Tandzhu Mehmedov | Printnem - Academia.edu (original) (raw)

Papers by Tandzhu Mehmedov

In ovo models (avian embryos) are a novel alternative to laboratory animals used in the experimen... more In ovo models (avian embryos) are a novel alternative to laboratory animals used in the experimental cancer research. In the present study, the preneoplastic liver lesions induced by N-nitrosodiethylamine in guinea fowls were examined by histopatological methods. The alterations of some hematological and biochemical parameters were examined in guinea fowls hatched from carcinogen-inoculated eggs. Histopathology confirmed the presence of basophilic and eosinophilic foci of altered hepatocytes, strongly resembling the morphology of the preneoplastic lesions previously found in other avian species and laboratory rodents treated with the same carcinogen, as well as in humans with hepatocellular carcinomas. In addition to the focal hepatic lesions, pronounced hyperplasia of cholangiocytes and spongiosis hepatis were also detected in treated guinea fowls. The established alterations of hematological and biochemical parameters included thrombocytopenia and an increase of the levels of majo...

One approach of genetic selection is using genetic markers for the identification of breeding tra... more One approach of genetic selection is using genetic markers for the identification of breeding traits with economic importance. A gene which is already used as a marker gene is MSTN. It is responsible for the synthesis of the myostatin protein that regulates muscle growth. Mutations leading to loss of function (loss of-functional mutations) in the myostatin gene (MSTN) are associated with increased skeletal muscle mass ("doublemuscling"), which is connected with poor meat quality characteristics. In some cases it was found abnormal adipogenesis consisting in a reduced liptin secretion, changes in the structure of ligament, reproductive problems. Introduction Improving the quantitative and qualitative characteristics of the carcass is one of the main tasks of modern genetics and selection. With the increase in the share of intellectual work, the requirements of consumers turned to search for lean meat with low fat content. Modern science has different methods to meet the mar...

The survey covers 140 clinically healthy sheep from two indigenous sheep breeds -Karakachan (KK)a... more The survey covers 140 clinically healthy sheep from two indigenous sheep breeds -Karakachan (KK)and Copper-Red Shumen (CRS) over one year old. Blood samples are taken from v. jugularis, and using a semi-automatic biochemical analyzer were determined in serum levels of blood sugar, total serum protein and albumin, creatinine, urea, calcium, inorganic phosphorus and magnesium. The results obtained indicated that the levels of total protein (75.81±7.03 for KK and 72.19±5.64 for CRS), albumin (44.85±6.43 for KK and 42.09±4.06 for CRS), creatinine (183.35±291.77 for KK and 128.30±45.70 for CRS) and urea (9.30±3.90 for KK and 11.10±5.76 for CRS) in Karakachan breed are poorly higher than those of the Copper -Red Shumen. The values of blood sugar (2.89±0.49 for KK and 2.49±0.57 for CRS), calcium (2.30±0.41 for KK and 2.22±0.33 for CRS), inorganic phosphorus (1.94±0.64 for KK and 1.94±0.44 for CRS) and magnesium (1.23±0.29 for KK and 1.14±0.20 for CRS) showed no breed differences. The significant differences between the two breeds were obtained only in value of both creatinine and blood sugar.

GENOVA, K. and T. MEHMEDOV, 2016. Study of performance on natural resistance in pheasants, infect... more GENOVA, K. and T. MEHMEDOV, 2016. Study of performance on natural resistance in pheasants, infected with pathogenic strain of E.coli and treated with Enterococcus Faecium M74. Bulg. J. Agric. Sci., 22: 140–143 Probiotics are live micro-organisms that bring benefits to consumer health. It is well known that they are used for prevention of bacterial diseases in poultry, as well as to potent the growth performance and immune response of poultry. The present work was carried out to evaluate the effectiveness of probiotic Laktiferm Basic 300® on natural resistance in pheasants, infected with pathogenic strain of E.coli. Pheasants were inoculated intra ingluvial with enteropathogenic strain of E.coli O 103 in an amount of 108 cfu/ml on the 3rd day and divided into four equal groups: Group (1) served as a positive control group, received colistin sulfate. Group (2) was negative control. Group (3) was fed with the probiotic while group (4) was fed with nutritional antibiotic Pharmastim 8%® ...

Some haematological and biochemical parameters in turkeys, hatched from embryonated eggs inoculat... more Some haematological and biochemical parameters in turkeys, hatched from embryonated eggs inoculated with the proven hepatocarcinogen N-nitrosodiethylamine were studied. Histopathology confirmed the presence of clear-cell and basophilic foci of altered hepatocytes and hyperplasia of cholangiocytes. The application of the chemical carcinogen affected both haematological and biochemical parameters. The established conditions such as thrombocytopenia and increased levels of the major liver enzymes were associated with the process of malignancy. In addition, leukogram abnormalities (leukocytosis, lymphocytosis and neutropenia) as well as hypoproteinaemia, hypoalbuminaemia and hypoglycemia were also observed.

Some haematological and biochemical parameters in turkeys, hatched from embryonated eggs inoculat... more Some haematological and biochemical parameters in turkeys, hatched from embryonated eggs inoculated with the proven hepatocarcinogen N-nitrosodiethylamine were studied. Histopathology confirmed the presence of clear-cell and basophilic foci of altered hepatocytes and hyperplasia of cholangiocytes. The application of the chemical carcinogen affected both haematological and biochemical parameters. The established conditions such as thrombocytopenia and increased levels of the major liver enzymes were associated with the process of malignancy. In addition, leukogram abnormalities (leukocytosis, lymphocytosis and neutropenia) as well as hypoproteinaemia, hypoalbuminaemia and hypoglycemia were also observed.

In ovo models (avian embryos) are a novel alternative to laboratory animals used in the experimen... more In ovo models (avian embryos) are a novel alternative to laboratory animals used in the experimental cancer research. In the present study, the preneoplastic liver lesions induced by N-nitrosodiethylamine in guinea fowls were examined by histopatological methods. The alterations of some hematological and biochemical parameters were examined in guinea fowls hatched from carcinogen-inoculated eggs. Histopathology confirmed the presence of basophilic and eosinophilic foci of altered hepatocytes, strongly resembling the morphology of the preneoplastic lesions previously found in other avian species and laboratory rodents treated with the same carcinogen, as well as in humans with hepatocellular carcinomas. In addition to the focal hepatic lesions, pronounced hyperplasia of cholangiocytes and spongiosis hepatis were also detected in treated guinea fowls. The established alterations of hematological and biochemical parameters included thrombocytopenia and an increase of the levels of majo...

The aim of the present research is to study the content of lead in feathers and bone samples in e... more The aim of the present research is to study the content of lead in feathers and bone samples in eight carcasses of Griffon Vultures (Gyps fulvus, Habitz 1870) from a region in southwestern Bulgaria. In order to exclude surface lead contamination, the feather samples were preliminary examined by X-ray fluorescent spectroscopy. The samples of lead concentration in feathers and bones were analyzed by the methods of ICP-MS Spectrometry. The results displayed residues of lead in the feathers and bones only in some individuals.

Toxic and carcinogenic effects induced in ovo by N-nitrosodimethylamine and N-nitrosodiethylamine... more Toxic and carcinogenic effects induced in ovo by N-nitrosodimethylamine and N-nitrosodiethylamine in Japanese quail embryos were studied by histopathological methods. The obtained results indicate that both compounds induce preneoplastic hepatic alterations. The spectrum of macroscopic and microscopic lesions identified in carcinogen-treated embryos has been presented. The significance of avian embryos as an inexpensive and reliable model system for studies on hepatocarcinogenesis has been briefly discussed.

In ovo models (avian embryos) are a novel alternative to laboratory animals used in the experimen... more In ovo models (avian embryos) are a novel alternative to laboratory animals used in the experimental cancer research. In the present study, the preneoplastic liver lesions induced by N-nitrosodiethylamine in guinea fowls were examined by histopatological methods. The alterations of some hematological and biochemical parameters were examined in guinea fowls hatched from carcinogen-inoculated eggs. Histopathology confirmed the presence of basophilic and eosinophilic foci of altered hepatocytes, strongly resembling the morphology of the preneoplastic lesions previously found in other avian species and laboratory rodents treated with the same carcinogen, as well as in humans with hepatocellular carcinomas. In addition to the focal hepatic lesions, pronounced hyperplasia of cholangiocytes and spongiosis hepatis were also detected in treated guinea fowls. The established alterations of hematological and biochemical parameters included thrombocytopenia and an increase of the levels of majo...

In ovo models (avian embryos) are a novel alternative to laboratory animals used in the experimen... more In ovo models (avian embryos) are a novel alternative to laboratory animals used in the experimental cancer research. In the present study, the preneoplastic liver lesions induced by N-nitrosodiethylamine in guinea fowls were examined by histopatological methods. The alterations of some hematological and biochemical parameters were examined in guinea fowls hatched from carcinogen-inoculated eggs. Histopathology confirmed the presence of basophilic and eosinophilic foci of altered hepatocytes, strongly resembling the morphology of the preneoplastic lesions previously found in other avian species and laboratory rodents treated with the same carcinogen, as well as in humans with hepatocellular carcinomas. In addition to the focal hepatic lesions, pronounced hyperplasia of cholangiocytes and spongiosis hepatis were also detected in treated guinea fowls. The established alterations of hematological and biochemical parameters included thrombocytopenia and an increase of the levels of majo...

In ovo models (avian embryos) are a novel alternative to laboratory animals used in the experimen... more In ovo models (avian embryos) are a novel alternative to laboratory animals used in the experimental cancer research. In the present study, the preneoplastic liver lesions induced by N-nitrosodiethylamine in guinea fowls were examined by histopatological methods. The alterations of some hematological and biochemical parameters were examined in guinea fowls hatched from carcinogen-inoculated eggs. Histopathology confirmed the presence of basophilic and eosinophilic foci of altered hepatocytes, strongly resembling the morphology of the preneoplastic lesions previously found in other avian species and laboratory rodents treated with the same carcinogen, as well as in humans with hepatocellular carcinomas. In addition to the focal hepatic lesions, pronounced hyperplasia of cholangiocytes and spongiosis hepatis were also detected in treated guinea fowls. The established alterations of hematological and biochemical parameters included thrombocytopenia and an increase of the levels of majo...

The paper presents for determination of lead in the liver, kidney, breast muscles and humerus of ... more The paper presents for determination of lead in the liver, kidney, breast muscles and humerus of mallards (Anas platyrhynchos, L), treated orally with lead shot pellets. The results obtained show significant elevation tissue concentrations of lead in relation to the control values. The highest values were established in the hu-merus, followed by the kidneys, liver and breast muscles.

The paper presents for determination of lead in the liver, kidney, breast muscles and humerus of ... more The paper presents for determination of lead in the liver, kidney, breast muscles and humerus of mallards (Anas platyrhynchos, L), treated orally with lead shot pellets. The results obtained show significant elevation tissue concentrations of lead in relation to the control values. The highest values were established in the hu-merus, followed by the kidneys, liver and breast muscles.

One approach of genetic selection is using genetic markers for the identification of breeding tra... more One approach of genetic selection is using genetic markers for the identification of breeding traits with economic importance. A gene which is already used as a marker gene is MSTN. It is responsible for the synthesis of the myostatin protein that regulates muscle growth. Mutations leading to loss of function (loss of-functional mutations) in the myostatin gene (MSTN) are associated with increased skeletal muscle mass ("doublemuscling"), which is connected with poor meat quality characteristics. In some cases it was found abnormal adipogenesis consisting in a reduced liptin secretion, changes in the structure of ligament, reproductive problems. Introduction Improving the quantitative and qualitative characteristics of the carcass is one of the main tasks of modern genetics and selection. With the increase in the share of intellectual work, the requirements of consumers turned to search for lean meat with low fat content. Modern science has different methods to meet the mar...

A study of fallow deer reared in enclosures at the "Eledjik" hunting farm and free-rang... more A study of fallow deer reared in enclosures at the "Eledjik" hunting farm and free-range at the "Studen kladenets"hunting farm was carried out. Both habitats are at different altitudes and the natural food base differs in terms of grassland, botanical composition and nutritional value. The study included an examination of blood samples from fallow deer's from both habitats. The following biochemical indicators of the blood were examined: albumin, protein, calcium, phosphorus and magnesium. In order to determine the digestibility of the nutrients, samples were taken from the natural meadows and pastures found in the habitats as well as faecal samples tested for: moisture, protein, fat, raw ash and (mineral) and non-nitrogenous extracts. The results show differences between the studied indicators in the two habitats, which are probably due to the differences in the botanical composition of the grass in the natural habitats, as well as to the different compositi...

The study included 140 clinically healthy animals from two indigenous sheep breeds - Karakachania... more The study included 140 clinically healthy animals from two indigenous sheep breeds - Karakachanian and Copper Red Shumen over one year old. The levels of serum ASAT, ALAT, Alkaline Phosphatase, KC (Creatine Kinase) and LDH (Lactate Dehydrogenase) were determined. The obtained results show that the values of ASAT and ALAT between the breeds are no significant differences, due to which these serum enzymes have smaller breed informational value. Levels of Alkaline Phosphatase, KC and LDH in Copper Red Shumen in varying degrees higher than the Karakachanian breed.

Two licensed industrial pig farms from different regions of Bulgaria, with laboratory confirmed e... more Two licensed industrial pig farms from different regions of Bulgaria, with laboratory confirmed enzootic pneumonia had clinical and hematological studies. In the study farms the disease occurs in acute and subclinical form. According to the severity of clinical signs studied pigs were grouped into treatment groups. Of all pigs in the group were taken into sterile blood samples for paraclinical study. The results showed changes in red blood cell (eritropeniya, hemoglobinopeniya and decrease in hematocrit) in the white blood cell count (leukopenia, lymphopenia and eozinofilopeniya) and biochemical parameters (hypoproteinaemia, hypoalbuminaemia and hyperglycaemia) of experimental pigs.

Scientific Works. Series C. Veterinary Medicine, 2014

Two licensed industrial pig farms from different regions of Bulgaria, with laboratory confirmed e... more Two licensed industrial pig farms from different regions of Bulgaria, with laboratory confirmed enzootic pneumonia had clinical and hematological studies. In the study farms the disease occurs in acute and subclinical form. According to the severity of clinical signs studied pigs were grouped into treatment groups. Of all pigs in the group were taken into sterile blood samples for paraclinical study. The results showed changes in red blood cell (eritropeniya, hemoglobinopeniya and decrease in hematocrit) in the white blood cell count (leukopenia, lymphopenia and eozinofilopeniya) and biochemical parameters (hypoproteinaemia, hypoalbuminaemia and hyperglycaemia) of experimental pigs.

In ovo models (avian embryos) are a novel alternative to laboratory animals used in the experimen... more In ovo models (avian embryos) are a novel alternative to laboratory animals used in the experimental cancer research. In the present study, the preneoplastic liver lesions induced by N-nitrosodiethylamine in guinea fowls were examined by histopatological methods. The alterations of some hematological and biochemical parameters were examined in guinea fowls hatched from carcinogen-inoculated eggs. Histopathology confirmed the presence of basophilic and eosinophilic foci of altered hepatocytes, strongly resembling the morphology of the preneoplastic lesions previously found in other avian species and laboratory rodents treated with the same carcinogen, as well as in humans with hepatocellular carcinomas. In addition to the focal hepatic lesions, pronounced hyperplasia of cholangiocytes and spongiosis hepatis were also detected in treated guinea fowls. The established alterations of hematological and biochemical parameters included thrombocytopenia and an increase of the levels of majo...

One approach of genetic selection is using genetic markers for the identification of breeding tra... more One approach of genetic selection is using genetic markers for the identification of breeding traits with economic importance. A gene which is already used as a marker gene is MSTN. It is responsible for the synthesis of the myostatin protein that regulates muscle growth. Mutations leading to loss of function (loss of-functional mutations) in the myostatin gene (MSTN) are associated with increased skeletal muscle mass ("doublemuscling"), which is connected with poor meat quality characteristics. In some cases it was found abnormal adipogenesis consisting in a reduced liptin secretion, changes in the structure of ligament, reproductive problems. Introduction Improving the quantitative and qualitative characteristics of the carcass is one of the main tasks of modern genetics and selection. With the increase in the share of intellectual work, the requirements of consumers turned to search for lean meat with low fat content. Modern science has different methods to meet the mar...

The survey covers 140 clinically healthy sheep from two indigenous sheep breeds -Karakachan (KK)a... more The survey covers 140 clinically healthy sheep from two indigenous sheep breeds -Karakachan (KK)and Copper-Red Shumen (CRS) over one year old. Blood samples are taken from v. jugularis, and using a semi-automatic biochemical analyzer were determined in serum levels of blood sugar, total serum protein and albumin, creatinine, urea, calcium, inorganic phosphorus and magnesium. The results obtained indicated that the levels of total protein (75.81±7.03 for KK and 72.19±5.64 for CRS), albumin (44.85±6.43 for KK and 42.09±4.06 for CRS), creatinine (183.35±291.77 for KK and 128.30±45.70 for CRS) and urea (9.30±3.90 for KK and 11.10±5.76 for CRS) in Karakachan breed are poorly higher than those of the Copper -Red Shumen. The values of blood sugar (2.89±0.49 for KK and 2.49±0.57 for CRS), calcium (2.30±0.41 for KK and 2.22±0.33 for CRS), inorganic phosphorus (1.94±0.64 for KK and 1.94±0.44 for CRS) and magnesium (1.23±0.29 for KK and 1.14±0.20 for CRS) showed no breed differences. The significant differences between the two breeds were obtained only in value of both creatinine and blood sugar.

GENOVA, K. and T. MEHMEDOV, 2016. Study of performance on natural resistance in pheasants, infect... more GENOVA, K. and T. MEHMEDOV, 2016. Study of performance on natural resistance in pheasants, infected with pathogenic strain of E.coli and treated with Enterococcus Faecium M74. Bulg. J. Agric. Sci., 22: 140–143 Probiotics are live micro-organisms that bring benefits to consumer health. It is well known that they are used for prevention of bacterial diseases in poultry, as well as to potent the growth performance and immune response of poultry. The present work was carried out to evaluate the effectiveness of probiotic Laktiferm Basic 300® on natural resistance in pheasants, infected with pathogenic strain of E.coli. Pheasants were inoculated intra ingluvial with enteropathogenic strain of E.coli O 103 in an amount of 108 cfu/ml on the 3rd day and divided into four equal groups: Group (1) served as a positive control group, received colistin sulfate. Group (2) was negative control. Group (3) was fed with the probiotic while group (4) was fed with nutritional antibiotic Pharmastim 8%® ...

Some haematological and biochemical parameters in turkeys, hatched from embryonated eggs inoculat... more Some haematological and biochemical parameters in turkeys, hatched from embryonated eggs inoculated with the proven hepatocarcinogen N-nitrosodiethylamine were studied. Histopathology confirmed the presence of clear-cell and basophilic foci of altered hepatocytes and hyperplasia of cholangiocytes. The application of the chemical carcinogen affected both haematological and biochemical parameters. The established conditions such as thrombocytopenia and increased levels of the major liver enzymes were associated with the process of malignancy. In addition, leukogram abnormalities (leukocytosis, lymphocytosis and neutropenia) as well as hypoproteinaemia, hypoalbuminaemia and hypoglycemia were also observed.

Some haematological and biochemical parameters in turkeys, hatched from embryonated eggs inoculat... more Some haematological and biochemical parameters in turkeys, hatched from embryonated eggs inoculated with the proven hepatocarcinogen N-nitrosodiethylamine were studied. Histopathology confirmed the presence of clear-cell and basophilic foci of altered hepatocytes and hyperplasia of cholangiocytes. The application of the chemical carcinogen affected both haematological and biochemical parameters. The established conditions such as thrombocytopenia and increased levels of the major liver enzymes were associated with the process of malignancy. In addition, leukogram abnormalities (leukocytosis, lymphocytosis and neutropenia) as well as hypoproteinaemia, hypoalbuminaemia and hypoglycemia were also observed.

In ovo models (avian embryos) are a novel alternative to laboratory animals used in the experimen... more In ovo models (avian embryos) are a novel alternative to laboratory animals used in the experimental cancer research. In the present study, the preneoplastic liver lesions induced by N-nitrosodiethylamine in guinea fowls were examined by histopatological methods. The alterations of some hematological and biochemical parameters were examined in guinea fowls hatched from carcinogen-inoculated eggs. Histopathology confirmed the presence of basophilic and eosinophilic foci of altered hepatocytes, strongly resembling the morphology of the preneoplastic lesions previously found in other avian species and laboratory rodents treated with the same carcinogen, as well as in humans with hepatocellular carcinomas. In addition to the focal hepatic lesions, pronounced hyperplasia of cholangiocytes and spongiosis hepatis were also detected in treated guinea fowls. The established alterations of hematological and biochemical parameters included thrombocytopenia and an increase of the levels of majo...

The aim of the present research is to study the content of lead in feathers and bone samples in e... more The aim of the present research is to study the content of lead in feathers and bone samples in eight carcasses of Griffon Vultures (Gyps fulvus, Habitz 1870) from a region in southwestern Bulgaria. In order to exclude surface lead contamination, the feather samples were preliminary examined by X-ray fluorescent spectroscopy. The samples of lead concentration in feathers and bones were analyzed by the methods of ICP-MS Spectrometry. The results displayed residues of lead in the feathers and bones only in some individuals.

Toxic and carcinogenic effects induced in ovo by N-nitrosodimethylamine and N-nitrosodiethylamine... more Toxic and carcinogenic effects induced in ovo by N-nitrosodimethylamine and N-nitrosodiethylamine in Japanese quail embryos were studied by histopathological methods. The obtained results indicate that both compounds induce preneoplastic hepatic alterations. The spectrum of macroscopic and microscopic lesions identified in carcinogen-treated embryos has been presented. The significance of avian embryos as an inexpensive and reliable model system for studies on hepatocarcinogenesis has been briefly discussed.

In ovo models (avian embryos) are a novel alternative to laboratory animals used in the experimen... more In ovo models (avian embryos) are a novel alternative to laboratory animals used in the experimental cancer research. In the present study, the preneoplastic liver lesions induced by N-nitrosodiethylamine in guinea fowls were examined by histopatological methods. The alterations of some hematological and biochemical parameters were examined in guinea fowls hatched from carcinogen-inoculated eggs. Histopathology confirmed the presence of basophilic and eosinophilic foci of altered hepatocytes, strongly resembling the morphology of the preneoplastic lesions previously found in other avian species and laboratory rodents treated with the same carcinogen, as well as in humans with hepatocellular carcinomas. In addition to the focal hepatic lesions, pronounced hyperplasia of cholangiocytes and spongiosis hepatis were also detected in treated guinea fowls. The established alterations of hematological and biochemical parameters included thrombocytopenia and an increase of the levels of majo...

In ovo models (avian embryos) are a novel alternative to laboratory animals used in the experimen... more In ovo models (avian embryos) are a novel alternative to laboratory animals used in the experimental cancer research. In the present study, the preneoplastic liver lesions induced by N-nitrosodiethylamine in guinea fowls were examined by histopatological methods. The alterations of some hematological and biochemical parameters were examined in guinea fowls hatched from carcinogen-inoculated eggs. Histopathology confirmed the presence of basophilic and eosinophilic foci of altered hepatocytes, strongly resembling the morphology of the preneoplastic lesions previously found in other avian species and laboratory rodents treated with the same carcinogen, as well as in humans with hepatocellular carcinomas. In addition to the focal hepatic lesions, pronounced hyperplasia of cholangiocytes and spongiosis hepatis were also detected in treated guinea fowls. The established alterations of hematological and biochemical parameters included thrombocytopenia and an increase of the levels of majo...

In ovo models (avian embryos) are a novel alternative to laboratory animals used in the experimen... more In ovo models (avian embryos) are a novel alternative to laboratory animals used in the experimental cancer research. In the present study, the preneoplastic liver lesions induced by N-nitrosodiethylamine in guinea fowls were examined by histopatological methods. The alterations of some hematological and biochemical parameters were examined in guinea fowls hatched from carcinogen-inoculated eggs. Histopathology confirmed the presence of basophilic and eosinophilic foci of altered hepatocytes, strongly resembling the morphology of the preneoplastic lesions previously found in other avian species and laboratory rodents treated with the same carcinogen, as well as in humans with hepatocellular carcinomas. In addition to the focal hepatic lesions, pronounced hyperplasia of cholangiocytes and spongiosis hepatis were also detected in treated guinea fowls. The established alterations of hematological and biochemical parameters included thrombocytopenia and an increase of the levels of majo...

The paper presents for determination of lead in the liver, kidney, breast muscles and humerus of ... more The paper presents for determination of lead in the liver, kidney, breast muscles and humerus of mallards (Anas platyrhynchos, L), treated orally with lead shot pellets. The results obtained show significant elevation tissue concentrations of lead in relation to the control values. The highest values were established in the hu-merus, followed by the kidneys, liver and breast muscles.

The paper presents for determination of lead in the liver, kidney, breast muscles and humerus of ... more The paper presents for determination of lead in the liver, kidney, breast muscles and humerus of mallards (Anas platyrhynchos, L), treated orally with lead shot pellets. The results obtained show significant elevation tissue concentrations of lead in relation to the control values. The highest values were established in the hu-merus, followed by the kidneys, liver and breast muscles.

One approach of genetic selection is using genetic markers for the identification of breeding tra... more One approach of genetic selection is using genetic markers for the identification of breeding traits with economic importance. A gene which is already used as a marker gene is MSTN. It is responsible for the synthesis of the myostatin protein that regulates muscle growth. Mutations leading to loss of function (loss of-functional mutations) in the myostatin gene (MSTN) are associated with increased skeletal muscle mass ("doublemuscling"), which is connected with poor meat quality characteristics. In some cases it was found abnormal adipogenesis consisting in a reduced liptin secretion, changes in the structure of ligament, reproductive problems. Introduction Improving the quantitative and qualitative characteristics of the carcass is one of the main tasks of modern genetics and selection. With the increase in the share of intellectual work, the requirements of consumers turned to search for lean meat with low fat content. Modern science has different methods to meet the mar...

A study of fallow deer reared in enclosures at the "Eledjik" hunting farm and free-rang... more A study of fallow deer reared in enclosures at the "Eledjik" hunting farm and free-range at the "Studen kladenets"hunting farm was carried out. Both habitats are at different altitudes and the natural food base differs in terms of grassland, botanical composition and nutritional value. The study included an examination of blood samples from fallow deer's from both habitats. The following biochemical indicators of the blood were examined: albumin, protein, calcium, phosphorus and magnesium. In order to determine the digestibility of the nutrients, samples were taken from the natural meadows and pastures found in the habitats as well as faecal samples tested for: moisture, protein, fat, raw ash and (mineral) and non-nitrogenous extracts. The results show differences between the studied indicators in the two habitats, which are probably due to the differences in the botanical composition of the grass in the natural habitats, as well as to the different compositi...

The study included 140 clinically healthy animals from two indigenous sheep breeds - Karakachania... more The study included 140 clinically healthy animals from two indigenous sheep breeds - Karakachanian and Copper Red Shumen over one year old. The levels of serum ASAT, ALAT, Alkaline Phosphatase, KC (Creatine Kinase) and LDH (Lactate Dehydrogenase) were determined. The obtained results show that the values of ASAT and ALAT between the breeds are no significant differences, due to which these serum enzymes have smaller breed informational value. Levels of Alkaline Phosphatase, KC and LDH in Copper Red Shumen in varying degrees higher than the Karakachanian breed.

Two licensed industrial pig farms from different regions of Bulgaria, with laboratory confirmed e... more Two licensed industrial pig farms from different regions of Bulgaria, with laboratory confirmed enzootic pneumonia had clinical and hematological studies. In the study farms the disease occurs in acute and subclinical form. According to the severity of clinical signs studied pigs were grouped into treatment groups. Of all pigs in the group were taken into sterile blood samples for paraclinical study. The results showed changes in red blood cell (eritropeniya, hemoglobinopeniya and decrease in hematocrit) in the white blood cell count (leukopenia, lymphopenia and eozinofilopeniya) and biochemical parameters (hypoproteinaemia, hypoalbuminaemia and hyperglycaemia) of experimental pigs.

Scientific Works. Series C. Veterinary Medicine, 2014

Two licensed industrial pig farms from different regions of Bulgaria, with laboratory confirmed e... more Two licensed industrial pig farms from different regions of Bulgaria, with laboratory confirmed enzootic pneumonia had clinical and hematological studies. In the study farms the disease occurs in acute and subclinical form. According to the severity of clinical signs studied pigs were grouped into treatment groups. Of all pigs in the group were taken into sterile blood samples for paraclinical study. The results showed changes in red blood cell (eritropeniya, hemoglobinopeniya and decrease in hematocrit) in the white blood cell count (leukopenia, lymphopenia and eozinofilopeniya) and biochemical parameters (hypoproteinaemia, hypoalbuminaemia and hyperglycaemia) of experimental pigs.