The Energetics of Membrane Fusion from Binding, through Hemifusion, Pore Formation, and Pore Enlargement (original) (raw)

• L.G. Abrahamyan R.M. Markosyan F.S. Moore J.P. Cohen G.B. Melikyan (2003)ArticleTitleHuman immunodeficiency virus type 1 Env with an intersubunit disulfide bond engages coreceptors but requires bond reduction after engagement to induce fusion_J. Virol_ 77 5829–5836Occurrence Handle10.1128/JVI.77.10.5829-5836.2003Occurrence Handle12719576
  Article PubMed Google Scholar
• R.T. Armstrong A.S. Kushnir J.M. White (2000)ArticleTitleThe transmembrane domain of influenza hemagglutinin exhibits a stringent length requirement to support the hemifusion to fusion transition_J. Cell Biol_ 151 425–438Occurrence Handle10.1083/jcb.151.2.425Occurrence Handle11038188
  Article PubMed Google Scholar
• A.L. Barnett R.A. Davey J.M. Cunningham (2001)ArticleTitleModular organization of the Friend murine leukemia virus envelope protein underlies the mechanism of infection_Proc. Natl. Acad. Sci. USA_ 98 4113–4118Occurrence Handle10.1073/pnas.071432398Occurrence Handle11274436
  Article PubMed Google Scholar
• J. Bentz A. Mittal (2003)ArticleTitleArchitecture of the influenza hemagglutinin membrane fusion site_Biochim. Biophys. Acta_ 1614 24–35Occurrence Handle12873763
  PubMed Google Scholar
• E. Borrego-Diaz M.E. Peeples R.M. Markosyan G.B. Melikyan F.S. Cohen (2003)ArticleTitleCompletion of trimeric hairpin formation of influenza virus hemagglutinin promotes fusion pore opening and enlargement_Virology_ 316 234–244Occurrence Handle10.1016/j.virol.2003.07.006Occurrence Handle14644606
  Article PubMed Google Scholar
• S. Bressanelli K. Stiasny S.L. Allison E.A. Stura S. Duquerroy J. Lescar F.X. Heinz F.A. Rey (2004)ArticleTitleStructure of a flavivirus envelope glycoprotein in its low-pH-induced membrane fusion conformation_EMBO J._ 23 728–738Occurrence Handle10.1038/sj.emboj.7600064Occurrence Handle14963486
  Article PubMed Google Scholar
• P.A. Bullough F.M. Hughson J.J. Skehel D.C. Wiley (1994)ArticleTitleStructure of influenza haemagglutinin at the pH of membrane fusion_Nature_ 371 37–43Occurrence Handle10.1038/371037a0Occurrence Handle8072525
  Article PubMed Google Scholar
• J. Cao L. Bergeron E. Helseth M. Thali H. Repke J. Sodoroski (1993)ArticleTitleEffects of amino acid changes in the extracellular domain of the human immunodeficiency virus type 1 gp41 envelope glycoprotein_J. Virol_ 67 2747–2755Occurrence Handle8474172
  PubMed Google Scholar
• C.M. Carr P.S. Kim (1993)ArticleTitleA spring-loaded mechanism for the conformational change of influenza hemagglutinin_Cell_ 73 823–832Occurrence Handle10.1016/0092-8674(93)90260-WOccurrence Handle8500173
  Article PubMed Google Scholar
• A. Chanturiya L.V. Chernomordik J. Zimmerberg (1997)ArticleTitleFlickering fusion pores comparable with initial exocytotic pores occur in protein-free phospholipid bilayers_Proc. Natl. Acad. Sci USA_ 94 14423–14428Occurrence Handle10.1073/pnas.94.26.14423Occurrence Handle9405628
  Article PubMed Google Scholar
• C.H. Chen T.J. Matthews C.B. McDanal M.L. Bolognesi D.P. Greenberg (1995)ArticleTitleA molecular clasp in the human immunodeficiency virus (HIV) type 1 TM protein determines the anti-HIV activity of gp41 derivatives: implication for viral fusion_J. Virol_ 69 3771–3777Occurrence Handle7538176
  PubMed Google Scholar
• J. Chen K.H. Lee D.A. Steinhauer D.J. Stevens J.J. Skehel D.C. Wiley (1998)ArticleTitleStructure of the hemagglutinin precursor cleavage site, a determinant of influenza pathogenicity and the origin of the labile conformation_Cell_ 95 409–417Occurrence Handle10.1016/S0092-8674(00)81771-7Occurrence Handle9814710
  Article PubMed Google Scholar
• J. Chen J.J. Skehel D.C. Wiley (1999)ArticleTitleN- and C-terminal residues combine in the fusion-pH influenza hemagglutinin HA(2) subunit to form an N cap that terminates the triple- stranded coiled coil_Proc. Natl. Acad. Sci. USA_ 96 8967–8972Occurrence Handle10.1073/pnas.96.16.8967Occurrence Handle10430879
  Article PubMed Google Scholar
• J. Chen S.A. Wharton W. Weisshborn L.J. Calder F.M. Hughson J.J. Skehel D.C. Wiley (1995)ArticleTitleA soluble domain of the membrane-anchoring chain of influenza virus hemagglutinin (HA2) folds in Escherichia coli into the low-pH-induced conformation_Proc. Natl. Acad. Sci. USA_ 92 12205–12209Occurrence Handle8618870
  PubMed Google Scholar
• L. Chernomordik M.M. KozIov J. Zimmerberg (1995)ArticleTitleLipids in biological membrane fusion_J. Membrane Biol_ 146 l–14Occurrence Handle10.1007/BF00232676
  Article Google Scholar
• L.V. Chernomordik V.A. Frolov E. Leikina P. Bronk J. Zimmerberg (1998)ArticleTitleThe pathway of membrane fusion catalyzed by influenza hemagglutinin: restriction of lipids, hemifusion, and lipidic fusion pore formation_J.Cell Biol_ 140 1369–1382Occurrence Handle10.1083/jcb.140.6.1369Occurrence Handle9508770
  Article PubMed Google Scholar
• L.V. Chernomordik M.M. KozIov (2003)ArticleTitleProtein-lipid interplay in fusion and fission of biological membranes_Annu Rev Biochem_ 72 175–207Occurrence Handle10.1146/annurev.biochem.72.121801.161504Occurrence Handle14527322
  Article PubMed Google Scholar
• L.V. Chernomordik G.B. Melikyan I.G. Abidor V.S. Markin Y.A. Chizmadzhev (1985)ArticleTitleThe shape of lipid molecules and monolayer membrane fusion_Biochim. Biophys Acta._ 812 643–655
  Google Scholar
• L.V. Chernomordik S.I. Sukharev S.V. Popov V.F. Pastushenko A.V. Sokirko I.G. Abidor Y.A. Chizmadzhev (1987)ArticleTitleThe electrical breakdown of cell and lipid membranes: the similarity of phenomenologies_Biochim. Biophys. Acta_ 902 360–373Occurrence Handle3620466
  PubMed Google Scholar
• Y.A. Chizmadzhev F.S. Cohen A. Shcherbakov J. Zimmerberg (1995)ArticleTitleMembrane mechanics can account for fusion pore dilation in stages_Biophys. J._ 69 2489–2500Occurrence Handle8599655
  PubMed Google Scholar
• Y.A. Chizmadzhev P.I. Kuzmin D.A. Kumenko J. Zimmerberg F.S. Cohen (2000)ArticleTitleDynamics of fusion pores connecting membranes of different tensions_Biophys. J._ 78 2241–2256Occurrence Handle10777723
  PubMed Google Scholar
• D.Z. Cleverley J. Lenard (1998)ArticleTitleThe transmembrane domain in viral fusion: essential role for a conserved glycine residue in vesicular stomatitis virus G protein_Proc. Natl. Acad. Sci. USA_ 95 3425–3430Occurrence Handle10.1073/pnas.95.7.3425Occurrence Handle9520382
  Article PubMed Google Scholar
• F.S. Cohen R.M. Markosyan G.B. Melikyan (2002)ArticleTitleThe process of membrane fusion: nipples, hemifusion, pores, and pore growth_Curr. Top. Membranes_ 52 501–529
  Google Scholar
• F.S. Cohen G.B. Melikyan (1998)ArticleTitleMethodologies in the study of cell-cell fusion_Methods_ 16 215–226Occurrence Handle10.1006/meth.1998.0670Occurrence Handle9790869
  Article PubMed Google Scholar
• P.M. Colman M.C. Lawrence (2003)ArticleTitleThe structural biology of type I viral membrane fusion_Nat. Rev. Mol. Cell Biol_ 4 309–319Occurrence Handle10.1038/nrm1076Occurrence Handle12671653
  Article PubMed Google Scholar
• K.J. Cross S.A. Wharton J.J. Skehel D.C. Wiley D.A. Steinhauer (2001)ArticleTitleStudies on influenza haemagglutinin fusion peptide mutants generated by reverse genetics_EMBO J._ 20 4432–4442Occurrence Handle10.1093/emboj/20.16.4432Occurrence Handle11500371
  Article PubMed Google Scholar
• J.W. Dubay S.J. Roberts B. Brody E. Hunter (1992)ArticleTitleMutations in the leucine zipper of the human immunodeficiency virus type 1 transmembrane glycoprotein affect fusion and infectivity_J. Virol_ 66 4748–4756Occurrence Handle1629954
  PubMed Google Scholar
• S.R. Durell I. Martin M. Ruysschaert Y. Shai R. Blumenthal (1997)ArticleTitleWhat studies of fusion peptides tell us about viral envelope glycoprotein-mediated membrane fusion (review)Mol. Membr. Biol. 14 97–112Occurrence Handle9394290
  PubMed Google Scholar
• R.F. Epand J.C. Macosko C.J. Russel Y.K. Shin R.M. Epand (1999)ArticleTitleThe ectodomain of HA2 of influenza virus promotes rapid pH dependent membrane fusion_J. Mol. Biol._ 286 489–503Occurrence Handle10.1006/jmbi.1998.2500Occurrence Handle9973566
  Article PubMed Google Scholar
• R.M. Epand R.F. Epand (2002)ArticleTitleThermal denaturation of influenza virus and its relationship to membrane fusion_Biochem. J._ 365 841–848Occurrence Handle11994048
  PubMed Google Scholar
• V. Frolov M. Cho T.S. Reese J. Zimmerberg (2000)ArticleTitleBoth hemifusion and fusion pores are induced by GPI-linked influenza hemagglutinin_Traffic_ 1 622–630Occurrence Handle10.1034/j.1600-0854.2000.010806.xOccurrence Handle11208150
  Article PubMed Google Scholar
• N. Fuller R.P. Rand (2001)ArticleTitleThe influence of lysolipids on the spontaneous curvature and bending elasticity of phospholipid membranes_Biophys. J._ 81 243–254Occurrence Handle11423410
  PubMed Google Scholar
• D.L. Gibbons I. Erk B. Reilly J. Navaza M. Kielian F. Rey J. Lepault (2003)ArticleTitleVisualization of the target-membrane-inserted fusion protein of Semliki Forest virus by combined electron microscopy and crystallography_Cell_ 114 573–583Occurrence Handle10.1016/S0092-8674(03)00683-4Occurrence Handle13678581
  Article PubMed Google Scholar
• D.L. Gibbons M.C. Vaney A. Roussel A. Vigouroux B. Reilly J. Lepault M. Kielian F.A. Rey (2004)ArticleTitleConformational change and protein-protein interactions of the fusion protein of Semliki Forest virus_Nature_ 427 320–325Occurrence Handle10.1038/nature02239Occurrence Handle14737160
  Article PubMed Google Scholar
• H. Hamm M. Kozlov (2000)ArticleTitleElastic energy of tilt and bending of fluid membranes_Eur. Phys. J._ 3 323–335
  Google Scholar
• M. Hamm M. Kozlov (1998)ArticleTitleTilt model of inverted amphipathic mesophases_Eur. Phys. J.B_ 6 519–528
  Google Scholar
• X. Han J.H. Bushweller D.S. Cafiso L.K. Tamm (2001)ArticleTitleMembrane structure and fusion-triggering conformational change of the fusion domain from influenza hemagglutinin_Nature Strurt. Biol._ 8 715–720Occurrence Handle10.1038/90434
  Article Google Scholar
• C. Harter P. James T. Bachi G. Semenza J. Brunner (1989)ArticleTitleHydrophobic binding of the ectodomain of influenza hemagglutinin to membranes occurs through the “fusion peptide”J. Biol. Chem. 264 6459–6464Occurrence Handle2703499
  PubMed Google Scholar
• C.A. Helm J.N. Israelachvilli P.M. McGuiggan (1992)ArticleTitleRole of hydrophobic forces in bilayer adhesion and fusion_Biochemistry_ 31 1794–1805Occurrence Handle10.1021/bi00121a030Occurrence Handle1737032
  Article PubMed Google Scholar
• L.D. Hernandez L.R. Hoffman T.G. Wolfsberg J.M. White (1996)ArticleTitleVirus-cell and cell-cell fusion_Annu. Rev. Cell. Dev. Biol._ 12 627–661Occurrence Handle8970739
  PubMed Google Scholar
• C. Hu M. Ahmed T.J. Melia T.H. Sollner T. Mayer J.E. Rothman (2003)ArticleTitleFusion of cells by flipped SNAREs_Science_ 300 1745–1749Occurrence Handle10.1126/science.1084909Occurrence Handle12805548
  Article PubMed Google Scholar
• J. Israelachvili R. Pashley (1982)ArticleTitleThe hydrophobic interaction is long range, decaying exponentially with distance_Nature_ 300 341–342Occurrence Handle10.1038/300341a0Occurrence Handle7144887
  Article PubMed Google Scholar
• R. Jahn T. Lang T.C. Sudhof (2003)ArticleTitleMembrane fusion_Cell_ 112 519–533Occurrence Handle10.1016/S0092-8674(03)00112-0Occurrence Handle12600315
  Article PubMed Google Scholar
• I. Jelesarov M. Lu (2001)ArticleTitleThermodynamics of trimer-of-hairpins formation by the SIV gp41 envelope protein_J. Mol. Biol._ 307 637–656Occurrence Handle10.1006/jmbi.2001.4469Occurrence Handle11254387
  Article PubMed Google Scholar
• H. Jin G.P. Leser R.A. Lamb (1994)ArticleTitleThe influenza virus hemagglutinin cytoplasmic tail is not essential for virus assembly or infectivity_EMBO J._ 13 5504–5515Occurrence Handle7957116
  PubMed Google Scholar
• G. Kemble T. Danieli J.M. White (1994)ArticleTitleLipid-anchored influenza hemagglutinin promotes hemifusion, not complete fusion_Cell_ 76 383–391Occurrence Handle10.1016/0092-8674(94)90344-1Occurrence Handle8293471
  Article PubMed Google Scholar
• G.W. Kemble Y.I. Henis J.M. White (1993)ArticleTitleGPI- and transmembrane-anchored influenza hemagglutinin differ in structure and receptor binding activity_J. Cell. Biol._ 122 1253–1265Occurrence Handle10.1083/jcb.122.6.1253Occurrence Handle8397215
  Article PubMed Google Scholar
• B. Kobe R.J. Center B.E. Kemp P. Poumbourios (1999)ArticleTitleCrystal structure of human T cell leukemia virus type 1 gp21 ectodomain crystallized as a maltose-binding protein chimera reveals structural evolution of retroviral transmembrane proteins_Proc. Natl. Acad. Sci. USA_ 96 4319–4324Occurrence Handle10.1073/pnas.96.8.4319Occurrence Handle10200260
  Article PubMed Google Scholar
• M.M. Kozlov V.S. Markin (1983)ArticleTitlePossible mechanism of membrane fusion_Biofizika_ 28 255–261
  Google Scholar
• Y. Kozlovsky L.V. Chernomordik M.M. Kozlov (2002)ArticleTitleLipid intermediates in membrane fusion: formation, structure, and decay of hemifusion diaphragm_Biophys. J._ 83 2634–2651Occurrence Handle12414697
  PubMed Google Scholar
• Y. Kozlovsky M.M. Kozlov (2002)ArticleTitleStalk model of membrane fusion: solution of energy crisis_Biophys. J._ 82 882–895Occurrence Handle11806930
  PubMed Google Scholar
• P.I. Kuzmin J. Zimmerberg Y.A. Chizmadzhev F.S. Cohen (2001)ArticleTitleA quantitative model for membrane fusion based on low-energy intermediates_Proc. Natl. Acad. Sci. USA_ 98 7235–7240Occurrence Handle10.1073/pnas.121191898Occurrence Handle11404463
  Article PubMed Google Scholar
• D. Leckband J. Israelachvili (2001)ArticleTitleIntermolecular forces in biology_Q. Rev. Biophys._ 34 105–267Occurrence Handle11771120
  PubMed Google Scholar
• J. Lee B.R. Lentz (1997)ArticleTitleEvolution of lipidic structures during model membrane fusion and the relation of this process to cell membrane fusion_Biochemistry_ 36 6251–6259Occurrence Handle10.1021/bi970404cOccurrence Handle9174340
  Article PubMed Google Scholar
• S. Leikin M.M. Kozlov N.L. Fuller R.P. Rand (1996)ArticleTitleMeasured effects of diacylglycerol on structural and elastic properties of phospholipid membranes_Biophys. J._ 71 2623–2632Occurrence Handle8913600
  PubMed Google Scholar
• S. Leikin V.A. Parsegian D.C Rau R.P Rand (1993)ArticleTitleHydration forces_Annu. Rev. Phys. Chem._ 44 369–395Occurrence Handle10.1146/annurev.pc.44.100193.002101Occurrence Handle8257560
  Article PubMed Google Scholar
• S.L. Leikin M.M. Kozlov L.V. Chernomordik V.S. Markin Y.A. Chizmadzhev (1987)ArticleTitleMembrane fusion: overcoming of the hydration barrier and local restructuring_J. Theor. Biol_ 129 411–425Occurrence Handle3455469
  PubMed Google Scholar
• E. Leikina D.L. LeDuc J.C. Macosko R. Epand Y.K. Shin L.V. Chernomordik (2001)ArticleTitleThe 1-127 HA2 construct of influenza virus hemagglutinin induces cell-cell hemifusion_Biochemistry_ 40 8378–8386Occurrence Handle10.1021/bi010466+Occurrence Handle11444985
  Article PubMed Google Scholar
• Y. Li X. Han L.K. Tamm (2003)ArticleTitleThermodynamics of fusion peptide-membrane interactions_Biochemistry_ 42 7245–7251Occurrence Handle10.1021/bi0341760Occurrence Handle12795621
  Article PubMed Google Scholar
• X. Lin C.A. Derdeyn R. Bluementhal J. West E. Hunter (2003)ArticleTitleProgressive truncations C terminal to the membrane-spanning domain of simian immunodeficiency virus Env reduce fusogenicity and increase concentration dependence of Env for fusion_J. Virol_ 77 7067–7077Occurrence Handle10.1128/JVI.77.12.7067-7077.2003Occurrence Handle12768026
  Article PubMed Google Scholar
• M. Lindau W. Almers (1995)ArticleTitleStructure and function of fusion pores in exocytosis and ectoplasmic membrane fusion_Curr. Opin. Cell. Biol._ 7 509–517Occurrence Handle10.1016/0955-0674(95)80007-7Occurrence Handle7495570
  Article PubMed Google Scholar
• M. Lu S.C. Blacklow P.S. Kim (1995)ArticleTitleA trimeric structural domain of the HIV-1 transmembrane glycoprotein_Nat. Struct. Biol._ 2 1075–1082Occurrence Handle10.1038/nsb1295-1075Occurrence Handle8846219
  Article PubMed Google Scholar
• M. Lu H. Ji S. Shen (1999)ArticleTitleSubdomain folding and biological activity of the core structure from human immunodeficiency virus type 1 gp41: implications for viral membrane fusion_J. Virol_ 73 4433–4438Occurrence Handle10196341
  PubMed Google Scholar
• M. Lu M.O. Stoller S. Wang J. Liu M.B. Fagan J.H. Numberg (2001)ArticleTitleStructural and functional analysis of interhelical interactions in the Human Immunodeficiency Virus type 1 gp41 envelope glycoprotein by alanine-scanning mutagenesis_J. Virol_ 75 11146–11156Occurrence Handle10.1128/JVI.75.22.11146-11156.2001Occurrence Handle11602754
  Article PubMed Google Scholar
• V.S. Markin J.P. Albanesi (2002)ArticleTitleMembrane fusion: stalk model revisited_Biophys. J._ 82 693–712Occurrence Handle11806912
  PubMed Google Scholar
• V.S. Markin M.M. Kozlov V.L. Borovjagin (1984)ArticleTitleOn the theory of membrane fusion_The stalk mechanism. Gen. Physiol. Biophys._ 3 361–377
  Google Scholar
• R.M. Markosyan F.S. Cohen G.B. Melikyan (2000)ArticleTitleThe lipid-anchored ectodomain of influenza virus hemagglutinin (GPI-HA) is capable of inducing nonenlarging fusion pores_Mol. Biol.Cell_ 11 1143–1152Occurrence Handle10749920
  PubMed Google Scholar
• R.M. Markosyan F.S. Cohen G.B. Melikyan (2003)ArticleTitleHIV-1 envelope proteins complete their folding into six-helix bundles immediately after fusion pore formation_Mol. Biol. Cell_ 14 926–938Occurrence Handle10.1091/mbc.E02-09-0573Occurrence Handle12631714
  Article PubMed Google Scholar
• R.M. Markosyan X. Ma M. Lu F.S. Cohen G.B. Melikyan (2002)ArticleTitleThe mechanism of inhibition of HIV-1 env-mediated cell-cell fusion by recombinant cores of gp41 ectodomain_Virology_ 302 174–184Occurrence Handle10.1006/viro.2002.1593Occurrence Handle12429526
  Article PubMed Google Scholar
• I. Markovic E. Leikina M. Zhukovsky J. Zimmerberg L.V. Chernomordik (2001)ArticleTitleSynchronized activation and refolding of influenza hemagglutinin in multimeric fusion machines_J. Cell. Biol._ 155 833–844Occurrence Handle10.1083/jcb.200103005Occurrence Handle11724823
  Article PubMed Google Scholar
• S. May (2002)ArticleTitleStructure and energy of fusion stalks: the role of membrane edges_Biophys. J._ 83 2969–2980Occurrence Handle12496070
  PubMed Google Scholar
• G.B. Melikyan S.A. Brener D.C. Ok F.S. Cohen (1997)ArticleTitleInner but not outer membrane leaflets control the transition from glycosylphosphatidylinositol-anchored influenza hemagglutinin-induced hemifusion to full fusion_J. Cell. Biol._ 136 995–1005Occurrence Handle10.1083/jcb.136.5.995Occurrence Handle9060465
  Article PubMed Google Scholar
• G.B. Melikyan H. Jin R.A. Lamb F.S. Cohen (1997)ArticleTitleThe role of the cytoplasmic tail region of influenza virus hemagglutinin in formation and growth of fusion pores_Virology_ 235 118–128Occurrence Handle10.1006/viro.1997.8686Occurrence Handle9300043
  Article PubMed Google Scholar
• G.B. Melikyan S. Lin M.G. Roth F.S. Cohen (1999)ArticleTitleAmino acid sequence requirements of the transmembrane and cytoplasmic domains of influenza virus hemagglutinin for viable membrane fusion_Mol. Biol. Cell_ 10 1821–1836Occurrence Handle10359599
  PubMed Google Scholar
• G.B. Melikyan R.M. Markosyan H. Hemmati M.K. Delmedico D.M Lambert F.S. Cohen (2000)ArticleTitleEvidence that the transition of HIV-1 gp41 into a six-helix bundle, not the bundle configuration, induces membrane fusion_J. Cell. Biol._ 151 413–424Occurrence Handle10.1083/jcb.151.2.413Occurrence Handle11038187
  Article PubMed Google Scholar
• G.B. Melikyan R.M. Markosyan M.G. Roth F.S. Cohen (2000)ArticleTitleA point mutation in the transmembrane domain of the hemagglutinin of influenza virus stabilizes a hemifusion intermediate that can transit to fusion_Mol. Biol Cell_ 11 3765–3775Occurrence Handle11071905
  PubMed Google Scholar
• G.B. Melikyan J.M. White F.S. Cohen (1995)ArticleTitleGPI-anchored influenza hemagglutinin induces hemifusion to both red blood cell and planar bilayer membranes_J. Cell_ 131 679–691Occurrence Handle10.1083/jcb.131.3.679
  Article Google Scholar
• A. Mittal E. Leikina L.V. Chernomordik J. Bentz (2003)ArticleTitleKinetically differentiating influenza hemagglutinin fusion and hemifusion machines_Biophys J._ 85 1713–1724Occurrence Handle12944286
  PubMed Google Scholar
• Y. Modis S. Ogata D. Clements S.C. Harrison (2004)ArticleTitleStructure of the dengue virus envelope protein after membrane fusion_Nature_ 427 313–319Occurrence Handle10.1038/nature02165Occurrence Handle14737159
  Article PubMed Google Scholar
• M. Muller K. Katsov M. S chick (2003)ArticleTitleA new mechanism of model membrane fusion determined from Monte Carlo simulation_Biophys. J._ 85 1611–1623Occurrence Handle12944277
  PubMed Google Scholar
• I. Munoz-Barroso S. Durell K. Sakaguchi E. Appella R. Blumenthal (1998)ArticleTitleDilation of the human immunodeficiency virus- 1 envelope glycoprotein fusion pore revealed by the inhibitory action of a synthetic peptide from gp41_J. Cell. Biol._ 140 315–323Occurrence Handle10.1083/jcb.140.2.315Occurrence Handle9442107
  Article PubMed Google Scholar
• I. Munoz-Barroso K. Salzwedel E. Hunter R. Blumenthal (1999)ArticleTitleRole of the membrane-proximal domain in the initial stages of human immunodeficiency virus type 1 envelope glycoprotein-mediated membrane fusion_J. Virol._ 73 6089–6092Occurrence Handle10364363
  PubMed Google Scholar
• E. Neher (1974)ArticleTitleAsymmetric membranes resulting from the fusion of two black lipid bilayers_Biochim. Biophys. Acta._ 373 327–336Occurrence Handle4139977
  PubMed Google Scholar
• H. Noguchi M. Takasu (2001)ArticleTitleFusion pathways of vesicles: A Brownian dynamics simulation_J. Chem. Phys._ 115 9547–9551Occurrence Handle10.1063/1.1414314
  Article Google Scholar
• F. Nüssler M.J. Clague A. Herrmann (1997)ArticleTitleMeta-stability of the hemifusion intermediate induced by glycosylphosphatidylinositol-anchored influenza hemagglutinin_Biophys. J._ 173 2280–2291
  Google Scholar
• D. Odell E. Wanas J. Yan H.P. Ghosh (1997)ArticleTitleInfluence of membrane anchoring and cytoplasmic domains on the fusogenic activity of vesicular stomatitis virus glycoprotein G_J. Virol._ 71 7996–8000Occurrence Handle9311894
  PubMed Google Scholar
• C.C. Pak A. Puri R. Blumenthal (1997)ArticleTitleConformational changes and fusion activity of vesicular stomatitis virus glycoprotein: [125I] iodonaphthyl azide photolabeling studies in biological membranes_Biochemistry_ 36 8890–8896Occurrence Handle10.1021/bi9702851Occurrence Handle9220976
  Article PubMed Google Scholar
• D.P. Pantazatos S.P. Pantazatos R.C. MacDonald (2003)ArticleTitleBilayer mixing, fusion, and lysis following the interaction of populations of cationic and anionic phospholipid bilayer vesicles_J. Membrane Biol._ 194 129–139Occurrence Handle10.1007/s00232-003-2031-y
  Article Google Scholar
• H.E. Park J.A. Gruenke J.M. White (2003)ArticleTitleLeash in the groove mechanism of membrane fusion_Nat. Struct. Biol._ 10 1048–1053Occurrence Handle10.1038/nsb1012Occurrence Handle14595397
  Article PubMed Google Scholar
• V.A. Parsegian R.P. Rand D. Gingell (1984)ArticleTitleLessons for the study of membrane fusion from membrane interactions in phospholipid systems_Ciba Found. Symp._ 103 9–27Occurrence Handle6561140
  PubMed Google Scholar
• E.I. Pecheur D. Hoekstra J. Sainte-Marie L. Maurin A. Bienvenue J.R. Philippot (1997)ArticleTitleMembrane anchorage brings about fusogenic properties in a short synthetic peptide_Biochemistry_ 36 3773–3781Occurrence Handle10.1021/bi9622128Occurrence Handle9092806
  Article PubMed Google Scholar
• H. Qiao R.T. Armstrong G.B. Melikyan F.S. Cohen J.M. White (1999)ArticleTitleA specific point mutant at position 1 of the influenza hemagglutinin fusion peptide displays a hemifusion phenotype_Mol. Biol. Cell_ 10 2759–2769Occurrence Handle10436026
  PubMed Google Scholar
• D. Rapaport Y. Shai (1994)ArticleTitleInteraction of fluorescently labeled analogues of the amino-terminal fusion peptide of Sendai virus with phospholipid membranes_J. Biol. Chem._ 269 15124–15131Occurrence Handle8195149
  PubMed Google Scholar
• W. Rawicz K.C. Olbrich T. McIntosh D. Needham E. Evans (2000)ArticleTitleEffect of chain length and unsaturation on elasticity of lipid bilayers_Biophys. J._ 79 328–339Occurrence Handle10866959
  PubMed Google Scholar
• V. Razinkov G.B. Melikyan F.S. Cohen (1999)ArticleTitleHemifusion between cells expressing hemagglutinin (HA) of influenza virus and planar membranes can precede the formation of fusion pores that subsequently fully enlarge_Biophys. J._ 77 3144–3151Occurrence Handle10585935
  PubMed Google Scholar
• D.P. Remeta M. Krumbiegel C.A. Minetti A. Puri A. Ginsburg R. Blumenthal (2002)ArticleTitleAcid-induced changes in thermal stability and fusion activity of influenza hemagglutinin_Biochemistry_ 41 2044–2054Occurrence Handle10.1021/bi015614aOccurrence Handle11827552
  Article PubMed Google Scholar
• C.J. Russell T.S. Jardetzky R.A. Lamb (2001)ArticleTitleMembrane fusion machines of paramyxoviruses: capture of intermediates of fusion_EMBO J._ 20 4024–4034Occurrence Handle10.1093/emboj/20.15.4024Occurrence Handle11483506
  Article PubMed Google Scholar
• K. Sackett Y. Shai (2003)ArticleTitleHow structure correlates to function for membrane associated HIV-1 gp41 constructs corresponding to the N-terminal half of the ectodomain_J. Mol. Biol._ 333 47–58Occurrence Handle10.1016/j.jmb.2003.07.008Occurrence Handle14516742
  Article PubMed Google Scholar
• C. Schoch R. Blumenthal (1993)ArticleTitleRole of the fusion peptide sequence in initial stages of influenza hemagglutinin-induced cell fusion_J. Biol. Chem._ 268 9267–9274Occurrence Handle8387488
  PubMed Google Scholar
• M.P. Sheetz S.J. Singer (1974)ArticleTitleBiological membranes as bilayer couples_A molecular mechanism of drug-erythrocyte interactions. Proc. Natl. Acad. Sci. USA_ 71 4457–4461
  Google Scholar
• D.P. Siegel (1993)ArticleTitleEnergetics of intermediates in membrane fusion: comparison of stalk and inverted micellar intermediate mechanisms_Biophys. J._ 65 2124–2140Occurrence Handle8298039
  PubMed Google Scholar
• D.P. Siegel (1999)ArticleTitleThe modified stalk mechanism of lamellar/inverted phase transitions and its implications for membrane fusion_Biophys. J._ 76 291–313Occurrence Handle9876142
  PubMed Google Scholar
• J.J. Skehel D.C. Wiley (1998)ArticleTitleCoiled coils in both intracellular vesicle and viral membrane fusion_Cell_ 95 871–874Occurrence Handle10.1016/S0092-8674(00)81710-9Occurrence Handle9875840
  Article PubMed Google Scholar
• T. Stegmann J.M. Delfino F.M. Richards A. Helenius (1991)ArticleTitleThe HA2 subunit of influenza hemagglutinin inserts into the target membrane prior to fusion_J. Biol.Chem._ 266 18404–18410Occurrence Handle1917964
  PubMed Google Scholar
• T. Stegmann R.W. Doms (1989)ArticleTitleProtein-mediated membrane fusion_Annu, Rev. Biophys. Biophys. Chem._ 18 187–211
  Google Scholar
• J.A. Szule N.L. Fuller R.P. Rand (2002)ArticleTitleThe effects of acyl chain length and saturation of diacylglycerols and phosphatidylcholines on membrane monolayer curvature_Biophys. J._ 83 977–984Occurrence Handle12124279
  PubMed Google Scholar
• S.A. Tatulian P. Hinterdorfer G. Baber L.K. Tamm (1995)ArticleTitleInfluenza hemagglutinin assumes a tilted conformation during membrane fusion as determined by attenuated total reflection FTIR spectroscopy_EMBO J._ 14 5514–5523Occurrence Handle8521808
  PubMed Google Scholar
• G.M. Taylor D.A. Sanders (1999)ArticleTitleThe role of the membrane-spanning domain sequence in glycoprotein-mediated membrane fusion_Mol. Biol. Cell_ 10 2803–2815Occurrence Handle10473628
  PubMed Google Scholar
• F.W. Tse A. Iwata W. Almers (1993)ArticleTitleMembrane flux through the pore formed by a fusogenic viral envelope protein during cell fusion_J. Cell Biol._ 121 543–552Occurrence Handle10.1083/jcb.121.3.543Occurrence Handle8486735
  Article PubMed Google Scholar
• Y. Weng Z. Yang C.D. Weiss (2000)ArticleTitleStructure- function studies of the self-assembly domain of the human immunodeficiency virus type 1 transmembrane protein gp41_J. Virol._ 74 5368–5372Occurrence Handle10.1128/JVI.74.11.5368-5372.2000Occurrence Handle10799616
  Article PubMed Google Scholar
• J.M. White I.A. Wilson (1987)ArticleTitleAnti-peptide antibodies detect steps in a protein conformational change: low-pH activation of the influenza virus hemagglutinin_J. Cell. Biol._ 105 2887–2896Occurrence Handle10.1083/jcb.105.6.2887Occurrence Handle2447101
  Article PubMed Google Scholar
• C.T. Wild D.C. Shugars T.K. Greenwell C.B. McDanal T.J. Matthews (1994)ArticleTitlePeptides corresponding to a predictive alpha-helical domain of human immunodeficiency virus type 1 gp41 are potent inhibitors of virus infection_Proc. Natl. Acad. Sci. USA_ 91 9770–9774Occurrence Handle7937889
  PubMed Google Scholar
• T. Wilk T. Pfeiffer A. Bukovsky G. Moldenhauer V. Bosch (1996)ArticleTitleGlycoprotein incorporation and HIV-1 infectivity despite exchange of the gp160 membrane-spanning domain_Virology_ 218 269–274Occurrence Handle10.1006/viro.1996.0190Occurrence Handle8615034
  Article PubMed Google Scholar
• I.A. Wilson J.J. Skehel D.C. Wiley (1981)ArticleTitleStructure of the haemagglutinin membrane glycoprotein of influenza virus at 3Å resolution_Nature_ 289 366–373Occurrence Handle10.1038/289366a0Occurrence Handle7464906
  Article PubMed Google Scholar
• L. Yang L. Ding H.W. Huang (2003)ArticleTitleNew phases of phospholipids and implications to the membrane fusion problem_Biochemistry_ 42 6631–6635Occurrence Handle10.1021/bi0344836Occurrence Handle12779317
  Article PubMed Google Scholar
• L. Yang H.W. Huang (2002)ArticleTitleObservation of a membrane fusion intermediate structure_Science_ 297 1877–1879Occurrence Handle10.1126/science.1074354Occurrence Handle12228719
  Article PubMed Google Scholar
• T. Zavorotinskaya Z. Qian J. Franks L.M. Albritton (2004)ArticleTitleA point mutation in the binding subunit of a retroviral envelope protein arrests virus entry at hemifusion_J. Virol._ 78 473–481Occurrence Handle10.1128/JVI.78.1.473-481.2004Occurrence Handle14671127
  Article PubMed Google Scholar
• J. Zimmerberg R. Blumenthal D.P. Sarkar M. Curran S.J. Morris (1994)ArticleTitleRestricted movement of lipid and aqueous dyes through pores formed by influenza hemagglutinin during cell fusion_J. Cell. Biol._ 127 1885–1894Occurrence Handle10.1083/jcb.127.6.1885Occurrence Handle7806567
  Article PubMed Google Scholar