Efficient and fast targeted production of murine models based on ENU mutagenesis (original) (raw)
References
Auerbach W, Dunmore JH, Fairchild-Huntress V, Fang O, Auerbach AB, et al. (2000) Establishment and chimera analysis of 129/SvEv- and C57BL/6-derived mouse embryonic stem cell lines. Biotechniques 29(5): 1024–1032 PubMed Google Scholar
Beier DR, (2000) Sequence-based analysis of mutagenized mice. Mamm Genome 11(7): 594–597 ArticlePubMed Google Scholar
Coghill EL, Hugjll A, Parkinson N, Davidson C, Glenister P, et al. (2002) A gene-driven approach to the identification of ENU mutants in the mouse. Nat Genet 30(3): 255–256 ArticlePubMed Google Scholar
Favor J (1994) Specific-locus mutation test in germ cells of the mouse: an assessment of the screening procedures and the mutational events detected. In Male-Mediated Developmental Toxicity Mattison DR, Olshan AF, eds. (New York: Plenum Press), pp 23–36 Google Scholar
Fitch KR, McGowan KA, van Raamsdonk CD, Fuchs H, Lee D, et al. (2003) Genetics of dark skin in mice. Genes Dev 17(2): 214–228 ArticlePubMed Google Scholar
Girald–Rosa W, Vleugels RA, Musiek AC, Sligh JE (2005) High-throughput mitochondrial genome screening method for nonmelanoma skin cancer using multiplexed temperature gradient capillary electrophoresis. Clin Chem 51: 305–311 ArticlePubMed Google Scholar
Hafezparast M, Klocke R, Ruhrberg C, Marquardt A, Ahmad–Annuar A, et al. (2003) Mutations in dynein link motor neuron degeneration to defects in retrograde transport. Science 300(5620): 808–812 ArticlePubMed Google Scholar
Hansen J, Floss T, Van Sloun P, Fuchtbauer EM, Vauti F, et al. (2003) A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome. Proc Natl Acad Sci U S A 100(17): 9918–9922 ArticlePubMed Google Scholar
Harada A, Takei Y, Kanai Y, Tanaka Y, Nonaka S, et al. (1998) Golgi vesiculation and lysosome dispersion in cells lacking cytoplasmic dynein. J Cell Biol 141(1): 51–59 ArticlePubMed Google Scholar
Hitotsumachi S, Carpenter DA, Russell WL (1985) Dose-repetition increases the mutagenic effectiveness of _N_-ethyl-_N_-nitrosourea in mouse spermatogonia. Proc Natl Acad Sci U S A 82(19): 6619–6621 PubMed Google Scholar
Hrabe de Angelis MH, Flaswinkel H, Fuchs H, Rathkolb B, Soewarto D, et al. (2000) Genome-wide, large-scale production of mutant mice by ENU mutagenesis. Nat Genet 25(4): 444–447 ArticlePubMed Google Scholar
Justice MJ, Carpenter DA, Favor J, Neuhauser-Klaus A, Hrabe de Angelis M, et al. (2000) Effects of ENU dosage on mouse strains. Mamm Genome 11(7): 484–488 ArticlePubMed Google Scholar
Ledermann B (2000) Embryonic stem cells and gene targeting. Exp Physiol 85(6): 603–613 ArticlePubMed Google Scholar
Ledermann B, Burki K (1991) Establishment of a germ-line competent C57BL/6 embryonic stem cell line. Exp Cell Res 197(2): 254–258 ArticlePubMed Google Scholar
Li Q, Liu Z, Monroe H, Culiat CT (2002) Integrated platform for detection of DNA sequence variants using capillary array electrophoresis. Electrophoresis 23(10): 1499–1511 ArticlePubMed Google Scholar
Marschall S, Hrabe de Angelis M (2003) In vitro fertilization/cryopreservation. Methods Mol Biol 209: 35–50 PubMed Google Scholar
Marschall S, Huffstadt U, Balling R, Hrabe de Angelis M (1999) Reliable recovery of inbred mouse lines using cryopreserved spermatozoa. Mamm Genome 10(8): 773–776 ArticlePubMed Google Scholar
Murphy K, Hafez M, Philips J, Yarnell K, Gutshall K, et al. (2003) Evaluation of temperature gradient capillary electrophoresis for detection of the factor v leiden mutation: coincident identification of a novel polymorphism in factor v. Mol Diagn 7(1): 35–40 PubMed Google Scholar
Nadeau JH, Balling R, Barsh G, Beier D, Brown SD, et al. (2001) Sequence interpretation. Functional annotation of mouse genome sequences. Science 291(5507): 1251–1255 ArticlePubMed Google Scholar
Nolan PM, Peters J, Strivens M, Rogers D, Hagan J, et al. (2000) A systematic, genome-wide, phenotype-driven mutagenesis programme for gene function studies in the mouse. Nat Genet 25(4): 440–443 ArticlePubMed Google Scholar
Noveroske JK, Weber JS, Justice MJ (2000) The mutagenic action of _N_-ethyl-_N_-nitrosourea in the mouse. Mamm Genome 11(7): 478–483 ArticlePubMed Google Scholar
Patrucco E, Notte A, Barberis L, Selvetella G, Maffei A, et al. (2004) PI3Kgamma modulates the cardiac response to chronic pressure overload by distinct kinase-dependent and -independent effects. Cell 118(3): 375–387 ArticlePubMed Google Scholar
Quwailid MM, Hugil A, Dear N, Vizor L, Wells S, et al. (2004) A gene-driven ENU-based approach to generating an allelic series in any gene. Mamm Genome 15(8): 585–591 ArticlePubMed Google Scholar
Russ A, Stumm G, Augustin M, Sedlmeir R, Wattler S, et al. (2002) Random mutagenesis in the mouse as a tool in drug discovery. Drug Discov Today 7(23): 1175–1183 ArticlePubMed Google Scholar
Russell WL, Kelly EM, Hunsicker PR, Bangham JW, Maddux SC, et al. (1979) Specific-locus test shows ethylnitrosourea to be the most potent mutagen in the mouse. Proc Natl Acad Sci U S A 76(11): 5818–5819 PubMed Google Scholar
Russell WL, Hunsicker PR, et al. (1982) Effect of dose fractionation on the ethylnitrosourea induction of specific-locus mutations in mouse spermatogonia. Proc Natl Acad Sci U S A 79(11): 3592–3593 PubMed Google Scholar
Schoonjans L, Kreemers V, Danloy S, Moreadith RW, Laroche Y, et al. (2003) Improved generation of germline-competent embryonic stem cell lines from inbred mouse strains. Stem Cells 21(1): 90–97 ArticlePubMed Google Scholar
Silver L (1995)The mouse genome. In Mouse Genetics: Concepts and Applications, Silver L, ed. (City: Oxford University Press) pp 76-133 Google Scholar
Skarnes WC, von Melchner H, Wurst W, Hicks G, Nord AS, et al. (2004) A public gene trap resource for mouse functional genomics. Nat Genet 36(6): 543–544 ArticlePubMed Google Scholar
Threadgill DW, Dlugosz AA, Hansen LA, Tennenbaum T, Lichti U, et al. (1995)/Targeted disruption of mouse EGF receptor: effect of genetic background on mutant phenotype. Science 269(5221): 230–234 PubMed Google Scholar
Threadgill DW, Yee D, Matin A, Nadeau JH, Magnusom T (1997) Genealogy of the 129 inbred strains: 129/SvJ is a contaminated inbred strain. Mamm Genome 8(6): 390–393 ArticlePubMed Google Scholar
Till BJ, Colbert T, Tompa R, Enns LC, Codomo CA, et al. (2003) High-throughput TILLING forunctional genomics. Methods Mol Biol 236: 205–220 Google Scholar
Vanhaesebroeck B, Rohn JL, Waterfield MD (2004) Gene targeting: attention to detail. Cell 118(3): 274–276 ArticlePubMed Google Scholar
Weber JS, Salinger A, Justice MJ (2000) Optimal _N_-ethyl-_N_-nitrosourea (ENU) doses for inbred mouse strains. Genesis 26(4): 230–233 ArticlePubMed Google Scholar
Wichmann B, Hill D (1987) Building a random-number generator. BYTE 12(3), 127–128 Google Scholar
Wiles MV, Vauti F, Otte J, Fuchtbauer EM, Ruiz P, et al. (2000) Establishment of a gene-trap sequence tag library to generate mutant mice from embryonic stem cells. Nat Genet 24(1): 13–14 ArticlePubMed Google Scholar
Zambrowicz BP, Friedrich GA, Buxton EC, Lilleberg SC, Person C, et al. (1998) Disruption and sequence identification of 2,000 genes in mouse embryonic stem cells. Nature 392 (6676), 608–611 ArticlePubMed Google Scholar