
Deutch A., Sweetnam P., Gallombardo P., Goldstein M., Fuxe K., Bird E., Stevens T., Tallman J., and Roth R. H. (1986) Alterations in GABA/benzodiazepine receptors in the substantia nigra of Parksinson's and Huntington's disease patients. Presented at_Annual Meeting of American College of Neuropsychopharmacology_.
Houamed K., Bilbe G., Smart T., Constanti A., Bronen D., Barnard E., and Richards B. (1984) Expression of functional GABA, glycine and glutamate receptors in_Xenopus_ oocytes injected with rat brain mRNA.Nature310, 318–320. ArticlePubMedCAS Google Scholar
Mohler H. (1985) Molecular insights into GABA-receptor function.Neurosci, Abstr11, 946. Google Scholar
Kopito R. R. and Lodish H. F. (1985) Primary structure and transmembrane orientation of the chloride-bicarbonate exchange protein.Nature316, 234–238. ArticlePubMedCAS Google Scholar
Costa T., Russell L., Pert C., and Rodbard D. (1981) γ-Aminobutyric-acid-induced enhancement of diazepam receptors in rat of anion channels.Mol. Pharmacol.20, 470–476. PubMedCAS Google Scholar
Braestrup C. and Squires R. F. (1977) Specific benzodiazepine receptors in rat brain characterized by high affinity3H-diazepam binding.Proc. Natl. Acad. Sci. USA74, 3805–3809. ArticlePubMedCAS Google Scholar
Anholt R. R. H., DeSouza E. B., Oster-Granite M. L., and Snyder S. H. (1985) Peripheral-type benzodiazepine receptors: Autoradiographic localization in whole body sections of neonatal rats.J. Pharmacol. Exp. Ther.233, 517–526. PubMedCAS Google Scholar
Gallager D. W., Mallorga P., Oertel W., Henneberry R., and Tallman J. (1981) [3H]Diazepam binding in mammalian central nervous system: A pharmacological characterization.J. Neurosci.1, 218–225. PubMedCAS Google Scholar
Schoemaker H., Boles R. G., Horst W. D., and Yamamura H. I. (1983) Specific high-affinity binding sites for [3H] Ro5-4864 in rat brain and kidney.J. Pharmacol. Exp. Ther.225, 61–69. PubMedCAS Google Scholar
Marangos P. J., Patel J., Bouenger J. P., and Clark-Rosenberg R. (1982) Characterization of peripheral-type benzodiazepine binding sites in brain using [3H]-Ro5 4864.Mol. Pharmacol.22, 26–32. PubMedCAS Google Scholar
Wang J. K. T., Morgan J. I., and Spector S. (1984) Benzodiazepines that bind at peripheral sites inhibit cell proliferation.Proc. Natl. Acad. Sci. USA81, 753–756. ArticlePubMedCAS Google Scholar
Wang J. K. T., Morgan J. I., and Spector S. (1984) Differentiation of friend erythroleukemia cells induced by benzodiazepines.Proc. Natl. Acad. Sci. USA81, 3770–3772. ArticlePubMedCAS Google Scholar
LeFur G., Perrier M. L., Baucher N., Imbault F., Flamier A., Benavides J., Uzan A., Renault C., Dubroeucq M. C., and Gueremy C. (1983) Peripheral benzodiazepine binding sites: Effect of PK11195, 1-(2-chlorophenyl)-_N_-methyl-_N_-(1-methylpropy1)-3-isoquino linecarboxamide. I. In vitro studies.Life Sci.32, 1839–1997. ArticleCAS Google Scholar
LeFur G., Vaucher N., Perrier M. L., Flamier A., Benavides J., Renault C., Dubroeucq M. C., Guremy C., and Uzan (1983) Differentiation between two ligands for peripheral benzodiazepine binding sites, [H]Ro5-4864 and [3H]PK11195, by thermodynamic studies.Life Sci.33, 449–457. ArticleCAS Google Scholar
Burgevin M., Ferris O., Menager A., Doble A., Uzan A., and LeFur G. (1986) Purification of peripheral-type benzodiazepine binding sites from rat adrenal gland.Neurosci. Abst.12, 666. Google Scholar
Doble A., Benavides J., Ferris O., Bertrand P., Menager J., Vaucher N., Burgevin M. C., Uzan A., Guermy C., and LeFur G. (1985) Dihydropyridine and peripheral type benzodiazepine binding sites: Subcellular distribution and molecuar size determination.Eur. J. Pharmacol.119, 153–167. ArticlePubMedCAS Google Scholar
Lueddens H. W. M., Newman A. H., Rice K. C., and Skolnick P. (1986) AHN 086: An irreversible ligand of peripheral benzodiazepine receptors.Mol. Pharmacol.29, 540–545. PubMedCAS Google Scholar
Thomas J. W. and Tallman J. F. (1981) Solubilization of a non-neuronal benzodiazepine binding site.Neurosci. Abst,7, 321. Google Scholar
Gavish M. and Fanes F. (1985) Solubilization of peripheral-benzodiazepine-binding sites form rat kidney.J. Neurosci.5, 2889–2893. PubMedCAS Google Scholar
DeLorenzo R. J., Burdette S., and Holderness I. (1981) Benzodiazepine inhibition of calcium-calmodulin protein kinase system in brain membrane. Science213, 546–549. ArticlePubMedCAS Google Scholar
Mestre M., Carriot T., Belin C., Uzan A., Renault C., Dubroeucq M. C., Guermy C., Doble A., and LeFur G, (1984) Electyrophysiological and pharmacological evidence that peripheral type benzodiazepine receptors are coupled to calcium channels in the heart.Life Sci.36, 391–400. Article Google Scholar
Bisserbe J. C., Patel J., and Eskay R. L. (1986) Evidence that the peripheral-type benzodiazepine receptor ligand Ro5-4864 inhibits beta-endorphin release form AtT-20 cells by blockade of voltage-dependent calcium channels.J. Neurochem.47, 1419–1424. ArticlePubMedCAS Google Scholar
Cantor E. H., Kenessey A., Semenuk G., and Spector S. (1984) Interaction of calcium channel blockers with non-neuronal benzodiazepine binding sites.Proc. Natl. Acad. Sci. USA81, 1549–1552. ArticlePubMedCAS Google Scholar
Bolger G. T., Gengo P., Kloclowski R., Luchowski E., Siegel H., Janis R. A., Triggle A. M., and Triggle D. J. Characterization of binding of the Ca++ channel antagonist [3H]-nitrendipene, to guinea pig ileal smooth muscle.J. Pharmacol. Exp. Ther.225, 291–309.
Bolger G. T., Weissman B. A., Lucddens H., Basile A. S., Mantione C. R., Barrett J. E., Witkin J. M., Paul S. M., and Skolnick P. (1985) Late evolutionary appearance of peripheral-type binding sites for benzodiazepines.Brain Res.335, 366–370. Article Google Scholar
Bolger G. T., Weissman B. A., Luddens H., Barrett J. E., Witkin J., Paul S. M., and Skolnick D. (1986) Dihydropyridine calcium channel antagonist binding in non-mammalian vertebrates: Characterization and relationship to peripheral-type binding sites for benzodiazepines.Brain Res.368, 351–356. ArticlePubMedCAS Google Scholar
Abalis J. M., Eldefrawi M. E., and Eldefrawi A. T. (1985) Biochemical identification of putative GABA/benzodiazepine receptors in housefly thorax muscles.Pest. Biochem Phys.20, 34–48. Google Scholar
Robinson T., MacAllan D., Lunt G., and Battershy M. (1986) γ-aminobutyric acid receptor complex of insect CNS: Characterization of a benzodiazepine binding site.J. Neurochem.47, 1955–1962. ArticlePubMedCAS Google Scholar
Hebebrand J., Friedl W., Lentes K. U., and Propping P. (1986) Qualitative variation of photolabeled benzodiazepine receptors in different species.Neurochem. Int.8, 267–271. ArticleCAS Google Scholar
Hebebrand J., Friedl W., Unverzagt B., and Propping P. (1986) Benzodiazepine receptor subunits in avian brain.J. Neurochem.47, 790–793. PubMedCAS Google Scholar
Sigel E., Stephenson F. A., Mamalaki C., and Barnard E. A. (1983) γ-aminobutyric acid/benzodiazepine receptor complex of bovine cerebral cortex. Purification and partial characterization.J. Biol. Chem.258, 6965–6971. PubMedCAS Google Scholar
Aprison M. H. and Daly E. C. (1978) Biochemical aspects of transmission at inhibitory synapses: The role of glycine.Adv. Neuro Chem.3, 203–294. CAS Google Scholar
Werman R., Davidoff R. A., and Aprison M. H. (1967) Inhibition of motorneurons by iontophoresis of glycine.Nature214, 681–684. ArticlePubMedCAS Google Scholar
Graham L. T., Jr. Shank R. P., Weman R., and Aprison M. H. (1967) Distribution of some synaptic transmitter suspects in the cat spinal cord: Glutamic acid, aspartic acid, gamma-aminobutyric acid, glycine and glutamine.J. Neurochem.14, 1025–1031. ArticlePubMed Google Scholar
Bradford H. F. (1970) Metabolic response of synaptosomes to electrical stimulation: Release of amino acids.Brain Res.19, 239–247. ArticlePubMedCAS Google Scholar
Hopkin J. and Neal M. J. (1971) Effect of electrical and high potassium concentrations on the flux of [14C]-glycine from slice of spinal cord.Br. J. Pharmacol.42, 215–223. PubMedCAS Google Scholar
Curtis D. R., Hosli L. R., and Johnston G. A. R. (1986) A pharmacological study of the depression of spinal neurons by glycine and related amino acids.Exp. Brain Res.6, 1–18. Google Scholar
Krnjevic K. (1974) Chemical nature of synaptic transmission in vertebrates.Physiol. Rev.54, 418–540. CAS Google Scholar
Zarbin M. A., Wamsley J. K., and Kuhar M. J., (1981) Glycine receptors: Light microscopic autoradiographic localization with [3H]-strychnine.J. Neurosci.1, 532–547. PubMedCAS Google Scholar
Young A. B. and Snyder S. H. (1973) Strychnine binding associated with glycine receptors of the central nervous system.Proc. Natl. Acad. Sci. USA70, 2832–2836. ArticlePubMedCAS Google Scholar
Cunningham R. A. and Miller R. F. (1976) Taurine: Its selective action on neuronal pathways in the rabbit retina.Brain Res.117, 341–345. ArticlePubMedCAS Google Scholar
Young A. B. and Snyder S. H. (1974) The glycine synaptic receptor: Evidence that strychnine binding is associated with the ion conductance mechanism.Proc. Natl. Acad. Sci. USA71, 400–4005. Google Scholar
Barker J. L. and McBurney R. N. GABA and glycine may share the same conductance channel on cultured mammalian neurons. Nature277, 234–236.
Pfeiffer F. and Betz H. (1981) Solubilization of the glycine receptor from rat spinal cord.Brain Res.226, 273–279. ArticlePubMedCAS Google Scholar
Pfeiffer F., Graham D., and Betz H. (1982) Purification by affinity chromatography of the glycine receptor of rat spinal cord.J. Biol. Chem.257, 9389–9393. PubMedCAS Google Scholar
Schmitt B., Knaus P., Becker G. M., and Betz H. (1986) The_M_, 93000 polypeptide of the postsynaptic glycine receptor complex is a cytoplasmically localized peripheral membrane protein.Neurosci. Abst.12, 659. Google Scholar
Graham D., Pfeiffer P., Simler R., and Betz H. (1985) Purification and characterization of the glycine receptor of pig spinal cord.Biochemistry24, 990–994. ArticlePubMedCAS Google Scholar
Graham D., Pfeiffer F., and Betz H. (1983) Photoaffinity-labelling of the glycine receptor of the rat spinal cord.Eur. J. Biochem.131, 519–525. ArticlePubMedCAS Google Scholar
Pfeiffer F., Simler R., Grenningloh G., and Betz H. (1984) Monoclonal antibodies and peptide mapping reveal structural similarities between the subunits of the glycine receptors of the rat spinal cord.Proc. Natl. Acad. Sci. USA81, 7224–7227. ArticlePubMedCAS Google Scholar
St. John P. A., Owen D. G., Barker J. L., Pfeiffer F., and Betz H. (1984) Monoclonal antibodies to purified glycine receptor alter binding to glycine receptors on mouse spinal cord neurons in culture.Neurosci. Abst.10, 7. Google Scholar
Graham D., Pfeiffer F., and Betz H. (1982) Avermectin B1a inhibits the binding of strychnine to the glycine receptor of the rat spinal cord.Neurosci. Lett.29 173–176. ArticlePubMedCAS Google Scholar