Mohammad Alavinia | North Khorasan University of Medical Sciences, Bojnurd, Iran (original) (raw)
Papers by Mohammad Alavinia
Razi Journal of Medical Sciences, 2014
Background: One of the industrial worlds for early withdrawal of workers from the workplace. The ... more Background: One of the industrial worlds for early withdrawal of workers from the workplace. The purpose of this study is to introduce a measure for assessing the ability to work in labor to help these workers could be at risk of disability or premature departure from the workplace to be identified Methods: The study population consisted of workers at the power station vertical waiting period under examination was performed. All workers since the end of the follow-up examinations and work performance indicators are measured. Data collection work ability index questionnaire (Work Ability Index) was used. Correlation and regression analysis of data from multi-factor model was used Results: Cross-sectional study was applied. In this study of 385 workers employed in the power plant's ability to forward upright Average score examined in the present study, work ability index score (1/6±)169/39 respectively. This rating is based on the founding of Finland occupational health standards in these questionnaires are good (43-37) are placed. In this study aging workers' work ability index significantly decreased. In this study, a significant association between increased levels of body mass index was not ability to work. Also, the rate of sickness absence and work ability index is significant and inverse relationship So as to reduce the amount of sick leave work ability index increases Conclusion: Work ability index on the set of questionnaire consisting of 7 items that have a reciprocal influence on each other. Current work ability, the number of diseases diagnosed by a physician, Disruption of work Because of illness can explain the effect of reducing ability to work of sick leave is increasing. The main cause of early departure from the workplace Entry delay young work force to work the market for long-term education and leaving early, the elderly, the cause is more important
BMJ Open, Dec 1, 2022
et al. Protocol for a single group, mixed methods study investigating the efficacy of photovoice ... more et al. Protocol for a single group, mixed methods study investigating the efficacy of photovoice to improve self-efficacy related to balance and falls for spinal cord injury. BMJ Open 2022;12:e065684.
The American Journal of Occupational Therapy, 2013
This systematic review synthesized the research on interventions used by occupational therapy pra... more This systematic review synthesized the research on interventions used by occupational therapy practitioners to promote social–emotional development in young children (birth–5 yr) with or at risk for disabilities. After a comprehensive search of the research literature, 23 studies were reviewed and then synthesized into five themes: (1) touch-based interventions to enhance calming and parent–infant bonding, (2) relationship-based interventions to promote positive caregiver–child interactions, (3) joint attention interventions, (4) naturalistic preschool interventions to promote peer-to-peer engagement, and (5) instruction-based interventions to teach children appropriate social behaviors. The interventions for infants primarily involved coaching parents in specific strategies to promote positive interactions; interventions for preschool-age children typically involved encouraging peer support, instructing children, and applying naturalistic behavioral techniques to develop higher-lev...
Journal of NeuroEngineering and Rehabilitation
Background Stroke is a significant contributor of worldwide disability and morbidity with substan... more Background Stroke is a significant contributor of worldwide disability and morbidity with substantial economic consequences. Rehabilitation is a vital component of stroke recovery, but inpatient stroke rehabilitation programs can struggle to meet the recommended hours of therapy per day outlined by the Canadian Stroke Best Practices and American Heart Association. Mobile applications (apps) are an emerging technology which may help bridge this deficit, however this area is understudied. The purpose of this study is to review the effect of mobile apps for stroke rehabilitation on stroke impairments and functional outcomes. Specifically, this paper will delve into the impact of varying mobile app types on stroke rehabilitation. Methods This systematic review included 29 studies: 11 randomized control trials and 18 quasi-experimental studies. Data extrapolation mapped 5 mobile app types (therapy apps, education apps, rehab videos, reminders, and a combination of rehab videos with remin...
arXiv (Cornell University), Oct 26, 2022
The aim of survival analysis in healthcare is to estimate the probability of occurrence of an eve... more The aim of survival analysis in healthcare is to estimate the probability of occurrence of an event, such as a patient's death in an intensive care unit (ICU). Recent developments in deep neural networks (DNNs) for survival analysis show the superiority of these models in comparison with other well-known models in survival analysis applications. Ensuring the reliability and explainability of deep survival models deployed in healthcare is a necessity. Since DNN models often behave like a black box, their predictions might not be easily trusted by clinicians, especially when predictions are contrary to a physician's opinion. A deep survival model that explains and justifies its decision-making process could potentially gain the trust of clinicians. In this research, we propose the reverse survival model (RSM) framework that provides detailed insights into the 1
Journal of Arthropod-Borne Diseases, 2018
Background: We aimed to determine the species composition, richness and diversity indices of the ... more Background: We aimed to determine the species composition, richness and diversity indices of the Phlebotomine sand flies at different topographic condition in visceral (VL) and cutaneous leishmaniasis (CL) foci in the northeast of Iran. Methods: This cross-sectional study was conducted during 2016 in North Khorasan Province. The sampling was focused on rural regions, where human cases of VL and/or CL were diagnosed and reported during last 5 years. Sand flies were collected three times each twenty days during peak periods of seasonal activity. Seven collection methods were used. Some Alpha and Beta diversity indices were calculated. Results: Overall, 7253 sand flies were collected and identified. They were from 19 species of Phlebotominae sandflies. Phlebotomus sergenti and Ph. papatasi were the most prevalent (84.9%) species in the study area. Species richness (S) was very different in three areas and were18, 8, and 4 respectively but Evenness (E) were 0.357, 0.345, and 0.380, so...
American Journal of Physical Medicine & Rehabilitation, 2020
BACKGROUND The nociceptive flexion reflex (NFR) is a physiological, polysynaptic reflex triggered... more BACKGROUND The nociceptive flexion reflex (NFR) is a physiological, polysynaptic reflex triggered by a nociceptive stimulus activating a withdrawal response. In chronic musculoskeletal related pain conditions, a decreased NFR threshold has been suggested as a possible recognition evidence for central sensitization that may cause alteration of central nervous system processing (CNSP). OBJECTIVE To systematically review reported comparisons of the NFR threshold in chronic pain patients and healthy individuals. METHODS Electronic databases covering studies published between January 1990-December 2019 were systematically searched. After application of exclusion criteria 20 studies including 28 trials were included in this review. For meta-analysis, we utilized a random-effects model and funnel plot for publication bias. This research was registered at PROSPERO (CRD42019140354). RESULTS Compared to healthy controls, standardized mean differences in NFR threshold were significantly lower in the total sample of chronic pain patients. Subgroup analysis indicated a homogenous decreased NFR threshold in studies reporting fibromyalgia, chronic pain, and joint pain while heterogeneity existed in other included pain conditions. CONCLUSION A lower NFR threshold in patients suffering from chronic pain conditions may imply hyperexcitability in central nervous system processing. As a preliminary study, the findings would act as a basis for developing a methodology assisting current clinical practices.
Archives of Rehabilitation Research and Clinical Translation, 2021
To determine whether performance on measures of lower extremity muscle strength, sensory function... more To determine whether performance on measures of lower extremity muscle strength, sensory function, postural control, gait speed, and balance self-efficacy could distinguish fallers from nonfallers among ambulatory individuals with spinal cord injury or disease (SCI/D). Design: Prospective cohort study. Setting: Community. Participants: Individuals (NZ26; 6 female, aged 58.9AE18.2y) with motor incomplete SCI/D (American Spinal Injury Association Impairment Scale rating C [nZ5] or D [nZ21]) participated. Participants were 7.5AE9.1 years post injury. Seventeen participants experienced traumatic causes of spinal cord injury. Main Outcome Measures: Participants completed laboratory-based and clinical measures of postural control, gait speed, balance self-efficacy, and lower extremity strength, as well as proprioception and cutaneous pressure sensitivity. Participants were then followed for up to 1 year to track falls using a survey. The survey queried the circumstances and consequences of each fall. If a participant's number of falls equaled or exceeded the median number of falls experience by all participants, they were classified a faller.
Journal of Cardiopulmonary Rehabilitation and Prevention, 2020
PURPOSE The objectives of this study were (1) to assess the effects of a comprehensive education ... more PURPOSE The objectives of this study were (1) to assess the effects of a comprehensive education intervention on maintenance of knowledge, exercise behavior, heart-healthy food intake, self-efficacy, and health literacy 6 mo after comprehensive cardiac rehabilitation (CR), and (2) to identify predictors of exercise maintenance 6 mo after comprehensive CR. METHODS A prospective longitudinal study was conducted to test the effects of a structured educational curriculum in three CR programs in Canada. Participants completed surveys pre-, post-CR and 6 mo post-discharge to assess knowledge, heart-healthy food intake, self-efficacy, and health literacy. Exercise behavior was measured by number of steps/d using a pedometer. RESULTS One hundred twenty participants completed the final survey. Increases in disease-related knowledge and self-efficacy, as well as behavior changes (increases in exercise and heart-healthy food intake), were achieved in comprehensive CR and sustained 6 mo post-program. Exercise maintenance was predicted by changes in heart-healthy food intake, self-efficacy, health literacy, and exercise-related knowledge. CONCLUSIONS In this three-site study focusing on patient education for CR patients in Canada, the benefits of an education intervention in maintaining knowledge, exercise, healthy food intake, and self-efficacy were supported.
Journal of Cardiopulmonary Rehabilitation and Prevention, 2021
PURPOSE Knowledge assessment tools are highly useful in clinical practice, as they help health ca... more PURPOSE Knowledge assessment tools are highly useful in clinical practice, as they help health care teams to customize education and clinical care plans based on the needs of patients. The objective of this study was to develop and validate the DiAbeTes Education Questionnaire (DATE-Q) to measure knowledge among diabetes and prediabetes patients attending cardiac rehabilitation (CR). METHODS Based on patient information needs, other validated tools and diabetes education standards and current practices, experts developed 20 items to comprise the first version of the DATE-Q. To establish content validity, they were reviewed by an expert panel (n = 12) and patients. Refined items were psychometrically tested in 84 diabetes and prediabetes patients attending CR. The internal consistency was assessed via regularized factor analysis and Cronbach α, and criterion validity with regard to patient education and family income. For interpretability analysis, the minimal clinically important difference (MCID) was estimated using distribution- and anchor-based methods. RESULTS All items were appropriate for administration in this population according to experts and patients. Three factors were extracted and were generally internally consistent and well defined by the items. Criterion validity was supported by significant differences in mean scores by family income (P < .05). Results showed that increases in knowledge can moderately increase mean steps/d and peak oxygen uptake, with an MCID of 2.13. CONCLUSIONS This study demonstrated preliminary validity of the DATE-Q. Future research is needed to assess other measurement properties to confirm the applicability of this tool in clinical and research settings.
Archives of Physical Medicine and Rehabilitation, 2021
OBJECTIVE To examine the associations among social networks and loneliness on health and life sat... more OBJECTIVE To examine the associations among social networks and loneliness on health and life satisfaction in adults with chronic spinal cord injury / dysfunction (SCI/D). DESIGN Cross-sectional telephone survey study. SETTING Tertiary SCI rehabilitation centre. Ontario, Canada. PARTICIPANTS Community-dwelling adults with chronic SCI/D (N=170). INTERVENTION Not applicable MAIN OUTCOME MEASURES: The main outcome measures were the Short-Form 36 (SF-36) to assess health and the Life Satisfaction-11 (LiSAT-11) to assess life satisfaction. RESULTS A hierarchical regression model predicting physical health accounted for 24% (p<.001) of the variance. The only social network variable to significantly contribute to the model was having a higher proportion of family members living in one's household (p<.05). A model predicting mental health accounted for 44% (p<.001) of the variance, with having a higher proportion of family members living in one's household (p<.05) and lower feelings of loneliness (p<.001) being associated with better mental health. Finally, the model predicting life satisfaction accounted for 62% (p<.001) of the variance, with lower greater levels of social network intimacy (p<.01) and lower feelings of loneliness (p<.001) being significant predictors. CONCLUSIONS These findings highlight the importance of having access to family members in one's home for better physical and mental health post-SCI/D as well as the negative association between loneliness and mental health and life satisfaction. There is a need for approaches to ensure that people with SCI/D in the community feel supported to mitigate feelings of loneliness in order to optimize their health and wellbeing.
Journal of Arthropod-Borne Diseases, 2021
Background: Ticks are considered as the main vectors for the transmission of various pathogens su... more Background: Ticks are considered as the main vectors for the transmission of various pathogens such as relapsing fever and CCHF to humans. This study was investigated the biodiversity indices and medically importance of ticks in North Khorasan Province, Northeast of Iran during 2015–2019. Methods: Specimens were captured from infested ruminants including cows, sheep, and goats. Additionally, tick collections also were performed on non-domesticated creatures such as turtles, rodents, and hedgehogs. Specimens were identified using valid identification keys. Species diversity, species richness and evenness indices have been calculated to estimate species biodiversity of ticks. Results: A total of 1478 adult ticks were collected. The specimens were from two families: Ixodidae (90.05%) and Argasidae (9.95%), 6 genera and 17 species including: Rhipicephalus sanguineus (55.9%), Rhipicephalus bursa (13.4%), Hyalomma marginatum (9.5%), Hyalomma anatolicum (9.5%), Hyalomma asiaticum (0.2%),...
International Journal of Infectious Diseases, 2020
12%, in cross bred 22.7% and in local 18.9% through RBPT, while it was 4%, 15.3% and 12.7% throug... more 12%, in cross bred 22.7% and in local 18.9% through RBPT, while it was 4%, 15.3% and 12.7% through SAT in exotic, cross bred and local cattle, respectively. It was found that the occurrence of brucellosis was positively associated with increased TLC, AST, ALT and SD. On other hand Hb, TEC, TLC, neutrophils, eosinophils, lymphocytes and monocytes counts were decreased in positive animals. Conclusion: In conclusion, Brucellosis in Lahore-Pakistan is a serious problem among dairy herds and inducing inimical impact on commercial dairy farmers' economy. The seroprevalence varies across animal breeds with variable deleterious changes in hematological parameters and serum biochemistry.
International Journal of Infectious Diseases, 2016
Background: Leptospirosis is a zoonotic diseases caused by leptospires,which is belonged to speci... more Background: Leptospirosis is a zoonotic diseases caused by leptospires,which is belonged to species of Leptospirainterroganscontaining over 212 serovars. Rodents can act as a major source of infection for humans and animals. The disease has a global distribution, mainly in humid, tropical and subtropical regions. In Iran the disease is endemic in some parts of the north of the country. Methods & Materials: This study was conducted to investigate the existenceand important ofLeptospira species in rodent of North Khorasan Province, Iran. For this study, thirty six rodents were trapped alive. Blood samples were taken and serum were separated and kept in freezer for serological investigation. The seropositiveserovars were identified and the antibody titers were measured bythe standard microscopic agglutination test(MAT), using a panel of 8 strains of live Leptospira species as antigens. Serial dilutions (1/100 to 1/1600) of serum were used. Results: The result of this study showed that 12 samples (33%) had a positive reaction against one or twosarovars. In general, 5 samples had a posistive reaction with serovar Pomona, 3 samples with Australis, 2 samples with Taraseviand 2 samples with Icterohaemorrhagiae. Theresults also showed that the most prevalent leptospiraserovar was Pomona (14%) and the most common titer was 1/100 (10 samples) and thehighest titer was 1/200 (2 samples). Conclusion: This study of leptospirosis is the first one in rodents in this region and it showed that Leptospirosis is prevalent in rodents in North Khorasan Province. However, further study is required to determine the importance of rodents in circulating the Leptospires into the animal and human populations.
ArXiv, 2022
This paper introduces a novel non-parametric deep model for estimating time-to-event (survival an... more This paper introduces a novel non-parametric deep model for estimating time-to-event (survival analysis) in presence of censored data and competing risks. The model is designed based on the sequence-to-sequence (Seq2Seq) architecture, therefore we name it Survival Seq2Seq. The first recurrent neural network (RNN) layer of the encoder of our model is made up of Gated Recurrent Unit with Decay (GRU-D) cells. These cells have the ability to effectively impute not-missing-at-random values of longitudinal datasets with very high missing rates, such as electronic health records (EHRs). The decoder of Survival Seq2Seq generates a probability distribution function (PDF) for each competing risk without assuming any prior distribution for the risks. Taking advantage of RNN cells, the decoder is able to generate smooth and virtually spike-free PDFs. This is beyond the capability of existing non-parametric deep models for survival analysis. Training results on synthetic and medical datasets prov...
Heliyon, 2021
Leptospirosis is an important zoonotic bacterial disease caused by Leptospira spp. Earlier studie... more Leptospirosis is an important zoonotic bacterial disease caused by Leptospira spp. Earlier studies from North Khorasan province (Iran) reported the presence of Leptospira in wild canines and rodents. To date, there is no data on the seroprevalence of leptospirosis among humans in this province. This study was performed to determine the prevalence of human leptospiral infection among people with different occupations. The study was conducted in urban and rural areas of the province. Among the serum samples collected from 278 subjects, 3 (1.1%) showed positive reaction with titer of 1:100 by the microscopic agglutination test (MAT). Positive reactions were detected against Leptospira interrogans Canicola and L. interrogans icterohemorrhagic and all these samples were from livestock farmers (n ¼ 3/106, 2.7%). The current study revealed that, though Leptospira infection is low in North Khorasan province, regular monitoring of the livestock and the farmers are important.
Nephrology, 2021
The commonly used 24‐hour collection technique has been the mainstay of diagnosis for supersatura... more The commonly used 24‐hour collection technique has been the mainstay of diagnosis for supersaturation but has some certain limitations. Hence, superiority of multiple short urine collections as a new alternative in precipitation risk assessment was assessed compared to the standard 24‐hour urine collection among healthy subjects.
Background: Rodents are an important source of zoonotic diseases for human. The aim of this study... more Background: Rodents are an important source of zoonotic diseases for human. The aim of this study was to determine the infectivity of rodents with intestinal helminths in North Khorasan Province, Iran. Methods: One hundred and thirteen rodents were collected using different collection methods such as kill and live traps, digging of their burrow, filling of their hiding places with water and hand net during 2011-2013. Their alimentary canals were removed in the laboratory and helminths were determined in the department of parasitology, Tehran University of Medical Sciences. Results: Thirteen species of helminths parasites were found in 13 species of rodents , including Aspiculuris tetraptera, Hymenolepis diminuta, Nippostrongylus brasiliensis, Protospirura Seurat, Rictolaria ratti, Skrjabinitaenia lobata, Streptopharagus kuntzi, Syphacia obvelata, Taenia taeniaeformis, Trichuris muris, Cysticercus fasciolaris, Acanthocephal. spp and Trichuris spp. Some of them were reported for the f...
American Journal of Physical Medicine & Rehabilitation
Frontiers in Neurology
Introduction: Impaired balance leads to falls in individuals with motor incomplete spinal cord in... more Introduction: Impaired balance leads to falls in individuals with motor incomplete spinal cord injury or disease (iSCI/D). Reactive stepping is a strategy used to prevent falls and Perturbation-based Balance Training (PBT) can improve this ability.Objective: The objective of this study was to determine if PBT results in greater improvements in reactive stepping ability than frequency-matched Conventional Intensive Balance Training (CIBT) in adults with iSCI/D.Design: Randomized clinical trial.Setting: Tertiary SCI/D rehabilitation center.Participants: Twenty-one adults with chronic (>1 year) iSCI/D were randomized. Due to one drop out 20 participants completed the study.Methods: Participants were randomly allocated to complete either PBT or CIBT three times per week for 8 weeks. Both programs included challenging static and dynamic balance tasks, but the PBT group also experienced manual external balance perturbations.Main Outcome Measures: Assessments of reactive stepping abilit...
Razi Journal of Medical Sciences, 2014
Background: One of the industrial worlds for early withdrawal of workers from the workplace. The ... more Background: One of the industrial worlds for early withdrawal of workers from the workplace. The purpose of this study is to introduce a measure for assessing the ability to work in labor to help these workers could be at risk of disability or premature departure from the workplace to be identified Methods: The study population consisted of workers at the power station vertical waiting period under examination was performed. All workers since the end of the follow-up examinations and work performance indicators are measured. Data collection work ability index questionnaire (Work Ability Index) was used. Correlation and regression analysis of data from multi-factor model was used Results: Cross-sectional study was applied. In this study of 385 workers employed in the power plant's ability to forward upright Average score examined in the present study, work ability index score (1/6±)169/39 respectively. This rating is based on the founding of Finland occupational health standards in these questionnaires are good (43-37) are placed. In this study aging workers' work ability index significantly decreased. In this study, a significant association between increased levels of body mass index was not ability to work. Also, the rate of sickness absence and work ability index is significant and inverse relationship So as to reduce the amount of sick leave work ability index increases Conclusion: Work ability index on the set of questionnaire consisting of 7 items that have a reciprocal influence on each other. Current work ability, the number of diseases diagnosed by a physician, Disruption of work Because of illness can explain the effect of reducing ability to work of sick leave is increasing. The main cause of early departure from the workplace Entry delay young work force to work the market for long-term education and leaving early, the elderly, the cause is more important
BMJ Open, Dec 1, 2022
et al. Protocol for a single group, mixed methods study investigating the efficacy of photovoice ... more et al. Protocol for a single group, mixed methods study investigating the efficacy of photovoice to improve self-efficacy related to balance and falls for spinal cord injury. BMJ Open 2022;12:e065684.
The American Journal of Occupational Therapy, 2013
This systematic review synthesized the research on interventions used by occupational therapy pra... more This systematic review synthesized the research on interventions used by occupational therapy practitioners to promote social–emotional development in young children (birth–5 yr) with or at risk for disabilities. After a comprehensive search of the research literature, 23 studies were reviewed and then synthesized into five themes: (1) touch-based interventions to enhance calming and parent–infant bonding, (2) relationship-based interventions to promote positive caregiver–child interactions, (3) joint attention interventions, (4) naturalistic preschool interventions to promote peer-to-peer engagement, and (5) instruction-based interventions to teach children appropriate social behaviors. The interventions for infants primarily involved coaching parents in specific strategies to promote positive interactions; interventions for preschool-age children typically involved encouraging peer support, instructing children, and applying naturalistic behavioral techniques to develop higher-lev...
Journal of NeuroEngineering and Rehabilitation
Background Stroke is a significant contributor of worldwide disability and morbidity with substan... more Background Stroke is a significant contributor of worldwide disability and morbidity with substantial economic consequences. Rehabilitation is a vital component of stroke recovery, but inpatient stroke rehabilitation programs can struggle to meet the recommended hours of therapy per day outlined by the Canadian Stroke Best Practices and American Heart Association. Mobile applications (apps) are an emerging technology which may help bridge this deficit, however this area is understudied. The purpose of this study is to review the effect of mobile apps for stroke rehabilitation on stroke impairments and functional outcomes. Specifically, this paper will delve into the impact of varying mobile app types on stroke rehabilitation. Methods This systematic review included 29 studies: 11 randomized control trials and 18 quasi-experimental studies. Data extrapolation mapped 5 mobile app types (therapy apps, education apps, rehab videos, reminders, and a combination of rehab videos with remin...
arXiv (Cornell University), Oct 26, 2022
The aim of survival analysis in healthcare is to estimate the probability of occurrence of an eve... more The aim of survival analysis in healthcare is to estimate the probability of occurrence of an event, such as a patient's death in an intensive care unit (ICU). Recent developments in deep neural networks (DNNs) for survival analysis show the superiority of these models in comparison with other well-known models in survival analysis applications. Ensuring the reliability and explainability of deep survival models deployed in healthcare is a necessity. Since DNN models often behave like a black box, their predictions might not be easily trusted by clinicians, especially when predictions are contrary to a physician's opinion. A deep survival model that explains and justifies its decision-making process could potentially gain the trust of clinicians. In this research, we propose the reverse survival model (RSM) framework that provides detailed insights into the 1
Journal of Arthropod-Borne Diseases, 2018
Background: We aimed to determine the species composition, richness and diversity indices of the ... more Background: We aimed to determine the species composition, richness and diversity indices of the Phlebotomine sand flies at different topographic condition in visceral (VL) and cutaneous leishmaniasis (CL) foci in the northeast of Iran. Methods: This cross-sectional study was conducted during 2016 in North Khorasan Province. The sampling was focused on rural regions, where human cases of VL and/or CL were diagnosed and reported during last 5 years. Sand flies were collected three times each twenty days during peak periods of seasonal activity. Seven collection methods were used. Some Alpha and Beta diversity indices were calculated. Results: Overall, 7253 sand flies were collected and identified. They were from 19 species of Phlebotominae sandflies. Phlebotomus sergenti and Ph. papatasi were the most prevalent (84.9%) species in the study area. Species richness (S) was very different in three areas and were18, 8, and 4 respectively but Evenness (E) were 0.357, 0.345, and 0.380, so...
American Journal of Physical Medicine & Rehabilitation, 2020
BACKGROUND The nociceptive flexion reflex (NFR) is a physiological, polysynaptic reflex triggered... more BACKGROUND The nociceptive flexion reflex (NFR) is a physiological, polysynaptic reflex triggered by a nociceptive stimulus activating a withdrawal response. In chronic musculoskeletal related pain conditions, a decreased NFR threshold has been suggested as a possible recognition evidence for central sensitization that may cause alteration of central nervous system processing (CNSP). OBJECTIVE To systematically review reported comparisons of the NFR threshold in chronic pain patients and healthy individuals. METHODS Electronic databases covering studies published between January 1990-December 2019 were systematically searched. After application of exclusion criteria 20 studies including 28 trials were included in this review. For meta-analysis, we utilized a random-effects model and funnel plot for publication bias. This research was registered at PROSPERO (CRD42019140354). RESULTS Compared to healthy controls, standardized mean differences in NFR threshold were significantly lower in the total sample of chronic pain patients. Subgroup analysis indicated a homogenous decreased NFR threshold in studies reporting fibromyalgia, chronic pain, and joint pain while heterogeneity existed in other included pain conditions. CONCLUSION A lower NFR threshold in patients suffering from chronic pain conditions may imply hyperexcitability in central nervous system processing. As a preliminary study, the findings would act as a basis for developing a methodology assisting current clinical practices.
Archives of Rehabilitation Research and Clinical Translation, 2021
To determine whether performance on measures of lower extremity muscle strength, sensory function... more To determine whether performance on measures of lower extremity muscle strength, sensory function, postural control, gait speed, and balance self-efficacy could distinguish fallers from nonfallers among ambulatory individuals with spinal cord injury or disease (SCI/D). Design: Prospective cohort study. Setting: Community. Participants: Individuals (NZ26; 6 female, aged 58.9AE18.2y) with motor incomplete SCI/D (American Spinal Injury Association Impairment Scale rating C [nZ5] or D [nZ21]) participated. Participants were 7.5AE9.1 years post injury. Seventeen participants experienced traumatic causes of spinal cord injury. Main Outcome Measures: Participants completed laboratory-based and clinical measures of postural control, gait speed, balance self-efficacy, and lower extremity strength, as well as proprioception and cutaneous pressure sensitivity. Participants were then followed for up to 1 year to track falls using a survey. The survey queried the circumstances and consequences of each fall. If a participant's number of falls equaled or exceeded the median number of falls experience by all participants, they were classified a faller.
Journal of Cardiopulmonary Rehabilitation and Prevention, 2020
PURPOSE The objectives of this study were (1) to assess the effects of a comprehensive education ... more PURPOSE The objectives of this study were (1) to assess the effects of a comprehensive education intervention on maintenance of knowledge, exercise behavior, heart-healthy food intake, self-efficacy, and health literacy 6 mo after comprehensive cardiac rehabilitation (CR), and (2) to identify predictors of exercise maintenance 6 mo after comprehensive CR. METHODS A prospective longitudinal study was conducted to test the effects of a structured educational curriculum in three CR programs in Canada. Participants completed surveys pre-, post-CR and 6 mo post-discharge to assess knowledge, heart-healthy food intake, self-efficacy, and health literacy. Exercise behavior was measured by number of steps/d using a pedometer. RESULTS One hundred twenty participants completed the final survey. Increases in disease-related knowledge and self-efficacy, as well as behavior changes (increases in exercise and heart-healthy food intake), were achieved in comprehensive CR and sustained 6 mo post-program. Exercise maintenance was predicted by changes in heart-healthy food intake, self-efficacy, health literacy, and exercise-related knowledge. CONCLUSIONS In this three-site study focusing on patient education for CR patients in Canada, the benefits of an education intervention in maintaining knowledge, exercise, healthy food intake, and self-efficacy were supported.
Journal of Cardiopulmonary Rehabilitation and Prevention, 2021
PURPOSE Knowledge assessment tools are highly useful in clinical practice, as they help health ca... more PURPOSE Knowledge assessment tools are highly useful in clinical practice, as they help health care teams to customize education and clinical care plans based on the needs of patients. The objective of this study was to develop and validate the DiAbeTes Education Questionnaire (DATE-Q) to measure knowledge among diabetes and prediabetes patients attending cardiac rehabilitation (CR). METHODS Based on patient information needs, other validated tools and diabetes education standards and current practices, experts developed 20 items to comprise the first version of the DATE-Q. To establish content validity, they were reviewed by an expert panel (n = 12) and patients. Refined items were psychometrically tested in 84 diabetes and prediabetes patients attending CR. The internal consistency was assessed via regularized factor analysis and Cronbach α, and criterion validity with regard to patient education and family income. For interpretability analysis, the minimal clinically important difference (MCID) was estimated using distribution- and anchor-based methods. RESULTS All items were appropriate for administration in this population according to experts and patients. Three factors were extracted and were generally internally consistent and well defined by the items. Criterion validity was supported by significant differences in mean scores by family income (P < .05). Results showed that increases in knowledge can moderately increase mean steps/d and peak oxygen uptake, with an MCID of 2.13. CONCLUSIONS This study demonstrated preliminary validity of the DATE-Q. Future research is needed to assess other measurement properties to confirm the applicability of this tool in clinical and research settings.
Archives of Physical Medicine and Rehabilitation, 2021
OBJECTIVE To examine the associations among social networks and loneliness on health and life sat... more OBJECTIVE To examine the associations among social networks and loneliness on health and life satisfaction in adults with chronic spinal cord injury / dysfunction (SCI/D). DESIGN Cross-sectional telephone survey study. SETTING Tertiary SCI rehabilitation centre. Ontario, Canada. PARTICIPANTS Community-dwelling adults with chronic SCI/D (N=170). INTERVENTION Not applicable MAIN OUTCOME MEASURES: The main outcome measures were the Short-Form 36 (SF-36) to assess health and the Life Satisfaction-11 (LiSAT-11) to assess life satisfaction. RESULTS A hierarchical regression model predicting physical health accounted for 24% (p<.001) of the variance. The only social network variable to significantly contribute to the model was having a higher proportion of family members living in one's household (p<.05). A model predicting mental health accounted for 44% (p<.001) of the variance, with having a higher proportion of family members living in one's household (p<.05) and lower feelings of loneliness (p<.001) being associated with better mental health. Finally, the model predicting life satisfaction accounted for 62% (p<.001) of the variance, with lower greater levels of social network intimacy (p<.01) and lower feelings of loneliness (p<.001) being significant predictors. CONCLUSIONS These findings highlight the importance of having access to family members in one's home for better physical and mental health post-SCI/D as well as the negative association between loneliness and mental health and life satisfaction. There is a need for approaches to ensure that people with SCI/D in the community feel supported to mitigate feelings of loneliness in order to optimize their health and wellbeing.
Journal of Arthropod-Borne Diseases, 2021
Background: Ticks are considered as the main vectors for the transmission of various pathogens su... more Background: Ticks are considered as the main vectors for the transmission of various pathogens such as relapsing fever and CCHF to humans. This study was investigated the biodiversity indices and medically importance of ticks in North Khorasan Province, Northeast of Iran during 2015–2019. Methods: Specimens were captured from infested ruminants including cows, sheep, and goats. Additionally, tick collections also were performed on non-domesticated creatures such as turtles, rodents, and hedgehogs. Specimens were identified using valid identification keys. Species diversity, species richness and evenness indices have been calculated to estimate species biodiversity of ticks. Results: A total of 1478 adult ticks were collected. The specimens were from two families: Ixodidae (90.05%) and Argasidae (9.95%), 6 genera and 17 species including: Rhipicephalus sanguineus (55.9%), Rhipicephalus bursa (13.4%), Hyalomma marginatum (9.5%), Hyalomma anatolicum (9.5%), Hyalomma asiaticum (0.2%),...
International Journal of Infectious Diseases, 2020
12%, in cross bred 22.7% and in local 18.9% through RBPT, while it was 4%, 15.3% and 12.7% throug... more 12%, in cross bred 22.7% and in local 18.9% through RBPT, while it was 4%, 15.3% and 12.7% through SAT in exotic, cross bred and local cattle, respectively. It was found that the occurrence of brucellosis was positively associated with increased TLC, AST, ALT and SD. On other hand Hb, TEC, TLC, neutrophils, eosinophils, lymphocytes and monocytes counts were decreased in positive animals. Conclusion: In conclusion, Brucellosis in Lahore-Pakistan is a serious problem among dairy herds and inducing inimical impact on commercial dairy farmers' economy. The seroprevalence varies across animal breeds with variable deleterious changes in hematological parameters and serum biochemistry.
International Journal of Infectious Diseases, 2016
Background: Leptospirosis is a zoonotic diseases caused by leptospires,which is belonged to speci... more Background: Leptospirosis is a zoonotic diseases caused by leptospires,which is belonged to species of Leptospirainterroganscontaining over 212 serovars. Rodents can act as a major source of infection for humans and animals. The disease has a global distribution, mainly in humid, tropical and subtropical regions. In Iran the disease is endemic in some parts of the north of the country. Methods & Materials: This study was conducted to investigate the existenceand important ofLeptospira species in rodent of North Khorasan Province, Iran. For this study, thirty six rodents were trapped alive. Blood samples were taken and serum were separated and kept in freezer for serological investigation. The seropositiveserovars were identified and the antibody titers were measured bythe standard microscopic agglutination test(MAT), using a panel of 8 strains of live Leptospira species as antigens. Serial dilutions (1/100 to 1/1600) of serum were used. Results: The result of this study showed that 12 samples (33%) had a positive reaction against one or twosarovars. In general, 5 samples had a posistive reaction with serovar Pomona, 3 samples with Australis, 2 samples with Taraseviand 2 samples with Icterohaemorrhagiae. Theresults also showed that the most prevalent leptospiraserovar was Pomona (14%) and the most common titer was 1/100 (10 samples) and thehighest titer was 1/200 (2 samples). Conclusion: This study of leptospirosis is the first one in rodents in this region and it showed that Leptospirosis is prevalent in rodents in North Khorasan Province. However, further study is required to determine the importance of rodents in circulating the Leptospires into the animal and human populations.
ArXiv, 2022
This paper introduces a novel non-parametric deep model for estimating time-to-event (survival an... more This paper introduces a novel non-parametric deep model for estimating time-to-event (survival analysis) in presence of censored data and competing risks. The model is designed based on the sequence-to-sequence (Seq2Seq) architecture, therefore we name it Survival Seq2Seq. The first recurrent neural network (RNN) layer of the encoder of our model is made up of Gated Recurrent Unit with Decay (GRU-D) cells. These cells have the ability to effectively impute not-missing-at-random values of longitudinal datasets with very high missing rates, such as electronic health records (EHRs). The decoder of Survival Seq2Seq generates a probability distribution function (PDF) for each competing risk without assuming any prior distribution for the risks. Taking advantage of RNN cells, the decoder is able to generate smooth and virtually spike-free PDFs. This is beyond the capability of existing non-parametric deep models for survival analysis. Training results on synthetic and medical datasets prov...
Heliyon, 2021
Leptospirosis is an important zoonotic bacterial disease caused by Leptospira spp. Earlier studie... more Leptospirosis is an important zoonotic bacterial disease caused by Leptospira spp. Earlier studies from North Khorasan province (Iran) reported the presence of Leptospira in wild canines and rodents. To date, there is no data on the seroprevalence of leptospirosis among humans in this province. This study was performed to determine the prevalence of human leptospiral infection among people with different occupations. The study was conducted in urban and rural areas of the province. Among the serum samples collected from 278 subjects, 3 (1.1%) showed positive reaction with titer of 1:100 by the microscopic agglutination test (MAT). Positive reactions were detected against Leptospira interrogans Canicola and L. interrogans icterohemorrhagic and all these samples were from livestock farmers (n ¼ 3/106, 2.7%). The current study revealed that, though Leptospira infection is low in North Khorasan province, regular monitoring of the livestock and the farmers are important.
Nephrology, 2021
The commonly used 24‐hour collection technique has been the mainstay of diagnosis for supersatura... more The commonly used 24‐hour collection technique has been the mainstay of diagnosis for supersaturation but has some certain limitations. Hence, superiority of multiple short urine collections as a new alternative in precipitation risk assessment was assessed compared to the standard 24‐hour urine collection among healthy subjects.
Background: Rodents are an important source of zoonotic diseases for human. The aim of this study... more Background: Rodents are an important source of zoonotic diseases for human. The aim of this study was to determine the infectivity of rodents with intestinal helminths in North Khorasan Province, Iran. Methods: One hundred and thirteen rodents were collected using different collection methods such as kill and live traps, digging of their burrow, filling of their hiding places with water and hand net during 2011-2013. Their alimentary canals were removed in the laboratory and helminths were determined in the department of parasitology, Tehran University of Medical Sciences. Results: Thirteen species of helminths parasites were found in 13 species of rodents , including Aspiculuris tetraptera, Hymenolepis diminuta, Nippostrongylus brasiliensis, Protospirura Seurat, Rictolaria ratti, Skrjabinitaenia lobata, Streptopharagus kuntzi, Syphacia obvelata, Taenia taeniaeformis, Trichuris muris, Cysticercus fasciolaris, Acanthocephal. spp and Trichuris spp. Some of them were reported for the f...
American Journal of Physical Medicine & Rehabilitation
Frontiers in Neurology
Introduction: Impaired balance leads to falls in individuals with motor incomplete spinal cord in... more Introduction: Impaired balance leads to falls in individuals with motor incomplete spinal cord injury or disease (iSCI/D). Reactive stepping is a strategy used to prevent falls and Perturbation-based Balance Training (PBT) can improve this ability.Objective: The objective of this study was to determine if PBT results in greater improvements in reactive stepping ability than frequency-matched Conventional Intensive Balance Training (CIBT) in adults with iSCI/D.Design: Randomized clinical trial.Setting: Tertiary SCI/D rehabilitation center.Participants: Twenty-one adults with chronic (>1 year) iSCI/D were randomized. Due to one drop out 20 participants completed the study.Methods: Participants were randomly allocated to complete either PBT or CIBT three times per week for 8 weeks. Both programs included challenging static and dynamic balance tasks, but the PBT group also experienced manual external balance perturbations.Main Outcome Measures: Assessments of reactive stepping abilit...