Lactobacillus fermentum, a probiotic capable to release glutathione, prevents colonic inflammation in the TNBS model of rat colitis (original) (raw)
Fiocchi C (1998) Inflammatory bowel disease: aetiology and pathogenesis. Gastroenterology 115:182–205 ArticlePubMedCAS Google Scholar
Shanahan F (2000) Probiotics and inflammatory bowel disease: is there a scientific rationale? Inflamm Bowel Dis 6:107–115 ArticlePubMedCAS Google Scholar
Chung PY, Peppercorn MA (1999) Antibiotics in inflammatory bowel disease. Drugs Today 35:89–103 CASPubMed Google Scholar
Taurog JD, Richardson JA, Croft JT, Simmons WA, Zhou M, Fernandez-Sueiro JL, Balish E, Hammer RE (1994) The germ-free state prevents development of gut and joint inflammatory disease in HLA-B27 transgenic rats. J Exp Med 180:2359–2364 ArticlePubMedCAS Google Scholar
Venturi A, Gionchetti P, Rizzello F, Johansson R, Zucconi E, Brigidi P, Matteuzzi D, Campieri M (1999) Impact on the composition of the faecal flora by a new probiotic preparation: preliminary data on maintenance treatment of patients with ulcerative colitis. Aliment Pharmacol Ther 13:1103–1108 ArticlePubMedCAS Google Scholar
Rembacken BJ, Snelling AM, Hawkey PM, Chalmers DM, Axon AT (1999) Non-pathogenic Escherichia coli versus mesalazine for the treatment of ulcerative colitis: a randomised trial. Lancet 354:635–639 ArticlePubMedCAS Google Scholar
Gionchetti P, Rizzello F, Helwig U, Venturi A, Lammers KM, Brigidi P, Vitali B, Poggioli G, Miglioli M, Campieri M (2003) Prophylaxis of pouchitis onset with probiotic therapy: a double-blind, placebo-controlled trial. Gastroenterology 124:1202–1209 ArticlePubMed Google Scholar
Gionchetti P, Rizzello F, Venturi A, Brigidi P, Matteuzzi D, Bazzocchi G, Poggioli G, Miglioli M, Campieri M (2000) Oral bacteriotherapy as maintenance treatment in patients with chronic pouchitis: a double-blind, placebo-controlled trial. Gastroenterology 119:305–309 ArticlePubMedCAS Google Scholar
Tannock GW, Munro K, Harmsen HJ, Welling GW, Smart J, Gopal PK (2000) Analysis of the fecal microflora of human subjects consuming a probiotic product containing Lactobacillus rhamnosus DR20. Appl Environ Microbiol 66:2578–2588 ArticlePubMedCAS Google Scholar
Ulisse S, Gionchetti P, D’Alo S, Russo FP, Pesce I, Ricci G, Rizzello F, Helwig U et al (2001) Expression of cytokines, inducible nitric oxide synthase, and matrix metalloproteinases in pouchitis: effects of probiotic treatment. Am J Gastroenterol 96:2691–2699 ArticlePubMedCAS Google Scholar
Schultz M, Linde HJ, Lehn N, Zimmermann K, Grossmann J, Falk W, Scholmerich J (2003) Immunomodulatory consequences of oral administration of Lactobacillus rhamnosus strain GG in healthy volunteers. J Dairy Res 70:165–173 ArticlePubMedCAS Google Scholar
Madsen K, Cornish A, Soper P, McKaigney C, Jijon H, Yachimec C, Doyle J, Jewell L, De Simone C (2001) Probiotic bacteria enhance murine and human intestinal epithelial barrier function. Gastroenterology 121:580–591 ArticlePubMedCAS Google Scholar
Otte JM, Podolsky DK (2004) Functional modulation of enterocytes by gram-positive and gram-negative microorganisms. Am J Physiol 286:G613–G626 CAS Google Scholar
Steidler L, Hans W, Schotte L, Neirynck S, Obermeier F, Falk W, Fiers W, Remaut E (2000) Treatment of murine colitis by Lactococcus lactis secreting interleukin-10. Science 289:1352–1355 ArticlePubMedCAS Google Scholar
Vandenbroucke K, Hans W, Van Huysse J, Neirynck S, Demetter P, Remaut E, Rottiers P, Steidler L (2004) Active delivery of trefoil factors by genetically modified Lactococcus lactis prevents and heals acute colitis in mice. Gastroenterology 127:502–513 ArticlePubMedCAS Google Scholar
Lamine F, Fioramonti J, Bueno L, Nepveu F, Cauquil E, Lobysheva I, Eutamene H, Theodorou V (2004) Nitric oxide released by Lactobacillus farciminis improves TNBS-induced colitis in rats. Scand J Gastroenterol 39:37–45 ArticlePubMedCAS Google Scholar
Pavlick KP, Laroux FS, Fuseler J, Wolf RE, Gray L, Hoffman J, Grisham MB (2002) Role of reactive metabolites of oxygen and nitrogen in inflammatory bowel disease. Free Radic Biol Med 33:311–322 ArticlePubMedCAS Google Scholar
Buffinton GD, Doe WF (1995) Depleted mucosal antioxidant defences in inflammatory bowel disease. Free Radic Biol Med 19:911–918 ArticlePubMedCAS Google Scholar
Galvez J, Coelho G, Crespo ME, Cruz T, Rodriguez-Cabezas ME, Concha A, Gonzalez M, Zarzuelo A (2001) Intestinal anti-inflammatory activity of morin on chronic experimental colitis in the rat. Aliment Pharmacol Ther 15:2027–2039 ArticlePubMedCAS Google Scholar
Camuesco D, Comalada M, Rodriguez-Cabezas ME, Nieto A, Lorente MD, Concha A, Zarzuelo A, Galvez J (2004) The intestinal anti-inflammatory effect of quercitrin is associated with an inhibition in iNOS expression. Br J Pharmacol, DOI 10.1038/sj.bjp.0705941
Gonzalez R, Sanchez de Medina F, Galvez J, Rodriguez-Cabezas ME, Duarte J, Zarzuelo A (2001) Dietary vitamin E supplementation protects the rat large intestine from experimental inflammation. Int J Vitam Nutr Res 71:243–250 ArticlePubMedCAS Google Scholar
Travis SPL, Jewel DP (1994) Salicylates for ulcerative colitis—their mode of action. Pharmacol Ther 63:135–161 ArticlePubMedCAS Google Scholar
Rachmilewitz D, Karmeli F, Okon E (1995) Sulfhydryl blocker-induced rat colonic inflammation is ameliorated by inhibition of nitric oxide synthase. Gastroenterology 109:98–106 ArticlePubMedCAS Google Scholar
Loguercio C, D’Argenio G, Delle Cave M, Cosenza V, Della Valle N, Mazzacca G, Del Vecchio Blanco C (2003) Glutathione supplementation improves oxidative damage in experimental colitis. Dig Liver Dis 35:635–641 ArticlePubMedCAS Google Scholar
Ardite E, Sans M, Panes J, Romero FJ, Pique JM, Fernandez-Checa JC (2000) Replenishment of glutathione levels improves mucosal function in experimental colitis. Lab Invest 80:735–744 PubMedCAS Google Scholar
Jurjus AR, Khoury NN, Reimund JM (2004) Animal models of inflammatory bowel disease. J Pharmacol Toxicol Methods 50:81–92 ArticlePubMedCAS Google Scholar
Martin R, Langa S, Reviriego C, Jiminez E, Marin ML, Xaus J, Fernandez L, Rodriguez JM (2003) Human milk is a source of lactic acid bacteria for the infant gut. J Pediatr 143:754–758 ArticlePubMedCAS Google Scholar
Morris GP, Beck PL, Herridge W, Depew W, Szewczuk MR, Wallace JL (1989) Hapten induced model of chronic inflammation and ulceration in rat colon. Gastroenterology 96:795–803 PubMedCAS Google Scholar
Bell CJ, Gall DG, Wallace JL (1995) Disruption of colonic electrolyte transport in experimental colitis. Am J Physiol 268:G622–G630 PubMedCAS Google Scholar
Camuesco D, Peran L, Comalada M, Nieto A, Di Stasi LC, Rodriguez-Cabezas ME, Concha A, Zarzuelo A, Galvez J (2005) Preventative effects of lactulose in the trinitrobenzenesulphonic acid model of rat colitis. Inflamm Bowel Dis 11:265–271 ArticlePubMed Google Scholar
Krawisz JE, Sharon P, Stenson WF (1984) Quantitative assay for acute intestinal inflammation based on myeloperoxidase activity. Assessment of inflammation in rat and hamster models. Gastroenterology 87:1344–1350 PubMedCAS Google Scholar
Anderson ME (1985) Determination of glutathione and glutathione disulfide in biological samples. Methods Enzymol 113:548–555 ArticlePubMedCAS Google Scholar
Newton GL, Arnold K, Price MS, Sherrill C, Delcardayre SB, Aharanowitz Y, Cohen G, Davies J et al (1996) Distribution of thiols in microorganisms: mycothiol is a mayor thiol in most Actinomycetes. J Bacteriol 178:1990–1995 PubMedCAS Google Scholar
Fahey RC, Brown WC, Adams WB, Worsham MB (1978) Occurrence of glutathione in bacteria. J Bacteriol 133:1126–1129 PubMedCAS Google Scholar
Galvez J, Garrido M, Rodriguez-Cabezas ME, Ramis I, Sanchez de Medina F, Merlos M, Zarzuelo A (2003) The intestinal anti-inflammatory activity of UR-12746S on reactivated experimental colitis is mediated through downregulation of cytokine production. Inflamm Bowel Dis 9:363–371 ArticlePubMed Google Scholar
Rodriguez-Cabezas ME, Galvez J, Lorente MD, Concha A, Camuesco D, Azzouz S, Osuna A, Redondo L, Zarzuelo A (2002) Dietary fiber down-regulates colonic tumor necrosis factor alpha and nitric oxide production in trinitrobenzenesulfonic acid-induced colitic rats. J Nutr 132:3263–3271 PubMedCAS Google Scholar
Miralles-Barrachina O, Savoye G, Belmonte-Zalar L, Hochain P, Ducrotte P, Hecketsweiler B, Lerebours E, Dechelotte P (1999) Low levels of glutathione in endoscopic biopsies of patients with Crohn’s colitis: the role of malnutrition. Clin Nutr 18:313–317 ArticlePubMedCAS Google Scholar
Schultz M, Sartor RB (2000) Probiotics and inflammatory bowel diseases. Am J Gastroenterol 95:S19–S21 Article Google Scholar
Veljaca M, Lesch CA, Pllana R, Sanchez B, Chan K, Guglietta A (1995) BPC-15 reduces trinitrobenzene sulfonic-induced colonic damage in rats. J Pharmacol Exp Ther 272:417–422 PubMedCAS Google Scholar
Ajuebor MN, Zagorski J, Kunkel SL, Strieter RM, Hogaboam CM (2004) Contrasting roles for CXCR2 during experimental colitis. Exp Mol Pathol 76:1–8 ArticlePubMedCAS Google Scholar
Grisham MB, Olkmer C, Tso P, Yamada T (1991) Metabolism of trinitrobenzene sulfonic acid by rat colon produces reactive oxygen species. Gastroenterology 101:540–547 PubMedCAS Google Scholar
Wu G, Fang YZ, Yang S, Lupton JR, Turner ND (2004) Glutathione metabolism and its implications for health. J Nutr 134:489–492 PubMedCAS Google Scholar
Guo X, Wang WP, Ko JK, Cho CH (1999) Involvement of neutrophils and free radicals in the potentiating effects of passive cigarette smoking on inflammatory bowel disease in rats. Gastroenterology 117:884–892 ArticlePubMedCAS Google Scholar
Rachmilewitz D, Karmeli F, Okon E, Bursztyn M (1995) Experimental colitis is ameliorated by inhibition of nitric oxide synthase activity. Gut 37:247–255 PubMedCAS Google Scholar
Hogaboam CM, Jacobson K, Collins SM Blennerhassett MG (1995) The selective beneficial effects of nitric oxide inhibition in experimental colitis. Am J Physiol 268:G673–G684 PubMedCAS Google Scholar
Kimura H, Miura S, Shigematsu T, Ohkubo N, Tsuzuki Y, Kurose I, Higuchi H, Akiba Y et al (1997) Increased nitric oxide production and inducible nitric oxide synthase activity in colonic mucosa of patients with active ulcerative colitis and Crohn’s disease. Dig Dis Sci 42:1047–1054 ArticlePubMedCAS Google Scholar
Ikeda I, Kasajima T, Ishiyama S, Shimojo T, Takeo Y, Nishikawa T, Kameoka S, Hiroe M, Mitsunaga A (1997) Distribution of inducible nitric oxide synthase in ulcerative colitis. Am J Gastroenterol 92:1339–1341 PubMedCAS Google Scholar
McCafferty DM, Miampamba M, Sihota E, Sharkey KA, Kubes P (1999) Role of inducible nitric oxide synthase in trinitrobenzene sulphonic acid induced colitis in mice. Gut 45:864–873 ArticlePubMedCAS Google Scholar
Van Deventer SJH (1997) Tumor necrosis factor and Crohn’s disease. Gut 40:443–448 PubMed Google Scholar
Rutgeerts P, Van Assche G, Vermeire S (2004) Optimizing anti-TNF treatment in inflammatory bowel disease. Gastroenterology 126:1593–1610 ArticlePubMedCAS Google Scholar
Borruel N, Carol M, Casellas F, Antolin M, de Lara F, Espin E, Naval J, Guarner F, Malagelada JR (2002) Increased mucosal tumour necrosis factor alpha production in Crohn’s disease can be downregulated ex vivo by probiotic bacteria. Gut 51:659–664 ArticlePubMedCAS Google Scholar
Schottelius AJ, Baldwin AS Jr (1999) A role for transcription factor NF-kappa B in intestinal inflammation. Int J Colorectal Dis 14:18–28 ArticlePubMedCAS Google Scholar
Segain JP, Raingeard de la Bletiere D, Bourreille A, Leray V, Gervois N, Rosales C, Ferrier L, Bonnet C et al (2000) Butyrate inhibits inflammatory responses through NFκB inhibition: implications for Crohn’s disease. Gut 47:397–403 ArticlePubMedCAS Google Scholar
Inan MS, Rasoulpour RJ, Yin L, Hubbard AK, Rosenberg DW, Giardina C (2000) The luminal short-chain fatty acid butyrate modulates NF-κB activity in a human colonic epithelial cell line. Gastroenterology 118:724–734 ArticlePubMedCAS Google Scholar
Rogler G, Brand K, Vogl D, Page S, Hofmeister R, Andus T, Knuechel R, Baeuerle PA et al (1998) Nuclear factor kappaB is activated in macrophages and epithelial cells of inflamed intestinal mucosa. Gastroenterology 115:357–369 ArticlePubMedCAS Google Scholar
Garcia-Lafuente A, Antolin M, Guarner F, Crespo E, Salas A, Forcada P, Laguarda M, Gavalda J et al (1997) Incrimination of anaerobic bacteria in the induction of experimental colitis. Am J Physiol 272:G10–G15 PubMedCAS Google Scholar