Tumor cell invasion and survival in head and neck cancer (original) (raw)

References

1. Califano J, van der Riet P, Westra W, Nawroz H, Clayman G, Piantadosi S, Corio R, Lee D, Greenberg B, Koch W, Sidransky D: Genetic progression model for head and neck cancer: Implications for field cancerization. Cancer Res 56: 2488–2492, 1996
   PubMed CAS Google Scholar
2. Califano J, Westra WH, Meininger G, Corio R, Koch WM, Sidransky D: Genetic progression and clonal relationship of recurrent premalignant head and neck lesions. Clin Cancer Res 6: 347–352, 2000
   PubMed CAS Google Scholar
3. Ziober BL, Silverman SS, Jr. Kramer RH: Adhesive mechanisms regulating invasion and metastasis in oral cancer. Crit Rev Oral Biol Med 12: 499–510, 2001
   Article PubMed CAS Google Scholar
4. Ziober BL, Kramer RH: Chapter 6: Adhesion receptors in oral cancer invasion. In: Ensley JF, Gutkind JS (eds) Head and Neck Cancer. Elsevier Science, 2003, pp 65–79
5. Colognato H, Yurchenco PD: Form and function: The laminin family of heterotrimers. Dev Dyn 218: 213–234, 2000
   Article CAS PubMed Google Scholar
6. Nguyen BP, Ryan MC, Gil SG, Carter WG: Deposition of laminin 5 in epidermal wounds regulates integrin signaling and adhesion. Curr Opin Cell Biol 12: 554–562, 2000
   Article CAS PubMed Google Scholar
7. Rousselle P, Lunstrum GP, Keene DR, Burgeson RE: Kalinin: an epithelium-specific basement membrane adhesion molecule that is a component of anchoring filaments. J Cell Biol 114: 567–576, 1991
   Article PubMed CAS Google Scholar
8. Pyke C, Salo S, Ralfkiaer E, Romer J, Dano K, Tryggvason K: Laminin-5 is a marker of invading cancer cells in some human carcinomas and is coexpressed with the receptor for urokinase plasminogen activator in budding cancer cells in colon adenocarcinomas. Cancer Res 55: 4132–4139, 1995
   CAS PubMed Google Scholar
9. Zhang K, Kramer RH: Laminin 5 deposition promotes keratinocyte motility. Exp Cell Res 227: 309–322, 1996
   PubMed CAS Google Scholar
10. Kainulainen T, Autio-Harmainen H, Oikarinen A, Salo S, Tryggvason K, Salo T: Altered distribution and synthesis of laminin-5 (kalinin) in oral lichen planus, epithelial dysplasias and squamous cell carcinomas. Br J Dermatol 136: 331–336, 1997
    Article PubMed CAS Google Scholar
11. Ono Y, Nakanishi Y, Ino Y, Niki T, Yamada T, Yoshimura K, Saikawa M, Nakajima T, Hirohashi S: Clinocopathologic significance of laminin-5 gamma2 chain expression in squamous cell carcinoma of the tongue: Immunohistochemical analysis of 67 lesions. Cancer 85: 2315–2321, 1999
    PubMed CAS Google Scholar
12. Ginos MA, Page GP, Michalowicz BS, Patel KJ, Volker SE, Pambuccian SE, Ondrey FG, Adams GL, Gaffney PM: Identification of a gene expression signature associated with recurrent disease in squamous cell carcinoma of the head and neck. Cancer Res 64: 55–63, 2004
    PubMed CAS Google Scholar
13. Patarroyo M, Tryggvason K, Virtanen I: Laminin isoforms in tumor invasion, angiogenesis and metastasis. Semin Cancer Biol 12: 197–207, 2002
    Article CAS PubMed Google Scholar
14. Patel V, Aldridge K, Ensley JF, Odell E, Boyd A, Jones J, Gutkind JS, Yeudall WA: Laminin-gamma2 overexpression in head-and-neck squamous cell carcinoma. Int J Cancer 99: 583–588, 2002
    PubMed CAS Google Scholar
15. Niki T, Kohno T, Iba S, Moriya Y, Takahashi Y, Saito M, Maeshima A, Yamada T, Matsuno Y, Fukayama M, Yokota J, Hirohashi S: Frequent co-localization of Cox-2 and laminin-5 gamma2 chain at the invasive front of early-stage lung adenocarcinomas. Am J Pathol 160: 1129–1141, 2002
    PubMed CAS Google Scholar
16. Kosmehl H, Berndt A, Strassburger S, Borsi L, Rousselle P, Mandel U, Hyckel P, Zardi L, Katenkamp D: Distribution of laminin and fibronectin isoforms in oral mucosa and oral squamous cell carcinoma. Br J Cancer 81: 1071–1079, 1999
    Article CAS PubMed Google Scholar
17. Aumailley M, El Khal A, Knoss N, Tunggal L: Laminin 5 processing and its integration into the ECM. Matrix Biol 22: 49–54, 2003
    PubMed CAS Google Scholar
18. Goldfinger LE, Stack MS, Jones JC: Processing of laminin-5 and its functional consequences: Role of plasmin and tissue-type plasminogen activator. J Cell Biol 141: 255–265, 1998
    PubMed CAS Google Scholar
19. Goldfinger LE, Hopkinson SB, deHart GW, Collawn S, Couchman JR, Jones JC: The alpha3 laminin subunit, alpha6beta4 and alpha3beta1 integrin coordinately regulate wound healing in cultured epithelial cells and in the skin. J Cell Sci 112(Pt 16): 2615–2629, 1999
    PubMed CAS Google Scholar
20. Shang M, Koshikawa N, Schenk S, Quaranta V: The LG3 module of laminin-5 harbors a binding site for integrin alpha3beta1 that promotes cell adhesion, spreading, and migration. J Biol Chem 276: 33045–33053, 2001
    PubMed CAS Google Scholar
21. Giannelli G, Falk-Marzillier J, Schiraldi O, Stetler-Stevenson WG, Quaranta V: Induction of cell migration by matrix metalloprotease-2 cleavage of laminin-5. Science 277: 225–228, 1997
    Article CAS PubMed Google Scholar
22. Koshikawa N, Giannelli G, Cirulli V, Miyazaki K, Quaranta V: Role of cell surface metalloprotease MT1-MMP in epithelial cell migration over laminin-5. J Cell Biol 148: 615–624, 2000
    Article CAS PubMed Google Scholar
23. Ondruschka C, Buhtz P, Motsch C, Freigang B, Schneider-Stock R, Roessner A, Boltze C: Prognostic value of MMP-2, -9 and TIMP-1,-2 immunoreactive protein at the invasive front in advanced head and neck squamous cell carcinomas. Pathol Res Pract 198: 509–515, 2002
    PubMed Google Scholar
24. Yoshizaki T, Sato H, Maruyama Y, Murono S, Furukawa M, Park CS, Seiki M: Increased expression of membrane type 1-matrix metalloproteinase in head and neck carcinoma. Cancer 79: 139–144, 1997
    PubMed CAS Google Scholar
25. Dumas V, Kanitakis J, Charvat S, Euvrard S, Faure M, Claudy A: Expression of basement membrane antigens and matrix metalloproteinases 2 and 9 in cutaneous basal and squamous cell carcinomas. Anticancer Res 19: 2929–2938, 1999
    PubMed CAS Google Scholar
26. Amano S, Scott IC, Takahara K, Koch M, Champliaud MF, Gerecke DR, Keene DR, Hudson DL, Nishiyama T, Lee S, Greenspan DS, Burgeson RE: Bone morphogenetic protein 1 is an extracellular processing enzyme of the laminin 5 gamma 2 chain. J Biol Chem 275: 22728–22735, 2000
    PubMed CAS Google Scholar
27. Veitch DP, Nokelainen P, McGowan KA, Nguyen TT, Nguyen NE, Stephenson R, Pappano WN, Keene DR, Spong SM, Greenspan DS, Findell PR, Marinkovich MP: Mammalian tolloid metalloproteinase, and not matrix metalloprotease 2 or membrane type 1 metalloprotease, processes laminin-5 in keratinocytes and skin. J Biol Chem 278: 15661–15668, 2003
    PubMed CAS Google Scholar
28. Baker SE, Hopkinson SB, Fitchmun M, Andreason GL, Frasier F, Plopper G, Quaranta V, Jones JC: Laminin-5 and hemidesmosomes: role of the alpha 3 chain subunit in hemidesmosome stability and assembly. J Cell Sci 109(Pt 10): 2509–2520, 1996
    PubMed CAS Google Scholar
29. Mizushima H, Takamura H, Miyagi Y, Kikkawa Y, Yamanaka N, Yasumitsu H, Misugi K, Miyazaki K: Identification of integrin-dependent and -independent cell adhesion domains in COOH-terminal globular region of laminin-5 alpha 3 chain. Cell Growth Differ 8: 979–987, 1997
    PubMed CAS Google Scholar
30. DiPersio CM, Hodivala-Dilke KM, Jaenisch R, Kreidberg JA, Hynes RO: alpha3beta1 Integrin is required for normal development of the epidermal basement membrane. J Cell Biol 137: 729–742, 1997
    PubMed CAS Google Scholar
31. Carter WG, Ryan MC, Gahr PJ: Epiligrin, a new cell adhesion ligand for integrin alpha 3 beta 1 in epithelial basement membranes. Cell 65: 599–610, 1991
    PubMed CAS Google Scholar
32. Gonzales M, Haan K, Baker SE, Fitchmun M, Todorov I, Weitzman S, Jones JC: A cell signal pathway involving laminin-5, alpha3beta1 integrin, and mitogen-activated protein kinase can regulate epithelial cell proliferation. Mol Biol Cell 10: 259–270, 1999
    PubMed CAS Google Scholar
33. Zhang K, Kim JP, Woodley DT, Waleh NS, Chen YQ, Kramer RH: Restricted expression and function of laminin 1-binding integrins in normal and malignant oral mucosal keratinocytes. Cell Adhes. Commun 4: 159–174, 1996
    PubMed CAS Google Scholar
34. Jones J, Sugiyama M, Giancotti F, Speight PM, Watt FM: Transfection of beta 4 integrin subunit into a neoplastic keratinocyte line fails to restore terminal differentiation capacity or influence proliferation. Cell Adhes Commun 4: 307–316, 1996
    PubMed CAS Google Scholar
35. Mercurio AM, Rabinovitz I, Shaw LM: The alpha6beta4 integrin and epithelial cell migration. Curr Opin Cell Biol 13: 541–545, 2001
    PubMed CAS Google Scholar
36. Rabinovitz I, Mercurio AM: The integrin alpha6beta4 functions in carcinoma cell migration on laminin-1 by mediating the formation and stabilization of actin-containing motility structures. J Cell Biol 139: 1873–1884, 1997
    PubMed CAS Google Scholar
37. Lauffenburger DA, Horwitz AF: Cell migration: A physically integrated molecular process. Cell 84: 359–369, 1996
    Article CAS PubMed Google Scholar
38. Ridley AJ, Schwartz MA, Burridge K, Firtel RA, Ginsberg MH, Borisy G, Parsons JT, Horwitz AR: Cell migration: integrating signals from front to back. Science 302: 1704–1709, 2003
    Article CAS PubMed Google Scholar
39. Horwitz R, Webb D: Cell migration. Curr Biol 13: R756–759, 2003
    PubMed CAS Google Scholar
40. Raftopoulou M, Hall A: Cell migration: Rho GTPases lead the way. Dev Biol 265: 23–32, 2004
    PubMed CAS Google Scholar
41. Kawano K, Kantak S, Murai M, Yao C-C, Kramer R: Integrin alpha 3 beta 1 engagement disrupts intercellular adhesion. Exp. Cell Res. 262: 180–196, 2001
    PubMed CAS Google Scholar
42. Zhou H, Kramer RH: Rho small GTPases in cell motility in squamous cell carcinoma Mol Biol Cell 14: 469a, 2003.
    Google Scholar
43. Hordijk PL, ten Klooster JP, van der Kammen RA, Michiels F, Oomen LC, Collard JG: Inhibition of invasion of epithelial cells by Tiam1-Rac signaling. Science 278: 1464–1466, 1997
    PubMed CAS Google Scholar
44. Michiels F, Habets GG, Stam JC, van der Kammen RA, Collard JG: A role for Rac in Tiam1-induced membrane ruffling and invasion. Nature 375: 338–340, 1995
    PubMed CAS Google Scholar
45. Stam JC, Michiels F, van der Kammen RA, Moolenaar WH, Collard JG: Invasion of T-lymphoma cells: Cooperation between Rho family GTPases and lysophospholipid receptor signaling. Embo J 17: 4066–4074, 1998
    Article CAS PubMed Google Scholar
46. Evers EE, van der Kammen RA, ten Klooster JP, Collard JG: Rho-like GTPases in tumor cell invasion. Methods Enzymol 325: 403–415, 2000
    Article PubMed CAS Google Scholar
47. Zondag GC, Evers EE, ten Klooster JP, Janssen L, van der Kammen RA, Collard JG: Oncogenic Ras downregulates Rac activity, which leads to increased Rho activity and epithelial-mesenchymal transition. J Cell Biol 149: 775–782, 2000
    PubMed CAS Google Scholar
48. Abraham MT, Kuriakose MA, Sacks PG, Yee H, Chiriboga L, Bearer EL, Delacure MD: Motility-related proteins as markers for head and neck squamous cell cancer. Laryngoscope 111: 1285–1289, 2001
    PubMed CAS Google Scholar
49. van Golen KL, Wu ZF, Qiao XT, Bao LW, Merajver SD: RhoC GTPase, a novel transforming oncogene for human mammary epithelial cells that partially recapitulates the inflammatory breast cancer phenotype. Cancer Res 60: 5832–5838, 2000
    PubMed CAS Google Scholar
50. Liu A, Du W, Liu JP, Jessell TM, Prendergast GC: RhoB alteration is necessary for apoptotic and antineoplastic responses to farnesyltransferase inhibitors. Mol Cell Biol 20: 6105–6113, 2000
    PubMed CAS Google Scholar
51. Liu AX, Rane N, Liu JP, Prendergast GC: RhoB is dispensable for mouse development, but it modifies susceptibility to tumor formation as well as cell adhesion and growth factor signaling in transformed cells. Mol Cell Biol 21: 6906–6912, 2001
    Google Scholar
52. Mira JP, Benard V, Groffen J, Sanders LC, Knaus UG: Endogenous, hyperactive Rac3 controls proliferation of breast cancer cells by a p21-activated kinase-dependent pathway. Proc Natl Acad Sci USA 97: 185–189, 2000
    PubMed CAS Google Scholar
53. Malliri A, van der Kammen RA, Clark K, van der Valk M, Michiels F, Collard JG: Mice deficient in the Rac activator Tiam1 are resistant to Ras-induced skin tumours. Nature 417: 867–871, 2002
    PubMed CAS Google Scholar
54. Wang DZ, Nur EKMS, Tikoo A, Montague W, Maruta H: The GTPase and Rho GAP domains of p190, a tumor suppressor protein that binds the M(r) 120,000 Ras GAP, independently function as anti-Ras tumor suppressors. Cancer Res 57: 2478–2484, 1997
    PubMed CAS Google Scholar
55. Tikoo A, Czekay S, Viars C, White S, Heath JK, Arden K, Maruta H: p190-A, a human tumor suppressor gene, maps to the chromosomal region 19q13.3 that is reportedly deleted in some gliomas. Gene 257: 23–31, 2000
    Google Scholar
56. Kuroda S, Fukata M, Nakagawa M, Fujii K, Nakamura T, Ookubo T, Izawa I, Nagase T, Nomura N, Tani H, Shoji I, Matsuura Y, Yonehara S, Kaibuchi K: Role of IQGAP1, a target of the small GTPases Cdc42 and Rac1, in regulation of E-cadherin-mediated cell-cell adhesion. Science 281: 832–835, 1998
    PubMed CAS Google Scholar
57. Ho YD, Joyal JL, Li Z, Sacks DB: IQGAP1 integrates Ca2+/calmodulin and Cdc42 signaling. J Biol Chem 274: 464–470, 1999
    PubMed CAS Google Scholar
58. Swart-Mataraza JM, Li Z, Sacks DB: IQGAP1 is a component of Cdc42 signaling to the cytoskeleton. J Biol Chem 277: 24753–24763, 2002
    PubMed CAS Google Scholar
59. Manser E, Lim L: Roles of PAK family kinases. Prog Mol Subcell Biol 22: 115–133, 1999
    PubMed CAS Google Scholar
60. Vadlamudi RK, Adam L, Wang RA, Mandal M, Nguyen D, Sahin A, Chernoff J, Hung MC, Kumar R: Regulatable expression of p21-activated kinase-1 promotes anchorage-independent growth and abnormal organization of mitotic spindles in human epithelial breast cancer cells. J Biol Chem 275: 36238-36244, 2000
    PubMed CAS Google Scholar
61. McMullan R, Lax S, Robertson VH, Radford DJ, Broad S, Watt FM, Rowles A, Croft DR, Olson MF, Hotchin NA: Keratinocyte differentiation is regulated by the Rho and ROCK signaling pathway. Curr Biol 13: 2185–2189, 2003
    PubMed CAS Google Scholar
62. Kamai T, Tsujii T, Arai K, Takagi K, Asami H, Ito Y, Oshima H: Significant association of Rho/ROCK pathway with invasion and metastasis of bladder cancer. Clin Cancer Res 9: 2632–2641, 2003
    PubMed CAS Google Scholar
63. Nakajima M, Hayashi K, Egi Y, Katayama K, Amano Y, Uehata M, Ohtsuki M, Fujii A, Oshita K, Kataoka H, Chiba K, Goto N, Kondo T: Effect of Wf-536, a novel ROCK inhibitor, against metastasis of B16 melanoma. Cancer Chemother Pharmacol 52: 319–324, 2003
    PubMed CAS Google Scholar
64. Nishimura Y, Itoh K, Yoshioka K, Tokuda K, Himeno M: Overexpression of ROCK in human breast cancer cells: Evidence that ROCK activity mediates intracellular membrane traffic of lysosomes. Pathol Oncol Res 9: 83–95, 2003
    Article PubMed CAS Google Scholar
65. Sahai E, Marshall CJ: Differing modes of tumour cell invasion have distinct requirements for Rho/ROCK signalling and extracellular proteolysis. Nat Cell Biol 5: 711–719, 2003
    PubMed CAS Google Scholar
66. Gumbiner BM: Cell adhesion: The molecular basis of tissue architecture and morphogenesis. Cell 84: 345–357, 1996
    PubMed CAS Google Scholar
67. Takeichi M: Cadherin cell adhesion receptors as a morphogenetic regulator. Science 251: 1451–1455, 1991
    PubMed CAS Google Scholar
68. Nelson WJ, Nusse R: Convergence of Wnt, beta-catenin, and cadherin pathways. Science 303: 1483–1487, 2004
    Article CAS PubMed Google Scholar
69. Yap AS, Niessen CM, Gumbiner BM: The juxtamembrane region of the cadherin cytoplasmic tail supports lateral clustering, adhesive strengthening, and interaction with p120ctn. J Cell Biol 141: 779–789, 1998
    Google Scholar
70. Navarro P, Gomez M, Pizarro A, Gamallo C, Quintanilla M, Cano A: A role for the E-cadherin cell-cell adhesion molecule during tumor progression of mouse epidermal carcinogenesis. J Cell Biol 115: 517–533, 1991
    PubMed CAS Google Scholar
71. Andrews NA, Jones AS, Helliwell TR, Kinsella AR: Expression of the E-cadherin-catenin cell adhesion complex in primary squamous cell carcinomas of the head and neck and their nodal metastases. Br J Cancer 75: 1474–1480, 1997
    PubMed CAS Google Scholar
72. Bowie GL, Caslin AW, Roland NJ, Field JK, Jones AS, Kinsella AR: Expression of the cell-cell adhesion molecule E-cadherin in squamous cell carcinoma of the head and neck. Clin Otolaryngol 18: 196–201, 1993
    Article PubMed CAS Google Scholar
73. Lango MN, Shin DM, Grandis JR: Targeting growth factor receptors: integration of novel therapeutics in the management of head and neck cancer. Curr Opin Oncol 13: 168–175, 2001
    PubMed CAS Google Scholar
74. Mattijssen V, Peters HM, Schalkwijk L, Manni JJ, van’t Hof-Grootenboer B, de Mulder PH, Ruiter DJ: E-cadherin expression in head and neck squamous-cell carcinoma is associated with clinical outcome. Int J Cancer 55: 580–585, 1993
    PubMed CAS Google Scholar
75. Wong AS, Gumbiner BM: Adhesion-independent mechanism for suppression of tumor cell invasion by E-cadherin. J Cell Biol 161: 1191–1203, 2003
    PubMed CAS Google Scholar
76. Yamada KM, Geiger B: Molecular interactions in cell adhesion complexes. Curr Opin Cell Biol 9: 76–85, 1997
    PubMed CAS Google Scholar
77. Pollack AL, Barth AI, Altschuler Y, Nelson WJ, Mostov KE: Dynamics of beta-catenin interactions with APC protein regulate epithelial tubulogenesis. J Cell Biol 137: 1651–1662, 1997
    Article CAS PubMed Google Scholar
78. Tao YS, Edwards RA, Tubb B, Wang S, Bryan J, McCrea PD: Beta-Catenin associates with the actin-bundling protein fascin in a noncadherin complex. J Cell Biol 134: 1271–1281, 1996
    Google Scholar
79. Hoschuetzky H, Aberle H, Kemler R: Beta-catenin mediates the interaction of the cadherin-catenin complex with epidermal growth factor receptor. J Cell Biol 127: 1375–1380, 1994
    PubMed CAS Google Scholar
80. Shibata T, Ochiai A, Kanai Y, Akimoto S, Gotoh M, Yasui N, Machinami R, Hirohashi S: Dominant-negative inhibition of the association between beta-catenin and c-34B-2 by N-terminally deleted beta-catenin suppresses the invasion and metastasis of cancer cells. Oncogene 13: 883–889, 1996
    PubMed CAS Google Scholar
81. Pece S, Chiariello M, Murga C, Gutkind J: Activation of the protein kinase Akt/PKB by the formation of E-cadherin-mediated cell-cell junctions. Evidence for the association of phosphatidylinositol 3-kinase with the E-cadherin adhesion complex. J Biol Chem 274: 19347–19351, 1999
    PubMed CAS Google Scholar
82. Pece S, Gutkind JS: Signaling from E-cadherins to the MAPK pathway by the recruitment and activation of epidermal growth factor receptors upon cell-cell contact formation. J Biol Chem 275: 41227–41233, 2000
    PubMed CAS Google Scholar
83. Xu Y, Guo DF, Davidson M, Inagami T, Carpenter G: Interaction of the adaptor protein Shc and the adhesion molecule cadherin. J Biol Chem 272: 13463–13466, 1997
    PubMed CAS Google Scholar
84. Ilic D, Damsky CH: Integrin signaling-it’s where the action is. Curr Opin Cell Biol (in press): 2002
85. Juliano RL: Signal transduction by cell adhesion receptors and the cytoskeleton: Functions of integrins, cadherins, selectins, and immunoglobulin-superfamily members. Annu Rev Pharmacol Toxicol 42: 283–323, 2002
    PubMed CAS Google Scholar
86. St Croix B, Florenes VA, Rak JW, Flanagan M, Bhattacharya N, Slingerland JM, Kerbel RS: Impact of the cyclin-dependent kinase inhibitor p27Kip1 on resistance of tumor cells to anticancer agents. Nat Med 2: 1204–1210, 1996
    PubMed CAS Google Scholar
87. St Croix B, Kerbel RS: Cell adhesion and drug resistance in cancer. Curr Opin Oncol 9: 549–556, 1997
    CAS PubMed Google Scholar
88. Day M, Zhao X, Vallorosi C, Putzi M, Powell C, Lin C, Day K: E-cadherin mediates aggregation-dependent survival of prostate and mammary epithelial cells through the retinoblastoma cell cycle control pathway. J Biol Chem 274: 9656–9664, 1999
    PubMed CAS Google Scholar
89. Khwaja A, Rodriguez-Viciana P, Wennstrom S, Warne PH, Downward J: Matrix adhesion and Ras transformation both activate a phosphoinositide 3-OH kinase and protein kinase B/Akt cellular survival pathway. Embo J 16: 2783–2793, 1997
    PubMed CAS Google Scholar
90. Rosen K, Rak J, Leung T, Dean NM, Kerbel RS, Filmus J: Activated Ras prevents downregulation of Bcl-X(L) triggered by detachment from the extracellular matrix. A mechanism of Ras-induced resistance to anoikis in intestinal epithelial cells. J Cell Biol 149: 447–456, 2000
    PubMed CAS Google Scholar
91. Jost M, Huggett TM, Kari C, Rodeck U: Matrix-independent survival of human keratinocytes through an EGF receptor/MAPK-kinase-dependent pathway. Mol Biol Cell 12: 1519–1527, 2001
    PubMed CAS Google Scholar
92. Tran NL, Adams DG, Vaillancourt RR, Heimark RL: Signal transduction from N-cadherin increases Bcl-2. Regulation of the phosphatidylinositol 3-kinase/Akt pathway by homophilic adhesion and actin cytoskeletal organization. J Biol Chem 277: 32905–32914, 2002
    PubMed CAS Google Scholar
93. Kantak SS, Kramer RH: E-cadherin regulates anchorage-independent growth and survival in oral squamous cell carcinoma cells. J Biol Chem 273: 16953–16961, 1998
    PubMed CAS Google Scholar
94. Shen X, Kramer RH: Adhesion-mediated squamous cell carcinoma survival through ligand-independent activation of epidermal growth factor receptor. Am J Pathol 165: 1315–1329, 2004
    PubMed CAS Google Scholar
95. Shinohara M, Kodama A, Matozaki T, Fukuhara A, Tachibana K, Nakanishi H, Takai Y: Roles of cell-cell adhesion-dependent tyrosine phosphorylation of Gab-1. J Biol Chem 276: 18941–18946, 2001
    PubMed CAS Google Scholar
96. Arregui C, Pathre P, Lilien J, Balsamo J: The nonreceptor tyrosine kinase fer mediates cross-talk between N-cadherin and beta1-integrins. J Cell Biol 149: 1263–1274, 2000
    PubMed CAS Google Scholar
97. Yamada K, Jordan R, Mori M, Speight PM: The relationship between E-cadherin expression, clinical stage and tumour differentiation in oral squamous cell carcinoma. Oral Dis 3: 82–85, 1997
    Article PubMed CAS Google Scholar
98. Todd R, Wong DT: Epidermal growth factor receptor (EGFR) biology and human oral cancer. Histol Histopathol 14: 491–500, 1999
    PubMed CAS Google Scholar
99. Bei R, Pompa G, Vitolo D, Moriconi E, Ciocci L, Quaranta M, Frati L, Kraus MH, Muraro R: Co-localization of multiple ErbB receptors in stratified epithelium of oral squamous cell carcinoma. J Pathol 195: 343–348, 2001
    PubMed CAS Google Scholar
100. Ruoslahti E: Fibronectin and its integrin receptors in cancer. Adv Cancer Res 76: 1–20, 1999
     Article PubMed CAS Google Scholar
101. Mahoney MG, Simpson A, Jost M, Noe M, Kari C, Pepe D, Choi YW, Uitto J, Rodeck U: Metastasis-associated protein (MTA)1 enhances migration, invasion, and anchorage-independent survival of immortalized human keratinocytes. Oncogene 21: 2161–2170, 2002
     PubMed CAS Google Scholar
102. Zhu Z, Sanchez-Sweatman O, Huang X, Wiltrout R, Khokha R, Zhao Q, Gorelik E: Anoikis and metastatic potential of cloudman S91 melanoma cells. Cancer Res 61: 1707–1716, 2001
     PubMed CAS Google Scholar
103. Swan EA, Jasser SA, Holsinger FC, Doan D, Bucana C, Myers JN: Acquisition of anoikis resistance is a critical step in the progression of oral tongue cancer. Oral Oncol 39: 648–655, 2003
     PubMed CAS Google Scholar

Download references