Affette McCaw-binns | The University of the West Indies, Mona, Jamaica (original) (raw)
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Papers by Affette McCaw-binns
International Journal of Epidemiology, 2001
Journal of Obstetrics & Gynaecology, 2006
A prevalence survey of anticardiolipin antibodies (aCL) was done among 924 primiparae. aCL were m... more A prevalence survey of anticardiolipin antibodies (aCL) was done among 924 primiparae. aCL were measured in serum by the standardised anticardiolipin enzyme linked immunosorbent assays (ELISA) and beta(2)-glycoprotein 1 assays to determine the seroprevalence of both beta(2) glycoprotein 1 dependent aCL and beta(2)-glycoprotein 1 independent aCL in Jamaican primiparae, to determine whether aCL are associated with abnormal pregnancy outcomes and if treatment with aspirin had any effect on pregnancy outcome in aCL positive primiparae. The prevalence of aCL was (32/671) 4.8% (95%CI 3.2-6.4) in women who were tested twice. A total of 49 of 924 primiparae or 5.3% (95%CI 3.9-6.7) were positive for aCL on at least one occasion. Only three of the 32 primiparae 3/32 (9.4%) who were positive for aCL on two occasions were positive for beta(2)-glycoprotein 1 dependent aCL. Pregnancy outcome did not differ significantly with respect to aCL status. Aspirin therapy did not influence pregnancy outcome in the 49 aCL positive primiparae studied.
Journal of clinical epidemiology, Jan 7, 2015
Describe the completeness and quality of Jamaica's 2008 vital registration mortality database... more Describe the completeness and quality of Jamaica's 2008 vital registration mortality database. Multiple sources (hospitals, police, forensic pathologists, Coroners courts) were used to validate deaths registered as occurring in 2008. A 10% random sample was examined to evaluate the quality of certification and coding. Jamaica, a middle-income country of 2.7 million, began vital registration in 1877; however, the mortality database was considered of limited use, and the study was commissioned to understand the problem. Of 19,286 deaths identified, 76% were registered by 31.12.2009 for inclusion among 2008 demographic returns. Registration was highest among deaths not requiring autopsy (94%) and lowest among Coroners cases (22%) with only 41% of deaths among 15-44 year-olds registered. The leading causes of death were cerebrovascular disease, diabetes mellitus, and homicide. Fifteen percent were coded to ill-defined causes of death. Recoding the sample increased mortality from pre...
Education for Health: Change in Learning & Practice, 2005
Context: During a family health clerkship at the University of The West Indies, students are expe... more Context: During a family health clerkship at the University of The West Indies, students are expected to acquire individual and community diagnosis skills and the ability to relate the two, as well as acquire knowledge of other community agencies involved in health care. Objective: To determine the main assumptions related to disease treatment, which students have had to re-think after
International Journal of Gynecology & Obstetrics, 2004
Objective: To assess the efficacy and acceptability of a patient-held pictorial card aimed at rai... more Objective: To assess the efficacy and acceptability of a patient-held pictorial card aimed at raising awareness and appropriate health seeking behavior in response to prodromal symptoms of imminent eclampsia. Method: Pictorial cards (and posters) were issued to antenatal clinics and used to focus instruction and advice to pregnant women. Mothers were surveyed before and after the cards were introduced to
Lancet, 2010
New modelled estimates of maternal mortality. By - Ariel Frisancho.
Paediatric and Perinatal Epidemiology, 1994
International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics, 2015
To identify why vital registration under-reports maternal deaths in Jamaica. A cross-sectional st... more To identify why vital registration under-reports maternal deaths in Jamaica. A cross-sectional study was undertaken to identify all maternal deaths (during pregnancy or ≤42 days after pregnancy ended) occurring in 2008. Data sources included vital registration, hospital records, forensic pathology records, and an independent maternal mortality surveillance system. Potential cases were cross-referenced to registered live births and stillbirths, and hospital records to confirm pregnancy status, when the pregnancy ended, and registration. Medical certificates were inspected for certification, transcription, and coding errors. Maternal mortality ratios (MMRs) for registered and/or unregistered deaths were calculated. Of 50 maternal deaths identified, 10 (20%) were unregistered. Eight unregistered deaths were coroners' cases. Among 40 registered deaths, pregnancy was undocumented in 4 (10%). Among the other 36, 24 (67%) had been misclassified (59% direct and 89% indirect deaths). The...
International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics, 2009
Journal of Clinical Epidemiology, 2015
In this study, we examined the effects of birth weight (BWT) and early life socioeconomic circums... more In this study, we examined the effects of birth weight (BWT) and early life socioeconomic circumstances (SEC) on systolic blood pressure (SBP) and diastolic blood pressure (DBP) among Jamaican young adults. Longitudinal study of 364 men and 430 women from the Jamaica 1986 Birth Cohort Study. Information on BWT and maternal SEC at child's birth was linked to information collected at 18-20 years old. Sex-specific multilevel linear regression models were used to examine whether adult SBP/DBP was associated with BWT and maternal SEC. In unadjusted models, SBP was inversely related to BWT z-score in both men (β, -0.82 mm Hg) and women (β, -1.18 mm Hg) but achieved statistical significance for women only. In the fully adjusted model, one standard deviation increase in BWT was associated with 1.16 mm Hg reduction in SBP among men [95% confidence interval (CI): 2.15, 0.17; P = 0.021] and 1.34 mm Hg reduction in SBP among women (95% CI: 2.21, 0.47; P = 0.003). Participants whose mothers had lower SEC had higher SBP compared with those with mothers of high SEC (β, 3.4-4.8 mm Hg for men, P < 0.05 for all SEC categories and 1.8-2.1 for women, P > 0.05). SBP was inversely related to maternal SEC and BWT among Jamaican young adults.
Paediatric and Perinatal Epidemiology, 2001
In order to identify the factors associated with admission to neonatal care units in a developing... more In order to identify the factors associated with admission to neonatal care units in a developing country, 1,823 newborns admitted to Jamaica's eight neonatal care units over a 6-month period were compared with 9,563 newborns identified during an island-wide population morbidity study. Maternal sociodemographic characteristics, past obstetric history, infant's growth parameters at birth and mode and place of delivery were investigated. Babies of mothers resident in the two regions of the island where specialist paediatric services were available had increased odds of admission (OR= 1.45, 1.22) compared with those living elsewhere (OR=0.70, 0.80). Maternal history of a previous miscarriage, termination or early neonatal death were associated with subsequent admission, but a previous stillbirth or late neonatal death were not. Very low birthweight infants of gestational age 28-31 weeks were more likely to be admitted than those < 28 weeks with ORs of 1.45 and 0.34 respectively. Factors determining neonatal admission in the developing world may be quite different from those of developed countries. The development of guidelines and support services to ensure wider access to these services for those most in need could contribute to more equitable utilisation of services.
West Indian Medical Journal, 2006
West Indian Medical Journal, 2006
Social Science & Medicine, 1995
Paediatric and Perinatal Epidemiology, 1988
International Journal of Epidemiology, 2001
Journal of Obstetrics & Gynaecology, 2006
A prevalence survey of anticardiolipin antibodies (aCL) was done among 924 primiparae. aCL were m... more A prevalence survey of anticardiolipin antibodies (aCL) was done among 924 primiparae. aCL were measured in serum by the standardised anticardiolipin enzyme linked immunosorbent assays (ELISA) and beta(2)-glycoprotein 1 assays to determine the seroprevalence of both beta(2) glycoprotein 1 dependent aCL and beta(2)-glycoprotein 1 independent aCL in Jamaican primiparae, to determine whether aCL are associated with abnormal pregnancy outcomes and if treatment with aspirin had any effect on pregnancy outcome in aCL positive primiparae. The prevalence of aCL was (32/671) 4.8% (95%CI 3.2-6.4) in women who were tested twice. A total of 49 of 924 primiparae or 5.3% (95%CI 3.9-6.7) were positive for aCL on at least one occasion. Only three of the 32 primiparae 3/32 (9.4%) who were positive for aCL on two occasions were positive for beta(2)-glycoprotein 1 dependent aCL. Pregnancy outcome did not differ significantly with respect to aCL status. Aspirin therapy did not influence pregnancy outcome in the 49 aCL positive primiparae studied.
Journal of clinical epidemiology, Jan 7, 2015
Describe the completeness and quality of Jamaica's 2008 vital registration mortality database... more Describe the completeness and quality of Jamaica's 2008 vital registration mortality database. Multiple sources (hospitals, police, forensic pathologists, Coroners courts) were used to validate deaths registered as occurring in 2008. A 10% random sample was examined to evaluate the quality of certification and coding. Jamaica, a middle-income country of 2.7 million, began vital registration in 1877; however, the mortality database was considered of limited use, and the study was commissioned to understand the problem. Of 19,286 deaths identified, 76% were registered by 31.12.2009 for inclusion among 2008 demographic returns. Registration was highest among deaths not requiring autopsy (94%) and lowest among Coroners cases (22%) with only 41% of deaths among 15-44 year-olds registered. The leading causes of death were cerebrovascular disease, diabetes mellitus, and homicide. Fifteen percent were coded to ill-defined causes of death. Recoding the sample increased mortality from pre...
Education for Health: Change in Learning & Practice, 2005
Context: During a family health clerkship at the University of The West Indies, students are expe... more Context: During a family health clerkship at the University of The West Indies, students are expected to acquire individual and community diagnosis skills and the ability to relate the two, as well as acquire knowledge of other community agencies involved in health care. Objective: To determine the main assumptions related to disease treatment, which students have had to re-think after
International Journal of Gynecology & Obstetrics, 2004
Objective: To assess the efficacy and acceptability of a patient-held pictorial card aimed at rai... more Objective: To assess the efficacy and acceptability of a patient-held pictorial card aimed at raising awareness and appropriate health seeking behavior in response to prodromal symptoms of imminent eclampsia. Method: Pictorial cards (and posters) were issued to antenatal clinics and used to focus instruction and advice to pregnant women. Mothers were surveyed before and after the cards were introduced to
Lancet, 2010
New modelled estimates of maternal mortality. By - Ariel Frisancho.
Paediatric and Perinatal Epidemiology, 1994
International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics, 2015
To identify why vital registration under-reports maternal deaths in Jamaica. A cross-sectional st... more To identify why vital registration under-reports maternal deaths in Jamaica. A cross-sectional study was undertaken to identify all maternal deaths (during pregnancy or ≤42 days after pregnancy ended) occurring in 2008. Data sources included vital registration, hospital records, forensic pathology records, and an independent maternal mortality surveillance system. Potential cases were cross-referenced to registered live births and stillbirths, and hospital records to confirm pregnancy status, when the pregnancy ended, and registration. Medical certificates were inspected for certification, transcription, and coding errors. Maternal mortality ratios (MMRs) for registered and/or unregistered deaths were calculated. Of 50 maternal deaths identified, 10 (20%) were unregistered. Eight unregistered deaths were coroners' cases. Among 40 registered deaths, pregnancy was undocumented in 4 (10%). Among the other 36, 24 (67%) had been misclassified (59% direct and 89% indirect deaths). The...
International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics, 2009
Journal of Clinical Epidemiology, 2015
In this study, we examined the effects of birth weight (BWT) and early life socioeconomic circums... more In this study, we examined the effects of birth weight (BWT) and early life socioeconomic circumstances (SEC) on systolic blood pressure (SBP) and diastolic blood pressure (DBP) among Jamaican young adults. Longitudinal study of 364 men and 430 women from the Jamaica 1986 Birth Cohort Study. Information on BWT and maternal SEC at child's birth was linked to information collected at 18-20 years old. Sex-specific multilevel linear regression models were used to examine whether adult SBP/DBP was associated with BWT and maternal SEC. In unadjusted models, SBP was inversely related to BWT z-score in both men (β, -0.82 mm Hg) and women (β, -1.18 mm Hg) but achieved statistical significance for women only. In the fully adjusted model, one standard deviation increase in BWT was associated with 1.16 mm Hg reduction in SBP among men [95% confidence interval (CI): 2.15, 0.17; P = 0.021] and 1.34 mm Hg reduction in SBP among women (95% CI: 2.21, 0.47; P = 0.003). Participants whose mothers had lower SEC had higher SBP compared with those with mothers of high SEC (β, 3.4-4.8 mm Hg for men, P < 0.05 for all SEC categories and 1.8-2.1 for women, P > 0.05). SBP was inversely related to maternal SEC and BWT among Jamaican young adults.
Paediatric and Perinatal Epidemiology, 2001
In order to identify the factors associated with admission to neonatal care units in a developing... more In order to identify the factors associated with admission to neonatal care units in a developing country, 1,823 newborns admitted to Jamaica's eight neonatal care units over a 6-month period were compared with 9,563 newborns identified during an island-wide population morbidity study. Maternal sociodemographic characteristics, past obstetric history, infant's growth parameters at birth and mode and place of delivery were investigated. Babies of mothers resident in the two regions of the island where specialist paediatric services were available had increased odds of admission (OR= 1.45, 1.22) compared with those living elsewhere (OR=0.70, 0.80). Maternal history of a previous miscarriage, termination or early neonatal death were associated with subsequent admission, but a previous stillbirth or late neonatal death were not. Very low birthweight infants of gestational age 28-31 weeks were more likely to be admitted than those < 28 weeks with ORs of 1.45 and 0.34 respectively. Factors determining neonatal admission in the developing world may be quite different from those of developed countries. The development of guidelines and support services to ensure wider access to these services for those most in need could contribute to more equitable utilisation of services.
West Indian Medical Journal, 2006
West Indian Medical Journal, 2006
Social Science & Medicine, 1995
Paediatric and Perinatal Epidemiology, 1988