Requirements for Allergen-Induced Airway Hyperreactivity in T and B Cell-Deficient Mice (original) (raw)
Walker C, Virchow J-C Jr, Bruijnzeel PLB, Blaser K. (1991) T cell subsets and their soluble products regulate eosinophilia in allergic and nonallergic asthma. J. Immunol.146: 1829–1835. PubMedCAS Google Scholar
Robinson DS, Hamid Q, Ying S, et al. (1992) Predominant Th2-like bronchoalveolar T-lymphocyte population in atopic asthma. N. Engl. J. Med.326: 298–304. ArticleCASPubMed Google Scholar
Leung DYM, Martin RJ, Szefler SJ, et al. (1995) Dysregulation of interleukin 4, interleukin 5, and interferon γ gene expression in steroid-resistant asthma. J. Exp. Med.181: 33–40. ArticleCASPubMed Google Scholar
Wallaert BP, Desreumaux MC, Copin I, et al. (1995) Immunoreactivity for interleukin 3 and 5 and granulocyte/macrophage colony-stimulating factor of intestinal mucosa in bronchial asthma. J. Exp. Med.182: 1897–1904. ArticleCASPubMed Google Scholar
Robinson DS, Tsicopoulos A, Meng Q, Durham S, Kay AB, Hamid Q. (1996) Increased interleukin-10 messenger RNA expression in atopic allergy and asthma. Am. J. Respir. Cell Mol. Biol.14: 113–117. ArticleCASPubMed Google Scholar
Goldstein RA, Paul WE, Metcalfe DD, Busse WW, Reece ER. (1994) Asthma. Ann. Intern. Med.121: 698–708. ArticleCASPubMed Google Scholar
Corry DB, Folkesson HG, Warnock ML, Erle DJ, Matthay MA, Wiener-Kronish JP, Locksley RM. (1996) Interleukin 4, but not interleukin 5 or eosinophils, is required in a murine model of acute airway hyperreactivity. J. Exp. Med.183: 109–117. ArticleCASPubMed Google Scholar
Gavett SH, Chen X, Finkelman F, Wills-Karp M. (1994) Depletion of murine CD4+ T lymphocytes prevents antigen-induced airway hyperreactivity and pulmonary eosinophilia. Am. J. Respir. Cell Mol. Biol10: 587–593. ArticleCASPubMed Google Scholar
Garlisi CG, Falcone A, Kung TT, et al. (1995) T cells are necessary for Th2 cytokine production and eosinophil accumulation in airways of antigen-challenged allergic mice. Clin. Immunol. Immu-nopathol.75: 75–83. ArticleCAS Google Scholar
Gonzalo J-A, Lloyd CM, Kremer L, et al. (1996) Eosinophil recruitment to the lung in a murine model of allergic inflammation. J. Clin. Invest.98: 2332–2345. ArticleCASPubMedPubMed Central Google Scholar
Brusselle G, Kips J, Joos G, Bluethmann H, Pauwels R. (1995) Allergen-induced airway inflammation and bronchial responsiveness in wild-type and interleukin-4-deficient mice. Am. J. Respir. Cell Mol. Biol.12: 254–259. ArticleCASPubMed Google Scholar
Gavett SH, O’Hearn DJ, Karp CL, et al. (1997) Interleukin-4 receptor blockade prevents airway responses induced by antigen challenge in mice. Am. J. Physiol.272: L253–L261. PubMedCAS Google Scholar
Hogan SP, Mould A, Kikutani H, Ramsay AJ, Foster PS. (1997) Aeroallergen-induced eosinophilic inflammation, lung damage, and airways hyperreactivity in mice can occur independently of IL-4 and allergen-specific immunoglobulins. J. Clin. Invest.99: 1329–1339. ArticleCASPubMedPubMed Central Google Scholar
Kotsimbos TC, Ernst P, Hamid QA. (1996) Interleukin-13 and interleukin-4 are coexpressed in atopic asthma. Proc. Assoc. Am. Phys.108: 368–373. PubMedCAS Google Scholar
Kaplan MH, Schindler U, Smiley ST, Grusby MJ. (1996) Stat6 is required for mediating responses to IL-4 and for the development of Th2 cells. Immunity4: 313–319. ArticleCASPubMed Google Scholar
Rankin JA, Picarella DE, Geba GP, et al. (1996) Phenotypic and physiologic characterization of transgenic mice expressing interleukin 4 in the lung: Lymphocytic and eosinophilic inflammation without airway hyperreactivity. Proc. Natl. Acad. Sci. U.S.A.93: 7821–7825. ArticleCASPubMedPubMed Central Google Scholar
Drazen JM, Arm JP, Austen KF. (1996) Sorting out the cytokines of asthma. J. Exp. Med.183: 1–5. ArticleCASPubMed Google Scholar
Grunig G, Corry DB, Leach MW, Seymour BWP, Kurup VP, Rennick DM. (1997) Interleukin-10 is a natural suppressor of cytokine production and inflammation in a murine model of allergic bronchopulmonary aspergillosis. J. Exp. Med.185: 1089–1099. ArticleCASPubMedPubMed Central Google Scholar
Kitamura D, Roes J, Kuhn R, Rajewsky K. (1991) A B cell-deficient mouse by targeted disruption of the membrane exon of the immunoglobulin µ chain gene. Nature350: 423–426. ArticleCASPubMed Google Scholar
Mombaerts P, Iacomini J, Johnson RS, Herrup K, Tonegawa S, Papaioannou VE. (1992) RAG-1-deficient mice have no mature B and T lymphocytes. Cell68: 869–867. ArticleCASPubMed Google Scholar
Shinkai Y, Rathbun G, Lam K-P, et al. (1992) RAG-2-deficient mice lack mature lymphocytes owing to inability to initiate V(D)J rearrangement. Cell68: 855–867. ArticleCASPubMed Google Scholar
Kuhn R, Rajewsky K, Muller W. (1991) Generation and analysis of interleukin-4 deficient mice. Science254: 707–710. ArticleCASPubMed Google Scholar
Kopf M, Brombacher F, Hodgkin PD, et al. (1996) IL-5-deficient mice have a developmental defect in CD5+ B-1 cells and lack eosinophilia but have normal antibody and cytotoxic T cell responses. Immunity4: 15–24. ArticleCASPubMed Google Scholar
Kump VP, Ramasamy M, Greenberger PA, Fink JN. (1988) Isolation and characterization of a relevant Aspergillus fumigatus antigen with IgG- and IgE-binding activity. Int. Arch. Allergy Appl. Immunol.86: 176–182. Article Google Scholar
Schumacher JH, O’Garra A, Shrader B, et al. (1988) The characterization of four monoclonal antibodies specific for mouse IL-5 and development of mouse and human IL-5 enzyme-linked immunosorbent. J. Immunol.141: 1576–1581. PubMedCAS Google Scholar
Ohara J, Paul WE. (1985) Production of a monoclonal antibody to and molecular characterization of B cell stimulatory factor 1. Nature315: 333–336. ArticleCASPubMed Google Scholar
Korsgen M, Erjefalt JS, Korsgren O, Sundler F, Persson CGA. (1997) Allergic eosinophil-rich inflammation develops in lungs and airways of B cell-deficient mice. J. Exp. Med.185: 885–892. Article Google Scholar
Hamelmann EA, Vella T, Oshiba A, Kappler JW, Marrack P, Gelfand EW. (1997) Allergic airway sensitization induces T cell activation but not airway hyperresponsiveness in B cell-deficient mice. Proc. Natl. Acad. Sci. U.S.A.94: 1350–1355. ArticleCASPubMedPubMed Central Google Scholar
Shimura S, Andoh Y, Haraguchi M, Shirato K. (1996) Continuity of airway goblet cells and intraluminal mucus in the airways of patients with bronchial asthma. Eur. Respir. J.9: 1395–1401. ArticleCASPubMed Google Scholar
Bradding P, Feather IH, Howarth PH, et al. (1992) Interleukin 4 is localized to and released by human mast cells. J. Exp. Med.176: 1381–1386. ArticleCASPubMed Google Scholar
Broide DH, Paine MM, Firestein GS. (1992) Eosinophils express interleukin 5 and granulocyte macrophage-colony-stimulating factor mRNA at sites of allergic inflammation in asthmatics. J. Clin. Invest.90: 1414–1424. ArticleCASPubMedPubMed Central Google Scholar
Bradding P, Roberts JA, Britten KM, et al. (1994) Interleukin-4, −5, −6 and tumor necrosis factor-α in normal and asthmatic airways: Evidence for the human mast cell as a source of these cytokines. Am. J. Respir. Cell Mol. Biol.10: 471–480. ArticleCASPubMed Google Scholar
Burd PR, Thompson WC, Max EE, Mills FC. (1995) Activated mast cells produce interleukin 13. J. Exp. Med.181: 1373–1380. ArticleCASPubMed Google Scholar
Nonaka M, Nonaka R, Woolley K, et al. (1995) Distinct immunohistochemical localization of IL-4 in human inflammed airway tissues. J. Immunol.155: 3234–3244. PubMedCAS Google Scholar
Nakajima H, Gleich GJ, Kita H. (1996) Constitutive production of IL-4 and IL-10 and stimulated production of IL-8 by normal peripheral blood eosinophils. J. Immunol.156: 4859–4866. PubMedCAS Google Scholar
Moller GM, de Jong TAW, van der Kwast TH, et al. (1996) Immunolocalization of interleukin-4 in eosinophils in the bronchial mucosa of atopic asthmatics. Am. J. Respir. Cell Mol. Biol.14: 439–443. ArticleCASPubMed Google Scholar
Garssen J, Nijkamp FP, Van Der Vliet H, Van Loveren H. (1991) T-cell-mediated induction of airway hyperreactivity in mice. Am. Rev. Respir. Dis.144: 931–938. ArticleCASPubMed Google Scholar
Watanabe A, Mishima H, Renzi PM, Xu LJ, Hamid Q, Martin JG. (1995) Transfer of allergic airway responses with antigen-primed CD4+ but not CD8+ T cells in brown Norway rats. J. Clin. Invest.96: 1303–1310. ArticleCASPubMedPubMed Central Google Scholar
Oettgen HC, Martin TR, Wynshaw-Boris A, Deng CX, Drazen JM, Leder P. (1994) Active anaphylaxis in IgE-deficient mice. Nature370: 367–370. ArticleCASPubMed Google Scholar
Mehlhop PD, Van de Rijn M, Goldberg AB, et al. (1997) Allergen-induced bronchial hyperreactivity and eosinophilic inflammation occur in the absence of IgE in a mouse model of asthma. Proc. Natl. Acad. Sci. U.S.A.94: 1344–1349. ArticleCASPubMedPubMed Central Google Scholar
Coyle AJ, Wagner K, Bertrand C, Tsuyuki S, Bews J, Heusser C. (1996) Central role of immunoglobulin (Ig) E in the induction of lung eosinophil infiltration and T helper 2 cell cytokine production: Inhibition by a non-anaphylactogenic anti-IgE antibody. J. Exp. Med.183: 1303–1310. ArticleCASPubMed Google Scholar
Eum S-Y, Haile S, Lefort J, Huerre M, Vargaftig BB. 1995. Eosinophil recruitment into the respiratory epithelium following antigenic challenge in hyper-IgE mice is accompanied by interleukin 5-dependent bronchial hyperresponsiveness. Proc. Natl. Acad. Sci. U.S.A.92: 12290–12294. ArticleCASPubMedPubMed Central Google Scholar
Oshiba A, Hamelmann E, Takeda K, Bradley KL, Loader JE, Larsen GL, Gelfand EW. (1996) Passive transfer of immediate hypersensitivity and airway hyperresponsiveness by allergen-specific immunoglobulin (Ig) E and IgG1 in mice. J. Clin. Invest.97: 1398–1408. ArticleCASPubMedPubMed Central Google Scholar
Hamelmann E, Oshiba A, Schwarze J, et al. (1997) Allergen-specific IgE and IL-5 are essential for the development of airway hyperresponsiveness. Am. J. Respir. Cell Mol. Biol.16: 674–682. ArticleCASPubMed Google Scholar
Foster PS, Hogan SP, Ramsay AJ, Matthaei KI, Young IG. (1996) Interleukin 5 deficiency abolishes eosinophilia, airways hyperreactivity, and lung damage in a mouse asthma model. J. Exp. Med.183: 195–201. ArticleCASPubMed Google Scholar
Buijs J, Egbers MWEC, Lokhorst WH, Savelkoul HFJ, Nijkamp FP. (1995) Toxocara-induced eosinophilic inflammation. Airway function and effect of anti-IL-5. Am. J. Respir. Crit. Care Med.151: 873–878. ArticleCASPubMed Google Scholar
Bozic CR, Lu B, Hopken UE, Gerard C, Gerard NP. (1996) Neurogenic amplification of immune complex inflammation. Science273: 1722–1725. ArticleCASPubMed Google Scholar
Sylvestre DL, Ravetch JV. (1994) Fe receptors initiate the Arthus reaction: Redefining the inflammatory cascade. Science265: 1095–1098. ArticleCASPubMed Google Scholar
Jose PJ, Griffiths-Johnson DA, Collins PD, et al. (1994) Eotaxin: a potent eosinophil chemoattractant cytokine detected in a guinea pig model of allergic airways inflammation. J. Exp. Med.179: 881–887. ArticleCASPubMed Google Scholar
Gonzalo J-A, Jia G-Q, Aguirre V, et al. (1996) Mouse eotaxin expression parallels eosinophil accumulation during lung allergic inflammation but it is not restricted to a Th2-type response. Immunity 4: 1–14. ArticleCAS Google Scholar
Kita H, Gleich GJ. (1996) Chemokines active on eosinophils: Potential roles in allergic inflammation. J. Exp. Med.183: 2421–2426. ArticleCASPubMed Google Scholar
Rothenberg ME, MacLean JA, Pearlman E, Luster AD, Leder P. (1997) Targeted disruption of the chemokine eotaxin partially reduces antigen-induced tissue eosinophilia. J. Exp. Med.185: 785–790. ArticleCASPubMedPubMed Central Google Scholar
Stellato C, Collins P, Ponath PD, et al. (1997) Production of the novel C-C chemokine MCP-4 by airway cells and comparison of its biological activity to other C-C chemokines. J. Clin. Invest.99: 926–936. ArticleCASPubMedPubMed Central Google Scholar
Einarsson O, Geba GP, Zhu Z, Landry M, Elias JA. (1996) Interleukin-11: Stimulation in vivo and in vitro by respiratory viruses and induction of airways hyperresponsiveness. J. Clin. Invest.97: 915–924. ArticleCASPubMedPubMed Central Google Scholar
Nakajima H, Sano H, Nishimura T, Yoshida S, Iwamoto I. 1994. Role of vascular cell adhesion molecule 1/very late activation antigen 4 and intercellular adhesion molecule 1/lymphocyte function-associated antigen 1 interactions in antigen-induced eosinophil and T cell recruitment into the tissue. J. Exp. Med.179: 1145–1154. ArticleCASPubMed Google Scholar
Franklin W, Goetzl EJ. (1981) Total absence of eosinophils in a patient with an allergic disorder. Ann. Intern. Med.94: 352–353. ArticleCASPubMed Google Scholar
Juhlin L, Michaelsson G. (1977) A new syndrome characterized by absence of eosinophils and basophils. Lancet1: 1233–1235. ArticleCASPubMed Google Scholar
Lin RY, Lazarus TS. (1995) Asthma and related atopic disorders in outpatients attending an urban HIV clinic. Ann. Allergy Asthma Immunol.74: 510–515. PubMedCAS Google Scholar
Weiss KB, Gergen PJ, Hodgson TA. (1992) An economic evaluation of asthma in the United States. N. Engl. J. Med.326: 862–866. ArticleCASPubMed Google Scholar
Seaton A, Godden DJ, Brown K. (1994) Increase in asthma: A more toxic environment or a more susceptible population? Thorax49: 171–174. ArticleCASPubMedPubMed Central Google Scholar
Doull IJ, Lawrence S, Watson M, et al. (1996) Allelic association of gene markers on chromosomes 5q and llq with atopy and bronchial hyperresponsiveness. Am. J. Respir. Crit. Care Med.153: 1280–1284. ArticleCASPubMed Google Scholar
Daniels SE, Bhattacharrya S, James A, et al. (1996) A genome-wide search for quantitative trait loci underlying asthma. Nature383: 247–250. ArticleCASPubMed Google Scholar
Shirakawa T, Enomoto T, Shimazu S, Hopkin JM. (1997) The inverse association between tuberculin responses and atopic disorder. Science275: 77–79. ArticleCASPubMed Google Scholar