Dr Liman Idris Mohammed | National Hospital Abuja, Nigeria (original) (raw)

Papers by Dr Liman Idris Mohammed

Vol. 41 No. 2 (2023): Tropical Journal of Obstetrics & Gynaecology/Published by Journal Gurus, 2023

Histopathological diseases of the uterine corpus are influenced by several factors including age,... more Histopathological diseases of the uterine corpus are influenced by several factors including age, parity, hormonal and environmental factors. Indeed, majority of neoplastic uterine corporal diseases (notably fibroids, carcinomas and sarcomas) are acknowledged to be manifestations of physiologic and pathologic hormonal influences. Aims: This paper presents a descriptive, analytic study of the neoplastic and non-neoplastic lesions of the uterine corpus from a hitherto poorly reported tertiary hospital of a low and middle-income country (LMIC). Settings and Design: This is a retrospective study of all the uterine corpus samples received in the histopathology department of National Hospital Abuja over an 11-year period from January 1 st 2009, to December 31 st 2019. Methods and Material: Data on all uterine corpus samples were retrieved from departmental electronic registers. Further clinical information was obtained from the health records of the hospital where necessary. The neoplastic lesions were classified using the 5th edition of the World Health Organization (WHO) Classification of Tumours. Statistical analysis used: The data obtained were collated and analyzed using the Statistical Package for Social Sciences (SPSS), version 20. The data were presented in proportion, frequency tables and figures. Results: Of the 3311 uterine corpus samples analyzed, 60.2% were non-neoplastic lesions whilst the rest (39.8%) were neoplastic of which 94% of the neoplastic lesions were benign whilst 6% were malignant. Uterine leiomyomata constituted 87.2% (N=1326) of all neoplastic samples. Endometrial carcinoma represented the commonest neoplastic malignant lesion accounting for 65.9%, of which endometrioid histology was the predominant subtype with fewer proportions of carcinosarcoma, serous carcinoma and undifferentiated carcinoma. Conclusions: Leiomyoma is the commonest benign neoplastic uterine corporal lesion whilst endometrial adenocarcinoma is the predominant malignant lesion.

Vol. 41 No. 2 (2023): Tropical Journal of Obstetrics & Gynaecology/Published by Journal Gurus, 2023

Background and setting: Maternal mortality is a catastrophe associated with pregnancy resulting i... more Background and setting: Maternal mortality is a catastrophe associated with pregnancy resulting in the loss of life of a woman; and is a global indicator of the obstetrics performance of a centre. This study reports the maternal mortality in National Hospital Abuja, a 400-bed tertiary public hospital located in the cosmopolitan city of Abuja the capital of Nigeria, a low resource country. Aims: To determine the ratio, aetiology and cause of Death, presentation, and management of maternal deaths in National Hospital Abuja (NHA), North Central Nigeria. Materials and method: All patients with 'pregnancy associated mortality' (54 in number) in NHA for the period of twenty years were retrospectively reviewed against the total live birth of 29,389 in the same period. Results: During the twenty-year period the maternal mortality ratio was found to be 184 per 100,000 Live Births. The mean age of the patients was 31.46 years ± 5.7 with mean gestational age of 30.34 weeks ± 9.6. Most (57.4%) of the maternal deaths were in the age range of 30-39 years and 87% were unbooked patients. Majority of the deaths (77.8%) were in the third trimester and most of the patients were of low parity. The commonest underlying cause of death was pre-eclampsia/eclampsia. Conclusion: Maternal mortality ratio from our facility is low when compared with national data. These deaths were found mostly among unregistered patients and were commonly caused by pre-eclampsia/eclampsia with haemorrhage coming closely second. The post-mortem examination rate for maternal mortality is low. Strengthening the secondary health care facility in the zone as well as early referral of cases could help curtail maternal death.

Middle East Fertility Society Journal

Background The chance of achieving a successful pregnancy through in vitro fertilization and embr... more Background The chance of achieving a successful pregnancy through in vitro fertilization and embryo transfer (IVF-ET) is limited despite recent scientific advances in this field due to several factors that are known to affect the outcome. There are studies linking the presence of bacteria in the male genital tract to poor semen parameters and IVF-ET outcomes. Results are, however, contradictory. The finding of confirmed genital tract infection warrants treatment, especially when dealing with infertile couples, but treating asymptomatic bacteriospermia is controversial. This study assessed the prevalence and effects of seminal fluid bacterial isolates on semen quality and rates of fertilization and biochemical and clinical pregnancies in IVF-ET. Methodology This is an analytical cross-sectional study conducted at the IVF Center of National Hospital Abuja, Nigeria. Due to the low turnout of clients, we enrolled all consecutive consenting eligible male partners of women undergoing the ...

Middle East Fertility Society Journal (2023) 28:8 , 2023

Nigerian Postgraduate Medical Journal, 2021

Uterine malformations are often asymptomatic but can be associated with a wide range of reproduct... more Uterine malformations are often asymptomatic but can be associated with a wide range of reproductive problems. We report a case of uterine fusion defect diagnosed intra-operatively in a 20-year-old primigravida who had elective caesarean section at term on account of breech presentation at term. Intraoperative findings included a cone-shaped uterus with narrowed fundus and the appendages emerging at the fundus and lower uterine segment on the right and left respectively. This is a rare fusion defect and makes a case for review of the existing uterine malformation classification systems, to make it all encompassing.

Sahel Medical Journal, 2020

Introduction: In Nigeria, cancer of the cervix is known to be the second commonest malignancy amo... more Introduction: In Nigeria, cancer of the cervix is known to be the second commonest malignancy among females. In developed countries, there has been a paradigm shift attributed to effective cervical cancer screening predominantly using the Papanicolaou (Pap) smear. This screening tool is highly sensitive and specific; having a commendable positive predictive value as well as relatively cheap and effective means of screening cervical cancer for early detection. Objectives: The aim of this study is to assess the perception of Pap smear among medical students in College of Health Sciences, Usmanu Danfodiyo University, Sokoto (CHS-UDUS) in order to be able to recommend ways for improving acceptability, usage, and dissemination of information of the screening tool (Pap smear). Materials and Methods: The study utilized a cross-sectional study design. Preclinical students of CHS-UDUS were selected using random sampling technique. Pretested semi-structured, self-administered questionnaires were administered on the students. Quantitative variables were analyzed and presented using measures of central tendency [mean and median] and measures of dispersion (standard deviation), while Chi-square test was used in bivariate analyses, to determine the statistical association between the categorical groups, with a P < 0.05 considered as statistically significant. Results: Preclinical medical students in UDUS were found to have high awareness of cervical cancer-screening (82%) which made them positively disposed toward the screening tool. Most of them (75.6%) believe that Pap smear is effective in detecting cervical cancer. Majority of respondents obtained their information from routine lectures (81%) as against mass media (7%) and other extraneous source. However 42.8% were unaware of Pap smear screening services availability in their institution. Conclusion: The level of awareness about cervical cancer screening is high among the study population. Future studies should concentrate on utilization of this service in later life of young students.

BMC Infectious Diseases, 2013

Background There are no accurate data regarding the real prevalence of Chlamydia trachomatis infe... more Background There are no accurate data regarding the real prevalence of Chlamydia trachomatis infection in Spain. Our aim was to determine the prevalence of C. trachomatis infections and the risk factors for acquiring them among 1,048 young (15–24 years old) inhabitants of Laviana. Methods The study was completed in the period between 1st November 2010 and 31st December 2011. We conducted a capture strategy in the whole population, instead of only in a sample group, with a capture conducted in schools, in the local health centre, by post and by phone as a last resort. The design was based on the model used by Shafer to increase screening rates. C. trachomatis was identified by RT-PCR in urine samples. Results A total of 487 sexually active people underwent the test, which implies a response rate of 59.8% of the sexually active people (target population). The prevalence was 4.1% (CI 95%: 3.1-5.8): women: 4% ( CI 95%; 2.8-6.4) and men: 4.3% (CI 95%: 2.9-7.2). The circulating genotype w...

Sahel Medical Journal, 2017

Introduction: Breast cancer is a major global public health problem accounting for massive morbid... more Introduction: Breast cancer is a major global public health problem accounting for massive morbidity and significant mortality worldwide. Factors contributing to breast cancer mortality have been a topic of intense research and discussion in the scientific world. There is, however, a dearth of information on the incidence of breast cancer mortality in most resource-poor countries including Nigeria. Available data from most African workers on breast cancer focused on incidence, risk factors, and complications rather than mortality. The unique ethnic heterogeneity of Abuja and its peculiar lifestyle (as compared to other Nigerian cities) provides added impetus for assessing breast cancer mortality in one of the Nigeria's fastest growing cities. This study is carried out in a 400-bedded public tertiary hospital in Abuja, the capital of Nigeria. Materials and Methods: A retrospective review of all breast samples in the department of histopathology over a decade is performed supported by clinical information from the medical record archives. Results: Of 2292 breast samples received in the department, 35.3% (n = 810) are malignant out of which 10.6% (n = 86) died. Breast cancer incidence increased from 29 in 2005 to 141 by 2013 while mortality declined from 11 to 9 over the same period. A crude fatality rate of 3.7% is observed. The ages of the decedents ranged from 20 to 90 years with a mean of 43.5 years. Infiltrative ductal carcinoma accounts for the largest mortality with 87.4%. Conclusion: Breast cancer is an important cause of mortality among females and efforts at early detection and treatment should be intensified.

Case report, 2021

Amin et al. Perception of cervical cancer and its cytological screening among medical students in Nigeria, 2020

Introduction: In Nigeria, cancer of the cervix is known to be the second commonest malignancy amo... more Introduction: In Nigeria, cancer of the cervix is known to be the second commonest malignancy among females. In developed countries, there has been a paradigm shift attributed to effective cervical cancer screening predominantly using the Papanicolaou (Pap) smear. This screening tool is highly sensitive and specific; having a commendable positive predictive value as well as relatively cheap and effective means of screening cervical cancer for early detection. Aim: The aim of this study is to assess the perception of Pap smear among medical students in College of Health Sciences, Usmanu Danfodiyo University, Sokoto (CHS‑UDUS) in order to be able to recommend ways for improving acceptability, usage, and dissemination of information of the screening tool (Pap smear).
Methods: The study utilized a cross‑sectional study design. Preclinical students of CHS‑UDUS were selected using a random sampling technique. Pretested semi‑structured, self‑administered questionnaires were administered on the students. Quantitative variables were analyzed and presented using measures of central tendency [mean and median] and measures of dispersion (standard deviation), while the Chi‑square test was used in bivariate analyses, to determine the statistical association between the categorical groups, with a P < 0.05 considered as statistically significant. Results: Preclinical medical students in UDUS were found to have a high awareness of cervical cancer screening (82%) which made them positively disposed toward the screening tool. Most of them (75.6%) believe that Pap smear is effective in detecting cervical cancer. Majority of respondents obtained their information from routine lectures (81%)
against mass media (7%) and other extraneous sources. 42.8% are however unaware of Pap smear screening services available in their institution. Conclusion: An intense and focused lecture curriculum to medical students on cancer screening might help fill the knowledge gap for these students and possibly aid dissemination of information on the screening program.
Keywords: Cervical cancer screening, medical students, Nigeria, perception

In Nigeria, cancer of the cervix is known to be the second commonest malignancy among females. In... more In Nigeria, cancer of the cervix is known to be the second commonest malignancy among females. In developed countries, there has been a paradigm shift attributed to effective cervical cancer screening predominantly using the Papanicolaou (Pap) smear. This screening tool is highly sensitive and specific; having a commendable positive predictive value as well as relatively cheap and effective means of screening cervical cancer for early detection. Objectives: The aim of this study is to assess the perception of Pap smear among medical students in College of Health Sciences, Usmanu Danfodiyo University, Sokoto (CHS-UDUS) in order to be able to recommend ways for improving acceptability, usage, and dissemination of information of the screening tool (Pap smear). Materials and Methods: The study utilized a cross-sectional study design. Preclinical students of CHS-UDUS were selected using random sampling technique. Pretested semi-structured, self-administered questionnaires were administered on the students. Quantitative variables were analyzed and presented using measures of central tendency [mean and median] and measures of dispersion (standard deviation), while Chi-square test was used in bivariate analyses, to determine the statistical association between the categorical groups, with a P < 0.05 considered as statistically significant. Results: Preclinical medical students in UDUS were found to have high awareness of cervical cancer-screening (82%) which made them positively disposed toward the screening tool. Most of them (75.6%) believe that Pap smear is effective in detecting cervical cancer. Majority of respondents obtained their information from routine lectures (81%) as against mass media (7%) and other extraneous source. However 42.8% were unaware of Pap smear screening services availability in their institution. Conclusion: The level of awareness about cervical cancer screening is high among the study population. Future studies should concentrate on utilization of this service in later life of young students.

Archives of Medicine and Health Review, 2018

Introduction: Chlamydia trachomatis infection is one of the commonest sexually transmitted infect... more Introduction: Chlamydia trachomatis infection is one of the commonest sexually transmitted infections that cause pelvic inflammatory disease. While more than 50% of women with Chlamydia cervicitis are asymptomatic, the long-term sequelae on the reproductive potential of the population are enormous. Chlamydia infection can be effectively treated with antibiotics but there is no screening programme to identify infected individuals in Nigeria. Materials and Methods: A descriptive cross-sectional study to determine the prevalence and pattern of Chlamydia trachomatis infection and its relationship with infertility among 420 women of reproductive age seen at the Department of Obstetrics and Gynaecology, National Hospital, Abuja, Nigeria. Sociodemographic information of the women was obtained after which their endocervical specimens were taken and tested for the presence of Chlamydia trachomatis using the Onsite Chlamydia Antigen Rapid Test. Results were analyzed using SPSS version 21.0. Student's t-test and Chi-square test were used as appropriate. P value < 0.05 at 95% Confidence Interval was regarded as statistically significant. Results: The prevalence of genital Chlamydia trachomatis was 11.4% with the highest rate (12.9%) among women between the ages of 30 to 39 years. Although higher genital Chlamydia trachomatis infections exist among women with the history of infertility, multiple sex partners, early coitarche and married marital status, these findings were not statistically significant. Conclusion: Community health education and development of routine screening and treatment of genital Chlamydial infection is important to reduce the enormous burden of this disease, and is hereby recommended.

ABSTRACT INTRODUCTION; Breast cancer is a major global public health problem accounting for massi... more ABSTRACT
INTRODUCTION; Breast cancer is a major global public health problem accounting for massive morbidity and significant mortality worldwide. Factors contributing to breast-cancer mortality have been a topic of intense research and discussion in the scientific world. SETTING; This study is carried out in a 400-bedded tertiary hospital in Abuja, capital of Nigeria. MATERIALS AND METHODS; A retrospective review of all breast samples in the department of Histopathology over a decade is performed supported by clinical information including outcome from the Medical Record archives. RESULTS: Of 2292 breast samples received in the department, 35.3% (n=810) are malignant out of which 10.6% (n=86) died. Breast cancer incidence increased from 29 in 2005 to 141 by 2013 while mortality declined from eleven (11) to nine (9) over the same period. A crude fatality rate of 3.7% is observed. The ages of the decedents ranged from 20 to 90 years with a mean of 43.5 years. Infiltrative ductal carcinoma accounts for the largest mortality with 87.4%. CONCLUSION: Breast cancer is an important cause of mortality among females and efforts at early detection and treatment should be intensified.

INTRODUCTION; Breast cancer is a major global public health problem accounting for massive morbid... more INTRODUCTION; Breast cancer is a major global public health problem accounting for massive morbidity and significant mortality worldwide. Factors contributing to breast-cancer mortality have been a topic of intense research and discussion in the scientific world. SETTING; This study is carried out in a 400-bedded tertiary hospital in Abuja, capital of Nigeria. MATERIALS AND METHODS; A retrospective review of all breast samples in the department of Histopathology over a decade is performed supported by clinical information from the Medical Record archives. RESULTS: Of 2292 breast samples received in the department, 35.3% (n=810) are malignant out of which 10.6% (n=86) died. Breast cancer incidence increased from 29 in 2005 to 141 by 2013 while mortality declined from eleven (11) to nine (9) over the same period. A crude fatality rate of 3.7% is observed. The ages of the decedents ranged from 20 to 90 years with a mean of 43.5 years. Infiltrative ductal carcinoma accounts for the larg...

INTRODUCTION; Diseases of the cervix are important cause of morbidity and mortality globally and ... more INTRODUCTION; Diseases of the cervix are important cause of morbidity and mortality globally and particularly serious in developing countries. OBJECTIVES; To carry out a retrospective review of the surgical cervical lesions in National Hospital Abuja and compare the results with other similar studies in Nigeria and abroad. MATERIALS AND METHODS; All cervical surgical samples received in the Department of Histopathology from 1st January 2004 to 31st December 2013 were accessed and the slides retrieved and reviewed. The results are analyzed using simple statistical methods. RESULTS; Of the 560 cervical samples received in the department 46% are neoplastic composed of 23% each of malignant and benign tumours respectively. Squamous cell carcinoma is the commonest malignant tumour while cervical intraepithelial neoplasia is the commonest benign lesions. CONCLUSION. The large number of CIN underscores the need for an effective screening program.

INTRODUCTION; It is estimated that worldwide cervical cancer accounts for death of 231,000 women ... more INTRODUCTION; It is estimated that worldwide cervical cancer accounts for death of 231,000 women annually and over 80% of these are said to be in the developing countries.1 This sordid fact is observed in spite of the globally acknowledged effectiveness of cervical cancer screening methods in detecting and indeed eradicating the disease. SETTING; National Hospital Abuja is a tertiary hospital located in the cosmopolitan city of Abuja, capital of Nigeria. It offers regular cervical conventional cytology screening services to Abuja metropolis and surrounding environment. MATERIAL AND METHOD; A retrospective review of all cervical cytology samples received in the department of Histopathology of the NHA from 1st January 2004 to 31st December 2013. Slides were reviewed and diagnosis made according to the Bethesda 2001 classification of cervical cytology. Results are analyzed using simple Microsoft Excel 2011 statistical methods. RESULT; Of 5667 samples reviewed 14.8% (n=816) showed abnormal cellular changes. Approximately 49.4%, 24.4%, 20.7% and 5% of the abnormal smears constituted the LSIL, HSIL, ASCUS and invasive categories respectively. Majority of the women (72%) and most of the abnormal smears belong to the age group 30 to 49 years. CONCLUSION; Abnormal cervical smears are considerably high and age group 30 to 49 years are at increased risk. Intense and sustained cervical cancer screening programme needs to be embarked upon in Nigeria.

Vol. 41 No. 2 (2023): Tropical Journal of Obstetrics & Gynaecology/Published by Journal Gurus, 2023

Middle East Fertility Society Journal

Middle East Fertility Society Journal (2023) 28:8 , 2023

Nigerian Postgraduate Medical Journal, 2021

Sahel Medical Journal, 2020

BMC Infectious Diseases, 2013

Sahel Medical Journal, 2017

Case report, 2021

Amin et al. Perception of cervical cancer and its cytological screening among medical students in Nigeria, 2020

Introduction: In Nigeria, cancer of the cervix is known to be the second commonest malignancy amo... more Introduction: In Nigeria, cancer of the cervix is known to be the second commonest malignancy among females. In developed countries, there has been a paradigm shift attributed to effective cervical cancer screening predominantly using the Papanicolaou (Pap) smear. This screening tool is highly sensitive and specific; having a commendable positive predictive value as well as relatively cheap and effective means of screening cervical cancer for early detection. Aim: The aim of this study is to assess the perception of Pap smear among medical students in College of Health Sciences, Usmanu Danfodiyo University, Sokoto (CHS‑UDUS) in order to be able to recommend ways for improving acceptability, usage, and dissemination of information of the screening tool (Pap smear).
Methods: The study utilized a cross‑sectional study design. Preclinical students of CHS‑UDUS were selected using a random sampling technique. Pretested semi‑structured, self‑administered questionnaires were administered on the students. Quantitative variables were analyzed and presented using measures of central tendency [mean and median] and measures of dispersion (standard deviation), while the Chi‑square test was used in bivariate analyses, to determine the statistical association between the categorical groups, with a P < 0.05 considered as statistically significant. Results: Preclinical medical students in UDUS were found to have a high awareness of cervical cancer screening (82%) which made them positively disposed toward the screening tool. Most of them (75.6%) believe that Pap smear is effective in detecting cervical cancer. Majority of respondents obtained their information from routine lectures (81%)
against mass media (7%) and other extraneous sources. 42.8% are however unaware of Pap smear screening services available in their institution. Conclusion: An intense and focused lecture curriculum to medical students on cancer screening might help fill the knowledge gap for these students and possibly aid dissemination of information on the screening program.
Keywords: Cervical cancer screening, medical students, Nigeria, perception

Archives of Medicine and Health Review, 2018