Lynn Rochester | Newcastle University (original) (raw)

Papers by Lynn Rochester

Research paper thumbnail of The Role of Movement Analysis in Diagnosing and Monitoring Neurodegenerative Conditions: Insights from Gait and Postural Control

Brain Sciences

Quantifying gait and postural control adds valuable information that aids in understanding neurol... more Quantifying gait and postural control adds valuable information that aids in understanding neurological conditions where motor symptoms predominate and cause considerable functional impairment. Disease-specific clinical scales exist; however, they are often susceptible to subjectivity, and can lack sensitivity when identifying subtle gait and postural impairments in prodromal cohorts and longitudinally to document disease progression. Numerous devices are available to objectively quantify a range of measurement outcomes pertaining to gait and postural control; however, efforts are required to standardise and harmonise approaches that are specific to the neurological condition and clinical assessment. Tools are urgently needed that address a number of unmet needs in neurological practice. Namely, these include timely and accurate diagnosis; disease stratification; risk prediction; tracking disease progression; and decision making for intervention optimisation and maximising therapeut...

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Research paper thumbnail of Free-living monitoring of Parkinson’s disease: lessons from the field.

Wearable technology comprises miniaturized sensors (eg, accelerometers) worn on the body and/or p... more Wearable technology comprises miniaturized sensors (eg, accelerometers) worn on the body and/or paired with mobile devices (eg, smart phones) allowing continuous patient monitoring in unsupervised, habitual environments (termed free-living). Wearable technologies are revolutionizing approaches to health care as a result of their utility, accessibility, and affordability. They are positioned to transform Parkinson's disease (PD) management through the provision of individualized, comprehensive, and representative data. This is particularly relevant in PD where symptoms are often triggered by task and free-living environmental challenges that cannot be replicated with sufficient veracity elsewhere. This review concerns use of wearable technology in free-living environments for people with PD. It outlines the potential advantages of wearable technologies and evidence for these to accurately detect and measure clinically relevant features including motor symptoms, falls risk, freezing of gait, gait, functional mobility, and physical activity. Technological limitations and challenges are highlighted, and advances concerning broader aspects are discussed. Recommendations to overcome key challenges are made. To date there is no fully validated system to monitor clinical features or activities in free-living environments. Robust accuracy and validity metrics for some features have been reported, and wearable technology may be used in these cases with a degree of confidence. Utility and acceptability appears reasonable, although testing has largely been informal. Key recommendations include adopting a multidisciplinary approach for standardizing definitions, protocols, and outcomes. Robust validation of developed algorithms and sensor-based metrics is required along with testing of utility. These advances are required before widespread clinical adoption of wearable technology can be realized. © 2016 International Parkinson and Movement Disorder Society.© 2016 International Parkinson and Movement Disorder Society.

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Research paper thumbnail of Free-living gait characteristics in ageing and Parkinson's disease: impact of environment and ambulatory bout length.

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Research paper thumbnail of Validation of an accelerometer to quantify a comprehensive battery of gait characteristics in healthy older adults and Parkinson's disease: toward clinical and at home use

IEEE journal of biomedical and health informatics, Jan 2, 2015

Measurement of gait is becoming important as a tool to identify disease and disease progression, ... more Measurement of gait is becoming important as a tool to identify disease and disease progression, yet to date its application is limited largely to specialist centres. Wearable devices enables gait to be measured in naturalistic environments however questions remain regarding validity. Previous research suggests that when compared with a laboratory reference, measurement accuracy is acceptable for mean but not variability or asymmetry gait characteristics. Some fundamental reasons for this have been presented (e.g. synchronisation, different sampling frequencies) but to date this has not been systematically examined. The aims of this study were to: (i) quantify a comprehensive range of gait characteristics measured using a single tri-axial accelerometer-based monitor, (ii) examine outcomes and monitor performance in measuring gait in older adults and those with Parkinson's disease (PD) and (iii) carry out a detailed comparison with those derived from an instrumented walkway to ac...

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Research paper thumbnail of The Effect of Environment and Task on Gait Parameters After Stroke: A Randomized Comparison of Measurement Conditions

Archives of Physical Medicine and Rehabilitation, 2006

Lord SE, Rochester L, Weatherall M, McPherson KM, McNaughton HK. The effect of environment and ta... more Lord SE, Rochester L, Weatherall M, McPherson KM, McNaughton HK. The effect of environment and task on gait parameters after stroke: a randomized comparison of measurement conditions.

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Research paper thumbnail of Community ambulation after stroke: how important and obtainable is it and what measures appear predictive? 1 1 No commercial party having a direct financial interest in the results of the research supporting this article has or will confer a benefit on the author(s) or on any organization with wh...

Archives of Physical Medicine and Rehabilitation, 2004

Lord SE, McPherson K, McNaughton HK, Rochester L, Weatherall M. Community ambulation after stroke... more Lord SE, McPherson K, McNaughton HK, Rochester L, Weatherall M. Community ambulation after stroke: how important and obtainable is it and what measures appear predictive? Arch Phys Med Rehabil 2004;85:234–9.

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Research paper thumbnail of Les stimuli rythmiques ou le cueing à domicile pour améliorer la mobilité des parkinsoniens

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Research paper thumbnail of ResearchOnline@ GCU

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Research paper thumbnail of Re-test reliability and accuracy of the Dikablis eye-tracker when sitting, standing and walking

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Research paper thumbnail of Visual sampling during walking in Parkinson’s disease: impact of visual cues and task complexity

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Research paper thumbnail of Attenuation of upper body accelerations during gait: piloting an innovative assessment tool for Parkinson’s disease

The objective of the current investigation was to explore whether upper body accelerations obtain... more The objective of the current investigation was to explore whether upper body accelerations obtained during gait provide sensitive measures of postural control in people with Parkinson's disease (PD). Thirteen people with PD (70 ± 11 years) and nineteen age-matched controls (70 ± 7 years) walked continuously for two minutes while wearing three inertial sensors located on their lower back (L5), shoulder level (C7), and head. Magnitude (root mean square (RMS)), attenuation (attenuation coefficient), and smoothness (Harmonic ratios, HR) of the accelerations were calculated. People with PD demonstrated greater RMS, particularly in the mediolateral direction, but similar harmonic ratio of head accelerations compared to controls. In addition, they did not attenuate accelerations through the trunk and neck as well as control participants. Our findings indicate that measuring upper body movement provides unique information regarding postural control in PD and that poor attenuation of acceleration from the pelvis to the head contributes to impaired head control. This information is simple to measure and appears to be sensitive to PD and, consequently, is proposed to benefit researchers and clinicians.

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Research paper thumbnail of The attentional demands of walking in PD: effect of cue modality on gait variability

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Research paper thumbnail of An exploration of functional activity in Parkinson's disease using activity monitoring and activity diaries

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Research paper thumbnail of PHYSIOTHERAPY GUIDELINES ON THE USE OF CUEING IN PARKINSON’S DISEASE

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Research paper thumbnail of Cueing training in de thuissituatie verbetert de mobiliteit van mensen met de ziekte van Parkinson

... VAN WEGEN, INGE LIm, ALICE NIEUWBOER, ANNE-mARIE WILLEmS, FABIENNE CHAVRET, DIANA JONES, LYNN... more ... VAN WEGEN, INGE LIm, ALICE NIEUWBOER, ANNE-mARIE WILLEmS, FABIENNE CHAVRET, DIANA JONES, LYNN ROCHESTER, VICkY HETHERINGTON, kATHERINE ... kans om te vallen (Bloem, Van Vugt & Beckley, 2001; Gray & Hildebrand, 2000; Hamani & Lozano, 2003 ...

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Research paper thumbnail of Does deep brain stimulation of the STN in advanced Parkinson's disease change habitual physical activity?

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Research paper thumbnail of Service user and carer involvement in physiotherapy practice, education and research: getting involved for a change

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Research paper thumbnail of Gait variability in Parkinson's disease: Impact of dopamine and attention

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Research paper thumbnail of New metrics for exploring the relationship between mobility and successful ageing

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Research paper thumbnail of Attention rather than spatial memory predicts distinct characteristics of gait in Parkinson's disease

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Research paper thumbnail of The Role of Movement Analysis in Diagnosing and Monitoring Neurodegenerative Conditions: Insights from Gait and Postural Control

Brain Sciences

Quantifying gait and postural control adds valuable information that aids in understanding neurol... more Quantifying gait and postural control adds valuable information that aids in understanding neurological conditions where motor symptoms predominate and cause considerable functional impairment. Disease-specific clinical scales exist; however, they are often susceptible to subjectivity, and can lack sensitivity when identifying subtle gait and postural impairments in prodromal cohorts and longitudinally to document disease progression. Numerous devices are available to objectively quantify a range of measurement outcomes pertaining to gait and postural control; however, efforts are required to standardise and harmonise approaches that are specific to the neurological condition and clinical assessment. Tools are urgently needed that address a number of unmet needs in neurological practice. Namely, these include timely and accurate diagnosis; disease stratification; risk prediction; tracking disease progression; and decision making for intervention optimisation and maximising therapeut...

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Research paper thumbnail of Free-living monitoring of Parkinson’s disease: lessons from the field.

Wearable technology comprises miniaturized sensors (eg, accelerometers) worn on the body and/or p... more Wearable technology comprises miniaturized sensors (eg, accelerometers) worn on the body and/or paired with mobile devices (eg, smart phones) allowing continuous patient monitoring in unsupervised, habitual environments (termed free-living). Wearable technologies are revolutionizing approaches to health care as a result of their utility, accessibility, and affordability. They are positioned to transform Parkinson's disease (PD) management through the provision of individualized, comprehensive, and representative data. This is particularly relevant in PD where symptoms are often triggered by task and free-living environmental challenges that cannot be replicated with sufficient veracity elsewhere. This review concerns use of wearable technology in free-living environments for people with PD. It outlines the potential advantages of wearable technologies and evidence for these to accurately detect and measure clinically relevant features including motor symptoms, falls risk, freezing of gait, gait, functional mobility, and physical activity. Technological limitations and challenges are highlighted, and advances concerning broader aspects are discussed. Recommendations to overcome key challenges are made. To date there is no fully validated system to monitor clinical features or activities in free-living environments. Robust accuracy and validity metrics for some features have been reported, and wearable technology may be used in these cases with a degree of confidence. Utility and acceptability appears reasonable, although testing has largely been informal. Key recommendations include adopting a multidisciplinary approach for standardizing definitions, protocols, and outcomes. Robust validation of developed algorithms and sensor-based metrics is required along with testing of utility. These advances are required before widespread clinical adoption of wearable technology can be realized. © 2016 International Parkinson and Movement Disorder Society.© 2016 International Parkinson and Movement Disorder Society.

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Research paper thumbnail of Free-living gait characteristics in ageing and Parkinson's disease: impact of environment and ambulatory bout length.

Bookmarks Related papers MentionsView impact

Research paper thumbnail of Validation of an accelerometer to quantify a comprehensive battery of gait characteristics in healthy older adults and Parkinson's disease: toward clinical and at home use

IEEE journal of biomedical and health informatics, Jan 2, 2015

Measurement of gait is becoming important as a tool to identify disease and disease progression, ... more Measurement of gait is becoming important as a tool to identify disease and disease progression, yet to date its application is limited largely to specialist centres. Wearable devices enables gait to be measured in naturalistic environments however questions remain regarding validity. Previous research suggests that when compared with a laboratory reference, measurement accuracy is acceptable for mean but not variability or asymmetry gait characteristics. Some fundamental reasons for this have been presented (e.g. synchronisation, different sampling frequencies) but to date this has not been systematically examined. The aims of this study were to: (i) quantify a comprehensive range of gait characteristics measured using a single tri-axial accelerometer-based monitor, (ii) examine outcomes and monitor performance in measuring gait in older adults and those with Parkinson's disease (PD) and (iii) carry out a detailed comparison with those derived from an instrumented walkway to ac...

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Research paper thumbnail of The Effect of Environment and Task on Gait Parameters After Stroke: A Randomized Comparison of Measurement Conditions

Archives of Physical Medicine and Rehabilitation, 2006

Lord SE, Rochester L, Weatherall M, McPherson KM, McNaughton HK. The effect of environment and ta... more Lord SE, Rochester L, Weatherall M, McPherson KM, McNaughton HK. The effect of environment and task on gait parameters after stroke: a randomized comparison of measurement conditions.

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Research paper thumbnail of Community ambulation after stroke: how important and obtainable is it and what measures appear predictive? 1 1 No commercial party having a direct financial interest in the results of the research supporting this article has or will confer a benefit on the author(s) or on any organization with wh...

Archives of Physical Medicine and Rehabilitation, 2004

Lord SE, McPherson K, McNaughton HK, Rochester L, Weatherall M. Community ambulation after stroke... more Lord SE, McPherson K, McNaughton HK, Rochester L, Weatherall M. Community ambulation after stroke: how important and obtainable is it and what measures appear predictive? Arch Phys Med Rehabil 2004;85:234–9.

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Research paper thumbnail of Les stimuli rythmiques ou le cueing à domicile pour améliorer la mobilité des parkinsoniens

Bookmarks Related papers MentionsView impact

Research paper thumbnail of ResearchOnline@ GCU

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Research paper thumbnail of Re-test reliability and accuracy of the Dikablis eye-tracker when sitting, standing and walking

Bookmarks Related papers MentionsView impact

Research paper thumbnail of Visual sampling during walking in Parkinson’s disease: impact of visual cues and task complexity

Bookmarks Related papers MentionsView impact

Research paper thumbnail of Attenuation of upper body accelerations during gait: piloting an innovative assessment tool for Parkinson’s disease

The objective of the current investigation was to explore whether upper body accelerations obtain... more The objective of the current investigation was to explore whether upper body accelerations obtained during gait provide sensitive measures of postural control in people with Parkinson's disease (PD). Thirteen people with PD (70 ± 11 years) and nineteen age-matched controls (70 ± 7 years) walked continuously for two minutes while wearing three inertial sensors located on their lower back (L5), shoulder level (C7), and head. Magnitude (root mean square (RMS)), attenuation (attenuation coefficient), and smoothness (Harmonic ratios, HR) of the accelerations were calculated. People with PD demonstrated greater RMS, particularly in the mediolateral direction, but similar harmonic ratio of head accelerations compared to controls. In addition, they did not attenuate accelerations through the trunk and neck as well as control participants. Our findings indicate that measuring upper body movement provides unique information regarding postural control in PD and that poor attenuation of acceleration from the pelvis to the head contributes to impaired head control. This information is simple to measure and appears to be sensitive to PD and, consequently, is proposed to benefit researchers and clinicians.

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Research paper thumbnail of The attentional demands of walking in PD: effect of cue modality on gait variability

Bookmarks Related papers MentionsView impact

Research paper thumbnail of An exploration of functional activity in Parkinson's disease using activity monitoring and activity diaries

Bookmarks Related papers MentionsView impact

Research paper thumbnail of PHYSIOTHERAPY GUIDELINES ON THE USE OF CUEING IN PARKINSON’S DISEASE

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Research paper thumbnail of Cueing training in de thuissituatie verbetert de mobiliteit van mensen met de ziekte van Parkinson

... VAN WEGEN, INGE LIm, ALICE NIEUWBOER, ANNE-mARIE WILLEmS, FABIENNE CHAVRET, DIANA JONES, LYNN... more ... VAN WEGEN, INGE LIm, ALICE NIEUWBOER, ANNE-mARIE WILLEmS, FABIENNE CHAVRET, DIANA JONES, LYNN ROCHESTER, VICkY HETHERINGTON, kATHERINE ... kans om te vallen (Bloem, Van Vugt & Beckley, 2001; Gray & Hildebrand, 2000; Hamani & Lozano, 2003 ...

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Research paper thumbnail of Does deep brain stimulation of the STN in advanced Parkinson's disease change habitual physical activity?

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Research paper thumbnail of Service user and carer involvement in physiotherapy practice, education and research: getting involved for a change

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Research paper thumbnail of Gait variability in Parkinson's disease: Impact of dopamine and attention

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Research paper thumbnail of New metrics for exploring the relationship between mobility and successful ageing

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Research paper thumbnail of Attention rather than spatial memory predicts distinct characteristics of gait in Parkinson's disease

Bookmarks Related papers MentionsView impact