Influence of dietary supplementation with long-chain n−3 or n−6 polyunsaturated fatty acids on blood inflammatory cell populations and functions and on plasma soluble adhesion molecules in healthy adults (original) (raw)

References

  1. Abbas, A.K., Lichtman, A.H., and Pober, J.S. (1994) Cellular and Molecular Immunology, 2nd edn., W.B. Saunders, Philadelphia.
    Google Scholar
  2. Gearing, A.J.H., and Newman, W. (1993) Circulating Adhesion Molecules in Disease, Immunol. Today 14, 506–512.
    Article PubMed CAS Google Scholar
  3. Morisaki, N., Saito, I., Tamura, K., Tashiro, J., Masuda, M., Kanzaki, T., Watanabe, S., Masuda, Y., and Saito, Y. (1997) New Indices of Ischemic Heart Disease and Aging: Studies on the Serum Levels of Soluble Intercellular Adhesion Molecule-1 (ICAM-1) and Soluble Vascular Cell Adhesion Molecule-1 (VCAM-1) in Patients with Hypercholesterolemia and Ischemic Heart Disease, Artherosclerosis 131, 43–48.
    Article CAS Google Scholar
  4. Hwang, S-J., Ballantyne, C.M., Sharrett, A.R., Smith, L.C., Davis, C.E., Gotto, A.M., and Boerwinkle, E. (1997) Circulating Adhesion Molecules VCAM-1, ICAM-1, and E-Selectin in Carotid Atherosclerosis and Incident Coronary Heart Disease Cases, Circulation 96, 4219–4225.
    PubMed CAS Google Scholar
  5. Rohde, L.E.P., Hennekens, C.H., and Ridker, P.M. (1999) Cross-Sectional Study of Soluble Intercellular Adhesion Molecule-1 and Cardiovascular Risk Factors in Apparently Healthy Men, Arterioscler. Thromb. Vasc. Biol. 19, 1595–1599.
    PubMed CAS Google Scholar
  6. Haught, W.H., Mansour, M., Rothlein, R., Kishimoto, T.K., Mainolfi, E.A., Hendricks, J.B., Hendricks, C., and Mehta, J.L. (1996) Alterations in Circulating Intercellular Adhesion Molecule-1 and L-Selectin: Further Evidence for Chronic Inflammation in Ischemic Heart Disease, Am. Heart J. 132, 1–8.
    Article PubMed CAS Google Scholar
  7. Ridker, P.M., Hennekens, C.H., Roitman-Johnson, B., Stampfer, M.J., and Allen, J. (1998) Plasma Concentration of Soluble Intercellular Adhesion Molecule 1 and Risks of Future Myocardial Infarction in Apparently Healthy Men, Lancet 351, 88–92.
    Article PubMed CAS Google Scholar
  8. Badwey, J.A., Curnutte, J.T., and Karnovsky, M.L. (1981) _cis_-Polyunsaturated Fatty Acids Induce High Levels of Superoxide Production by Human Neutrophils, J. Biol. Chem. 256, 12640–12643.
    PubMed CAS Google Scholar
  9. Badwey, J.A., Curnutte, J.T., Robinson, J.M., Berde, C.B., Karnovsky, M.J., and Karnovsky, M.L. (1984) Effects of Free Fatty Acids on Release of Superoxide and on Change of Shape by Human Neutrophils, J. Biol. Chem. 259, 7870–7877.
    PubMed CAS Google Scholar
  10. Hardy, S.J., Robinson, B.S., Poulos, A., Harvey, D.P., Ferrante, A., and Murray, A.W. (1991) The Neutrophil Respiratory Burst: Response to Fatty Acids, _N_-Formylmethionylleucyl Phenylalanine and Phorbol Ester Suggest Divergent Signalling Mechanisms, Eur. J. Biochem. 198, 801–806.
    Article PubMed CAS Google Scholar
  11. Poulos, A., Robinson, B.S., Ferrante, A., Harvey, D.P., Hardy, S.J., and Murray, A.W. (1991) Effect of 22–32 Carbon n−3 Polyunsaturated Fatty Acids on Superoxide Production in Human Neutrophils: Synergism of Docosahexaenoic Acid with F-Met-Leu-Phe and Phorbol Ester, Immunology 73, 102–108.
    PubMed CAS Google Scholar
  12. Chen, L.Y., Lawson, D.L., and Mehta, J.L. (1994) Reduction in Human Neutrophil Superoxide Anion Generation by n−3 Polyunsaturated Fatty Acids: Role of Cyclooxygenase Products and Endothelium-Derived Relaxing Factor, Thromb. Res. 76, 317–322.
    Article PubMed CAS Google Scholar
  13. Baldie, G., Kaimakamis, D., and Rotondo, D. (1993) Fatty Acid Modulation of Cytokine Release from Human Monocytic Cells, Biochim. Biophys. Acta 1179, 125–133.
    Article PubMed CAS Google Scholar
  14. Sinha, B., Stoll, D., Weber, P.C., and Endres, S. (1991) Polyunsaturated Fatty Acids Modulate the Synthesis of TNF-α and Interleukin-1β by Human Mononuclear Cells in vitro, Cytokine 3, 475.
    Article Google Scholar
  15. Purasiri, P., McKechnie, A., Heys, S.D., and Eremin, O. (1997) Modulation in vitro of Human Natural Cytotoxicity, Lymphocyte Proliferative Response to Mitogens and Cytokine Production by Essential Fatty Acids, Immunology 92, 166–172.
    Article PubMed CAS Google Scholar
  16. de Caterina, R., Cybulsky, M.A., Clinton, S.K., Gimbrone, M.A., and Libby, P. (1994) The Omega-3 Fatty Acid Docosahexaenoate Reduces Cytokine-Induced Expression of Proatherogenic and Proinflammatory Proteins in Human Endothelial Cells, Arterioscler. Thromb. 14, 1826–1836.
    Google Scholar
  17. Khalfoun, B., Thibault, G., Bardos, P., and Lebranchu, Y. (1996) Docosahexaenoic and Eicosapentaenoic Acids Inhibit in vitro Human Lymphocyte-Endothelial Cell Adhesion, Transplantation 62, 1649–1657.
    Article PubMed CAS Google Scholar
  18. Weber, C., Erl, W., Pietsch, A., Danesch, U., and Weber, P.C. (1995) Docosahexaenoic Acid Selectively Attenuates Induction of Vascular Cell Adhesion Molecule-1 and Subsequent Monocytic Adhesion to Human Endothelial Cells Stimulated by Tumor Necrosis Factor-Alpha, Arterioscler. Thromb. Vasc. Biol. 15, 622–628.
    PubMed CAS Google Scholar
  19. Collie-Duguid, E.S.R., and Wahle, K.W.J. (1996) Inhibitory Effect of Fish Oil n−3 Polyunsaturated Fatty Acids on the Expression of Endothelial Cell Adhesion Molecules, Biochem. Biophys. Res. Commun. 220, 969–974.
    Article PubMed CAS Google Scholar
  20. Hughes, D.A., Southon, S., and Pinder, A.C. (1996) (n−3) Polyunsaturated Fatty Acids Modulate the Expression of Functionally Associated Molecules on Human Monocytes in vitro, J. Nutr. 126, 603–610.
    PubMed CAS Google Scholar
  21. Bates, E.J., Ferrante, A., Smithers, L., Poulos, A., and Robinson, B.S. (1995) Effect of Fatty Acid Structure on Neutrophil Adhesion, Degranulation and Damage to Endothelial Cells, Atherosclerosis 116, 247–259.
    Article PubMed CAS Google Scholar
  22. Fletcher, M.P., and Ziboh, V.A. (1990) Effects of Dietary Supplementation with Eicosapentaenoic Acid or Gamma-Linolenic Acid on Neutrophil Phospholipid Fatty Acid Composition and Activation Responses, Inflammation 14, 585–597.
    Article PubMed CAS Google Scholar
  23. Sassen, L.M.A., Lamers, J.M.J., Sluiter, W., Hartog, J.M., Dekkers, D.H.W., Hogendoorn, A., and Verdouw, P.D. (1993) Development and Regression of Atherosclerosis in Pigs—Effects of n−3 Fatty Acids, Their Incorporation into Plasma and Aortic Plaque Lipids, and Granulocyte Function, Arterioscler. Thromb. 13, 651–660.
    PubMed CAS Google Scholar
  24. D’Ambola, J.B., Aeberhard, E.E., Trang, N., Gaffar, S., Barrett, C.T., and Sherman, M.P. (1991) Effect of Dietary (n−3) and (n−6) Fatty Acids on in vivo Pulmonary Bacterial Clearance by Neonatal Rabbits, J. Nutr. 121, 1262–1269.
    PubMed CAS Google Scholar
  25. Joe, B., and Lokesh, B.R. (1994) Role of Capsaicin, Curcumin and Dietary n−3 Fatty Acids in Lowering the Generation of Reactive Oxygen Species in Rat Peritoneal Macrophages, Biochim. Biophys. Acta 1224, 255–263.
    Article PubMed CAS Google Scholar
  26. Eicher, S.D., and McVey, D.S. (1995) Dietary Modulation of Kupffer Cell and Splenocyte Function During a Salmonella typhimurium Challenge in Mice, J. Leuk. Biol. 58, 32–39.
    CAS Google Scholar
  27. Hubbard, N.E., Somers, S.D., and Erickson, K.L. (1991) Effect of Dietary Fish Oil on Development and Selected Functions of Murine Inflammatory Macrophages, J. Leuk. Biol. 49, 592–598.
    CAS Google Scholar
  28. Billiar, T., Bankey, P., Svingen, B., Curran, R.D., West, M.A., Holman, R.T., Simmons, R.L., and Cerra, F.B. (1988) Fatty Acid Uptake and Kupffer Cell Function: Fish Oil Alters Eicosanoid and Monokine Production to Endotoxin Stimulation, Surgery 104, 343–349.
    PubMed CAS Google Scholar
  29. Renier, G., Skamene, E., de Sanctis, J., and Radzioch, D. (1993) Dietary n−3 Polyunsaturated Fatty Acids Prevent the Development of Atherosclerotic Lesions in Mice: Modulation of Macrophage Secretory Activities, Arterioscler. Thromb. 13, 1515–1524.
    PubMed CAS Google Scholar
  30. Yaqoob, P., and Calder, P.C. (1995) Effects of Dietary Lipid Manipulation upon Inflammatory Mediator Production by Murine Macrophages, Cell. Immunol. 163, 120–128.
    Article PubMed CAS Google Scholar
  31. Wallace, F.A., Miles, E.A., and Calder, P.C. (2000) Activation State Alters the Effect of Dietary Lipids on Pro-inflammatory Mediator Production by Murine Macrophages, Cytokine 12, 1374–1379.
    Article PubMed CAS Google Scholar
  32. Grimm, H., Tibell, A., Norrlind, B., Blecher, C., Wilker, S., and Schwemmle, K. (1994) Immunoregulation by Parenteral Lipids: Impact of the n−3 to n−6 Fatty Acid Ratio, J. Parent. Ent. Nutr. 18, 417–421.
    Article CAS Google Scholar
  33. Thompson, P.J., Misso, N.L.A., Passarelli, M., and Phillips, M.J. (1991) The Effect of Eicosapentaenoic Acid Consumption on Human Neutrophil Chemiluminescence, Lipids 26, 1223–1226.
    PubMed CAS Google Scholar
  34. Luostarinen, R., and Saldeen, T. (1996) Dietary Fish Oil Decreases Superoxide Generation by Human Neutrophils: Relation to Cyclooxygenase Pathway and Lysosomal Enzyme Release, Prostaglandins Leukotrienes Essent. Fatty Acids 55, 167–172.
    Article CAS Google Scholar
  35. Varming, K., Schmidt, E.B., Svaneborg, N., Moller, J.M., Lervang, H.H., Grunnet, N., Jersild, C., and Dyerberg, J. (1995) The Effect of n−3 Fatty Acids on Neutrophil Chemiluminescence, Scand. J. Clin. Lab. Invest. 55, 47–52.
    PubMed CAS Google Scholar
  36. Fisher, M., Levine, P.H., Weiner, B.H., Johnson, M.H., Doyle, E.M., Ellis, P.A., and Hoogasian, J.J. (1990) Dietary n−3 Fatty Acid Supplementation Reduces Superoxide Production and Chemiluminescence in a Monocyte-Enriched Preparation of Leukocytes, Am. J. Clin. Nutr. 51, 804–808.
    PubMed CAS Google Scholar
  37. Lee, T.H., Hoover, R.L., Williams, J.D., Sperling, R.I., Ravalese, J., Spur, B.W., Robinson, D.R., Corey, E.J., Lewis, R.A., and Austen, K.F. (1985) Effects of Dietary Enrichment with Eicosapentaenoic Acid and Docosahexaenoic Acid on in vitro Neutrophil and Monocyte Leukotriene Generation and Neutrophil Function, New Engl. J. Med. 312, 1217–1224.
    Article PubMed CAS Google Scholar
  38. Caughey, G.E., Mantzioris, E., Gibson, R.A., Cleland, L.G., and James, M.J. (1996) The Effect on Human Tumor Necrosis Factor α and Interleukin 1β Production of Diets Enriched in n−3 Fatty Acids from Vegetable Oil or Fish Oil, Am. J. Clin. Nutr. 63, 116–122.
    PubMed CAS Google Scholar
  39. Endres, S., Ghorbani, R., Kelley, V.E., Georgilis, K., Lonnemann, G., van der Meer, J.M.W., Cannon, J.G., Rogers, T.S., Klempner, M.S., Weber, P.C., Schaeffer, E.J., Wolff, S.M., and Dinarello, C.A. (1989) The Effect of Dietary Supplementation with n−3 Polyunsaturated Fatty Acids on the Synthesis of Interleukin-1 and Tumor Necrosis Factor by Mononuclear Cells, New Engl. J. Med. 320, 265–271.
    Article PubMed CAS Google Scholar
  40. Meydani, S.N., Endres, S., Woods, M.M., Goldin, B.R., Soo, C., Morrill-Labrode, A., Dinarello, C., and Gorbach, S.L. (1991) Oral (n−3) Fatty Acid Supplementation Suppresses Cytokine Production and Lymphocyte Proliferation: Comparison Between Young and Older Women, J. Nutr. 121, 547–555.
    PubMed CAS Google Scholar
  41. Gallai, V., Sarchielli, P., Trequattrini, A., Franceschini, M., Floridi, A., Firenze, C., Alberti, A., Di Benedetto, D., and Stragliotto, E. (1993) Cytokine Secretion and Eicosanoid Production in the Peripheral Blood Mononuclear Cells of Multiple Sclerosis Patients Undergoing Dietary Supplementation with n−3 Polyunsaturated Fatty Acids, J. Neuroimmunol. 56, 143–153.
    Article Google Scholar
  42. Calder, P.C., Bond, J.A., Harvey, D.J., Gordon, S., and Newsholme, E.A. (1990) Uptake of Saturated and Unsaturated Fatty Acids into Macrophage Lipids and Their Effect upon Macrophage Adhesion and Phagocytosis, Biochem. J. 269, 807–814.
    PubMed CAS Google Scholar
  43. British Nutrition Foundation (1992) Report of the Task Force on Unsaturated Fatty Acids—Nutritional and Physiological Significance, Chapman and Hall, London.
    Google Scholar
  44. British Nutrition Foundation (1999) Briefing Paper: n−3 Fatty Acids and Health, British Nutrition Foundation, London.
    Google Scholar
  45. de Deckere, E.A.M., Korver, O., Verschuren, P.M., and Katan, M.B. (1998) Health Aspects of Fish and n−3 Polyunsaturated Fatty Acids from Plant and Marine Origin, Eur. J. Clin. Nutr. 52, 749–753.
    Article PubMed CAS Google Scholar
  46. Forsythe, J.S., and Carlson, S.E. (2001) Long-Chain Polyunsaturated Fatty Acids in Infant Nutrition: Effects on Infant Development, Curr. Opin. Clin. Nutr. Metab. Care 4, 123–126.
    Google Scholar
  47. Kelley, D.S., Taylor, P.C., Nelson, G.J., and Mackey, B.E. (1998) Dietary Docosahexaenoic Acid and Immunocompetence in Young Healthy Men, Lipids 33, 559–566.
    PubMed CAS Google Scholar
  48. Kelley, D.S., Taylor, P.C., Nelson, G.J., Schmidt, P.C., Ferretti, A., Erickson, K.L., Yu, R., Chandra, R.K., and Mackey, B.E. (1999) Docosahexaenoic Acid Ingestion Inhibits Natural Killer Cell Activity and Production of Inflammatory mediators in Young Healthy Men, Lipids 34, 317–324.
    PubMed CAS Google Scholar
  49. Kelley, D.S., Taylor, P.C., Nelson, G.J., Schmidt, P.C., Mackey, B.E., and Kyle, D. (1997) Effects of Dietary Arachidonic Acid on Human Immune Response, Lipids 32, 449–456.
    PubMed CAS Google Scholar
  50. Thies, F., Nebe-von-Caron, G., Powell, J.R., Yaqoob, P., Newsholme, E.A., and Calder, P.C. (2001) Dietary Supplementation with Eicosapentaenoic Acid, but Not with Other Long-Chain n−3 or n−6 Polyunsaturated Fatty Acids, Decreases Natural Killer Cell Activity in Healthy Subjects Aged>55 Years, Am. J. Clin. Nutr. 73, 539–548.
    PubMed CAS Google Scholar
  51. Thies, F., Nebe-von-Caron, G., Powell, J.R., Yaqoob, P., Newsholme, E.A., and Calder, P.C. (2001) Dietary Supplementation with γ-Linolenic Acid or with Fish Oil Decreases T Lymphocyte Proliferation in Healthy Older Humans, J. Nutr. 131, 1918–1927.
    PubMed CAS Google Scholar
  52. Kelley, D.S., Branch, L.B., Love, J.E., Taylor, P.C., Rivera, Y.M., and Iacono, J.M. (1991) Dietary Alpha-Linolenic Acid and Immunocompetence in Humans, Am. J. Clin. Nutr. 53, 40–46.
    PubMed CAS Google Scholar
  53. Halvorsen, D.A., Hansen, J-B., Grimsgaard, S., Bonaa, K.H., Kierulf, P., and Nordoy, A. (1997) The Effect of Highly Purified Eicosapentaenoic and Docosahexaenoic Acids on Monocyte Phagocytosis in Man, Lipids 32, 935–942.
    PubMed CAS Google Scholar
  54. Schmidt, E.B., Varming, K., Moller, J.M., Bulow Pederson, I., Madsen, P., and Dyerberg, J. (1996) No Effect of a Very Low Dose of n−3 Fatty Acids on Monocyte Function in Healthy Humans, Scand. J. Clin. Invest. 56, 87–92.
    PubMed CAS Google Scholar
  55. Kelley, D.S., Taylor, P.C., Nelson, G.J., and Mackey, B.E. (1998) Arachidonic Acid Supplementation Enhances Synthesis of Eicosanoids Without Suppressing Immune Functions in Young Healthy Men, Lipids 33, 125–130.
    PubMed CAS Google Scholar
  56. Wu, D., Meydani, M., Leka, L.S., Nightingale, Z., Handelman, G.J., Blumberg, J.B., and Meydani, S.N. (1999) Effect of Dietary Supplementation with Black Currant Seed Oil on the Immune Response of Healthy Elderly Subjects, Am. J. Clin. Nutr. 70, 536–543.
    PubMed CAS Google Scholar
  57. Cooper, A.L., Gibbons, L., Horan, M.A., Little, R.A., and Rothwell, N.J. (1993) Effect of Dietary Fish Oil Supplementation on Fever and Cytokine Production in Human Volunteers, Clin. Nutr. 12, 321–328.
    Article PubMed CAS Google Scholar
  58. Molvig, J., Pociot, F., Worsaae, H., Wogensen, L.D., Baek, L., Christensen, P., Mandrup-Poulsen, T., Andersen, K., Madsen, P., Dyerberg, J., and Nerup, J. (1991) Dietary Supplementation with ω−3 Polyunsaturated Fatty Acids Decreases Mononuclear Cell Proliferation and Interleukin-1β Content but Not Monokine Secretion in Healthy and Insulin-Dependent Diabetic Individuals, Scand. J. Immunol. 34, 399–410.
    Article PubMed CAS Google Scholar

Download references