Pulkit Kalra | Maulana Azad Medical College (original) (raw)
Papers by Pulkit Kalra
Experimental Cell Research
International Orthopaedics, 2020
Flexor tendon adhesion to tissues is one of the most frequent complications reported after flexor... more Flexor tendon adhesion to tissues is one of the most frequent complications reported after flexor tendon repair. The human amniotic membrane (HAM) was used to wrap the tendon repair site to decrease fibrotic response and tendon adhesion. A total of 19 patients with flexor tendon injuries were subjected to surgical repair. The repair site was wrapped with human amniotic membrane (HAM) in nine cases. The remaining ten cases served as controls as no HAM wrap was used. The clinical outcome was assessed by pain, range of motion, and pinch strength. The healing of repair was evaluated with high-frequency ultrasound; the biologic response was assessed with two inflammatory mediators, i.e., interleukin-6 and TGF-beta-1. HAM wrap cases recorded less pain, higher total active range of motion, and better tendon glide on ultrasonography at follow-up (6–18 months). The levels of serum inflammatory biologic markers decreased in majority of HAM cases whereas they increased in controls at two to six weeks post-operatively. No infection/immune rejection phenomenon was seen in HAM wrap cases. HAM wrap around the tendon repair site resulted in quicker function and qualitatively better tendon healing on ultrasound, with a decrease of the biologic response.
JBJS Case Connector, 2020
CASE A 15-year-old boy presented with intermittent pain, in the left nondominant hand, for the pa... more CASE A 15-year-old boy presented with intermittent pain, in the left nondominant hand, for the past 3 years. He recently developed numbness in the radial 3 and a half digits. Ultrasonography revealed a bifid median nerve (BMN) with a persistent median artery (PMA). An open carpal tunnel release was performed, which revealed an accessory lumbrical muscle in addition to the BMN and a PMA. CONCLUSION The surgeon should be aware of the possible coexistence of 3 anomalous structures while performing carpal tunnel release in a young patient.
The Journal of Hand Surgery (Asian-Pacific Volume), 2020
Background: Leprous neuropathy is a significant, yet preventable, cause of disability worldwide. ... more Background: Leprous neuropathy is a significant, yet preventable, cause of disability worldwide. Decompressive surgery and oral steroids have been used along with Multi Drug Therapy (MDT) for treating leprous neuropathy with varied success as reported in literature. Methods: We prospectively studied 16 peripheral nerves in 10 patients with leprous neuropathy of less than a year duration and not responding to steroid therapy in 3 weeks. The patients were divided into 2 groups: Group-A (decompressive nerve surgery was done within 12 weeks of onset of neurological deficit), and Group-B (nerve decompression was performed after 12 weeks from onset of neurological deficit). Post-operatively patients were assessed for regression of deformity, sensory, motor, vasomotor recovery and neuropathic pain. Results: Median age of patients was 32 years (range; 18 years to 46 years). Mean motor score and mean grip strength was significantly better for group A patients at 2 years follow-up (p < 0.0...
JBJS Case Connector, 2020
CASE We present a rare combined convergent-divergent carpometacarpal (CMC) fracture dislocation w... more CASE We present a rare combined convergent-divergent carpometacarpal (CMC) fracture dislocation with median nerve involvement in a young adult after a motorbike accident. Radiographs revealed a volar dislocation of the second and fifth metacarpals and dorsal dislocation of the third and fourth metacarpals with bases of the second and fifth metacarpals found to be converging in the coronal plane. Open reduction and fixation was performed with carpal tunnel release. CONCLUSION Combined convergent-divergent CMC fracture dislocation should be kept as a differential while evaluating CMC dislocations. Metacarpal cascade line (posteroanterior view) and 2 lateral views (radial side up and ulnar side up) with computed tomography scan (3-dimensional reconstruction) prove to be vital in such high-energy trauma.
Journal of Orthopaedic Surgery, 2020
Introduction: Surgical intervention through the ‘triangle of auscultation’ is less morbid to pati... more Introduction: Surgical intervention through the ‘triangle of auscultation’ is less morbid to patients, as it is devoid of muscles and provides an easy access to tumours arising on the ventral aspect of scapula especially near inferior angle. Method: Three patients presented to us with pseudo-winging of scapula and an audible thud on abduction of the arm. A bony mass, painful in two and painless in one patient, was palpable along the anterior aspect of the inferior angle of scapula. A clinical diagnosis of osteochondroma was made which was corroborated by X-rays and computed tomography (CT) imaging. Ventral scapular osteochondroma excision is challenging due to multiple muscle attachments, requiring extensive soft tissue dissection and muscular release. Numerous blood vessels and nerves in the vicinity may also add to the degree of difficulty. This necessitates the need of a minimally invasive and muscle-sparing procedure. We hereby describe a novel surgical approach to the ventral a...
Purpose Resuming joint replacement arthroplasty amidst the COVID-19 pandemic and lockdown has com... more Purpose Resuming joint replacement arthroplasty amidst the COVID-19 pandemic and lockdown has come with various challenges that had to be dealt with utmost caution. Patients with severe arthritis experiencing a state of intolerable pain, could not be left unaddressed. Guidelines published by surgical associations, collaborative surgical author groups including public health organisations had to be modified to suit the Indian scenario and obtain optimal functional outcomes in these patients. Methods A retrospective cohort analysis of 147 patients who underwent arthroplasty during the pandemic (March 2020 to April 2021), for either primary or secondary arthritis, was performed. We assess the efficacy and safety of the newly established Institutional surgical peri-operative protocol at our tertiary care centre in the National Capital Region, India in response to COVID-19 guidelines. The primary outcome measures appraised was 30-day mortality and the secondary outcome measures included ...
CASE A 9-year-old girl, with a history of crush injury to her right hand 2 years ago, presented w... more CASE A 9-year-old girl, with a history of crush injury to her right hand 2 years ago, presented with inability to extend her index finger. Exploration revealed segmental loss of extensor tendons to the index finger with a pre-existing scar in the route of tendon transfer. The juncturae tendinum (JT) between extensor digitorum communis of the middle and ring fingers (Von Schroeder -3y) was transferred to reconstruct the extensor tendon. At 1-year follow-up, finger extension was restored, with improved grasp and release. CONCLUSION JT transfer could prove useful in reconstructing zone II extensor tendon injuries with scarring and fibrosis in the route of conventional tendon transfer/graft.
International Orthopaedics
Experimental Cell Research
International Orthopaedics, 2020
Flexor tendon adhesion to tissues is one of the most frequent complications reported after flexor... more Flexor tendon adhesion to tissues is one of the most frequent complications reported after flexor tendon repair. The human amniotic membrane (HAM) was used to wrap the tendon repair site to decrease fibrotic response and tendon adhesion. A total of 19 patients with flexor tendon injuries were subjected to surgical repair. The repair site was wrapped with human amniotic membrane (HAM) in nine cases. The remaining ten cases served as controls as no HAM wrap was used. The clinical outcome was assessed by pain, range of motion, and pinch strength. The healing of repair was evaluated with high-frequency ultrasound; the biologic response was assessed with two inflammatory mediators, i.e., interleukin-6 and TGF-beta-1. HAM wrap cases recorded less pain, higher total active range of motion, and better tendon glide on ultrasonography at follow-up (6–18 months). The levels of serum inflammatory biologic markers decreased in majority of HAM cases whereas they increased in controls at two to six weeks post-operatively. No infection/immune rejection phenomenon was seen in HAM wrap cases. HAM wrap around the tendon repair site resulted in quicker function and qualitatively better tendon healing on ultrasound, with a decrease of the biologic response.
JBJS Case Connector, 2020
CASE A 15-year-old boy presented with intermittent pain, in the left nondominant hand, for the pa... more CASE A 15-year-old boy presented with intermittent pain, in the left nondominant hand, for the past 3 years. He recently developed numbness in the radial 3 and a half digits. Ultrasonography revealed a bifid median nerve (BMN) with a persistent median artery (PMA). An open carpal tunnel release was performed, which revealed an accessory lumbrical muscle in addition to the BMN and a PMA. CONCLUSION The surgeon should be aware of the possible coexistence of 3 anomalous structures while performing carpal tunnel release in a young patient.
The Journal of Hand Surgery (Asian-Pacific Volume), 2020
Background: Leprous neuropathy is a significant, yet preventable, cause of disability worldwide. ... more Background: Leprous neuropathy is a significant, yet preventable, cause of disability worldwide. Decompressive surgery and oral steroids have been used along with Multi Drug Therapy (MDT) for treating leprous neuropathy with varied success as reported in literature. Methods: We prospectively studied 16 peripheral nerves in 10 patients with leprous neuropathy of less than a year duration and not responding to steroid therapy in 3 weeks. The patients were divided into 2 groups: Group-A (decompressive nerve surgery was done within 12 weeks of onset of neurological deficit), and Group-B (nerve decompression was performed after 12 weeks from onset of neurological deficit). Post-operatively patients were assessed for regression of deformity, sensory, motor, vasomotor recovery and neuropathic pain. Results: Median age of patients was 32 years (range; 18 years to 46 years). Mean motor score and mean grip strength was significantly better for group A patients at 2 years follow-up (p < 0.0...
JBJS Case Connector, 2020
CASE We present a rare combined convergent-divergent carpometacarpal (CMC) fracture dislocation w... more CASE We present a rare combined convergent-divergent carpometacarpal (CMC) fracture dislocation with median nerve involvement in a young adult after a motorbike accident. Radiographs revealed a volar dislocation of the second and fifth metacarpals and dorsal dislocation of the third and fourth metacarpals with bases of the second and fifth metacarpals found to be converging in the coronal plane. Open reduction and fixation was performed with carpal tunnel release. CONCLUSION Combined convergent-divergent CMC fracture dislocation should be kept as a differential while evaluating CMC dislocations. Metacarpal cascade line (posteroanterior view) and 2 lateral views (radial side up and ulnar side up) with computed tomography scan (3-dimensional reconstruction) prove to be vital in such high-energy trauma.
Journal of Orthopaedic Surgery, 2020
Introduction: Surgical intervention through the ‘triangle of auscultation’ is less morbid to pati... more Introduction: Surgical intervention through the ‘triangle of auscultation’ is less morbid to patients, as it is devoid of muscles and provides an easy access to tumours arising on the ventral aspect of scapula especially near inferior angle. Method: Three patients presented to us with pseudo-winging of scapula and an audible thud on abduction of the arm. A bony mass, painful in two and painless in one patient, was palpable along the anterior aspect of the inferior angle of scapula. A clinical diagnosis of osteochondroma was made which was corroborated by X-rays and computed tomography (CT) imaging. Ventral scapular osteochondroma excision is challenging due to multiple muscle attachments, requiring extensive soft tissue dissection and muscular release. Numerous blood vessels and nerves in the vicinity may also add to the degree of difficulty. This necessitates the need of a minimally invasive and muscle-sparing procedure. We hereby describe a novel surgical approach to the ventral a...
Purpose Resuming joint replacement arthroplasty amidst the COVID-19 pandemic and lockdown has com... more Purpose Resuming joint replacement arthroplasty amidst the COVID-19 pandemic and lockdown has come with various challenges that had to be dealt with utmost caution. Patients with severe arthritis experiencing a state of intolerable pain, could not be left unaddressed. Guidelines published by surgical associations, collaborative surgical author groups including public health organisations had to be modified to suit the Indian scenario and obtain optimal functional outcomes in these patients. Methods A retrospective cohort analysis of 147 patients who underwent arthroplasty during the pandemic (March 2020 to April 2021), for either primary or secondary arthritis, was performed. We assess the efficacy and safety of the newly established Institutional surgical peri-operative protocol at our tertiary care centre in the National Capital Region, India in response to COVID-19 guidelines. The primary outcome measures appraised was 30-day mortality and the secondary outcome measures included ...
CASE A 9-year-old girl, with a history of crush injury to her right hand 2 years ago, presented w... more CASE A 9-year-old girl, with a history of crush injury to her right hand 2 years ago, presented with inability to extend her index finger. Exploration revealed segmental loss of extensor tendons to the index finger with a pre-existing scar in the route of tendon transfer. The juncturae tendinum (JT) between extensor digitorum communis of the middle and ring fingers (Von Schroeder -3y) was transferred to reconstruct the extensor tendon. At 1-year follow-up, finger extension was restored, with improved grasp and release. CONCLUSION JT transfer could prove useful in reconstructing zone II extensor tendon injuries with scarring and fibrosis in the route of conventional tendon transfer/graft.
International Orthopaedics