Discover 3Rs innovations from the NC3Rs (original) (raw)

Major 3Rs advances in preclinical sciences and safety assessment across the bioscience sector require innovation to deliver readily available and easily deployed models and tools that are more predictive and cost-effective than current animal models.

Discover 3Rs innovations

Image of a 3D rendering of a cancer cell Reducing animal use in the development of cell and gene therapies An advanced imaging system developed through CRACK IT Challenges aims to improve in vivo data quality in preclinical studies. 16 October 2025

Challenge highlight: Tat-Fit Fluid Pharma Ltd have developed a tasteless tamoxifen formulation to improve tamoxifen administration to rodents for cre-recombination studies. Find out more on our Challenge page.

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Microbiology CRACK IT Challenges Apply for funding to develop 3Rs technologies and approaches that improve business processes or lead to marketable products.

Decorative image showing lab equipment Technology Partnering Find collaborators to accelerate the commercial readiness of 3Rs technologies and approaches.

Lung chip close up on microscope 3Rs Products Learn more about the scientific, commercial and 3Rs benefits of marketable technologies developed through CRACK IT Challenges.