Bishop Thomas Paprocki | University of Notre Dame (original) (raw)
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Papers by Bishop Thomas Paprocki
The Jurist: Studies in Church Law and Ministry
S ince being appointed bishop of Spring eld, Illinois in 2010, I have been asked many times about... more S ince being appointed bishop of Spring eld, Illinois in 2010, I have been asked many times about the matter of Holy Communion for Sen. Richard Durbin, whose home is in Spring eld. In April 2004, Sen. Durbin's pastor, Msgr. Kevin Vann (now Bishop Kevin Vann of Orange, California), said he would "be reticent" to give Sen. Durbin Holy Communion because his pro-abortion position placed him outside of unity with the Church's teachings on life. My predecessor, now Archbishop George Lucas of Omaha, said that he supported Msgr. Vann's decision. I have maintained that position. This determination is based on Canon 915 of the Catholic Church's Code of Canon Law, which states that those "who obstinately persist in manifest grave sin are not to be admitted to Holy Communion." In our 2004 statement on "Catholics in Political Life," the bishops of the United States said, Failing to protect the lives of innocent and defenseless members of the human race is to sin against justice. Those who formulate law therefore have an obligation in conscience to work toward correcting morally defective laws, lest they be guilty of cooperating in evil and in sinning against the common good. Because his voting record in support of abortion over many years constitutes "obstinate persistence in manifest grave sin," the determination continues that Sen. Durbin is not to be admitted to Holy Communion until he repents of this sin. This provision is intended not to punish, but to bring about a change of heart. Sen. Durbin was pro-life when he started out in politics in central Illinois. The denial of Support FIRST THINGS by turning your adblocker o or by making a donation. Thanks!
The Jurist: Studies in Church Law and Ministry
The Jurist: Studies in Church Law and Ministry
Studia canonica: Revue canadienne de droit canonique = A Canadian Canon Law Review, 2019
Journal of Catholic Legal Studies, 2017
Journal of Catholic Legal Studies, 2017
Cohesin is a multi-protein complex that tethers sister chromatids during mitosis and mediates DNA... more Cohesin is a multi-protein complex that tethers sister chromatids during mitosis and mediates DNA repair, genome compartmentalisation and regulation of gene expression. Cohesin subunits frequently acquire cancer loss-of-function alterations and act as tumour suppressors in several tumour types. This has led to increased interest in cohesin as potential target in anti-cancer therapy. Here we show that the loss-of-function of STAG2, a core component of cohesin and an emerging tumour suppressor, leads to synthetic dependency of mutated cancer cells on its paralog STAG1. STAG1 and STAG2 share high sequence identity, encode mutually exclusive cohesin subunits and retain partially overlapping functions. We inhibited STAG1 and STAG2 in several cancer cell lines where the two genes have variable mutation and copy number status. In all cases, we observed that the simultaneous blocking of STAG1 and STAG2 significantly reduces cell proliferation. We further confirmed the synthetic lethal interaction developing a vector-free CRISPR system to induce STAG1/STAG2 double gene knockout. We provide strong evidence that STAG1 is a promising therapeutic target in cancers with inactivating alterations of STAG2.
The Catholic lawyer, 2017
Notre Dame Journal of Law, Ethics & Public Policy, 2014
The National Catholic Bioethics Quarterly
The effects of the novel coronavirus have raised questions about the extent to which social shutd... more The effects of the novel coronavirus have raised questions about the extent to which social shutdowns are appropriate. We have a responsibility to protect the lives of others and an obligation to maintain our lives and health when possible, but there are circumstances when it is just to decline certain measures that are considered extraordinary to the situation. Measures taken to protect life must be proportionate. That is, they must offer a reasonable hope of benefit and not impose excessive burdens on individuals, families, or the community. The measures enacted during the COVID-19 pandemic are not proportionate. Restrictions on family and religious activities are disproportionate to the benefit they provide, particularly to the extent that they obstruct the Church in its duty to tend to the health of souls and salvation of its members
Ethics & Medics
The effects of the novel coronavirus have raised questions about the extent to which social shutd... more The effects of the novel coronavirus have raised questions about the extent to which social shutdowns are appropriate. We have a responsibility to protect the lives of others and an obligation to maintain our lives and health when possible, but there are circumstances when it is just to decline certain measures that are considered extraordinary to the situation. Measures taken to protect life must be proportionate. That is, they must offer a reasonable hope of benefit and not impose excessive burdens on individuals, families, or the community. The measures enacted during the COVID-19 pandemic are not proportionate. Restrictions on family and religious activities are disproportionate to the benefit they provide, particularly to the extent that they obstruct the Church in its duty to tend to the health of souls and salvation of its members.
The Jurist: Studies in Church Law and Ministry, 2015
Loyola University Chicago Law Journal, 2007
A recent Google search on the Internet for the name "Matthew Shepard" produced 11,900,000 results... more A recent Google search on the Internet for the name "Matthew Shepard" produced 11,900,000 results. Matthew Shepard was a 21year-old college student who was savagely beaten to death in 1998 in Wyoming. His murder has been called a hate crime because Shepard was gay. A similar search on the Internet for the name "Mary Stachowicz" yielded 26,800 results. In 2002, Mary Stachowicz was also brutally murdered, but the circumstances were quite different. Mary, the gentle, devout, 51-year-old Catholic mother of four, urged her coworker, Nicholas Gutierrez, 19, to change his gay lifestyle. Infuriated by this, as he later told police, he allegedly beat, stabbed, and strangled her to death and then stuffed her mangled body into a crawl space in his apartment, which was located above a Chicago funeral home where they both worked. I know about Mary Stachowicz, not from the Internet, but personally, because Mary was my secretary at the parish where I was pastor before I was named a Bishop. She worked part-time at the funeral home and part-time at the parish. One afternoon, she did not show up at her normal starting time. This was unusual because she was always on time. A call to the funeral home disclosed that her car was still in the parking lot, her purse, with her car keys, was still at her desk, but there was no sign of Mary. As Mary's family and friends prayed and worried about her disappearance, Gutierrez prayed with them. Three days later, her mutilated body was discovered in a crawl space in his apartment. Both murders were senseless and brutal, and I condemn them both unequivocally. However, the fact that there are over eleven-and-a-half million more Internet stories about Matthew Shepard than Mary Stachowicz indicates where popular sentiment lies today on the question
The Jurist: Studies in Church Law and Ministry
S ince being appointed bishop of Spring eld, Illinois in 2010, I have been asked many times about... more S ince being appointed bishop of Spring eld, Illinois in 2010, I have been asked many times about the matter of Holy Communion for Sen. Richard Durbin, whose home is in Spring eld. In April 2004, Sen. Durbin's pastor, Msgr. Kevin Vann (now Bishop Kevin Vann of Orange, California), said he would "be reticent" to give Sen. Durbin Holy Communion because his pro-abortion position placed him outside of unity with the Church's teachings on life. My predecessor, now Archbishop George Lucas of Omaha, said that he supported Msgr. Vann's decision. I have maintained that position. This determination is based on Canon 915 of the Catholic Church's Code of Canon Law, which states that those "who obstinately persist in manifest grave sin are not to be admitted to Holy Communion." In our 2004 statement on "Catholics in Political Life," the bishops of the United States said, Failing to protect the lives of innocent and defenseless members of the human race is to sin against justice. Those who formulate law therefore have an obligation in conscience to work toward correcting morally defective laws, lest they be guilty of cooperating in evil and in sinning against the common good. Because his voting record in support of abortion over many years constitutes "obstinate persistence in manifest grave sin," the determination continues that Sen. Durbin is not to be admitted to Holy Communion until he repents of this sin. This provision is intended not to punish, but to bring about a change of heart. Sen. Durbin was pro-life when he started out in politics in central Illinois. The denial of Support FIRST THINGS by turning your adblocker o or by making a donation. Thanks!
The Jurist: Studies in Church Law and Ministry
The Jurist: Studies in Church Law and Ministry
Studia canonica: Revue canadienne de droit canonique = A Canadian Canon Law Review, 2019
Journal of Catholic Legal Studies, 2017
Journal of Catholic Legal Studies, 2017
Cohesin is a multi-protein complex that tethers sister chromatids during mitosis and mediates DNA... more Cohesin is a multi-protein complex that tethers sister chromatids during mitosis and mediates DNA repair, genome compartmentalisation and regulation of gene expression. Cohesin subunits frequently acquire cancer loss-of-function alterations and act as tumour suppressors in several tumour types. This has led to increased interest in cohesin as potential target in anti-cancer therapy. Here we show that the loss-of-function of STAG2, a core component of cohesin and an emerging tumour suppressor, leads to synthetic dependency of mutated cancer cells on its paralog STAG1. STAG1 and STAG2 share high sequence identity, encode mutually exclusive cohesin subunits and retain partially overlapping functions. We inhibited STAG1 and STAG2 in several cancer cell lines where the two genes have variable mutation and copy number status. In all cases, we observed that the simultaneous blocking of STAG1 and STAG2 significantly reduces cell proliferation. We further confirmed the synthetic lethal interaction developing a vector-free CRISPR system to induce STAG1/STAG2 double gene knockout. We provide strong evidence that STAG1 is a promising therapeutic target in cancers with inactivating alterations of STAG2.
The Catholic lawyer, 2017
Notre Dame Journal of Law, Ethics & Public Policy, 2014
The National Catholic Bioethics Quarterly
The effects of the novel coronavirus have raised questions about the extent to which social shutd... more The effects of the novel coronavirus have raised questions about the extent to which social shutdowns are appropriate. We have a responsibility to protect the lives of others and an obligation to maintain our lives and health when possible, but there are circumstances when it is just to decline certain measures that are considered extraordinary to the situation. Measures taken to protect life must be proportionate. That is, they must offer a reasonable hope of benefit and not impose excessive burdens on individuals, families, or the community. The measures enacted during the COVID-19 pandemic are not proportionate. Restrictions on family and religious activities are disproportionate to the benefit they provide, particularly to the extent that they obstruct the Church in its duty to tend to the health of souls and salvation of its members
Ethics & Medics
The effects of the novel coronavirus have raised questions about the extent to which social shutd... more The effects of the novel coronavirus have raised questions about the extent to which social shutdowns are appropriate. We have a responsibility to protect the lives of others and an obligation to maintain our lives and health when possible, but there are circumstances when it is just to decline certain measures that are considered extraordinary to the situation. Measures taken to protect life must be proportionate. That is, they must offer a reasonable hope of benefit and not impose excessive burdens on individuals, families, or the community. The measures enacted during the COVID-19 pandemic are not proportionate. Restrictions on family and religious activities are disproportionate to the benefit they provide, particularly to the extent that they obstruct the Church in its duty to tend to the health of souls and salvation of its members.
The Jurist: Studies in Church Law and Ministry, 2015
Loyola University Chicago Law Journal, 2007
A recent Google search on the Internet for the name "Matthew Shepard" produced 11,900,000 results... more A recent Google search on the Internet for the name "Matthew Shepard" produced 11,900,000 results. Matthew Shepard was a 21year-old college student who was savagely beaten to death in 1998 in Wyoming. His murder has been called a hate crime because Shepard was gay. A similar search on the Internet for the name "Mary Stachowicz" yielded 26,800 results. In 2002, Mary Stachowicz was also brutally murdered, but the circumstances were quite different. Mary, the gentle, devout, 51-year-old Catholic mother of four, urged her coworker, Nicholas Gutierrez, 19, to change his gay lifestyle. Infuriated by this, as he later told police, he allegedly beat, stabbed, and strangled her to death and then stuffed her mangled body into a crawl space in his apartment, which was located above a Chicago funeral home where they both worked. I know about Mary Stachowicz, not from the Internet, but personally, because Mary was my secretary at the parish where I was pastor before I was named a Bishop. She worked part-time at the funeral home and part-time at the parish. One afternoon, she did not show up at her normal starting time. This was unusual because she was always on time. A call to the funeral home disclosed that her car was still in the parking lot, her purse, with her car keys, was still at her desk, but there was no sign of Mary. As Mary's family and friends prayed and worried about her disappearance, Gutierrez prayed with them. Three days later, her mutilated body was discovered in a crawl space in his apartment. Both murders were senseless and brutal, and I condemn them both unequivocally. However, the fact that there are over eleven-and-a-half million more Internet stories about Matthew Shepard than Mary Stachowicz indicates where popular sentiment lies today on the question