Dopamine induces supernumerary centrosomes and subsequent cell death through Cdk2 up-regulation in dopaminergic neuronal cells (original) (raw)

References

• Alvira D, M Tajes, E Verdaguer, SG de Arriba, C Allgaier, C Matute, R Trullas, A Jimenez, M Pallas and A Camins (2007) Inhibition of cyclin-dependent kinases is neuroprotective in 1-methyl-4-phenylpyridinium-induced apoptosis in neurons.Neuroscience 146, 350–365.
  Article CAS PubMed Google Scholar
• Andorfer C, CM Acker, Y Kress, PR Hof, K Duff and P Davies (2005) Cell-cycle reentry and cell death in transgenic mice expressing nonmutant human tau isoforms.J. Neurosci. 25, 5446–5454.
  Article CAS PubMed Google Scholar
• Asanuma M, I Miyazaki and N Ogawa (2003) Dopamine- or L-DOPA-induced neurotoxicity: the role of dopamine qui-none formation and tyrosinase in a model of Parkinson’s disease.Neurotox. Res. 5, 165–176.
  Article Google Scholar
• Berman SB and TG Hastings (1999) Dopamine oxidation alters mitochondrial respiration and induces permeability transition in brain mitochondria: implications for Parkinson’s disease.J. Neurochem. 73, 1127–1137.
  Article CAS PubMed Google Scholar
• Braak H, E Braak, D Yilmazer, C Schultz, RA de Vos and EN Jansen (1995) Nigral and extranigral pathology in Parkinson’s disease.J. Neural Transm. Suppl. 46, 15–31.
  CAS PubMed Google Scholar
• Ciciarello M, R Mangiacasale, M Casenghi, M Zaira Limongi, M D’Angelo, S Soddu, P Lavia and E Cundari (2001) p53 displacement from centrosomes and p53-mediated G1 arrest following transient inhibition of the mitotic spindle.J. Biol. Chem. 276, 19205–19213. Epub 12001 Feb 19228.
  Article CAS PubMed Google Scholar
• Conway KA, JC Rochet, RM Bieganski and PT Lansbury Jr (2001) Kinetic stabilization of the a-synuclein protofibril by a dopamine-α-synuclein adduct.Science 294, 1346–1349.
  Article CAS PubMed Google Scholar
• Cyr M, JM Beaulieu, A Laakso, TD Sotnikova, WD Yao, LM Bohn, RR Gainetdinov and MG Caron (2003) Sustained elevation of extracellular dopamine causes motor dysfunction and selective degeneration of striatal GABAergic neurons.Proc. Natl. Acad. Sci. USA 100, 11035–11040.
  Article CAS PubMed Google Scholar
• Delattre M and P Gonczy (2004) The arithmetic of centrosome biogenesis.J. Cell. Sci. 117, 1619–1630.
  Article CAS PubMed Google Scholar
• Diaz-Corrales FJ, M Asanuma, I Miyazaki, K Miyoshi and N Ogawa (2005) Rotenone induces aggregation of γ-tubulin protein and subsequent disorganization of the centrosome: relevance to formation of inclusion bodies and neurodegen-eration.Neuroscience 133, 117–135.
  Article CAS PubMed Google Scholar
• El-Khodor BF, TF Oo, N Kholodilov and RE Burke (2003) Ectopic expression of cell cycle markers in models of induced programmed cell death in dopamine neurons of the rat substantia nigra pars compacta.Exp. Neurol. 179, 17–27.
  Article CAS PubMed Google Scholar
• Emdadul Haque M, M Asanuma, Y Higashi, I Miyazaki, K Tanaka and N Ogawa (2003) Apoptosis-inducing neurotoxicity of dopamine and its metabolites via reactive quinone generation in neuroblastoma cells.Biochim. Biophys. Acta 1619, 39–52.
  Google Scholar
• Fahn S, D Oakes, I Shoulson, K Kieburtz, A Rudolph, A Lang, CW Olanow, C Tanner and K Marek (2004) Levodopa and the progression of Parkinson’s disease.N. Engl. J. Med. 351, 2498–2508.
  Article CAS PubMed Google Scholar
• Forno LS (1996) Neuropathology of Parkinson’s disease.J. Neuropathol. Exp. Neurol. 55, 259–272.
  Article CAS PubMed Google Scholar
• Honda R, ED Lowe, E Dubinina, V Skamnaki, A Cook, NR Brown and LN Johnson (2005) The structure of cyclin E1/ CDK2: implications for CDK2 activation and CDK2-independent roles.EMBO J. 24, 452–463.
  Article CAS PubMed Google Scholar
• Hoozemans JJ, MK Bruckner, AJ Rozemuller, R Veerhuis, P Eikelenboom and T Arendt (2002) Cyclin D1 and cyclin E are co-localized with cyclo-oxygenase 2 (COX-2) in pyramidal neurons in Alzheimer disease temporal cortex.J. Neuropathol. Exp. Neurol. 61, 678–688.
  CAS PubMed Google Scholar
• Husseman JW, D Nochlin and I Vincent (2000) Mitotic activation: a convergent mechanism for a cohort of neurodegen-erative diseases.Neurobiol. Aging 21, 815–828.
  Article CAS PubMed Google Scholar
• Jellinger KA (2003) General aspects of neurodegeneration.J. Neural Transm. Suppl. 65, 101–144.
  PubMed Google Scholar
• Johnson K, L Liu, N Majdzadeh, C Chavez, PC Chin, B Morrison, L Wang, J Park, P Chugh, HM Chen and SR D’Mello (2005) Inhibition of neuronal apoptosis by the cyclin-dependent kinase inhibitor GW8510: identification of 3’substituted indolones as a scaffold for the development of neuroprotective drugs.J. Neurochem. 93, 538–548.
  Article CAS PubMed Google Scholar
• Johnston JA, CL Ward and RR Kopito (1998) Aggresomes: a cellular response to misfolded proteins.J. Cell. Biol. 143, 1883–1898.
  Article CAS PubMed Google Scholar
• Kawamura K, H Izumi, Z Ma, R Ikeda, M Moriyama, T Tanaka, T Nojima, LS Levin, K Fujikawa-Yamamoto, K Suzuki and K Fukasawa (2004) Induction of centrosome amplification and chromosome instability in human bladder cancer cells by p53 mutation and cyclin E overexpression.Cancer Res. 64, 4800–4809.
  Article CAS PubMed Google Scholar
• Klein JA and SL Ackerman (2003) Oxidative stress, cell cycle, and neurodegeneration.J. Clin. Invest. 111, 785–793.
  CAS PubMed Google Scholar
• Kopito RR (2000) Aggresomes, inclusion bodies and protein aggregation.Trends Cell. Biol. 10, 524–530.
  Article CAS PubMed Google Scholar
• Lacey KR, PK Jackson and T Stearns (1999) Cyclin-dependent kinase control of centrosome duplication.Proc. Natl. Acad. Sci. USA 96, 2817–2822.
  Article CAS PubMed Google Scholar
• LaVoie MJ, BL Ostaszewski, A Weihofen, MG Schlossmacher and DJ Selkoe (2005) Dopamine covalently modifies and functionally inactivates parkin.Nat. Med. 11, 1214–1221. Epub 2005 Oct 1216.
  Article CAS PubMed Google Scholar
• Lee SS, YM Kim, E Junn, G Lee, KH Park, M Tanaka, RD Ronchetti, MM Quezado and MM Mouradian (2003) Cell cycle aberrations by α-synuclein over-expression and cyclin B immunoreactivity in Lewy bodies.Neurobiol. Aging 24, 687–696.
  Article CAS PubMed Google Scholar
• Lingle WL, SL Barrett, VC Negron, AB D’Assoro, K Boeneman, W Liu, CM Whitehead, C Reynolds and JL Salisbury (2002) Centrosome amplification drives chromosomal instability in breast tumor development.Proc. Natl. Acad. Sci. USA 99, 1978–1983.
  Article CAS PubMed Google Scholar
• Marx FP, AS Soehn, D Berg, C Melle, C Schiesling, M Lang, S Kautzmann, KM Strauss, T Franck, S Engelender, J Pahnke, S Dawson, F von Eggeling, JB Schulz, O Riess and R Kruger (2007) The proteasomal subunit S6 ATPase is a novel synphilin-1 interacting protein - implications for Parkinson’s disease.FASEB J. 21, 1759–1767.
  Article CAS PubMed Google Scholar
• McNaught KS, P Shashidharan, DP Perl, P Jenner and CW Olanow (2002) Aggresome-related biogenesis of Lewy bodies.Eur. J. Neurosci. 16, 2136–2148.
  Article PubMed Google Scholar
• Moroy T and C Geisen (2004) Cyclin E.Int. J. Biochem. Cell Biol. 36, 1424–1439.
  Article CAS PubMed Google Scholar
• Murray AW (2004) Recycling the cell cycle: cyclins revisited.Cell 116, 221–234.
  Article CAS PubMed Google Scholar
• Nguyen MD, WE Mushynski and JP Julien (2002) Cycling at the interface between neurodevelopment and neurodegener-ation.Cell Death Differ. 9, 1294–1306.
  Article CAS PubMed Google Scholar
• Oakley CE and BR Oakley (1989) Identification of γ-tubulin, a new member of the tubulin superfamily encoded by mipA gene of Aspergillus nidulans.Nature 338, 662–664.
  Article CAS PubMed Google Scholar
• Ogawa N, M Asanuma, I Miyazaki, FJ Diaz-Corrales and K Miyoshi (2005) L-DOPA treatment from the viewpoint of neuroprotection. Possible mechanism of specific and progressive dopaminergic neuronal death in Parkinson’s disease.J. Neurol. 252, IV23-IV31.
  Article PubMed Google Scholar
• Olanow CW, DP Perl, GN DeMartino and KS McNaught (2004) Lewy-body formation is an aggresome-related process: a hypothesis.Lancet Neurol. 3, 496–503.
  Article PubMed Google Scholar
• Petrozzi L, C Lucetti, R Scarpato, G Gambaccini, F Trippi, S Bernardini, P Del Dotto, L Migliore and U Bonuccelli (2002) Cytogenetic alterations in lymphocytes of Alzheimer’s disease and Parkinson’s disease patients.Neurol. Sci. 23 Suppl 2, S97-S98.
  Article PubMed Google Scholar
• Sathasivam K, B Woodman, A Mahal, F Bertaux, EE Wanker, DT Shima and GP Bates (2001) Centrosome disorganization in fibroblast cultures derived from R6/2 Huntington’s disease (HD) transgenic mice and HD patients.Hum. Mol. Genet. 10, 2425–2435.
  Article CAS PubMed Google Scholar
• Smith MZ, Z Nagy and MM Esiri (1999) Cell cycle-related protein expression in vascular dementia and Alzheimer’s disease.Neurosci. Lett. 271, 45–48.
  Article CAS PubMed Google Scholar
• Smith PD, SJ Crocker, V Jackson-Lewis, KL Jordan-Sciutto, S Hayley, MP Mount, MJ O’Hare, S Callaghan, RS Slack, S Przedborski, H Anisman and DS Park (2003) Cyclin- dependent kinase 5 is a mediator of dopaminergic neuron loss in a mouse model of Parkinson’s disease.Proc. Natl. Acad. Sci. USA 100, 13650–13655.
  Article CAS PubMed Google Scholar
• Stearns T, L Evans and M Kirschner (1991) γ-Tubulin is a highly conserved component of the centrosome.Cell 65, 825–836.
  Article CAS PubMed Google Scholar
• Sunkel CE, R Gomes, P Sampaio, J Perdigao and C Gonzalez (1995) γ-Tubulin is required for the structure and function of the microtubule organizing centre in Drosophila neuroblasts.EMBO J. 14, 28–36.
  Google Scholar
• van Muiswinkel FL, RA de Vos, JG Bol, G Andringa, EN Jansen Steur, D Ross, D Siegel and B Drukarch (2004) Expression of NAD(P)H:quinone oxidoreductase in the normal and Parkinsonian substantia nigra.Neurobiol. Aging 25, 1253–1262.
  Article PubMed Google Scholar
• Whitehead RE, JV Ferrer, JA Javitch and JB Justice (2001) Reaction of oxidized dopamine with endogenous cysteine residues in the human dopamine transporter.J. Neurochem. 76, 1242–1251.
  Article CAS PubMed Google Scholar
• Wigley WC, RP Fabunmi, MG Lee, CR Marino, S Muallem, GN DeMartino and PJ Thomas (1999) Dynamic association of proteasomal machinery with the centrosome.J. Cell. Biol. 145, 481–490.
  Article Google Scholar
• Xu J, SY Kao, FJ Lee, W Song, LW Jin and BA Yankner (2002) Dopamine-dependent neurotoxicity of a-synuclein: a mechanism for selective neurodegeneration in Parkinson disease.Nat. Med. 8, 600–606.
  Article CAS PubMed Google Scholar
• Xu Y, AH Stokes, RJ Roskoski and KE Vrana (1998) Dopamine, in the presence of tyrosinase, covalently modifies and inactivates tyrosine hydroxylase.J. Neurosci. Res. 54, 691–697.
  Article CAS PubMed Google Scholar
• Yoshimoto Y, K Nakaso and K Nakashima (2005) L-dopa and dopamine enhance the formation of aggregates under protea- some inhibition in PC12 cells.FEBS Lett. 579, 1197–1202.
  Article CAS PubMed Google Scholar

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