Variable number tandem repeat dopamine transporter gene polymorphism and Parkinson’s disease: no association found (original) (raw)

Abstract.

We studied a variable number of tandem repeat polymorphisms in the dopamine transporter gene in search of an association with Parkinson’s disease in a French population. Five alleles were detected, consisting of 7, 8, 9, 10 and 11 copies of the 40-base pair repeat sequence, of which the 10-copy allele was the most common. There was no significant difference between the patients and the control subjects in the distribution frequencies of the alleles or genotypes, or in ages at onset in patients between the main allelic classes.

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Authors and Affiliations

1. Laboratoire de Neurogénétique Moléculaire (Service de Neurologie) Hôpital Maison Blanche 45 rue Cognacq-Jay F-51092 Reims, France, , , , , , FR
   G. Mercier, J. C. Turpin & G. Lucotte

Authors

1. G. Mercier
2. J. C. Turpin
3. G. Lucotte

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Received: 12 February 1998 Received in revised form: 4 May 1998 Accepted: 22 May 1998

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Mercier, G., Turpin, J. & Lucotte, G. Variable number tandem repeat dopamine transporter gene polymorphism and Parkinson’s disease: no association found.J Neurol 246, 45–47 (1999). https://doi.org/10.1007/s004150050304

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• Issue date: January 1999
• DOI: https://doi.org/10.1007/s004150050304