The role of D1 dopamine receptors and phospho-ERK in mediating cytotoxicity. Commentary (original) (raw)

• Andringa G, JC Stoof and AR Cools (1999) Sub-chronic administration of the dopamine D(1) antagonist SKF 83959 in bilaterally MPTP-treated rhesus monkeys, stable therapeutic effects and wearing-off dyskinesia.Psychopharmacology (Berl.) 146, 328–334.
  Article CAS Google Scholar
• Atkins CM, JC Selcher, JJ Petraitis, JM Trzaskos and JD Sweatt (1998) The MAPK cascade is required for mammalian associative learning.Nat. Neurosci. 1, 602–609.
  Article PubMed CAS Google Scholar
• Bronstein DM and JS Hong (1995) Effects of sulpiride and SCH 23390 on methamphetamine-induced changes in body temperature and lethality.J. Pharmacol. Exp. Ther. 274, 943–950.
  PubMed CAS Google Scholar
• Brunet A, D Roux, P Lenormand, S Dowd, S Keyse and J Pouyssegur (1999) Nuclear translocation of p42/p44 mitogen-activated protein kinase is required for growth factor-induced gene expression and cell cycle entry.EMBO J. 18, 664–674.
  Article PubMed CAS Google Scholar
• Camps M, A Nichols, C Gillieron, B Antonsson, M Muda, C Chabert, U Boschert and S Arkinstall (1998) Catalytic activation of the phosphatase MKP-3 by ERK2 mitogen-activated protein kinase.Science 280, 1262–1265.
  Article PubMed CAS Google Scholar
• Chang L and M Karin (2001) Mammalian MAP kinase signalling cascades.Nature 410, 37–40.
  Article PubMed CAS Google Scholar
• Chen J, C Wersinger and A Sidhu (2003) Chronic stimulation of D1 dopamine receptors in human SK-N-MC neuroblastoma cells induces nitric-oxide synthase activation and cytotoxicity.J. Biol. Chem. 278, 28089–28100.
  Article PubMed CAS Google Scholar
• Chen RH, C Sarnecki and J Blenis (1992) Nuclear localization and regulation of erk- and rsk-encoded protein kinases.Mol. Cell. Biol. 12, 915–927.
  PubMed CAS Google Scholar
• Chu CT, DJ Levinthal, SM Kulich, EM Chalovich and DB DeFranco (2004) Oxidative neuronal injury. The dark side of ERK1/2.Eur. J. Biochem. 271, 2060–2066.
  Article PubMed CAS Google Scholar
• Colucci-D’Amato L, C Perrone-Capano and U di Porzio (2003) Chronic activation of ERK and neurodegenerative diseases.Bioessays 25, 1085–1095.
  Article PubMed CAS Google Scholar
• Cools AR, L Lubbers, RV van Oosten and G Andringa (2002) SKF 83959 is an antagonist of dopamine D1-like receptors in the pre-frontal cortex and nucleus accumbens, a key to its antiparkin-sonian effect in animals?Neuropharmacology 42, 237–245.
  Article PubMed CAS Google Scholar
• Davis RJ (2000) The mitogen-activated protein kinase signal trans-duction pathway.J. Biol. Chem. 268, 14553–14556.
  Google Scholar
• English JD and JD Sweatt (1996) Activation of p42 mitogen-acti-vated protein kinase in hippocampal long term potentiation.J. Biol. Chem. 271, 24329–24332.
  Article PubMed CAS Google Scholar
• Ferrer I, R Blanco, M Carmona, B Puig, M Barrachina, C Gomez and S Ambrosio (2001a) Active, phosphorylation-dependent mitogen-activated protein kinase (MAPK/ERK), stress-activated protein kinase/c-Jun N-terminal kinase (SAPK/JNK), and p38 kinase expression in Parkinson’s disease and Dementia with Lewy bodies.J. Neural Transm. 108, 1383–1396.
  Article PubMed CAS Google Scholar
• Ferrer I, R Blanco, M Carmona, R Ribera, E Goutan, B Puig, MJ Rey, A Cardozo, F Vinals and T Ribalta (2001b) Phosphorylated map kinase (ERK1, ERK2) expression is associated with early tau deposition in neurones and glial cells, but not with increased nuclear DNA vulnerability and cell death, in Alzheimer disease, Pick’s disease, progressive supranuclear palsy and corticobasal degeneration.Brain Pathol. 11, 144–158.
  PubMed CAS Google Scholar
• Fukuda M, Y Gotoh and E Nishida (1997) Interaction of MAP kinase with MAP kinase kinase, its possible role in the control of nucleo-cytoplasmic transport of MAP kinase.EMBO J. 16, 1901–1908.
  Article PubMed CAS Google Scholar
• Gille H, M Kortenjann, O Thomae, C Moomaw, C Slaughter, MH Cobb and PE Shaw (1995) ERK phosphorylation potentiates Elk-1-mediated ternary complex formation and transactivation.EMBO J. 14, 951–962.
  PubMed CAS Google Scholar
• Grewal SS, RD York, PJ Stork (1999) Extracellular-signal-regulated kinase signalling in neurons.Curr. Opin. Neurobiol. 9, 544–553.
  Article PubMed CAS Google Scholar
• Hall RA and RJ Lefkowitz (2002) Regulation of G protein-coupled receptor signaling by scaffold proteins.Circ. Res. 91, 672–680.
  Article PubMed CAS Google Scholar
• Khokhlatchev AV, B Canagarajah, J Wilsbacher, M Robinson, M Atkinson, E Goldsmith and MH Cobb (1998) Phosphorylation of the MAP kinase ERK2 promotes its homodimerization and nuclear translocation.Cell 93, 605–615.
  Article PubMed CAS Google Scholar
• Kim OJ, BR Gardner, DB Williams, PS Marinec, DM Cabrera, JD Peters, CC Mak, KM Kim and DR Sibley (2004) The role of phosphorylation in D1 dopamine receptor desensitization, evidence for a novel mechanism of arrestin association.J. Biol. Chem. 279, 7999–8010.
  Article PubMed CAS Google Scholar
• Pearson G, F Robinson, T Beers Gibson, BE Xu, M Karandikar, K Berman and MH Cobb (2001) Mitogen-activated protein (MAP) kinase pathways, regulation and physiological functions.Endocr. Rev. 22, 153–183.
  Article PubMed CAS Google Scholar
• Pouyssegur J, V Volmat and P Lenormand (2003) Fidelity and spatio-temporal control in MAP kinase (ERKs) signalling.Biochem. Pharmacol. 64, 755–763.
  Article Google Scholar
• Reszka AA, R Seger, CD Diltz, EG Krebs and EH Fischer (1995) Association of mitogen-activated protein kinase with the micro-tubule cytoskeleton.Proc. Natl. Acad. Sci. USA 92, 8881–8885.
  Article PubMed CAS Google Scholar
• Rubinfeld H, T Hanoch and R Seger (1999) Identification of a cyto-plasmic-retention sequence in ERK2.J. Biol. Chem. 274, 30349–30352.
  Article PubMed CAS Google Scholar
• Segal RA and ME Greenberg (1996) Intracellular signaling pathways activated by neurotrophic factors.Annu. Rev. Neurosci. 19, 463–489.
  PubMed CAS Google Scholar
• Sidhu A and PH Fishman (1990) Identification and characterization of functional D1 dopamine receptors in a human neuroblastoma cell line.Biochem. Biophys. Res. Commun. 166, 574–579.
  Article PubMed CAS Google Scholar
• Sweatt JD (2001) The neuronal MAP kinase cascade, a biochemical signal integration system subserving synaptic plasticity and memory.J. Neurochem. 76, 1–10.
  Article PubMed CAS Google Scholar
• Takaki M, H Ujike, M Kodama, Y Takehisa, K Nakata and S Kuroda (2001) Two kinds of mitogen-activated protein kinase phosphatases, MKP-1 and MKP-3, are differentially activated by acute and chronic methamphetamine treatment in the rat brain.J. Neurochem. 79, 679–688.
  Article PubMed CAS Google Scholar
• Wersinger C, J Chen and A Sidhu (2004) Bimodal induction of dopamine-mediated striatal neurotoxicity is mediated through both activition of D1 dopamine receptors and autoxidation.Mol. Cell. Neurosci. 25, 124–137.
  Article PubMed CAS Google Scholar
• Xia Z, M Dickens, J Raingeaud, RJ Davis and ME Greenberg (1995) Opposing effects of ERK and JNK-p38 MAP kinases on apoptosis.Science 270, 1326–1331.
  Article PubMed CAS Google Scholar
• Zhu JH, SM Kulich, TD Oury and CT Chu (2002) Cytoplasmic aggregates of phosphorylated extracellular signal-regulated protein kinases in Lewy body diseases.Am. J. Pathol. 161, 2087–2098.
  PubMed CAS Google Scholar