Pruthviraj Jaybhaye | University of Mumbai (original) (raw)

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Papers by Pruthviraj Jaybhaye

Journal of Cancer Research and Therapeutics, 2016

Pure endobronchial neoplasms are a rare entity, and they may present with diverse pathological fi... more Pure endobronchial neoplasms are a rare entity, and they may present with diverse pathological findings. Malignant diseases are more common than benign ones, and they mostly originate from the surface epithelium. Endobronchial tumors usually present with symptoms such as cough, hemoptysis, recurrent pneumonia, wheezing, and chest pain. Flexible bronchoscopy is necessary for diagnosis and evaluation of these endobronchial tumors. Advance bronchoscopy or definitive surgery is the modality of treatment for these tumors based on the presentation. We present a case series of patients suffering from different rare endobronchial tumors and their management along with the review of literature.

National Journal of Integrated Research in Medicine, 2012

Aim: Although urine culture is used as the reference standard to determine presence or absence of... more Aim: Although urine culture is used as the reference standard to determine presence or absence of urinary tract infection (UTI), culture is an expensive and time-consuming method. The objectives of the study were to compare automated dipstick urinalysis with microscopic urinalysis and form an algorithm to reduce time and labour of the pathologist and faster initiation of treatment to the patient. Method: 500 morning urine samples were analysed by using automated dipstick analyser( Cobas u 411) and those samples showing abnormal results were subjected to microscopy. Leucocyte esterase and nitrite positivity were taken into consideration as predictive indicators of UTI. Result: 34% of the samples showed abnormal results on automated urine analyser. Total 28% samples showed positive results for leucocytes, nitrite, protein and RBC’s were sent for urine culture. 5% samples grossly turbid were sent for culture. Conclusion: Automated urinalysis method can be used for the rapid diagnosis of UTI. The algorithm presented in this study will guide the pathologist to decide when culture should be advised after urinalysis. Urine culture is an expensive test for routine use and should not be applied unless the result of nitrite, leukocyte or RBC’s are positive on automated dipstick/ microscopic examination. [Kate M et al NJIRM 2012; 3(5) : 48-52]

The Showa University Journal of Medical Sciences, 2004

Gastrointestinal stromal tumors in the rectum are rare. We present the case of a gastrointestinal... more Gastrointestinal stromal tumors in the rectum are rare. We present the case of a gastrointestinal stromal tumor in the lower rectum. A 60-year-old female was referred to our department for treatment of a perianal lump. On examination by barium enema, colonoscopy, computed tomography and magnetic resonance imaging, she was diagnosed with a gastrointestinal stromal tumor of approximately 3 cm in length between the rectum and the vaginal wall. A perineal approach was considered optimal in this case. Successful local resection with preservation of anal function was indicated by postoperative anal continence and manometry. It is important to consider not only curability but also the patient quality of life in cases of tumors in the lower rectum.

American Journal of Infectious Diseases, 2010

Problem statement: Granulomatous Lobular Mastitis (GLM) or autoimmune mastitis is a rare and beni... more Problem statement: Granulomatous Lobular Mastitis (GLM) or autoimmune mastitis is a rare and benign disease which, except one case reported in an old man, is usually seen during pregnancy or lactation period. This disease was described for the first time by Kessler. Approach: Our case is a 34 year-old woman who has a child with a history of using OCP that primary complaint was swelling, heat and erythema in the right breast. She was diagnosed with mastitis and treated with antibiotics for one month, later on she had experienced stiffness in the breast and a mass was also palpable. The patient was performed surgical drainage and treated with wide spectrum antibiotics being diagnosed with abscess. After one month, a solid mass was palpable so, mammography was performed and the mass was surgically resected with a suspicion of tumor. Results: The pathology report revealed granulomatous mastitis with non caseified granuloma. For Anti-TB treatment was started as medication regime and after 40 days fistula with frequent secretions appeared. Antituberculosis medications stopped and other conditions resulting in none caseified granuloma. In microscopic view granulomatous mastitis along with abscess was reported. Corticosteroids were started and the mass became smaller gradually, the fistula also closed and secretions dried out. Conclusion: Granulomatous Lobular Mastitis is a benign inflammatory breast disease. Cause of disease is still unknown, but some factors have been suggested such as local autoimmune, reaction to the delivery, previous use of contraceptives and infectious causes. The best treatment proposed is corticosteroid therapy in which the mass dwindle and the fistula is closed and secretions dried. The case is now under treatment with corticosteroids and all her symptoms have improved.

Aim: Although urine culture is used as the reference standard to determine presence or absence of... more Aim: Although urine culture is used as the reference standard to determine presence or absence of urinary tract infection (UTI), culture is an expensive and time-consuming method. The objectives of the study were to compare automated dipstick urinalysis with microscopic urinalysis and form an algorithm to reduce time and labour of the pathologist and faster initiation of treatment to the patient. Method: 500 morning urine samples were analysed by using automated dipstick analyser( Cobas u 411) and those samples showing abnormal results were subjected to microscopy. Leucocyte esterase and nitrite positivity were taken into consideration as predictive indicators of UTI. Result: 34% of the samples showed abnormal results on automated urine analyser. Total 28% samples showed positive results for leucocytes, nitrite, protein and RBC’s were sent for urine culture. 5% samples grossly turbid were sent for culture. Conclusion: Automated urinalysis method can be used for the rapid diagnosis o...

Journal of Cancer Research and Therapeutics, 2016

Pure endobronchial neoplasms are a rare entity, and they may present with diverse pathological fi... more Pure endobronchial neoplasms are a rare entity, and they may present with diverse pathological findings. Malignant diseases are more common than benign ones, and they mostly originate from the surface epithelium. Endobronchial tumors usually present with symptoms such as cough, hemoptysis, recurrent pneumonia, wheezing, and chest pain. Flexible bronchoscopy is necessary for diagnosis and evaluation of these endobronchial tumors. Advance bronchoscopy or definitive surgery is the modality of treatment for these tumors based on the presentation. We present a case series of patients suffering from different rare endobronchial tumors and their management along with the review of literature.

ejmanager.com

Although adipocytic tumours are the most common mesenchymal tumours, chondroid variant is an extr... more Although adipocytic tumours are the most common mesenchymal tumours, chondroid variant is an extremely rare entity. Though proximal extremities, limb girdles and head, neck are common sites of occurrence, rarely cases of this unique entity have been reported in oral cavity. Chondroid lipoma due to its complex histology comprised of lipoblast like cells in myxoid and chondroid background, is aptly termed as pseudosarcomatous tumour. Importance of the knowledge of this distinct entity cannot be overestimated since it mimics soft tissue sarcoma. We report one such case of intra oral chondroid lipoma with ossification in young female. [ Kate M et al NJIRM 2012; 3(2) : 182-184]

Journal of Cancer Research and Therapeutics, 2016

Pure endobronchial neoplasms are a rare entity, and they may present with diverse pathological fi... more Pure endobronchial neoplasms are a rare entity, and they may present with diverse pathological findings. Malignant diseases are more common than benign ones, and they mostly originate from the surface epithelium. Endobronchial tumors usually present with symptoms such as cough, hemoptysis, recurrent pneumonia, wheezing, and chest pain. Flexible bronchoscopy is necessary for diagnosis and evaluation of these endobronchial tumors. Advance bronchoscopy or definitive surgery is the modality of treatment for these tumors based on the presentation. We present a case series of patients suffering from different rare endobronchial tumors and their management along with the review of literature.

National Journal of Integrated Research in Medicine, 2012

Aim: Although urine culture is used as the reference standard to determine presence or absence of... more Aim: Although urine culture is used as the reference standard to determine presence or absence of urinary tract infection (UTI), culture is an expensive and time-consuming method. The objectives of the study were to compare automated dipstick urinalysis with microscopic urinalysis and form an algorithm to reduce time and labour of the pathologist and faster initiation of treatment to the patient. Method: 500 morning urine samples were analysed by using automated dipstick analyser( Cobas u 411) and those samples showing abnormal results were subjected to microscopy. Leucocyte esterase and nitrite positivity were taken into consideration as predictive indicators of UTI. Result: 34% of the samples showed abnormal results on automated urine analyser. Total 28% samples showed positive results for leucocytes, nitrite, protein and RBC’s were sent for urine culture. 5% samples grossly turbid were sent for culture. Conclusion: Automated urinalysis method can be used for the rapid diagnosis of UTI. The algorithm presented in this study will guide the pathologist to decide when culture should be advised after urinalysis. Urine culture is an expensive test for routine use and should not be applied unless the result of nitrite, leukocyte or RBC’s are positive on automated dipstick/ microscopic examination. [Kate M et al NJIRM 2012; 3(5) : 48-52]

The Showa University Journal of Medical Sciences, 2004

Gastrointestinal stromal tumors in the rectum are rare. We present the case of a gastrointestinal... more Gastrointestinal stromal tumors in the rectum are rare. We present the case of a gastrointestinal stromal tumor in the lower rectum. A 60-year-old female was referred to our department for treatment of a perianal lump. On examination by barium enema, colonoscopy, computed tomography and magnetic resonance imaging, she was diagnosed with a gastrointestinal stromal tumor of approximately 3 cm in length between the rectum and the vaginal wall. A perineal approach was considered optimal in this case. Successful local resection with preservation of anal function was indicated by postoperative anal continence and manometry. It is important to consider not only curability but also the patient quality of life in cases of tumors in the lower rectum.

American Journal of Infectious Diseases, 2010

Problem statement: Granulomatous Lobular Mastitis (GLM) or autoimmune mastitis is a rare and beni... more Problem statement: Granulomatous Lobular Mastitis (GLM) or autoimmune mastitis is a rare and benign disease which, except one case reported in an old man, is usually seen during pregnancy or lactation period. This disease was described for the first time by Kessler. Approach: Our case is a 34 year-old woman who has a child with a history of using OCP that primary complaint was swelling, heat and erythema in the right breast. She was diagnosed with mastitis and treated with antibiotics for one month, later on she had experienced stiffness in the breast and a mass was also palpable. The patient was performed surgical drainage and treated with wide spectrum antibiotics being diagnosed with abscess. After one month, a solid mass was palpable so, mammography was performed and the mass was surgically resected with a suspicion of tumor. Results: The pathology report revealed granulomatous mastitis with non caseified granuloma. For Anti-TB treatment was started as medication regime and after 40 days fistula with frequent secretions appeared. Antituberculosis medications stopped and other conditions resulting in none caseified granuloma. In microscopic view granulomatous mastitis along with abscess was reported. Corticosteroids were started and the mass became smaller gradually, the fistula also closed and secretions dried out. Conclusion: Granulomatous Lobular Mastitis is a benign inflammatory breast disease. Cause of disease is still unknown, but some factors have been suggested such as local autoimmune, reaction to the delivery, previous use of contraceptives and infectious causes. The best treatment proposed is corticosteroid therapy in which the mass dwindle and the fistula is closed and secretions dried. The case is now under treatment with corticosteroids and all her symptoms have improved.

Aim: Although urine culture is used as the reference standard to determine presence or absence of... more Aim: Although urine culture is used as the reference standard to determine presence or absence of urinary tract infection (UTI), culture is an expensive and time-consuming method. The objectives of the study were to compare automated dipstick urinalysis with microscopic urinalysis and form an algorithm to reduce time and labour of the pathologist and faster initiation of treatment to the patient. Method: 500 morning urine samples were analysed by using automated dipstick analyser( Cobas u 411) and those samples showing abnormal results were subjected to microscopy. Leucocyte esterase and nitrite positivity were taken into consideration as predictive indicators of UTI. Result: 34% of the samples showed abnormal results on automated urine analyser. Total 28% samples showed positive results for leucocytes, nitrite, protein and RBC’s were sent for urine culture. 5% samples grossly turbid were sent for culture. Conclusion: Automated urinalysis method can be used for the rapid diagnosis o...

Journal of Cancer Research and Therapeutics, 2016

Pure endobronchial neoplasms are a rare entity, and they may present with diverse pathological fi... more Pure endobronchial neoplasms are a rare entity, and they may present with diverse pathological findings. Malignant diseases are more common than benign ones, and they mostly originate from the surface epithelium. Endobronchial tumors usually present with symptoms such as cough, hemoptysis, recurrent pneumonia, wheezing, and chest pain. Flexible bronchoscopy is necessary for diagnosis and evaluation of these endobronchial tumors. Advance bronchoscopy or definitive surgery is the modality of treatment for these tumors based on the presentation. We present a case series of patients suffering from different rare endobronchial tumors and their management along with the review of literature.

ejmanager.com

Although adipocytic tumours are the most common mesenchymal tumours, chondroid variant is an extr... more Although adipocytic tumours are the most common mesenchymal tumours, chondroid variant is an extremely rare entity. Though proximal extremities, limb girdles and head, neck are common sites of occurrence, rarely cases of this unique entity have been reported in oral cavity. Chondroid lipoma due to its complex histology comprised of lipoblast like cells in myxoid and chondroid background, is aptly termed as pseudosarcomatous tumour. Importance of the knowledge of this distinct entity cannot be overestimated since it mimics soft tissue sarcoma. We report one such case of intra oral chondroid lipoma with ossification in young female. [ Kate M et al NJIRM 2012; 3(2) : 182-184]