Parveen Gulati | Maulana Azad Medical College (original) (raw)

Papers by Parveen Gulati

The Journal of the Association of Physicians of India, 1990

A patient with Burkitt's lymphoma who had nervous system involvement at multiple levels is pr... more A patient with Burkitt's lymphoma who had nervous system involvement at multiple levels is presented because of the rarity of this condition in India. A high index of suspicion and a rapidly evolving multiple neuraxial involvement led to the diagnosis.

A 13-year-old boy presented with acute stroke leading to right-sided hemiparesis. A contrast CT s... more A 13-year-old boy presented with acute stroke leading to right-sided hemiparesis. A contrast CT scan of the brain showed a hemorrhagic infarct in the left basal ganglia region with surrounding edema. Echocardiography showed a hydatid cyst in the right atrial chamber extending ...

The Journal of Obstetrics and Gynecology of India, 2011

Objectives: To compare the bone mineral density (BMD) and its variables in premenopausal and post... more Objectives: To compare the bone mineral density (BMD) and its variables in premenopausal and postmenopausal women. Methods: In this cross sectional study, 62 premenopausal and 62 postmenopausal apparently healthy women were evaluated by a questionnaire. The dietary intake of calcium was evaluated by 24 hours recall method and using table for proximate principle of common Indian food by Indian Council of Medical Research (ICMR). BMD at lumbar spine, femoral neck and Ward's triangle were measured by dual energy X-ray absorptiometry (DXA). A correlation between BMD and various variables were calculated for each of the two groups.Results: The mean age of premenopausal and postmenopausal women was 32.46+7.8 and 51.74+7.1 years respectively. The body mass index (BMI), height and weight were comparable in both the groups. The daily intake of calcium was significantly higher in premenopausal women (p<0.01). Approximately, 17% of the postmenopausal women and 9.6% of the premenopausal women were having osteoporosis; 28.56% of the postmenopausal women and 43.54% of the premenopausal women were having osteopenia at the lumbar spine. The BMD at lumber spine was found to be statistically significantly higher in premenopausal women than that in postmenopausal women (p=0.03). BMD at lumbar spine, femoral neck and Ward's triangle were positively correlated with height, weight, BMI in premenopausal as well in postmenopausal women. Conclusion: A significant number of women had osteopenia during premenopausal period and osteoporosis in postmenopausal phase. By increasing awareness towards bone health in second and third decade, morbidity of osteoporosis can be reduced.

Indian Journal of Radiology and Imaging, 2005

Journal of Pediatric Gastroenterology and Nutrition, 1991

Indian pediatrics, 1991

Forty infants with proven pyogenic meningitis were evaluated by real time cranial sonography. A s... more Forty infants with proven pyogenic meningitis were evaluated by real time cranial sonography. A spectrum of sonographic abnormalities was observed which included echogenic sulci, focal or diffuse increase in parenchymal echoes, ventriculitis, ventriculomegaly with or without aqueductal block, subdural collection, parenchymal infarcts, abscess and subdural empyema. There were two infants with normal sonogram while encephalomalacia was seen in another two patients. An excellent correlation was observed between clinical profile, cerebrospinal fluid biochemistry and sonographic findings.

Indian pediatrics, 1991

Six term newborns, presenting with seizures, in whom cranial sonogram showed isolated periventric... more Six term newborns, presenting with seizures, in whom cranial sonogram showed isolated periventricular hemorrhage (SEH) are described. Age of onset of seizures ranged from day one of birth to day twenty-one. Seizures appeared spontaneously in previously healthy newborns in three cases. All but one survived, and three have near normal development. Isolation of hemorrhage to the periventricular area suggests germinal matrix to be the source of hemorrhage in these cases. These cases also emphasize the need to consider diagnosis of IVH in term-newborns presenting with seizures.

Neurology India, 2003

Postgraduate Medical Journal, 1991

A case of neurocysticercosis in an 11 year old female manifesting only as myoclonic seizures is r... more A case of neurocysticercosis in an 11 year old female manifesting only as myoclonic seizures is reported. The diagnosis was based upon ELISA test, computed tomography, and biopsy of a subcutaneous nodule. The patient responded to anticysticerci drug treatment. Neurocysticercosis has not to our knowledge been previously reported to have presented with myoclonus.

Gut, 1990

This study was carried out to assess pancreatic duct abnormalities in gall stone disease. Endosco... more This study was carried out to assess pancreatic duct abnormalities in gall stone disease. Endoscopic retrograde cholangiopancreatograms of 50 patients with gall stone disease were analysed and the results compared with those obtained in 33 patients investigated for cholestatic jaundice who were found to have a normal biliary tree (control group). Abnormal pancreatograms were obtained in 24 (48%) patients with gall stone disease and in only two (6%) in the control group; the differences were statistically significant (x2=14X3; p<0 001). The patients in the control group showed mild abnormalities as did those in the gail stone group. The frequency of various abnormalities were: mild 16 (32%), moderate five (10%), and severe three (6%). Pancreatic duct abnormalities were more severe and occurred more frequently in patients with gail stones who had stones in the biliary tree than in patients with a normal biliary tree (postcholecystectomy patients, 55% v 25%) but the difference between the two groups just failed to be significant (x2=3 34). In conclusion, nearly half of all patients with gall stone disease have pancreatic duct abnormalities and in 16% these were severe enough to be labelled as chronic pancreatitis.

Journal of the Indian Medical Association, 1999

The aim of the study was to assess the efficacy, tolerability and chondroprotection afforded by n... more The aim of the study was to assess the efficacy, tolerability and chondroprotection afforded by nimesulide, a selective cyclooxygenase-2 inhibitor and piroxicam in a randomised, double blind, controlled clinical trial in 90 patients suffering from osteoarthritis of the knee joint. A significant improvement in the osteoarthritis severity index at 2 weeks (p < 0.01) and an improvement in physicians assessment of global arthritic condition at 4 weeks (p < 0.01) was seen with both the treatments. A significant decrease in articular index of joint tenderness (p < 0.05) at 8 weeks and in self assessment of handicap at 4 weeks (p < 0.05), in comparison to baseline, was observed only in patients receiving nimesulide. Rescue therapy was required by a greater percentage of patients being administered piroxicam. Functional capacity improved in 64% of the patients on nimesulide and 74.5% of the patients receiving piroxicam. Adverse effects were observed in 6 patients on nimesulide a...

Spine, 1999

Study Design. A retrospective cohort study of tractordriving farmers (study group) and non-tracto... more Study Design. A retrospective cohort study of tractordriving farmers (study group) and non-tractor-driving farmers (control group) matched for age, gender, generic/ ethnic group, land-holding, and work routines. Objectives. To determine, using magnetic resonance imaging and clinical investigations, the effect of wholebody vibrations on the back in tractor-driving farmers. Summary of Background Data. Low back pain and pathologic changes in the lower backs of tractor drivers have been reported. However, no study with a control group matched for work-related risk factors has been reported. Methods. Fifty tractor-driving farmers were compared with 50 non-tractor-driving farmers matched for age, gender, ethnic group, land-holding, and work routine. Both groups were interviewed for details of work routine, assets held, family profile, and vibration exposure to assess the influence of these parameters on signs and symptoms of backache. Magnetic resonance imaging was done to assess the effect of exposure on whole-body vibration and degenerative changes in the back. Vibration measurements also were done on tractors to observe the actual severity of the vibrations. Results. Regular work-related backache was more common among tractor-driving farmers (40%) than among non-tractor-driving farmers (18%, P ϭ 0.015). Anthropometric evaluation showed abdominal girth and weight to be significantly higher in tractor-driving farmers (P ϭ 0.006 and 0.046, respectively), whereas while height and arm span were similar between the two groups. Clinical examination for evidence of disc or facet degeneration showed no difference between the two groups. Evaluation of magnetic resonance images of tractor-driving farmers and non-tractor-driving farmers by an orthopedic surgeon, radiologist, and neurosurgeon showed degenerative changes to be similar between the two groups (P Ͼ 0.050). Conclusions. Tractor-driving farmers report backache more often than non-tractor-driving farmers, but no significant objective differences on clinical or magnetic resonance imaging evaluation were found between the two groups.

Postgraduate Medical Journal, 1988

We report a case of spontaneous expulsion of a lipoma in a 32 year old male patient who presented... more We report a case of spontaneous expulsion of a lipoma in a 32 year old male patient who presented with recurrent attacks of subacute intestinal obstruction. During one such episode the patient developed unusually severe abdominal pain and expelled a fleshy mass per rectum which, on histopathology, was found to be a lipoma attached to a necrosed portion of the small intestine. The pain disappeared immediately; a subsequent barium meal examination revealed normal appearances and the patient has remained completely symptom free 10 months after the incident.

Cold Spring Harbor perspectives in medicine, Jan 20, 2015

Despite many advances in both diagnosis and treatment, tuberculosis still remains one of commones... more Despite many advances in both diagnosis and treatment, tuberculosis still remains one of commonest causes of morbidity and mortality from any infectious cause in the world. Although the overall incidence and mortality rate for tuberculosis has decreased over the years, timely and accurate diagnosis of tuberculosis is essential for the health of the patient as well as the public. For the diagnosis of tuberculosis, a high degree of clinical suspicion is required, and this becomes much more important in high-risk populations. Tuberculosis may masquerade as any disease; therefore, tissue and microbiological assessment is sometimes important for establishing the diagnosis. However, in daily practice, the clinician and radiologist should be familiar with the imaging features of pulmonary and extrapulmonary tuberculosis, as well as manifestations of tuberculosis in immunocompromised patients. Imaging provides a very important role in the diagnosis and management of tuberculosis. Although c...

Clinical Radiology, 1993

Magnetic resonance imaging (MRI) of the pituitary, hypothalamus and olfactory sulci was performed... more Magnetic resonance imaging (MRI) of the pituitary, hypothalamus and olfactory sulci was performed in 40 patients with idiopathic hypogonadotropic hypogonadism (IHH). Twelve of these patients had an impaired sense of smell (Kallmann's syndrome). Sagittai and coronal imaging revealed no morphological abnormalities in the hypothalamic-pituitary region. On axial imaging rudimentary, hypoplastic or aplastic olfactory sulci were found in eight cases. All patients with olfactory sulcai abnormalities had associated hyposmia (one case) or anosmia (seven cases). Structural defects identifiable on MRI were present only in 20 per cent of patients with IHH.

Journal of Aapos, 2004

FIG 1. (A) Preoperative photograph showing limitation of elevation of the right eye in adduction,... more FIG 1. (A) Preoperative photograph showing limitation of elevation of the right eye in adduction, overelevation of the left eye in adduction, and limitation of depression of left eye in adduction. Head-tilt test shows an upshoot of the left eye on left head tilt. (B) Postoperative photograph showing correction of elevation in adduction of right eye with correction of the inferior oblique overaction of the left eye. Head-tilt test shows no upshoot of the left eye on left head tilt.

Australasian Radiology, 1992

A prospective study was carried out in 100 cases of suspected occult spinal dysraphic anomalies w... more A prospective study was carried out in 100 cases of suspected occult spinal dysraphic anomalies with Magnetic Resonance Imaging in order to determine its diagnostic efficacy as the initial imaging modality. MR imaging provided accurate preoperative information in 91 out of 92 cases (98.9%). Some of the unusual and interesting findings in the series were: presence of intrinsic cord abnormality in 19 out of 21 cases (90.4%) with a normal plain radiograph, 4 cases of diastematomyelia with a dermoid in the dorsal and lumbar region associated with syringohydromyelia, intradural fibrous/glial bands, sgringo-hydromyelia/myelomalacia of the conus with tethered cord syndrome having a normally placed conus, and myelocystocele. It is concluded that MRI is an excellent primary diagnostic tool, together with a plain radiograph, for complete preoperative evaluation of mid-tine spinal anomalies.

MR imaging performed on 1.5 Tesla system in 39 patients of cerebello pontine (CP) angle lesion we... more MR imaging performed on 1.5 Tesla system in 39 patients of cerebello pontine (CP) angle lesion were reviewed and analysed. The commonest lesion encountered was acoustic neuroma (n=11), followed by neuromas of IX– XI (n=5), meningiomas (n=5), epidermoid (n=3), brainstem tumour with exophytic component (n=9), glomus jugulare tumour (m=3), chordoma with an exophytic component (2) leukaemic infiltrate around nerve (1). T1 as well as T2W1 were obtained in all the patients in spin echo sequences. The study concluded MRI is an modality for the evaluation of suspected CP angle lesion because of no bony artifacts, multiplanar imaging and superior soft tissue contrast resolution.

Neurology India, 2010

BackgroundProgressive multifocal leukoencephalopathy (PML) is a deadly demyelinating disease of t... more BackgroundProgressive multifocal leukoencephalopathy (PML) is a deadly demyelinating disease of the brain, caused by reactivation of the polyomavirus JC (JCV). PML has classically been described in individuals with profound cellular immunosuppression such as patients with AIDS, haematological malignancies, organ transplant recipients or those treated with immunosuppressive or immunomodulatory medications for autoimmune diseases.Methods and case reportsThe authors describe five HIV seronegative

Journal of Clinical Neuroscience, 2005

A 13-year-old female presented with two episodes of hemiplegia and hemianopia involving opposite ... more A 13-year-old female presented with two episodes of hemiplegia and hemianopia involving opposite sides, each time associated with seizures. On both occasions, the magnetic resonance (MR) scan showed a giant demyelinating, peripherally enhancing lesion with mass effect. MR spectroscopy (MRS) was indistinguishable from a tumor. At the first episode, she had undergone tumor decompression but the histopathology revealed an acute demyelinating lesion with no evidence of tumor. Each time there was partial clinical recovery and resolution of the radiological lesion, the patient having received corticosteroids during both of the episodes. She also developed hemiballismus postoperatively which resolved on withdrawing phenytoin. It is suggested that a trial of corticosteroids be given in suspected tumefactive demyelinating lesions, although they may be indistinguishable from a tumor. ª

The Journal of the Association of Physicians of India, 1990

The Journal of Obstetrics and Gynecology of India, 2011

Indian Journal of Radiology and Imaging, 2005

Journal of Pediatric Gastroenterology and Nutrition, 1991

Indian pediatrics, 1991

Neurology India, 2003

Postgraduate Medical Journal, 1991

Gut, 1990

Journal of the Indian Medical Association, 1999

Spine, 1999

Postgraduate Medical Journal, 1988

Cold Spring Harbor perspectives in medicine, Jan 20, 2015

Clinical Radiology, 1993

Journal of Aapos, 2004

Australasian Radiology, 1992

Neurology India, 2010

Journal of Clinical Neuroscience, 2005