Marina Tsetlin | Moscow State University of Psychology and Education (original) (raw)
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Papers by Marina Tsetlin
Cortex, Jan 1, 2011
Autism spectrum disorder Preschool children Gamma oscillations a b s t r a c t Illusory contour (... more Autism spectrum disorder Preschool children Gamma oscillations a b s t r a c t Illusory contour (IC) perception, a fruitful model for studying the automatic contextual integration of local image features, can be used to investigate the putative impairment of such integration in children with autism spectrum disorders (ASD). We used the illusory Kanizsa square to test how the phase-locked (PL) gamma and beta electroencephalogram (EEG) responses of typically developing (TD) children aged 3e7 years and those with ASD were modulated by the presence of IC in the image. The PL beta and gamma activity strongly differentiated between IC and control figures in both groups of children (IC effect).
Clinical …, Jan 1, 2007
Objective: Functional brain abnormalities associated with autism in 3-8-year-old boys were studie... more Objective: Functional brain abnormalities associated with autism in 3-8-year-old boys were studied with EEG recorded under controlled experimental condition of sustained visual attention and behavioral stillness. Methods: EEG was recorded in two independent samples of boys with autism (BWA) from Moscow (N = 21) and Gothenburg (N = 23) and a corresponding number of age-matched typically developing boys (TDB). EEG spectral power (SP) and SP interhemispheric asymmetry within delta, theta and alpha bands were analyzed. Results: BWA comprised a non-homogeneous group in relation to theta and alpha SP. When four outliers were excluded the only between-group difference in absolute SP was a higher amount of prefrontal delta in BWA. BWA of both samples demonstrated atypical leftward broadband EEG asymmetry with a maximum effect over the mid-temporal regions. Concurrently, the normal leftward asymmetry of mu rhythm was absent in BWA. Conclusions: The abnormal broadband EEG asymmetry in autism may point to a diminished capacity of right temporal cortex to generate EEG rhythms. The concurrent lack of normal leftward asymmetry of mu rhythm suggests that abnormalities in EEG lateralization in autism may be regionally/functionally specific. Significance: The data provide evidence for abnormal functional brain lateralization in autism.
Biological …, Jan 1, 2007
Background: An elevated excitation/inhibition ratio has been suggested as one mechanism underpinn... more Background: An elevated excitation/inhibition ratio has been suggested as one mechanism underpinning autism. An imbalance between cortical excitation and inhibition may manifest itself in electroencephalogram (EEG) abnormalities in the high frequency range. The aim of this study was to investigate whether beta and gamma range EEG abnormalities are characteristic for young boys with autism (BWA).
Cortex, Jan 1, 2011
Autism spectrum disorder Preschool children Gamma oscillations a b s t r a c t Illusory contour (... more Autism spectrum disorder Preschool children Gamma oscillations a b s t r a c t Illusory contour (IC) perception, a fruitful model for studying the automatic contextual integration of local image features, can be used to investigate the putative impairment of such integration in children with autism spectrum disorders (ASD). We used the illusory Kanizsa square to test how the phase-locked (PL) gamma and beta electroencephalogram (EEG) responses of typically developing (TD) children aged 3e7 years and those with ASD were modulated by the presence of IC in the image. The PL beta and gamma activity strongly differentiated between IC and control figures in both groups of children (IC effect).
Clinical …, Jan 1, 2007
Objective: Functional brain abnormalities associated with autism in 3-8-year-old boys were studie... more Objective: Functional brain abnormalities associated with autism in 3-8-year-old boys were studied with EEG recorded under controlled experimental condition of sustained visual attention and behavioral stillness. Methods: EEG was recorded in two independent samples of boys with autism (BWA) from Moscow (N = 21) and Gothenburg (N = 23) and a corresponding number of age-matched typically developing boys (TDB). EEG spectral power (SP) and SP interhemispheric asymmetry within delta, theta and alpha bands were analyzed. Results: BWA comprised a non-homogeneous group in relation to theta and alpha SP. When four outliers were excluded the only between-group difference in absolute SP was a higher amount of prefrontal delta in BWA. BWA of both samples demonstrated atypical leftward broadband EEG asymmetry with a maximum effect over the mid-temporal regions. Concurrently, the normal leftward asymmetry of mu rhythm was absent in BWA. Conclusions: The abnormal broadband EEG asymmetry in autism may point to a diminished capacity of right temporal cortex to generate EEG rhythms. The concurrent lack of normal leftward asymmetry of mu rhythm suggests that abnormalities in EEG lateralization in autism may be regionally/functionally specific. Significance: The data provide evidence for abnormal functional brain lateralization in autism.
Biological …, Jan 1, 2007
Background: An elevated excitation/inhibition ratio has been suggested as one mechanism underpinn... more Background: An elevated excitation/inhibition ratio has been suggested as one mechanism underpinning autism. An imbalance between cortical excitation and inhibition may manifest itself in electroencephalogram (EEG) abnormalities in the high frequency range. The aim of this study was to investigate whether beta and gamma range EEG abnormalities are characteristic for young boys with autism (BWA).