Poonam mondal | Malaviya National Institute of Technology, Jaipur (original) (raw)
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Biomaterials are materials which are either present naturally or synthesized in-vitro which are i... more Biomaterials are materials which are either present naturally or synthesized in-vitro which are in contact with biological system and have various medical applications. Biomaterials are widely used now a day due to its non-viable properties and it can also be used as implants like Hydroxyapatite. Hydroxyapatite (Hap) is a biomaterial which is porous and granulated in nature and has wide application in biomedical, dentistry and orthopedics. Hydroxyapatite is biocompatible, non-toxic, non-inflammatory and even non-immunogenic agent. The present report illustrates the synthesis and characterization of Hap powder using precipitation method and evaluation of its biodegradability. Precipitation method is employed because Hap obtained after synthesis from this method will be in the pure form. It was analyzed that the sample is completely biodegradable. It is a compound of great interest mostly because of its chemical similarity to the mineral component of bones and its wide application in various fields.
The anti-oxidant activity and total phenolic content of alcoholic extracts from seven medicinal p... more The anti-oxidant activity and total phenolic content of alcoholic extracts from seven medicinal plants (Asparagus racemosus, Ocimum sanctum, Cassia fistula, Piper betel, Citrus aurantifolia, Catharanthus roseus, and Polyalthia longifolia) were evaluated by using a model system consisting of β-carotene, DPPH free radical and Folin-Ciocalteu method. The total Phenolic content of the extracts was determined spectrophotometrically according to the Folin-Ciocalteu procedure and ranged from 366mg/100g to 212 mg/100g on fresh weight basis. The total flavanoid content of extracts determined by Aluminium chloride colorimetric assay and ranged from 39.84mg/100g to 15.94mg/100g of fresh weight. The highest antioxidant activity was demonstrated by Citrus auantifolia (87.05%) followed by Ocimum sanctum (81.80%) and Catharanthus roseus (71.4%). The highest tannin content was found to be in Catharanthus roseus (7.14%) while in case of anthocyanin content the highest value was found to be in Polyalthia longifolia (0.65mg/l). As far as antimicrobial activity is concerned, Ocimum sanctum and Citrus aurantifolia were found to be most potent against Escherichia coli and Staphylococcus aureus whereas Piper betel showed no effect. Except Piper betel all the extracts were able to inhibit the two bacterial strains and the zone of inhibitions ranged from 19.6 mm to 13.5 mm. The minimum inhibitory concentration against E. coli in case of Ocimum sanctum is 10% and against S. aureus it is 20% while in case of Citrus aurantifolia extracts were active even at 10% concentration for E. coli and 15% for S. aureus.
A higher level of fluoride in drinking water poses serious health hazards to humans. Fluoride acc... more A higher level of fluoride in drinking water poses serious health hazards to humans. Fluoride accumulates in bones and teeth in the form of fluorapatite which causes the bones to become brittle. Oral intake of fluoride higher than 1.0 to 1.5mg/L results in skeletal and dental fluorosis. Batch experiments were carried out to investigate the removal of fluoride from acid treated water by using calcite as the adsorbent. The effect of calcite dosage with different concentrations of acetic acid on defluoridation capacity was evaluated. The removal efficiency of fluoride increased with increase in the dose of calcite. Calcite is found to be a very low cost material and treating it with 0.05M acetic acid has resulted in increasing the defluoridation capacity to 75.6%. For a dosage of 7gm/l of calcite used for treating water with acetic acid the removal was 65.03% and the pH of treated water was observed to be 6.7 to 7.4 which makes it fit for drinking purposes. Results obtained depicted that the defluoridation is due to both adsorption and precipitation processes. It was found that the acidified water was neutralized by calcite and the pH of treated water was in the range of 6.7 to 7.4 after treatment. This study indicated that calcite is a very low cost adsorbent and can be used as a defluoridation agent.
Biomaterials are materials which are either present naturally or synthesized in-vitro which are i... more Biomaterials are materials which are either present naturally or synthesized in-vitro which are in contact with biological system and have various medical applications. Biomaterials are widely used now a day due to its non-viable properties and it can also be used as implants like Hydroxyapatite. Hydroxyapatite (Hap) is a biomaterial which is porous and granulated in nature and has wide application in biomedical, dentistry and orthopedics. Hydroxyapatite is biocompatible, non-toxic, non-inflammatory and even non-immunogenic agent. The present report illustrates the synthesis and characterization of Hap powder using precipitation method and evaluation of its biodegradability. Precipitation method is employed because Hap obtained after synthesis from this method will be in the pure form. It was analyzed that the sample is completely biodegradable. It is a compound of great interest mostly because of its chemical similarity to the mineral component of bones and its wide application in various fields.
The anti-oxidant activity and total phenolic content of alcoholic extracts from seven medicinal p... more The anti-oxidant activity and total phenolic content of alcoholic extracts from seven medicinal plants (Asparagus racemosus, Ocimum sanctum, Cassia fistula, Piper betel, Citrus aurantifolia, Catharanthus roseus, and Polyalthia longifolia) were evaluated by using a model system consisting of β-carotene, DPPH free radical and Folin-Ciocalteu method. The total Phenolic content of the extracts was determined spectrophotometrically according to the Folin-Ciocalteu procedure and ranged from 366mg/100g to 212 mg/100g on fresh weight basis. The total flavanoid content of extracts determined by Aluminium chloride colorimetric assay and ranged from 39.84mg/100g to 15.94mg/100g of fresh weight. The highest antioxidant activity was demonstrated by Citrus auantifolia (87.05%) followed by Ocimum sanctum (81.80%) and Catharanthus roseus (71.4%). The highest tannin content was found to be in Catharanthus roseus (7.14%) while in case of anthocyanin content the highest value was found to be in Polyalthia longifolia (0.65mg/l). As far as antimicrobial activity is concerned, Ocimum sanctum and Citrus aurantifolia were found to be most potent against Escherichia coli and Staphylococcus aureus whereas Piper betel showed no effect. Except Piper betel all the extracts were able to inhibit the two bacterial strains and the zone of inhibitions ranged from 19.6 mm to 13.5 mm. The minimum inhibitory concentration against E. coli in case of Ocimum sanctum is 10% and against S. aureus it is 20% while in case of Citrus aurantifolia extracts were active even at 10% concentration for E. coli and 15% for S. aureus.
A higher level of fluoride in drinking water poses serious health hazards to humans. Fluoride acc... more A higher level of fluoride in drinking water poses serious health hazards to humans. Fluoride accumulates in bones and teeth in the form of fluorapatite which causes the bones to become brittle. Oral intake of fluoride higher than 1.0 to 1.5mg/L results in skeletal and dental fluorosis. Batch experiments were carried out to investigate the removal of fluoride from acid treated water by using calcite as the adsorbent. The effect of calcite dosage with different concentrations of acetic acid on defluoridation capacity was evaluated. The removal efficiency of fluoride increased with increase in the dose of calcite. Calcite is found to be a very low cost material and treating it with 0.05M acetic acid has resulted in increasing the defluoridation capacity to 75.6%. For a dosage of 7gm/l of calcite used for treating water with acetic acid the removal was 65.03% and the pH of treated water was observed to be 6.7 to 7.4 which makes it fit for drinking purposes. Results obtained depicted that the defluoridation is due to both adsorption and precipitation processes. It was found that the acidified water was neutralized by calcite and the pH of treated water was in the range of 6.7 to 7.4 after treatment. This study indicated that calcite is a very low cost adsorbent and can be used as a defluoridation agent.