Non-infantile variant of desmoplastic ganglioglioma: a report of 2 cases (original) (raw)
Abstract
Desmoplastic infantile gangliogliomas (DIGs) are uncommon supratentorial brain tumors with a usually good prognosis despite an aggressive radiological appearance. These tumors form part of a spectrum of desmoplastic infantile tumors that includes desmoplastic infantile astrocytomas. DIGs are classified as benign WHO grade I tumors of infancy. Non-infantile variants of this biologically benign intracranial neoplasm are rare, with only four previous case reports in the literature. We report two cases of non-infantile DIG diagnosed at our institution on the basis of clinical features, radiological appearance and histological findings.
Access this article
Subscribe and save
- Get 10 units per month
- Download Article/Chapter or eBook
- 1 Unit = 1 Article or 1 Chapter
- Cancel anytime Subscribe now
Buy Now
Price excludes VAT (USA)
Tax calculation will be finalised during checkout.
Instant access to the full article PDF.
Similar content being viewed by others
References
- Trehan G, Bruge H, Vinchon M, et al (2004) MR imaging in the diagnosis of desmoplastic infantile tumor: retrospective study of six cases. AJNR 25:1028–1033
PubMed Google Scholar - Taratuto AL, Monges J, Lylyk P, et al (1984) Superficial cerebral astrocytoma attached to dura: report of six cases in infants. Cancer 54:2505–2512
Article PubMed CAS Google Scholar - VandenBerg SR, May EE, Rubinstein LJ, et al (1987) Desmoplastic supratentorial neuroepithelial tumors of infancy with divergent differentiation potential (“desmoplastic infantile gangliogliomas”): report of 11 cases of a distinctive embryonal tumor with favorable prognosis. J Neurosurg 66:58–71
Article PubMed CAS Google Scholar - Marti A, Almostarchid B, Maher M, et al (2000) Desmoplastic non-infantile ganglioglioma. Case report. J Neurosurg Sci 44:150–154
PubMed CAS Google Scholar - Taratuto AL, VandenBerg SR, Rorke LB, et al (2000) Desmoplastic infantile astrocytoma and ganglioglioma. In: Kleihues P, Cavenee WK (eds) Pathology and genetics: tumors of the nervous system. IRC Press, Lyon, France, pp 99–102
Google Scholar - Galatioto S, Gullotta F (1996) Desmoplastic non-infantile ganglioglioma. J Neurosurg Sci 40:235–238
PubMed CAS Google Scholar - Kuchelmeister K, Bergmann M, von Wild K, et al (1993) Desmoplastic ganglioglioma: a report of two non-infantile cases. Acta Neuropathol (Berlin) 85:199–204
Article CAS Google Scholar - Craver RD, Nadell J, Nelson JS, et al (1999) Desmoplastic infantile ganglioglioma. Pediatr Dev Pathol 2:582–587
Article PubMed CAS Google Scholar - De Munnynck K, Van Gool S, Van Calenbergh F, et al (2002) Desmoplastic infantile ganglioglioma: a potential malignant tumor? Am J Surg Pathol 26:1515–1522
Article PubMed Google Scholar
Editorial note added in proof.
In addition to the following list of references, authors are also referred to: Kesavadas C, Sonwalker H, Thomas B, et al. (2005) Atypical MRI appearance of desmoplastic infantile ganglioglioma. Pediatr Radiol 35:1024–1026
Author information
Authors and Affiliations
- Department of CT and MRI, Jaslok Hospital and Research Centre, 15, Dr. G. Deshmukh Marg, Mumbai 400026, Maharashtra, India
Karthik Ganesan & Shrinivas Desai - Department of Neurology, Jaslok Hospital and Research Centre, Maharashtra, India
Anaita Udwadia-Hegde
Authors
- Karthik Ganesan
You can also search for this author inPubMed Google Scholar - Shrinivas Desai
You can also search for this author inPubMed Google Scholar - Anaita Udwadia-Hegde
You can also search for this author inPubMed Google Scholar
Corresponding author
Correspondence toKarthik Ganesan.
Rights and permissions
About this article
Cite this article
Ganesan, K., Desai, S. & Udwadia-Hegde, A. Non-infantile variant of desmoplastic ganglioglioma: a report of 2 cases.Pediatr Radiol 36, 541–545 (2006). https://doi.org/10.1007/s00247-005-0095-9
- Received: 10 October 2005
- Revised: 05 December 2005
- Accepted: 08 December 2005
- Published: 22 March 2006
- Issue Date: June 2006
- DOI: https://doi.org/10.1007/s00247-005-0095-9