Emmanuel G Ciolac | São Paulo State University (original) (raw)

Papers by Emmanuel G Ciolac

Research paper thumbnail of Efeito agudo do exercício resistido, aeróbio contínuo e intervalado na pressão intraocular de indivíduos fisicamente ativos

Ensaios e Ciência: Ciências Biológicas, Agrárias e da Saúde, 2012

Research paper thumbnail of Prescribing and Self-Regulating Heated Water-Based Exercise by Rating of Perceived Exertion in Older Individuals With Hypertension

Journal of Aging and Physical Activity, Oct 1, 2022

We aimed to analyze the usefulness of the 6–20 rating of perceived exertion (RPE) scale for presc... more We aimed to analyze the usefulness of the 6–20 rating of perceived exertion (RPE) scale for prescribing and self-regulating high-intensity interval (HIIE) and moderate-intensity continuous (MICE) aerobic exercise performed in a heated swimming pool (32 °C). Fifteen older individuals (65 ± 3 years) treated for hypertension underwent a symptom-limited maximal graded exercise test to determine their heart rate at anaerobic threshold, and respiratory compensation point. On different days, participants were randomized to HIIE (walking/jogging between 11 and 17 of RPE; 25 min) and MICE (walking at 11–13 of RPE; 30 min). Heart rate during the low-intensity intervals of HIIE and MICE remained below the graded exercise test’s heart rate at anaerobic threshold (−7 ± 18 bpm/−16 ± 15 bpm) and respiratory compensation point (−18 ± 18 bpm/−30 ± 16 bpm), respectively, and maintained in the aerobic training zone during the high-intensity intervals of HIIE (+8 ± 18 bpm/−4 ± 19 bpm). The RPE scale at 15–17 is a useful tool for prescribing and self-regulating heated water-based HIIE and may have important implications for water-based exercise in older individuals with hypertension.

Research paper thumbnail of Síndrome metabólica: abordagem do educador físico

Rev. Soc. Cardiol. Estado de Säo Paulo, 2004

Page 1. Rev Soc Cardiol Estado de São Paulo — Vol 14 — No 4 — Julho/Agosto de 2004 659 GUIMARÃES ... more Page 1. Rev Soc Cardiol Estado de São Paulo — Vol 14 — No 4 — Julho/Agosto de 2004 659 GUIMARÃES GV e col. Síndrome metabólica: abordagem do educador físico INTRODUÇÃO A prática regular de atividade física ...

Research paper thumbnail of Factors Associated With Levels of Physical Activity in Chronic Kidney Disease Patients Undergoing Hemodialysis: The Role of Dialysis Versus Nondialysis Day

Journal of Physical Activity and Health, Sep 1, 2017

patients on hemodialysis (HD) report lower physical activity (PA) levels. We analysed factors ass... more patients on hemodialysis (HD) report lower physical activity (PA) levels. We analysed factors associated with low levels of PA in patients with chronic kidney disease (CKD) and compared PA on HD day and non-HD. 79 patients wore an accelerometer and were classified according to time spent on moderate-vigorous PA (MVPA). Demographic data, BMI, comorbidities, clinical status and health related quality of life (HRQoL) were checked for association with PA. Also, PA level was compared between days of HD and non-HD. Accelerometer compliance was 78.5%, 33 men and 29 women (53.96±15.71 yrs) were included in analysis. 35.5% of sample achieved ≥150min/week on MVPA. Lower MVPA was associated with older age (OR=5.80, 95%CI=1.11-30.19, p=0.04), and lower score of physical function HRQoL (OR=4.33, 95%CI=1.23-15.23, p=0.02). Additionally, patients spent 9.73% more time on sedentary behavior, 38.9% less on light PA and 74.9% less on MVPA on HD day vs non-HD day. Age and physical function HRQoL were the main factors associated to lower PA levels. In addition, lower time spent on PA during HD day suggest that strategies for increasing physical activity levels during HD day such exercising during HD session could help CKD patients to reach current PA recommendations.

Research paper thumbnail of Stress and Mood States Monitoring in a Swimming Team During a Competitive Period

Journal of Physical Education and Sport, Dec 1, 2018

The present study aims to identify and analyze stress levels, mood state, as well as the percepti... more The present study aims to identify and analyze stress levels, mood state, as well as the perception of stress and recovery of 32 athletes of both genders, swimmers. In order to quantitatively evaluate the variables the following instruments were used: the Recovery-Stress Questionnaire for Athletes (REST-Q) which describes the mental, emotional and physical well-being of the athletes, the Brunel Mood State Scale (BRUMS) which allows a rapid measurement of mood in populations composed by adults and adolescents and Foster Perception Subjective Effort (PSE) which aims to identify in a quick and simple way of how the practitioners of a certain activity comprises the effort accomplished during the proposed task. The results showed that in the first moments the athletes were in a high mood, which indicates an excellent performance for competitions, later it is possible to notice a reduction in the values of vigor and increase in the other variables, leading the athletes to an imbalance in the standard of the state of mood. Values obtained on the stress and recovery scale changed during the season, with stress indexes increased, while recovery values reduced, indicating susceptibility to injuries and overtire. In this way, the conclusion is that athletes have become more likely to have harmful and overtraining frames over time, thus it is necessary to monitor athlete workloads and perceptions. To better understanding, the states of mood it is necessary to know the athlete deeply and the context which he is present in.

Research paper thumbnail of Determinants of endothelial dysfunction in noncritically ill hospitalized COVID‐19 patients: A cross‐sectional study

Obesity, 2021

Abstract Objective The aim of this study was to identify determinants of endothelial dysfunction ... more Abstract Objective The aim of this study was to identify determinants of endothelial dysfunction in patients hospitalized with acute COVID‐19. Methods A total of 109 hospitalized COVID‐19 patients in noncritical status were cross‐sectionally studied. Clinical data (age, sex, comorbidities, and medications) and BMI were assessed. Laboratory tests included serum hemoglobin, leukocytes, lymphocytes, platelets, C‐reactive protein, ferritin, D‐dimer, and creatinine. Physical status was evaluated using a handgrip dynamometer. Endothelial function was assessed noninvasively using the flow‐mediated dilation (FMD) method. Results The sample average age was 51 years, 51% of patients were male, and the most frequent comorbidity was obesity (62%). Univariate analysis showed association of lower FMD with higher BMI, hypertension, use of oral antihypertensive, higher blood levels of creatinine, and larger baseline artery diameter. After adjusting for confounders, the multivariate analysis showed BMI (95% CI: −0.26 to −0.11; p < 0.001) as the major factor associated with FMD. Other factors associated with FMD were baseline artery diameter (95% CI: −1.77 to −0.29; p = 0.007) and blood levels of creatinine (95% CI: −1.99 to −0.16; p = 0.022). Conclusions Increased BMI was the major factor associated with endothelial dysfunction in noncritically hospitalized COVID‐19 patients. This may explain one of the pathways in which obesity may increase the risk for severe COVID‐19.

Research paper thumbnail of Effects of High-Intensity Interval vs. Continuous Moderate Exercise on Intraocular Pressure

International Journal of Sports Medicine, 2014

Our purpose was to compare the acute effects of high-intensity interval training (HIT) vs. contin... more Our purpose was to compare the acute effects of high-intensity interval training (HIT) vs. continuous moderate exercise (CME) on intraocular pressure (IOP) in healthy subjects. Fifteen young men (age=22.1±6 years) underwent 30 min of HIT (2 min of walking at 50% of reserve heart rate (HR) alternated with 1 min of running at 80% of reserve HR) and CME sessions (30 min of jogging/running at 60% of reserve HR) in random order (2-5 days between sessions). IOP was measured before (baseline), immediately after (post--exercise), 5 min after (Rec5) and 10 min after (Rec10) each exercise session. IOP was reduced post-exercise and remained reduced at Rec5 during both HIT and CME session, with no significant difference between interventions (~16% between 23%). However, IOP remained reduced at Rec10 only after HIT intervention (~19%), whereas IOP at Rec10 returned to levels similar to the observed at baseline during CME intervention. In summary, both HIT and CME equally reduced IOP immediately and 5 min after exercise session. However, only HIT was able to remain IOP reduced 10 min after exercise. These results suggest that HIT may be more effective than CME for reducing IOP in young healthy men.

Research paper thumbnail of Virtual Reality Therapy: motor coordination and balance analysis in children and teenagers with Down syndrome

European Journal of Human Movement, 2017

Introduction: The aim of the study was to evaluate the effects of Virtual Reality Therapy on moto... more Introduction: The aim of the study was to evaluate the effects of Virtual Reality Therapy on motor coordination and balance of children and adolescents with Down Syndrome. Material and Methods: It is an analytical, prospective and quantitative study. This study included 12 participants were divided into two groups, five of them were part of the Control Group which performed regular institution activities, and the Protocol Group was composed of seven individuals who participated in the Virtual Reality Therapy program and also performed regular institution activities. First, the participants underwent an anthropometric assessment, Korperkoordinatonstest Fur Kinder and Pediatric Balance Scale. The Virtual Reality Therapy program consisted of 16 sessions of 20 minutes each. After the program the participants were reassessed. Results and Discussion: There was a statistically significant increase, with p<0.05 in motor coordination of Protocol Group. The balance increase was also statis...

Research paper thumbnail of Analysis of Cardiovascular Hemodynamic and Autonomic Variables in Individuals with Systemic Arterial Hypertension, Type 2 Diabetes Mellitus, and Parkinson’s Disease: A Comparative Study

Clinical and Experimental Hypertension, Dec 8, 2021

ABSTRACT Background Systemic arterial hypertension (SAH), type 2 diabetes mellitus (T2DM), and Pa... more ABSTRACT Background Systemic arterial hypertension (SAH), type 2 diabetes mellitus (T2DM), and Parkinson’s disease (PD) are highly prevalent chronic diseases that can significantly impact the cardiovascular system. Aim The aim of this study was to compare hemodynamic and autonomic variables at rest in individuals with SAH, T2DM, or PD. Methods Fifty sedentary or insufficiently active individuals (22 men) with SAH (age = 66 ± 5.0 yr), T2DM (age = 52 ± 10 yr) or PD (age = 68 ± 8.0 yr) had their resting blood pressure (BP), arterial stiffness, endothelial function, and heart rate variability (HRV) assessed and compared. Results Systolic and diastolic BP were higher in SAH (130 ± 10 / 80 ± 10 mmHg) than T2DM (110 ± 14 / 75 ± 11 mmHg) and PD, and (123 ± 20 / 70 ± 11 mmHg) respectively. T2DM individuals showed lower arterial stiffness (8.4 ± 1.1 m/s), when compared to SAH (10.3 ± 2.3 m/s) and PD (10.6 ± 3.0 m/s). T2DM had greater resting tachycardia showed by the mean RR (759 ± 79 ms), than SAH (962 ± 169 ms) and PD (976 ± 134 ms), which was accompanied by higher sympathetic modulation (low frequency [LF]: 62 ± 19 nu) and lower parasympathetic modulation (high frequency [HF]: 32 ± 16 nu) when compared to SAH (LF: 40 ± 16 nu; HF: 61 ± 33 nu). No differences among groups were found on non-linear HRV markers and endothelial reactivity indexes. Conclusions Individuals with T2DM showed impaired levels of cardiac autonomic markers when compared to individuals with SAH and PD, despite of having lower levels of BP and arterial stiffness.

Research paper thumbnail of Characterizing the interindividual postexercise hypotension response for two order groups of concurrent training in patients with morbid obesity

Frontiers in Physiology

Background: Postexercise hypotension (PEH) is a common physiological phenomenon occurring immedia... more Background: Postexercise hypotension (PEH) is a common physiological phenomenon occurring immediately after endurance training (ET), resistance training (RT), and ET plus RT, also termed concurrent training (CT); however, there is little knowledge about the interindividual and magnitude response of PEH in morbidly obese patients.Aim: The aims of this study were (1) to investigate the effect of CT order (ET + RT vs. RT + ET) on the blood pressure responses; 2) characterize these responses in responders and nonresponders, and 3) identify potential baseline outcomes for predicting blood pressure decreases as responders.Methods: A quasi-experimental study developed in sedentary morbidly obese men and women (age 43.6 ± 11.3 years; body mass index [BMI] ≥40 kg/m2) was assigned to a CT group of ET plus RT (ET + RT; n = 19; BMI 47.8 ± 16.7) or RT plus ET order group (RT + ET; n = 17; BMI 43.0 ± 8.0). Subjects of both groups received eight exercise sessions over four weeks. Primary outcomes ...

Research paper thumbnail of Contemporary review of exercise in heart transplant recipients

Transplantation Reviews, 2021

Heart transplantation (HTx) is a therapeutic option for a selected group of patients with end-sta... more Heart transplantation (HTx) is a therapeutic option for a selected group of patients with end-stage heart failure. Although secondary prevention including exercise therapy is recommended in the management of patients following HTx, little information is available on their metabolic and physiological consequences in HTx. Therefore, we aimed to conduct a contemporary review the effectiveness of exercise therapy on functional capacity, cardiovascular health and health-related quality of life for adult HTx patients. We searched the database MEDLINE for articles published between January 2015 and October 2020 and were able to include 6 studies involving 202 patients. Larger improvements in exercise capacity were seen after high-intensity interval training and in patients with evidence of cardiac reinnervation. Clinically relevant reductions were observed for daytime and 24 h ambulatory blood pressure after exercise training and following a single bout of aerobic exercise. Finally, limited data suggest that quality of life is higher in HTx patients following high-intensity training. In summary, the available evidence shows the potential for exercise as a vital treatment in patients following HTx. Yet, the scant data calls for more well-designed and adequately powered studies to support its effectiveness and to unravel optimal exercise characteristics, which would allow for more effective and person-tailored exercise prescription.

Research paper thumbnail of Residual Impact of Concurrent, Resistance, and High-Intensity Interval Training on Fasting Measures of Glucose Metabolism in Women With Insulin Resistance

Frontiers in Physiology, 2021

We sought to assess the residual effects (post 72-h training cessation) on fasting plasma glucose... more We sought to assess the residual effects (post 72-h training cessation) on fasting plasma glucose (FPG) and fasting insulin (FI) after 12-weeks of high-intensity interval training (HIIT), resistance training (RT), or concurrent training (CT) in women with insulin resistance (IR). We also aimed to determine the training-induced, post-training residual impact of CT. A total of adult 45 women (age 38.5±9.2years) were included in the final analysis and were assigned to a control (CG; n=13, BMI 28.3±3.6kg/m2), HIIT [n=14, BMI 28.6±3.6kg/m2, three sessions/wk., 80–100% of the maximum heart rate (HRmax)], RT [n=8, BMI 29.4±5.5kg/m2, two sessions/wk., 8–10 points of the modified Borg, corresponding to 20 to 50% range of one maximum repetition test (1RM)], or CT group (n=10, BMI 29.1±3.0kg/m2, three sessions/wk., 80–100% of HRmax, and 8–10 Borg, or 20 to 50% range of 1RM, to each HIIT and RT compounds), with the latter including both HIIT and RT regimens. Training interventions lasted 12-wee...

Research paper thumbnail of Short-term community-based exercise programs in low-income older women: Does exercise intensity and modality matters?

Experimental Gerontology, 2021

Our aim was to evaluate the effect of community-based exercise program (CBEP) intensity and modal... more Our aim was to evaluate the effect of community-based exercise program (CBEP) intensity and modality on anthropometric, hemodynamic, and functional capacity parameters in low-income older women. Forty insufficiently active older women (68.2 ± 7.9 years) were randomly assigned to perform 12 weeks of twice-weekly high-intensity interval training combined with resistance training (HIIT+RT/n = 12), moderate-intensity continuous training combined with resistance training (MICT+RT/n = 13), or resistance training alone (RT/n = 15). Anthropometric (body mass index and waist circumference), hemodynamic (blood pressure and heart rate), and functional capacity variables (flexibility, upper and lower limb muscle strength, and mobility) were assessed before and after training programs. Waist circumference reduced similarly after all CBEP (~3 to ~4 cm; P < 0.05). However, tendency toward reduction in diastolic blood pressure (~4 mm Hg; P = 0.073), and improvements in flexibility (14.5%, P = 0.011) and handgrip strength (15.8%; P = 0.02) were found only in HIIT+RT. Indeed, only RT was effective to improve five-time sit to stand (14.1%; P = 0.013). However, no significant difference between groups was found during follow-up in any variable. The results of present study suggest that low-income older women may improve anthropometric, hemodynamic and functional capacity variables by participating in twice-weekly short-term (i.e.: 12 weeks) CBEP. However, the CBEP-effects on hemodynamic and functional capacity appears to be affected by exercise intensity (only HIIT+RT tended toward improving diastolic BP) and modality (only RT improved significantly five-time sit to stand), respectively.

Research paper thumbnail of Hypotensive Effect of Heated Water-Based Exercise Persists After 12-Week Cessation of Training in Patients With Resistant Hypertension

Canadian Journal of Cardiology, 2018

Keeping blood pressure levels within the normal range is a clinical challenge in patients with hy... more Keeping blood pressure levels within the normal range is a clinical challenge in patients with hypertension. Studies have shown favorable benefits of regular exercise in controlling blood pressure. However, the hypotensive effects of exercise return to pretraining of BP levels within 3 months after cessation of exercise. This study demonstrated that the effects of heated waterbased exercise on blood pressure persisted after 3 months of cessation of exercise in patients with resistant hypertension.

Research paper thumbnail of High-Intensity Interval Training as a Tool for Counteracting Dyslipidemia in Women

International journal of sports medicine, Jan 21, 2018

Sedentary overweight or obese adult (age<60 years) women, allocated in type 2 diabetes mellitu... more Sedentary overweight or obese adult (age<60 years) women, allocated in type 2 diabetes mellitus (T2DM,=13), dyslipidemia alone (DYS,=12), dyslipidemia associated with hyperglycaemia (DYSHG, N=12), or healthy control (CON,=10) groups, had their lipid, glucose, blood pressure, endurance performance, and anthropometry variables assessed before and after 16 weeks of a thrice-weekly high-intensity interval training (HIIT) program. Triglycerides reduced significantly (<0.05) in all groups, and high-density lipoprotein increased (<0.01) in T2DM, DYS and DYSHG; however, low-density lipoprotein reduced (<0.05) only in DYSHG, and total cholesterol reduced (<0.01) only in DYS and DYSHG. Fasting glucose reduced (<0.05) significantly in T2DM, DYS and DYSHG, but with higher decreases in T2DM and DYSHG. Blood pressure, endurance performance and body composition improved (<0.05) in all groups. The HIIT program was effective for restoring lipid profile of DYS and DYSHG, and fast...

Research paper thumbnail of Low-Volume High-Intensity Interval Training as a Therapy for Type 2 Diabetes

International Journal of Sports Medicine, 2016

Our purpose was to investigate the effects of low-volume, high-intensity interval training (HIT) ... more Our purpose was to investigate the effects of low-volume, high-intensity interval training (HIT) on cardiometabolic risk and exercise capacity in women with type 2 diabetes mellitus (T2DM). Sedentary overweight/obese T2DM women (age=44.5±1.8 years; BMI=30.5±0.6 kg/m(2)) were randomly assigned to a tri-weekly running-based HIT program (n=13) or non-exercise control follow-up (CON; n=10). Glycemic control, lipid and blood pressure levels, endurance performance, and anthropometry were measured before and after the follow-up (16 weeks) in both groups. Medication intake was also assessed throughout the follow-up. Improvements (P<0.05) on fasting glucose (14.3±1.4%), HbA1c (12.8±1.1%), systolic blood pressure (3.7±0.5 mmHg), HDL-cholesterol (21.1±2.8%), triglycerides (17.7±2.8%), endurance performance (9.8±1.0%), body weight (2.2±0.3%), BMI (2.1±0.3%), waist circumference (4.0±0.5%) and subcutaneous fat (18.6±1.4%) were found after HIT intervention. Patients of HIT group also showed reductions in daily dosage of antihyperglycemic and antihypertensive medication during follow-up. No changes were found in any variable of CON group. The HIT-induced improvements occurred with a weekly time commitment 56-25% lower than the minimal recommended in current guidelines. These findings suggest that low-volume HIT may be a time-efficient intervention to treat T2DM women.

Research paper thumbnail of Efeitos agudos do exercício resistido, aeróbio contínuo e intervalado na pressão intraocular de indivíduos fisicamente ativos e normotensos

Although not yet explored, evidence suggests that physical activity promotes reduction and contri... more Although not yet explored, evidence suggests that physical activity promotes reduction and contributes in a Intraocular Pressure (IOP) control. The aim was to investigate the acute effect of different types of exercise on IOP. Fifteen volunteers were randomly assigned to 3 sessions of 30 minutes of exercise: resistance exercises: 3 sets of 8 repetitions at 80% 1RM; continuous aerobic exercise: 60% of Heart Rate Reserve (HRR); Aerobic Interval Exercise: intercalating 2min 50% 1min and 80% of HRR. IOP was measured before (M1) for 15min (M2) and immediately after the session (M3), and during recovery: 5min (R1) and 10 minutes (R2). As ANOVA statistical procedure was used. There were significant reductions of IOP during all exercise sessions (M2 and M3). After exercise, IOP remained low until 5min on all models, however, at 10 minutes was lower than in M1 only in interval workout

Research paper thumbnail of Atividade Física Como Ferramenta De Promoção De Saúde

Research paper thumbnail of Muscular and Functional Capacity in Subjects Under Treatment for Knee Osteoarthritis: Role of Physical Activity Status

Journal of Physical Activity and Health, 2019

Background: The purpose of this study was to assess the role of physical activity (PA) in muscula... more Background: The purpose of this study was to assess the role of physical activity (PA) in muscular and functional capacity in subjects under treatment for knee osteoarthritis submitted to an interdisciplinary educational program emphasizing the regular practice of PA and exercises. Methods: Subjects under treatment for primary knee osteoarthritis (N = 136; age = 66 [3]) were allocated in sedentary to sedentary (SED-SED, sedentary or insufficiently active at pre and post), active to sedentary (ACT-SED, active or very active at pre and sedentary or insufficiently active at post), sedentary to active (SED-ACT, sedentary or insufficiently active at pre and active or very active at post), and active to active (ACT-ACT, active or very active at pre and post) groups. Muscular capacity (isokinetic test), functional capacity (timed up and down stairs test, timed up and go test, and 5 times sit to stand test), and daily living PA (International PA Questionnaire short version) were assessed before and after (12 mo) the follow-up. Results: There were improvements in performance (P < .05) in the time to up and down stairs: 37% in SED-ACT and 27.5% in ACT-ACT; timed up and go test: 33.5% in SED-ACT, 19% in ACT-SED, and 40% in ACT-ACT; 5 times sit to stand test: 39% in SED-ACT and 51% in ACT-ACT groups after 12 months of follow-up. Conclusions: The present results suggest that high levels of daily living PA may have an important role in the prevention/management of knee osteoarthritis.

Research paper thumbnail of Resistance Training as a Tool for Preventing and Treating Musculoskeletal Disorders

Sports Medicine, 2016

The aging process is characterized by several physiological, morphological, and psychological alt... more The aging process is characterized by several physiological, morphological, and psychological alterations that result in a decreased functional and health status throughout the life span. Among these alterations, the loss of muscle mass and strength (sarcopenia) is receiving increased attention because of its association with innumerous age-related disorders, including (but not limited to) osteoporosis, osteoarthritis, low back pain, risk of fall, and disability. Regular participation in resistance training programs can minimize the musculoskeletal alterations that occur during aging, and may contribute to the health and well-being of the older population. Compelling evidence suggest that regular practice of resistance exercise may prevent and control the development of several musculoskeletal chronic diseases. Moreover, resistance training may also improve physical fitness, function, and independence in older people with musculoskeletal disorders, which may result in improved quality of the years lived. In summary, regular participation in resistance training programs plays an important role in aging and may be a preventive and therapeutic tool for several musculoskeletal disorders.

Research paper thumbnail of Efeito agudo do exercício resistido, aeróbio contínuo e intervalado na pressão intraocular de indivíduos fisicamente ativos

Ensaios e Ciência: Ciências Biológicas, Agrárias e da Saúde, 2012

Research paper thumbnail of Prescribing and Self-Regulating Heated Water-Based Exercise by Rating of Perceived Exertion in Older Individuals With Hypertension

Journal of Aging and Physical Activity, Oct 1, 2022

We aimed to analyze the usefulness of the 6–20 rating of perceived exertion (RPE) scale for presc... more We aimed to analyze the usefulness of the 6–20 rating of perceived exertion (RPE) scale for prescribing and self-regulating high-intensity interval (HIIE) and moderate-intensity continuous (MICE) aerobic exercise performed in a heated swimming pool (32 °C). Fifteen older individuals (65 ± 3 years) treated for hypertension underwent a symptom-limited maximal graded exercise test to determine their heart rate at anaerobic threshold, and respiratory compensation point. On different days, participants were randomized to HIIE (walking/jogging between 11 and 17 of RPE; 25 min) and MICE (walking at 11–13 of RPE; 30 min). Heart rate during the low-intensity intervals of HIIE and MICE remained below the graded exercise test’s heart rate at anaerobic threshold (−7 ± 18 bpm/−16 ± 15 bpm) and respiratory compensation point (−18 ± 18 bpm/−30 ± 16 bpm), respectively, and maintained in the aerobic training zone during the high-intensity intervals of HIIE (+8 ± 18 bpm/−4 ± 19 bpm). The RPE scale at 15–17 is a useful tool for prescribing and self-regulating heated water-based HIIE and may have important implications for water-based exercise in older individuals with hypertension.

Research paper thumbnail of Síndrome metabólica: abordagem do educador físico

Rev. Soc. Cardiol. Estado de Säo Paulo, 2004

Page 1. Rev Soc Cardiol Estado de São Paulo — Vol 14 — No 4 — Julho/Agosto de 2004 659 GUIMARÃES ... more Page 1. Rev Soc Cardiol Estado de São Paulo — Vol 14 — No 4 — Julho/Agosto de 2004 659 GUIMARÃES GV e col. Síndrome metabólica: abordagem do educador físico INTRODUÇÃO A prática regular de atividade física ...

Research paper thumbnail of Factors Associated With Levels of Physical Activity in Chronic Kidney Disease Patients Undergoing Hemodialysis: The Role of Dialysis Versus Nondialysis Day

Journal of Physical Activity and Health, Sep 1, 2017

patients on hemodialysis (HD) report lower physical activity (PA) levels. We analysed factors ass... more patients on hemodialysis (HD) report lower physical activity (PA) levels. We analysed factors associated with low levels of PA in patients with chronic kidney disease (CKD) and compared PA on HD day and non-HD. 79 patients wore an accelerometer and were classified according to time spent on moderate-vigorous PA (MVPA). Demographic data, BMI, comorbidities, clinical status and health related quality of life (HRQoL) were checked for association with PA. Also, PA level was compared between days of HD and non-HD. Accelerometer compliance was 78.5%, 33 men and 29 women (53.96±15.71 yrs) were included in analysis. 35.5% of sample achieved ≥150min/week on MVPA. Lower MVPA was associated with older age (OR=5.80, 95%CI=1.11-30.19, p=0.04), and lower score of physical function HRQoL (OR=4.33, 95%CI=1.23-15.23, p=0.02). Additionally, patients spent 9.73% more time on sedentary behavior, 38.9% less on light PA and 74.9% less on MVPA on HD day vs non-HD day. Age and physical function HRQoL were the main factors associated to lower PA levels. In addition, lower time spent on PA during HD day suggest that strategies for increasing physical activity levels during HD day such exercising during HD session could help CKD patients to reach current PA recommendations.

Research paper thumbnail of Stress and Mood States Monitoring in a Swimming Team During a Competitive Period

Journal of Physical Education and Sport, Dec 1, 2018

The present study aims to identify and analyze stress levels, mood state, as well as the percepti... more The present study aims to identify and analyze stress levels, mood state, as well as the perception of stress and recovery of 32 athletes of both genders, swimmers. In order to quantitatively evaluate the variables the following instruments were used: the Recovery-Stress Questionnaire for Athletes (REST-Q) which describes the mental, emotional and physical well-being of the athletes, the Brunel Mood State Scale (BRUMS) which allows a rapid measurement of mood in populations composed by adults and adolescents and Foster Perception Subjective Effort (PSE) which aims to identify in a quick and simple way of how the practitioners of a certain activity comprises the effort accomplished during the proposed task. The results showed that in the first moments the athletes were in a high mood, which indicates an excellent performance for competitions, later it is possible to notice a reduction in the values of vigor and increase in the other variables, leading the athletes to an imbalance in the standard of the state of mood. Values obtained on the stress and recovery scale changed during the season, with stress indexes increased, while recovery values reduced, indicating susceptibility to injuries and overtire. In this way, the conclusion is that athletes have become more likely to have harmful and overtraining frames over time, thus it is necessary to monitor athlete workloads and perceptions. To better understanding, the states of mood it is necessary to know the athlete deeply and the context which he is present in.

Research paper thumbnail of Determinants of endothelial dysfunction in noncritically ill hospitalized COVID‐19 patients: A cross‐sectional study

Obesity, 2021

Abstract Objective The aim of this study was to identify determinants of endothelial dysfunction ... more Abstract Objective The aim of this study was to identify determinants of endothelial dysfunction in patients hospitalized with acute COVID‐19. Methods A total of 109 hospitalized COVID‐19 patients in noncritical status were cross‐sectionally studied. Clinical data (age, sex, comorbidities, and medications) and BMI were assessed. Laboratory tests included serum hemoglobin, leukocytes, lymphocytes, platelets, C‐reactive protein, ferritin, D‐dimer, and creatinine. Physical status was evaluated using a handgrip dynamometer. Endothelial function was assessed noninvasively using the flow‐mediated dilation (FMD) method. Results The sample average age was 51 years, 51% of patients were male, and the most frequent comorbidity was obesity (62%). Univariate analysis showed association of lower FMD with higher BMI, hypertension, use of oral antihypertensive, higher blood levels of creatinine, and larger baseline artery diameter. After adjusting for confounders, the multivariate analysis showed BMI (95% CI: −0.26 to −0.11; p < 0.001) as the major factor associated with FMD. Other factors associated with FMD were baseline artery diameter (95% CI: −1.77 to −0.29; p = 0.007) and blood levels of creatinine (95% CI: −1.99 to −0.16; p = 0.022). Conclusions Increased BMI was the major factor associated with endothelial dysfunction in noncritically hospitalized COVID‐19 patients. This may explain one of the pathways in which obesity may increase the risk for severe COVID‐19.

Research paper thumbnail of Effects of High-Intensity Interval vs. Continuous Moderate Exercise on Intraocular Pressure

International Journal of Sports Medicine, 2014

Our purpose was to compare the acute effects of high-intensity interval training (HIT) vs. contin... more Our purpose was to compare the acute effects of high-intensity interval training (HIT) vs. continuous moderate exercise (CME) on intraocular pressure (IOP) in healthy subjects. Fifteen young men (age=22.1±6 years) underwent 30 min of HIT (2 min of walking at 50% of reserve heart rate (HR) alternated with 1 min of running at 80% of reserve HR) and CME sessions (30 min of jogging/running at 60% of reserve HR) in random order (2-5 days between sessions). IOP was measured before (baseline), immediately after (post--exercise), 5 min after (Rec5) and 10 min after (Rec10) each exercise session. IOP was reduced post-exercise and remained reduced at Rec5 during both HIT and CME session, with no significant difference between interventions (~16% between 23%). However, IOP remained reduced at Rec10 only after HIT intervention (~19%), whereas IOP at Rec10 returned to levels similar to the observed at baseline during CME intervention. In summary, both HIT and CME equally reduced IOP immediately and 5 min after exercise session. However, only HIT was able to remain IOP reduced 10 min after exercise. These results suggest that HIT may be more effective than CME for reducing IOP in young healthy men.

Research paper thumbnail of Virtual Reality Therapy: motor coordination and balance analysis in children and teenagers with Down syndrome

European Journal of Human Movement, 2017

Introduction: The aim of the study was to evaluate the effects of Virtual Reality Therapy on moto... more Introduction: The aim of the study was to evaluate the effects of Virtual Reality Therapy on motor coordination and balance of children and adolescents with Down Syndrome. Material and Methods: It is an analytical, prospective and quantitative study. This study included 12 participants were divided into two groups, five of them were part of the Control Group which performed regular institution activities, and the Protocol Group was composed of seven individuals who participated in the Virtual Reality Therapy program and also performed regular institution activities. First, the participants underwent an anthropometric assessment, Korperkoordinatonstest Fur Kinder and Pediatric Balance Scale. The Virtual Reality Therapy program consisted of 16 sessions of 20 minutes each. After the program the participants were reassessed. Results and Discussion: There was a statistically significant increase, with p<0.05 in motor coordination of Protocol Group. The balance increase was also statis...

Research paper thumbnail of Analysis of Cardiovascular Hemodynamic and Autonomic Variables in Individuals with Systemic Arterial Hypertension, Type 2 Diabetes Mellitus, and Parkinson’s Disease: A Comparative Study

Clinical and Experimental Hypertension, Dec 8, 2021

ABSTRACT Background Systemic arterial hypertension (SAH), type 2 diabetes mellitus (T2DM), and Pa... more ABSTRACT Background Systemic arterial hypertension (SAH), type 2 diabetes mellitus (T2DM), and Parkinson’s disease (PD) are highly prevalent chronic diseases that can significantly impact the cardiovascular system. Aim The aim of this study was to compare hemodynamic and autonomic variables at rest in individuals with SAH, T2DM, or PD. Methods Fifty sedentary or insufficiently active individuals (22 men) with SAH (age = 66 ± 5.0 yr), T2DM (age = 52 ± 10 yr) or PD (age = 68 ± 8.0 yr) had their resting blood pressure (BP), arterial stiffness, endothelial function, and heart rate variability (HRV) assessed and compared. Results Systolic and diastolic BP were higher in SAH (130 ± 10 / 80 ± 10 mmHg) than T2DM (110 ± 14 / 75 ± 11 mmHg) and PD, and (123 ± 20 / 70 ± 11 mmHg) respectively. T2DM individuals showed lower arterial stiffness (8.4 ± 1.1 m/s), when compared to SAH (10.3 ± 2.3 m/s) and PD (10.6 ± 3.0 m/s). T2DM had greater resting tachycardia showed by the mean RR (759 ± 79 ms), than SAH (962 ± 169 ms) and PD (976 ± 134 ms), which was accompanied by higher sympathetic modulation (low frequency [LF]: 62 ± 19 nu) and lower parasympathetic modulation (high frequency [HF]: 32 ± 16 nu) when compared to SAH (LF: 40 ± 16 nu; HF: 61 ± 33 nu). No differences among groups were found on non-linear HRV markers and endothelial reactivity indexes. Conclusions Individuals with T2DM showed impaired levels of cardiac autonomic markers when compared to individuals with SAH and PD, despite of having lower levels of BP and arterial stiffness.

Research paper thumbnail of Characterizing the interindividual postexercise hypotension response for two order groups of concurrent training in patients with morbid obesity

Frontiers in Physiology

Background: Postexercise hypotension (PEH) is a common physiological phenomenon occurring immedia... more Background: Postexercise hypotension (PEH) is a common physiological phenomenon occurring immediately after endurance training (ET), resistance training (RT), and ET plus RT, also termed concurrent training (CT); however, there is little knowledge about the interindividual and magnitude response of PEH in morbidly obese patients.Aim: The aims of this study were (1) to investigate the effect of CT order (ET + RT vs. RT + ET) on the blood pressure responses; 2) characterize these responses in responders and nonresponders, and 3) identify potential baseline outcomes for predicting blood pressure decreases as responders.Methods: A quasi-experimental study developed in sedentary morbidly obese men and women (age 43.6 ± 11.3 years; body mass index [BMI] ≥40 kg/m2) was assigned to a CT group of ET plus RT (ET + RT; n = 19; BMI 47.8 ± 16.7) or RT plus ET order group (RT + ET; n = 17; BMI 43.0 ± 8.0). Subjects of both groups received eight exercise sessions over four weeks. Primary outcomes ...

Research paper thumbnail of Contemporary review of exercise in heart transplant recipients

Transplantation Reviews, 2021

Heart transplantation (HTx) is a therapeutic option for a selected group of patients with end-sta... more Heart transplantation (HTx) is a therapeutic option for a selected group of patients with end-stage heart failure. Although secondary prevention including exercise therapy is recommended in the management of patients following HTx, little information is available on their metabolic and physiological consequences in HTx. Therefore, we aimed to conduct a contemporary review the effectiveness of exercise therapy on functional capacity, cardiovascular health and health-related quality of life for adult HTx patients. We searched the database MEDLINE for articles published between January 2015 and October 2020 and were able to include 6 studies involving 202 patients. Larger improvements in exercise capacity were seen after high-intensity interval training and in patients with evidence of cardiac reinnervation. Clinically relevant reductions were observed for daytime and 24 h ambulatory blood pressure after exercise training and following a single bout of aerobic exercise. Finally, limited data suggest that quality of life is higher in HTx patients following high-intensity training. In summary, the available evidence shows the potential for exercise as a vital treatment in patients following HTx. Yet, the scant data calls for more well-designed and adequately powered studies to support its effectiveness and to unravel optimal exercise characteristics, which would allow for more effective and person-tailored exercise prescription.

Research paper thumbnail of Residual Impact of Concurrent, Resistance, and High-Intensity Interval Training on Fasting Measures of Glucose Metabolism in Women With Insulin Resistance

Frontiers in Physiology, 2021

We sought to assess the residual effects (post 72-h training cessation) on fasting plasma glucose... more We sought to assess the residual effects (post 72-h training cessation) on fasting plasma glucose (FPG) and fasting insulin (FI) after 12-weeks of high-intensity interval training (HIIT), resistance training (RT), or concurrent training (CT) in women with insulin resistance (IR). We also aimed to determine the training-induced, post-training residual impact of CT. A total of adult 45 women (age 38.5±9.2years) were included in the final analysis and were assigned to a control (CG; n=13, BMI 28.3±3.6kg/m2), HIIT [n=14, BMI 28.6±3.6kg/m2, three sessions/wk., 80–100% of the maximum heart rate (HRmax)], RT [n=8, BMI 29.4±5.5kg/m2, two sessions/wk., 8–10 points of the modified Borg, corresponding to 20 to 50% range of one maximum repetition test (1RM)], or CT group (n=10, BMI 29.1±3.0kg/m2, three sessions/wk., 80–100% of HRmax, and 8–10 Borg, or 20 to 50% range of 1RM, to each HIIT and RT compounds), with the latter including both HIIT and RT regimens. Training interventions lasted 12-wee...

Research paper thumbnail of Short-term community-based exercise programs in low-income older women: Does exercise intensity and modality matters?

Experimental Gerontology, 2021

Our aim was to evaluate the effect of community-based exercise program (CBEP) intensity and modal... more Our aim was to evaluate the effect of community-based exercise program (CBEP) intensity and modality on anthropometric, hemodynamic, and functional capacity parameters in low-income older women. Forty insufficiently active older women (68.2 ± 7.9 years) were randomly assigned to perform 12 weeks of twice-weekly high-intensity interval training combined with resistance training (HIIT+RT/n = 12), moderate-intensity continuous training combined with resistance training (MICT+RT/n = 13), or resistance training alone (RT/n = 15). Anthropometric (body mass index and waist circumference), hemodynamic (blood pressure and heart rate), and functional capacity variables (flexibility, upper and lower limb muscle strength, and mobility) were assessed before and after training programs. Waist circumference reduced similarly after all CBEP (~3 to ~4 cm; P < 0.05). However, tendency toward reduction in diastolic blood pressure (~4 mm Hg; P = 0.073), and improvements in flexibility (14.5%, P = 0.011) and handgrip strength (15.8%; P = 0.02) were found only in HIIT+RT. Indeed, only RT was effective to improve five-time sit to stand (14.1%; P = 0.013). However, no significant difference between groups was found during follow-up in any variable. The results of present study suggest that low-income older women may improve anthropometric, hemodynamic and functional capacity variables by participating in twice-weekly short-term (i.e.: 12 weeks) CBEP. However, the CBEP-effects on hemodynamic and functional capacity appears to be affected by exercise intensity (only HIIT+RT tended toward improving diastolic BP) and modality (only RT improved significantly five-time sit to stand), respectively.

Research paper thumbnail of Hypotensive Effect of Heated Water-Based Exercise Persists After 12-Week Cessation of Training in Patients With Resistant Hypertension

Canadian Journal of Cardiology, 2018

Keeping blood pressure levels within the normal range is a clinical challenge in patients with hy... more Keeping blood pressure levels within the normal range is a clinical challenge in patients with hypertension. Studies have shown favorable benefits of regular exercise in controlling blood pressure. However, the hypotensive effects of exercise return to pretraining of BP levels within 3 months after cessation of exercise. This study demonstrated that the effects of heated waterbased exercise on blood pressure persisted after 3 months of cessation of exercise in patients with resistant hypertension.

Research paper thumbnail of High-Intensity Interval Training as a Tool for Counteracting Dyslipidemia in Women

International journal of sports medicine, Jan 21, 2018

Sedentary overweight or obese adult (age<60 years) women, allocated in type 2 diabetes mellitu... more Sedentary overweight or obese adult (age<60 years) women, allocated in type 2 diabetes mellitus (T2DM,=13), dyslipidemia alone (DYS,=12), dyslipidemia associated with hyperglycaemia (DYSHG, N=12), or healthy control (CON,=10) groups, had their lipid, glucose, blood pressure, endurance performance, and anthropometry variables assessed before and after 16 weeks of a thrice-weekly high-intensity interval training (HIIT) program. Triglycerides reduced significantly (<0.05) in all groups, and high-density lipoprotein increased (<0.01) in T2DM, DYS and DYSHG; however, low-density lipoprotein reduced (<0.05) only in DYSHG, and total cholesterol reduced (<0.01) only in DYS and DYSHG. Fasting glucose reduced (<0.05) significantly in T2DM, DYS and DYSHG, but with higher decreases in T2DM and DYSHG. Blood pressure, endurance performance and body composition improved (<0.05) in all groups. The HIIT program was effective for restoring lipid profile of DYS and DYSHG, and fast...

Research paper thumbnail of Low-Volume High-Intensity Interval Training as a Therapy for Type 2 Diabetes

International Journal of Sports Medicine, 2016

Our purpose was to investigate the effects of low-volume, high-intensity interval training (HIT) ... more Our purpose was to investigate the effects of low-volume, high-intensity interval training (HIT) on cardiometabolic risk and exercise capacity in women with type 2 diabetes mellitus (T2DM). Sedentary overweight/obese T2DM women (age=44.5±1.8 years; BMI=30.5±0.6 kg/m(2)) were randomly assigned to a tri-weekly running-based HIT program (n=13) or non-exercise control follow-up (CON; n=10). Glycemic control, lipid and blood pressure levels, endurance performance, and anthropometry were measured before and after the follow-up (16 weeks) in both groups. Medication intake was also assessed throughout the follow-up. Improvements (P<0.05) on fasting glucose (14.3±1.4%), HbA1c (12.8±1.1%), systolic blood pressure (3.7±0.5 mmHg), HDL-cholesterol (21.1±2.8%), triglycerides (17.7±2.8%), endurance performance (9.8±1.0%), body weight (2.2±0.3%), BMI (2.1±0.3%), waist circumference (4.0±0.5%) and subcutaneous fat (18.6±1.4%) were found after HIT intervention. Patients of HIT group also showed reductions in daily dosage of antihyperglycemic and antihypertensive medication during follow-up. No changes were found in any variable of CON group. The HIT-induced improvements occurred with a weekly time commitment 56-25% lower than the minimal recommended in current guidelines. These findings suggest that low-volume HIT may be a time-efficient intervention to treat T2DM women.

Research paper thumbnail of Efeitos agudos do exercício resistido, aeróbio contínuo e intervalado na pressão intraocular de indivíduos fisicamente ativos e normotensos

Although not yet explored, evidence suggests that physical activity promotes reduction and contri... more Although not yet explored, evidence suggests that physical activity promotes reduction and contributes in a Intraocular Pressure (IOP) control. The aim was to investigate the acute effect of different types of exercise on IOP. Fifteen volunteers were randomly assigned to 3 sessions of 30 minutes of exercise: resistance exercises: 3 sets of 8 repetitions at 80% 1RM; continuous aerobic exercise: 60% of Heart Rate Reserve (HRR); Aerobic Interval Exercise: intercalating 2min 50% 1min and 80% of HRR. IOP was measured before (M1) for 15min (M2) and immediately after the session (M3), and during recovery: 5min (R1) and 10 minutes (R2). As ANOVA statistical procedure was used. There were significant reductions of IOP during all exercise sessions (M2 and M3). After exercise, IOP remained low until 5min on all models, however, at 10 minutes was lower than in M1 only in interval workout

Research paper thumbnail of Atividade Física Como Ferramenta De Promoção De Saúde

Research paper thumbnail of Muscular and Functional Capacity in Subjects Under Treatment for Knee Osteoarthritis: Role of Physical Activity Status

Journal of Physical Activity and Health, 2019

Background: The purpose of this study was to assess the role of physical activity (PA) in muscula... more Background: The purpose of this study was to assess the role of physical activity (PA) in muscular and functional capacity in subjects under treatment for knee osteoarthritis submitted to an interdisciplinary educational program emphasizing the regular practice of PA and exercises. Methods: Subjects under treatment for primary knee osteoarthritis (N = 136; age = 66 [3]) were allocated in sedentary to sedentary (SED-SED, sedentary or insufficiently active at pre and post), active to sedentary (ACT-SED, active or very active at pre and sedentary or insufficiently active at post), sedentary to active (SED-ACT, sedentary or insufficiently active at pre and active or very active at post), and active to active (ACT-ACT, active or very active at pre and post) groups. Muscular capacity (isokinetic test), functional capacity (timed up and down stairs test, timed up and go test, and 5 times sit to stand test), and daily living PA (International PA Questionnaire short version) were assessed before and after (12 mo) the follow-up. Results: There were improvements in performance (P < .05) in the time to up and down stairs: 37% in SED-ACT and 27.5% in ACT-ACT; timed up and go test: 33.5% in SED-ACT, 19% in ACT-SED, and 40% in ACT-ACT; 5 times sit to stand test: 39% in SED-ACT and 51% in ACT-ACT groups after 12 months of follow-up. Conclusions: The present results suggest that high levels of daily living PA may have an important role in the prevention/management of knee osteoarthritis.

Research paper thumbnail of Resistance Training as a Tool for Preventing and Treating Musculoskeletal Disorders

Sports Medicine, 2016

The aging process is characterized by several physiological, morphological, and psychological alt... more The aging process is characterized by several physiological, morphological, and psychological alterations that result in a decreased functional and health status throughout the life span. Among these alterations, the loss of muscle mass and strength (sarcopenia) is receiving increased attention because of its association with innumerous age-related disorders, including (but not limited to) osteoporosis, osteoarthritis, low back pain, risk of fall, and disability. Regular participation in resistance training programs can minimize the musculoskeletal alterations that occur during aging, and may contribute to the health and well-being of the older population. Compelling evidence suggest that regular practice of resistance exercise may prevent and control the development of several musculoskeletal chronic diseases. Moreover, resistance training may also improve physical fitness, function, and independence in older people with musculoskeletal disorders, which may result in improved quality of the years lived. In summary, regular participation in resistance training programs plays an important role in aging and may be a preventive and therapeutic tool for several musculoskeletal disorders.