Construction and characterization of the chimeric monoclonal antibody E48 for therapy of head and neck cancer (original) (raw)

References

  1. Bader CC, Krohn KA, Bernstein ID (1987) In vitro measurement of avidity of radioiodinated antibodies. Int J Radiat Appl Instrum 14:605
    Google Scholar
  2. Brakenhoff RH, Geurts van Kessel AHM, Oldenburg M, Wijnen JTh, Bloemendal H, Meera Khan P, Schoenmakers JGG (1990) Human αB-crystallin (CRYA2) gene mapped to chromosome 11q12-q23. Hum Genet 85:237
    PubMed Google Scholar
  3. Caton AJ, Brownlee GG, Staudt LM, Gerhard W (1986) Structural and functional impications of a restricted antibody response to a defined antigenic redgion on the influenza virus hemagglutinin. EMBO J 56:1577
    Google Scholar
  4. Cheung NKV, Lazarus H, Miraldi FD, Abramowsky CR, Kallick S, Saarinen UM, Spitser T, Strandjord SE, Coccia PF, Berger NA (1987) Ganglioside GD2 specific monoclonal antibody 3F8: a phase I study in patients with neuroblastoma and malignant melanoma. J. Clin Oncol 5:1430
    PubMed Google Scholar
  5. Courtenay-Luck NS, Epenetos AA, Moore R, Larche M, Pectaside D, Dhokia B, Ritter MA (1986) Development of primary and secondary immune responses to mouse monoclonal antibodies used in diagnosis and therapy of malignant neoplasms. Cancer Res 46:6489
    PubMed Google Scholar
  6. De Bree R, Roos JC, Quak JJ, Den Hollander W, Van den Brekel MWM, Van de Wal JE, Tobi H, Snow GB, Van Dongen GAMS (1994) Clinical imaging of head and neck cancer with99mTc-labeled monoclonal antibody E48 IgG or F(ab')2. J Nucl Med 35:775
    PubMed Google Scholar
  7. Feinberg AP, Vogelstein B (1988) A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity. Anal Biochem 132:6
    Google Scholar
  8. Gerretsen M, Quak JJ, Suh JS, Van Walsum, Meijer CJLM, Snow GB, Van Dongen GAMS (1991) Superior localisation of monoclonal antibody E48 F(ab')2 fragment in xenografts of human squamous cell carcinoma of the head and neck and of the vulva as compared to monoclonal antibody E48 IgG. Br J Cancer 63:37
    PubMed Google Scholar
  9. Gerretsen M, Schrijvers AHGJ, Van Walsum M, Braakhuis BJM, Snow GB, Van Dongen GAMS (1992) Radioimmunothraphy of head and neck squamous cell carcinoma with131I-labeled monoclonal antibody E48. Br J Cancer 66:496
    PubMed Google Scholar
  10. Gerretsen M, Visser GWM, van Walsum M, Meijer CJLM, Snow GB, Van Dongen GAMS (1993)186Re-labeled monoclonad antibody E48 IgG mediated therapy of human head and neck squamous cell carcinoma xenografts. Cancer Res 53:3524
    PubMed Google Scholar
  11. Gerretsen M, Visser GWM, Brakenhoff RH, Snow GB, Van Dongen GAMS (1994) Complete ablation of small human head and neck squamous cell carcinoma xenografts with186Relabeled monoclonal antibody E48 IgG. Cell Biophys 24:1
    Google Scholar
  12. Gough NM (1988) Rapid and quantitative preparation of cytoplasmic RNA from small numbers of cells. Anal Biochem 173:93
    PubMed Google Scholar
  13. Herlyn D, Koprowski H (1982) IgG2a monoclonal antibodies inhibit human tumor growth through interaction with effector cells. Proc Natl Acad Sci USA 79:4761
    PubMed Google Scholar
  14. Huse WD, Sastry L, Iverson SA, Kang AS, Alting-Mees M, Burton DR, Benkovic SJ, Lerner RA (1989) Generation of a large combinatorial library of the immunoglobulin repretoire in phage lambda. Science 246:1275
    PubMed Google Scholar
  15. Janson CH, Tehrani M, Wigzell (1989) Rational use of biological response modifiers in hematological malignancies: a review of treatment with interfron, cytotoxic cells and antibodies. Leuk Res 13:1039
    PubMed Google Scholar
  16. Jones PT, Dear PH, Foote J, Neuberger MS, Winter G (1986) Replacing the complementarity-determining regions in a human antibody with those from a mouse. Nature 321:522
    PubMed Google Scholar
  17. Kavaler J, Caton AJ, Staudt LM, Schwartz D, Gerhard W (1990) A set of closely related antibodies dominates the primary antibody response to the antigenic site CB of the A/PR/8/34 influenza virus hemagglutinin. J Immunol 145:2312
    PubMed Google Scholar
  18. Khazaeli MB, Conry R, LoBuglio AF (1994) Human immune response to monoconal antibodies. J Immunother 15:42
    PubMed Google Scholar
  19. Laemmli UK (1970) Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 227:680
    PubMed Google Scholar
  20. LoBuglio AF, Wheeler RH, Trang J, Haynes A, Rogers K, Harvey EB, Sun L, Grayeb J, Khazaeli MB (1989) Mouse/human chimeric monoclonal antibody in man: kinetics and immune response. Proc. Natl Acad Sci USA 86:4220
    PubMed Google Scholar
  21. LoBuglio AF, Khazaeli MB, Meredith R, Saleh MN (1992) Chimeric monoclonal antibodies in cancer theraphy In: NDDO EORTC (ed) Proceedings of the 7th NCI-EORTC symposium on new drugs in cancer therapy. Free Univ. Press, Amsterdam, March. p 196
    Google Scholar
  22. Looney JE, Knight DM, Arevalo-Moore M, Trinh H, Pak K-Y, Dalesandro MR, Rieber EP, Riethmüller G, Daddona PE, Ghrayeb J (1992) High-level expression and characterization of a mouse-human chimeric CD4 antibody with therapeutic potential. Hum Antibody Hybridomas 3:191
    Google Scholar
  23. Massagur LFAG, Thomas CMG, Segers MFG, Corstens FHM, Verheijen RHM, Kenemans P, Poels LG (1992) Specific and nonspecific immunoassays to detect HAMA after administration of indium-111-labeled OV-TL-3 F(ab')2 monoclonal antibody to patients with ovarian cancer. J Nucl Med 33:1958
    PubMed Google Scholar
  24. Meredith RF, LoBuglio AF, Plott WE, Orr RA, Brezovich IA, Russell CD, Harvey EB, Yester MV, Wagner AJ, Spencer SA (1991) Pharmacokinetics, immune response, and biodistribution of iodine-131-labeled chimeric mouse/human IgG, κ 17-1A monoclonal antibody. J Nucl Med 32:1162
    PubMed Google Scholar
  25. Morrison SL, Johson MJ, Herzenberg LA, Oi VT (1984) Chimeric human antibody molecules: mouse antigen-binding domains with human constant region domains. Proc Natl Acad Sci USA 81:6851
    PubMed Google Scholar
  26. Quak JJ, Van Dongen GAMS, Balm AJM, Brakkee JPG, Scheper RJ, Snow GB, Meijer CJLM (1990) A 22-kDa surface antigen detected by monoclonal antibody E48 is exclusively expressed in stratified squamous and transitional epithelia. Am J Pathol 136:191
    PubMed Google Scholar
  27. Quak JJ, Van Dongen GAMS, Gerretsen M, Hayashida D, Balm AJM, Brakkee JPG, Snow GB, Meijer CJLM (1990) Production of monoclonal antibody (K931) to a squamous cell carcinoma antigen identified as the 17-1A antigen. Hybridoma 9:377
    PubMed Google Scholar
  28. Quak JJ, Schrijvers AHGJ, Brakkee JGP, Davis HD, Scheper RJ Balm AJM, Meijer CJLM, Snow GB, Van Dongen GAMS (1992) Expression and characterization of two differentiation antigens in stratified squamous epithelia and carcinomas. Int J Cancer 50:507
    PubMed Google Scholar
  29. Ragnhammer P, Fagerberg J, Frödin J-E, Hjelm A-L, Lindemalm C, Magnusson I, Masucci G, Mellstedt H, (1993) Effect of monoclonal antibody 17-1A and GM-CSF in patients with advanced colorectal carcinoma: long lasting, complete remissions can be induced. Int J Cancer 53:751
    PubMed Google Scholar
  30. Reynolds JC, Del Vecchio S, Sakahara H, Lora ME, Carrasquillo JA, Neumann RD, Larson SM (1989) Anti-murine respponse to mouse monoclonal antibodies: clinical findings and implications. Nucl Med Biol 16:121
    Google Scholar
  31. Riethmüller G, Schneider-Gadicke E, Schlimok G, Schmieldel W, Raab R, Hofken K, Gruber R, Pichlmaier H, Hirche H, Pichlmaier R, Buggisch P, Witte J (1994) Randomised trial of monoclonal antibody for adjuvant theraphy of resected Dukes'C colorectal carcinoma. Lancet 343:1177
    PubMed Google Scholar
  32. Sambrook J, Fritsch EF, Maniatis T (1989) Molecular cloning: a laboratory manual, 2nd edn. Cold Spring Harbor Laboratory, Cold Spring Harbor, New York
    Google Scholar
  33. Schrijvers AHGJ, Gerretsen M, Fritz J, Van Walsum M, Quak JJ, Snow GB, Van Dongen GAMS (1991) Evidence for a role of the monoclonal antibody E48 defined antigen in cell-cell adhesion in squamous epithelia and head and neck squamous cell carcinomas. Exp Cell Res 196:264
    PubMed Google Scholar
  34. Seybold K, Trinkler M, Frey LD, Locher JT (1994) Long-term HAMA-follow up after immunoscintigraphy using antigranulocyte and anti-tumour mAbs: advanced experiences in 210 patients. In: Lind P (ed) Proceedings of the 9th Annual Meeting of the International Research Group on Immunoscintigraphy and Immunotheraphy. Klagen furt, Austria, p 28
    Google Scholar
  35. Steplewski Z, Sun LK, Shearman CW, Ghrayeb J, Donnadona P and Koprowski H (1988) Biological activity of human-mouse IgG1, IgG2, IgG3, and IgG4 chimeric monoclonal antibodies with antitumor specificity. Proc Natl Acad Sci USA 85:4852
    PubMed Google Scholar
  36. Steplewski Z, Lubeck MD, Scholz H, Loibner J, McDonald Smith, Koprowski H (1991) Tumor cell lysis and tumor growth inhibiton by the isotype variants of mAb Br 55-2 directed against Y oloigosaccharide. In Vivo 5:79
    PubMed Google Scholar
  37. Van Dongen GAMS, Leverstein H, Roos JC, Quak JJ, Brekel M van den, Lingen A van, Martens HJM, Castelijns J, Visser GWM, Meijer CJLM, Teule JJ, Snow GB (1992) Radioimmujnoscintigraphy of head and neck tumors using99mTclabeled monoclonal antibody E48 F(ab')2 Cancer Res 52:2569
    PubMed Google Scholar
  38. Van Dongen GAMS, Brakenhoff RH, De Bree R, Gerretsen M, Quak JJ, Snow GB (1994) Progress in radioimmuotherapy of head and neck cancer: review. Oncol Rep 1:259
    Google Scholar
  39. Visser G, Gerretsen M, Herscheid J, Snow GB, Van Dongen GAMS (1993) Labeling of monoclonal antibodies with186Re using the MAG3 chelate for radioimmunotherapy of cancer: a technical protocol. J Nucl Med 34:1953
    PubMed Google Scholar
  40. Wanebo HJ, Blackinton D, Kouttab Mehta S (1993) Contribution of serum inhibitory factors and immune cellular defects to the depressed cell-mediated immunity in patients in patients with head and neck cancer. Am J Surg 166:389
    PubMed Google Scholar
  41. Wessels BW, Harisiadis L, Carabell SC (1989) Dosimetry and radiobiological efficacy of clincial radioimmunotherapy. J Nucl Med 30:827
    Google Scholar
  42. Woodcock D, Crowther PJ, Doherty J, DeCruz E, Noyer-Weidner M, Smith SS, Michal MZ, Graham MW (1989) Quantitative evaluation of_Escherichia coli_ host strains for tolerance to cytosine methylation in plasmid and phage recombinants. Nucl Acids Res 17:3469
    PubMed Google Scholar

Download references