The Role of a Single Formin Isoform in the Limb and Renal Phenotypes of Limb Deformity (original) (raw)

• Lyon MF, Searle AG. (1989) Genetic Variants and Strains of the Laboratory Mouse, 2nd ed. Oxford University Press, Oxford.
  Google Scholar
• Jones KL. (1988) Smith’s Recognizable Patterns of Human Malformation. W.B. Saunders, Philadelphia.
  Google Scholar
• Cupp MB. (1960) Mouse News Letter 22:50.
  Google Scholar
• Cupp MB. (1962) Mouse News Letter 26:51.
  Google Scholar
• Green MC. (1962) Mouse News Letter 26:34.
  Google Scholar
• Kleinebrecht J. (1974) Mouse News Letter 51: 19.
  Google Scholar
• Woychik RP, Stewart TA, Davis LG, D’Eustachio P, Leder P. (1985) An inherited limb deformity created by insertional mutagenesis in a transgenic mouse. Nature 318: 36–40.
  Article CAS PubMed Google Scholar
• Messing A, Behringer RR, Slapeak JR, Lemke G, Palmiter RD, Brinster RL. (1990) Insertional mutagenesis at the ld locus (again!) in a line of transgenic mice. Mouse Genome 87:107.
  PubMed PubMed Central CAS Google Scholar
• Woychik RP, Generoso WM, Russell LB, Cain KT, Cacheiro NL, Bultman SJ, Selby PB, Dickinson ME, Hogan BL, Rutledge JC. (1990) Molecular and genetic characterization of a radiation-induced structural rearrangement in mouse chromosome 2 causing mutations at the limb deformity and agouti loci. Proc. Natl. Acad. Sci. U.S.A. 87:2588–2592.
  Article CAS PubMed PubMed Central Google Scholar
• Maas R, Elfering S, Glaser T, Jepeal L. (1994) Deficient outgrowth of the ureteric bud underlies the renal agenesis phenotype in mice manifesting the limb deformity (ld) mutation. Dev. Dyn. 199:214–228.
  Article CAS PubMed Google Scholar
• Jackson-Grusby L, Kuo A, Leder P. (1992) A variant limb deformity transcript expressed in the embryonic mouse limb defines a novel formin. Genes Dev. 6:29–37.
  Article CAS PubMed Google Scholar
• Wang CC, Chan DC, Leder P (1997) The mouse formin (Fmn) gene: genomic structure, novel exons, and genetic mapping. Genomics 39:303–311.
  Article CAS PubMed Google Scholar
• Chan DC, Wynshaw-Boris A, Leder P. (1995) Formin isoforms are differentially expressed in the mouse embryo and are required for normal expression of fgf-4 and shh in the limb bud. Development 121:1351–1362.
  Google Scholar
• Trumpp A, Blundell PA, de la Pompa J, Zeller R. (1992) The chicken limb deformity gene encodes nuclear proteins expressed in specific cell types during morphogenesis. Genes Dev. 6: 14–28.
  Article CAS PubMed Google Scholar
• Tybulewicz VL, Crawford CE, Jackson PK, Bronson RT, Mulligan RC. (1991) Neonatal lethality and lymphopenia in mice with a homozygous disruption of the c-abl protooncogene. Cell 65:1153–1163.
  Article CAS PubMed Google Scholar
• Li E, Bestor TH, Jaenisch R. (1992) Targeted mutation of the DNA methyltransferase gene results in embryonic lethality. Cell 69: 915–926.
  Article CAS PubMed Google Scholar
• Deng C-X, Wynshaw-Boris A, Shen MM, Daugherty C, Ornitz D, Leder P. (1994) Murine FGFR-1 is required for early postimplantation growth and axial organization. Genes Dev. 8:3045–3057.
  Article CAS PubMed Google Scholar
• McLeod MJ. (1980) Differential staining of cartilage and bone in whole mouse fetuses by alcian blue and alizarin red S. Teratology 22: 299–301.
  Article CAS PubMed Google Scholar
• Kleinebrecht J, Selow J, Winkler W. (1982) The mouse mutant limb-deformity (ld). Anat. Am. 152:313–324.
  CAS Google Scholar
• Vogt TF, Jackson-Grusby L, Wynshaw-Boris AJ, Chan DC, Leder P. (1992) The same genomic region is disrupted in two transgene-induced limb deformity alleles. Mamm. Genome 3:431–437.
  Article CAS PubMed Google Scholar
• Wilkinson DG. (1992) Whole mount in situ hybridization of vertebrate embryos. In: Wilkinson DG (ed). In Situ Hybridization: A Practical Approach. IRL Press, Oxford, pp. 75–83.
  Google Scholar
• Rosen B, Beddington RSP. (1993) Whole-mount in situ hybridization in the mouse embryo: Gene expression in three dimensions. Trends Genet. 9:162–167.
  Article CAS PubMed Google Scholar
• Harlow E, Lane D. (1988) Antibodies: A Laboratory Manual. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, New York.
  Google Scholar
• Woychik RP, Maas RL, Zeller R, Vogt TF, Leder P. (1990) ‘Formins’: Proteins deduced from the alternative transcripts of the limb deformity gene. Nature 346:850–853.
  Article CAS PubMed Google Scholar
• Vogt TF, Jackson-Grusby L, Rush J, Leder P. (1993) Formins: phosphoprotein isoforms encoded by the mouse limb deformity locus. Proc. Natl. Acad. Sci. U.S.A. 90:5554–5558.
  Article CAS PubMed PubMed Central Google Scholar
• Zeller R, Jackson-Grusby L, Leder P. (1989) The limb deformity gene is required for apical ectodermal ridge differentiation and anteroposterior limb pattern formation. Genes Dev. 3:1481–1492.
  Article CAS PubMed Google Scholar
• Tabin C. (1995) The initiation of the limb bud: Growth factors, Hox genes, and retinoids. Cell 80:671–674.
  Article CAS PubMed Google Scholar
• Riddle RD, Johnson RL, Laufer E, Tabin C. (1993) Sonic hedgehog mediates the polarizing activity of the ZPA. Cell 75:1401–1416.
  Article CAS PubMed Google Scholar
• Johnson RL, Riddle RD, Laufer E, Tabin C. (1994) Sonic hedgehog: A key mediator of anterior-posterior patterning of the limb and dorso-ventral patterning of axial embryonic structures. Biochem. Soc. Trans. 22:569–574.
  Article CAS PubMed Google Scholar
• Niswander L, Martin GR. (1993) Mixed signals from the AER: FGF-4 and Bmp-2 have opposite effects on limb growth. Prog. Clin. Biol. Res. 383B:625–633.
  PubMed CAS Google Scholar
• Niswander L, Tickle C, Vogel A, Booth I, Martin GR. (1993) FGF-4 replaces the apical ectodermal ridge and directs outgrowth and patterning of the limb. Cell 75:579–587.
  Article CAS PubMed Google Scholar
• Niswander L, Martin GR. (1993) FGF-4 and BMP-2 have opposite effects on limb growth. Nature 361:68–71.
  Article CAS PubMed Google Scholar
• Niswander L, Tickle C, Vogel A, Martin G. (1994) Function of FGF-4 in limb development. Mol. Reprod. Dev. 39:83–88; discussion 88–89.
  Article CAS PubMed Google Scholar
• Niswander L, Jeffrey S, Martin GR, Tickle C. (1994) A positive feedback loop coordinates growth and patterning in the vertebrate limb. Nature 371:609–612.
  Article CAS PubMed Google Scholar
• Parr BA, McMahon AP. (1995) Dorsalizing signal Wnt-7a required for normal polarity of D-V and A-P axes of mouse limb. Nature 374:350–353.
  Article CAS PubMed Google Scholar
• Kuhlman J, Niswander L. (1997) Limb deformity proteins: Role in mesodermal induction of the apical ectodermal ridge. Development 124:133–139.
  PubMed CAS Google Scholar
• Kreidberg JA, Sariola H, Loring JM, Maeda M, Pelletier J, Housman D, Jaenisch R. (1993) WT-1 is required for early kidney development. Cell 74:679–691.
  Article CAS PubMed Google Scholar
• Schuchardt A, D’Agati V, Larsson-Blomberg L, Costantini F, Pachnis V. (1994) Defects in the kidney and enteric nervous system of mice lacking the tyrosine kinase receptor Ret. Nature 367:380–383.
  Article CAS PubMed Google Scholar
• Sanchez MP, Silos-Santiago I, Frisen J, He B, Lira SA, Barbacid MA. (1996) Renal agenesis and the absence of enteric neurons in mice lacking GDNF. Nature 382:70–73.
  Article CAS PubMed Google Scholar
• Pichel JG, Shen L, Sheng HZ, Granholm A-C, Drago J, Grinberg A, Lee EJ, Huang SP, Saarma M, Hoffer BJ, Sariola H, Westphal H. (1996) Defects in enteric innervation and kidney development in mice lacking GDNF. Nature 382:73–76.
  Article CAS PubMed Google Scholar
• Moore MW, Klein RD, Farinas I, Sauer H, Armanini M, Phillips H, Reichardt LF, Ryan AM, Carver-Moore K, Rosenthal A. (1996) Renal and neuronal abnormalities in mice lacking GDNF. Nature 382:76–79.
  Article CAS PubMed Google Scholar
• Stark K, Vainio S, Vassileva G, McMahon A. (1994) Epithelial transformation of metanephric mesenchyme in the developing kidney regulated by Wnt-4. Nature 372:679–683.
  Article CAS PubMed Google Scholar
• Torres M, Gomez-Pardo E, Dressler GR, Gruss P. (1995) Pax-2 controls multiple steps of urogenital development. Development 121: 4057–4065.
  PubMed CAS Google Scholar
• Pelletier J, Schalling M, Buckler AJ, Rogers A, Haber DA, Housman D. (1991) Expression of the Wilm’s tumor gene WT-1 in the murine urogenital system. Genes Dev. 5:1345–1356.
  Article CAS PubMed Google Scholar
• Armstrong JF, Pritchard-Jones K, Bickmore WA, Hastie ND, Bard JBL. (1992) The expression of the Wilm’s tumor gene, WT-1, in the developing mammalian embryo. Mech. Dev. 40:85–97.
  Article Google Scholar
• Pachnis V, Mankoo BS, Costantini F. (1993) Expression of the c-ret proto-oncogene during mouse embryogenesis. Development 119: 1005–1017.
  PubMed CAS Google Scholar
• Roodhooft AM, Birnholz JC, Holmes LB. (1984) Familial nature of congenital absence and severe dysgenesis of both kidneys. New Engl. J. Med. 310:1341–1345.
  Article CAS PubMed Google Scholar
• Bankier A, deCampo M, Newell R, Rogers JG, Danks DM. (1985) A pedigree study of perinatally lethal renal disease. J. Med. Genet. 22:104–111.
  Article CAS PubMed PubMed Central Google Scholar
• Battin J, Lacombe D, Leng J-J. (1993) Familial occurrence of hereditary renal adysplasia with Mullerian anomalies. Clin. Genet. 43: 23–24.
  Article CAS PubMed Google Scholar