Organising activities of engrailed, hedgehog, wingless and decapentaplegic in the genital discs of Drosophila melanogaster (original) (raw)

Abstract

The genes engrailed (en), hedgehog (hh), wingless (wg) and decapentaplegic (dpp) have been shown to play vital organising roles in the development and differentiation of thoracic imaginal discs. We have analysed the roles of these genes in organising the development and differentiation of the genital discs, which are bilaterally symmetrical and possess different primordia, namely, the male and female genital primordia and an anal primordium. Our results suggest that the organising activity of en in genital discs programs the normal development and differentiation of the genital disc by regulating the expression of hh. Hh in turn induces wg and dpp, the genes whose products act as secondary signalling molecules. Moreover, the complementary patterns of wg and dpp expression are essential for the bilateral symmetry and are maintained by mutual repression.

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Authors and Affiliations

  1. Cytogenetics Laboratory, Department of Zoology, Banaras Hindu University, Varanasi 221 005, India, , , , , , IN
    B. S. Emerald & J. K. Roy

Authors

  1. B. S. Emerald
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  2. J. K. Roy
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Received: 20 April 1998 / Accepted 24 June 1998

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Emerald, B., Roy, J. Organising activities of engrailed, hedgehog, wingless and decapentaplegic in the genital discs of Drosophila melanogaster.Dev Gene Evol 208, 504–516 (1998). https://doi.org/10.1007/s004270050209

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