Ultrastructural localization of TDP-43 in filamentous neuronal inclusions in various neurodegenerative diseases (original) (raw)
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References
- Amador-Ortiz C, Lin WL, Ahmed Z, Personett D, Davies P, Duara R et al (2007) TDP-43 immunoreactivity in hippocampal sclerosis and Alzheimer’s disease. Ann Neurol 61:435–445. doi:10.1002/ana.21154
Article PubMed CAS Google Scholar - Arai T, Hasegawa M, Akiyama H, Ikeda K, Nonaka T, Mori H et al (2006) TDP-43 is a component of ubiquitin-positive tau-negative inclusions in frontotemporal lobar degeneration and amyotrophic lateral sclerosis. Biochem Biophys Res Commun 351:602–611. doi:10.1016/j.bbrc.2006.10.093
Article PubMed CAS Google Scholar - Cairns NJ, Newmann M, Bigio EH, Holm IE, Troost D, Hatanpaa KJ, Foong C, White ICL, Schneider JA, Kretzschmar HA, Carter D, Taylor-Reinwald L, Paulsmeyer K, Strider J, Gitcho M, Goate AM, Morris JC, Mishra M, Kwong LK, Stieber A, Xu Y, Forman MS, Trojanowski JQ, Lee VM-Y, Mackenzie IRA (2007) TDP-43 in familial and sporadic frontotemporal lobar degeneration with ubiquitin inclusions. Am J Pathol 171:227–240. doi:10.2353/ajpath.2007.070182
Article PubMed CAS Google Scholar - Dickson DW, Wertkin A, Mattiace LA, Fier E, Kress Y, Davies P et al (1990) Ubiquitin immunoelectron microscopy of dystrophic neurites in cerebellar senile plaques of Alzheimer’s disease. Acta Neuropathol 79:486–493. doi:10.1007/BF00296107
Article PubMed CAS Google Scholar - Freeman SH, Spires-Jones T, Hyman BT, Growdon JH, Frosch MP (2008) TDP-DNA binding protein 43 in Pick Disease. J Neuropathol Exp Neurol 67:62–67. doi:10.1097/nen.0b013e3181609361
Article PubMed CAS Google Scholar - Geser F, Winton MJ, Kwong LK, Xu Y, Xie SX, Igaz LM et al (2008) Pathological TDP-43 in parkinsonism-dementia complex and amyotrophic lateral sclerosis of Guam. Acta Neuropathol 115:133–145. doi:10.1007/s00401-007-0257-y
Article PubMed CAS Google Scholar - Gilman CP, Mattson MP (2002) Do apoptotic mechanisms regulate synaptic plasticity and growth-cone motility? Neuromolecular Med 2:197–214. doi:10.1385/NMM:2:2:197
Article PubMed CAS Google Scholar - Gwinn-Hardy K, Mehta ND, Farrer M, Maraganore D, Muenter M, Yen SH et al (2000) Distinctive neuropathology revealed by alpha-synuclein antibodies in hereditary Parkinsonism and dementia linked to chromosome 4p. Acta Neuropathol 99:663–672. doi:10.1007/s004010051177
Article PubMed CAS Google Scholar - Hasegawa M, Arai T, Akiyama H, Nonaka T, Mori H, Hashimoto T et al (2007) TDP-43 is deposited in the Guam parkinsonism-dementia complex brains. Brain 130:1386–1394. doi:10.1093/brain/awm065
Article PubMed Google Scholar - Hasegawa M, Arai T, Nonaka T, Kametani F, Yoshida M, Hashizume Y, et al. (2008) Phosphorylated TDP-43 in frontotemporal lobar degeneration and amyotrophic lateral sclerosis. Ann Neurol, Epub ahead of print. doi:10.1002/ana.21425
- Higashi S, Iseki E, Yamamoto R, Minegishi M, Hino H, Fujisawa K et al (2007) Concurrence of TDP-43, tau and α-synuclein pathology in brains of Alzheimer’s disease and dementia with Lewy bodies. Brain Res 1184:284–294. doi:10.1016/j.brainres.2007.09.048
Article PubMed CAS Google Scholar - Iseki E, Li F, Odawara T, Hino H, Suzuki K, Kosaka K et al (1998) Ubiquitin-immunohistochemical investigation of atypical Pick’s disease without Pick bodies. J Neurol Sci 159:194–201. doi:10.1016/S0022-510X(98)00168-3
Article PubMed Google Scholar - Ishizawa T, Mattila P, Davies P, Wang D, Dickson DW (2003) Colocalization of tau and alpha-synuclein epitopes in Lewy bodies. J Neuropathol Exp Neurol 62:389–397
PubMed CAS Google Scholar - Kinoshita A, Tomimoto H, Suenaga T, Akiguchi I, Kimura J (1997) Ubiquitin-related cytoskeletal abnormality in frontotemporal dementia: immunohistochemical and immunoelectron microscope studies. Acta Neuropathol 94:67–72. doi:10.1007/s004010050673
Article PubMed CAS Google Scholar - Kuzuhara S (2007) TDP–43 accumulation in ALS/parkinsonism-dementia complex (ALS/PDC) of the Kii peninsula of Japan. Neuropathology 27:61 abstr
Google Scholar - Lin WL, Lewis J, Yen SH, Hutton M, Dickson DW (2003) Filamentous tau in oligodendrocytes and astrocytes of transgenic mice expressing the human tau isoform with the P301L mutation. Am J Pathol 162:213–218
PubMed CAS Google Scholar - Nakashima-Yasuda H, Uryu K, Robinson J, Xie SX, Hurtig HI, Duda JE et al (2007) Co-morbidity of TDP-43 proteinopathy in Lewy body related disease. Acta Neuropathol 114:221–229. doi:10.1007/s00401-007-0261-2
Article PubMed CAS Google Scholar - Neumann M, Sampathu DM, Kwong LK, Truax AC, Micsenyi MC, Chou TT et al (2006) Ubiquitinated TDP-43 in frontotemporal lobar degeneration and amyotrophic lateral sclerosis. Science 314:130–133. doi:10.1126/science.1134108
Article PubMed CAS Google Scholar - Okamoto K, Murakami N, Kusaka H, Yoshida M, Hashizume Y, Nakazato Y et al (1992) Ubiquitin-positive intraneuronal inclusions in the extramotor cortices of presenile dementia patients with motor neuron disease. J Neurol 239:426–430. doi:10.1007/BF00856806
Article PubMed CAS Google Scholar - Polymeropoulos MH, Lavedan C, Leroy E, Ide SE, Dehejia A, Dutra A et al (1997) Mutation in the alpha-synuclein gene identified in families with Parkinson’s disease. Science 276:2045–2047. doi:10.1126/science.276.5321.2045
Article PubMed CAS Google Scholar - Wang I-F, Wu L-S, Chang H-Y, Shen C-K (2008) TDP-43, the signature protein of FTLD-U is a neuronal activity-responsive factor. J Neurochem 105:797–806. doi:10.1111/j.1471-4159.2007.05190.x
Article PubMed CAS Google Scholar - Zhang Y-J, Xu Y-F, Dickey CA, Buratti E, Baralle F, Bailey R et al (2007) Progranulin mediates caspase-dependent cleavage of TAR DNA binding protein-43. J Neurosci 27:10530–10534. doi:10.1523/JNEUROSCI.3421-07.2007
Article PubMed CAS Google Scholar