Kyle Nolla | Northwestern University (original) (raw)
Papers by Kyle Nolla
Journal of clinical oncology, Jun 1, 2024
The Journal of urology/The journal of urology, May 1, 2024
Journal of patient-reported outcomes, Mar 21, 2024
Applied Clinical Informatics, Dec 27, 2023
► clinical informatics ► electronic health records ► IT design and development methodologies ► pa... more ► clinical informatics ► electronic health records ► IT design and development methodologies ► patient-reported outcome measures ► health informatics interoperability
Competitive video gaming or esports is a field with the potential for gender-equal competition. H... more Competitive video gaming or esports is a field with the potential for gender-equal competition. However, esports is dominated by cisgender men at both the casual and professional levels. When a field is highly gender-imbalanced, gender minority groups tend to perceive the field as unwelcoming, which reduces interest in the field and further perpetuates unequal participation. One potential pathway to encourage interest and participation is the creation of gender-specific spaces, such as women-only tournaments in esports. To study the group effects of gender on tournament experience, we recruited cisgender women who were novice gamers for in-laboratory, one-on-one esports tournaments under two conditions: in women-only tournaments or mixedgender tournaments with equally novice cisgender men. Our results show that in matches between men and women, women underperformed against men regardless of whether her opponent had played more often, less often, or equal to her in the past year. In addition, women who played in women-only tournaments gave more accurate estimates of their skill and reported greater task importance than women who played in mixed-gender tournaments. In practice, women-only tournaments may aid recruitment and retention of women in esports as a supplement to gameplay in mixed-gender competitive spaces.
The Journal of Urology, Apr 1, 2023
Nature Reviews Urology, Mar 16, 2023
S37 nosed patients, how disease and treatment(s) impact patients' lives, and assess content valid... more S37 nosed patients, how disease and treatment(s) impact patients' lives, and assess content validity of PRO instruments (EORTC QLQ-OG25; EORTC QLQ-C30). MethodS: The most frequently experienced symptoms or impacts of advanced/metastatic GA/GEJ, and their degree of disturbance, were identified in qualitative interviews with recently diagnosed patients. Disturbance by symptoms or impacts was rated on a scale of 0 (not at all) to 10 (extremely). Frequency of prompted vs. unprompted responses and mean disturbance ratings were tabulated. Patients were asked cognitive interview questions to assess their comprehension of the QLQ-OG25 and QLQ-C30. ReSultS: Nine patients (n= 3 GA; n= 6 GEJ), on or off treatment, were interviewed. The majority of patients reported multiple disease-specific symptoms with moderate mean disturbance, including difficulty eating (89%; disturbance= 6.5), difficulty swallowing (78%; disturbance= 6.4), and abdominal pain (78%; disturbance= 7.4). Weakness (100%; disturbance= 5.4), anxiety (89%; disturbance= 5.9), inability to work (67%; dis-turbance= 7.5), and interference with daily activities (67%; disturbance= 7.0) were also reported. Additional symptom burden experienced by patients (e.g., loss of appetite, nausea, fatigue) was attributed to previous or ongoing treatments, particularly chemotherapy. Patients indicated the majority of items in the QLQ-OG25 and QLQ-C30 were easily understood and relevant to their experience with GA/GEJ. PRO instrument length was not a concern; patients thought completing these questionnaires, or instruments of similar length, would be easily done with important information collected. ConCluSionS: Patients with recently diagnosed advanced/metastatic GA/GEJ reported a variety of symptoms and impacts attributed to their underlying disease and/or treatments. The most important and relevant symptoms and impacts identified in the interviews can be assessed by the QLQ-OG25 and QLQ-C30. Our data provide evidence that PRO instruments are appropriate to measure symptoms and impacts in this population.
Future Oncology, Dec 1, 2022
Advanced renal cell carcinoma (RCC) remains a challenging oncologic disease to treat despite adva... more Advanced renal cell carcinoma (RCC) remains a challenging oncologic disease to treat despite advancements in therapeutics. Nonetheless, the development of tyrosine kinase inhibitors (TKIs) and immunotherapy has drastically altered the treatment landscape for advanced RCC over the past decade. The current standard-of-care treatment for advanced RCC involves combination TKI and immunotherapy regimens including cabozantinib and nivolumab as studied in the CheckMate 9ER trial. This review summarizes the preclinical and clinical evidence that led to the CheckMate 9ER study, as well as pertinent study aspects such as treatment efficacy, adverse events and patient-related outcomes.
Child Development, Mar 20, 2018
This meta-analysis, spanning 5 decades of Draw-A-Scientist studies, examined U.S. children's gend... more This meta-analysis, spanning 5 decades of Draw-A-Scientist studies, examined U.S. children's gender-science stereotypes linking science with men. These stereotypes should have weakened over time because women's representation in science has risen substantially in the United States, and mass media increasingly depict female scientists. Based on 78 studies (N = 20,860; grades K-12), children's drawings of scientists depicted female scientists more often in later decades, but less often among older children. Children's depictions of scientists therefore have become more gender diverse over time, but children still associate science with men as they grow older. These results may reflect that children observe more male than female scientists in their environments, even though women's representation in science has increased over time.
Journal of Electronic Gaming and Esports
Competitive video gaming or esports is a field with the potential for gender-equal competition. H... more Competitive video gaming or esports is a field with the potential for gender-equal competition. However, esports is dominated by cisgender men at both the casual and professional levels. When a field is highly gender-imbalanced, gender minority groups tend to perceive the field as unwelcoming, which reduces interest in the field and further perpetuates unequal participation. One potential pathway to encourage interest and participation is the creation of gender-specific spaces, such as women-only tournaments in esports. To study the group effects of gender on tournament experience, we recruited cisgender women who were novice gamers for in-laboratory, one-on-one esports tournaments under two conditions: in women-only tournaments or mixed-gender tournaments with equally novice cisgender men. Our results show that in matches between men and women, women underperformed against men regardless of whether her opponent had played more often, less often, or equal to her in the past year. In...
Future Oncology
Advanced renal cell carcinoma (RCC) remains a challenging oncologic disease to treat despite adva... more Advanced renal cell carcinoma (RCC) remains a challenging oncologic disease to treat despite advancements in therapeutics. Nonetheless, the development of tyrosine kinase inhibitors (TKIs) and immunotherapy has drastically altered the treatment landscape for advanced RCC over the past decade. The current standard-of-care treatment for advanced RCC involves combination TKI and immunotherapy regimens including cabozantinib and nivolumab as studied in the CheckMate 9ER trial. This review summarizes the preclinical and clinical evidence that led to the CheckMate 9ER study, as well as pertinent study aspects such as treatment efficacy, adverse events and patient-related outcomes.
Self-ratings of pre-match arousal predict tournament performance in real-world Super Smash Bros M... more Self-ratings of pre-match arousal predict tournament performance in real-world Super Smash Bros Melee players. Much of this effect is driven by justified expectation of loss, but even then general pre-match arousal exerts a negative, marginal effect on performance.
Although each of you specializes in fields that are distinct from gender and gaming, you've never... more Although each of you specializes in fields that are distinct from gender and gaming, you've nevertheless provided me with infinite guidance, scientific wisdom, and support both structural and emotional. Without your patience and flexibility, I would never have been able to explore the issues at the center of this dissertation. I'm also extremely grateful to my committee members Alice Eagly and Wendi Gardner, whose expertise in issues of gender, identity, and equality elevated my work to new heights. I am especially grateful to Alice for providing me with consistent and high-quality feedback on my writing and for always engaging seriously with my work and its weaknesses. Aside from my committee, I am deeply indebted to my spouse, who not only put up with my ridiculous schedule as I wrote this dissertation ("Did you know that Starbucks opens at 5am?"), but also is directly responsible for my entry into esports. Even as a lifelong gamer, I was too nervous to enter the Smash scene myself until he inspired me with his own high-level play and his awareness of emotion's role in expert performance. His patience while introducing me to this world, and the kindness of many other Chicagoland Smash community members, also demonstrated to me how an inclusive gaming community can elevate and support its members. I would like to thank several research assistants whose work directly impacted my ability to finish this dissertation and whose company kept me motivated, including Jon, Sabren, and Miriam. I wish you each success in your endeavors. I'm also grateful to the participants in my research, some of whom gave several hours and several days' worth of cortisol samples to further our scientific understanding of esports skill. (Don't worry, that paper is in the works too,
Developmental Science, 2016
Generic statements about the abilities of children's social groups (e.g. 'Girls/Boys are good at ... more Generic statements about the abilities of children's social groups (e.g. 'Girls/Boys are good at this game') negatively impact children's performanceeven if the statements are favorable towards children's own social groups. We explored the mechanism by which generic language impairs children's performance. Across three studies, our findings suggest that generic statements influence children's performance by creating an entity belief (i.e. a belief that a fixed ability determines performance). Children who were exposed to a generic statement about their social group's ability performed worse than children in control conditions. This effect hurt children's performance even when the person who made the generic statement was no longer present and a new person not privy to the statement replaced them. However, when children heard a generic statement paired with an effort explanation (i.e. 'Girls/Boys are good at this game because they try really hard when they draw') they performed better than children who heard the generic statement with no explanation (i.e. just 'Girls/Boys are good at this game') and children who heard the generic statement paired with a trait explanation (i.e. 'Girls/Boys are good at this game because they are smart and really good at drawing'). This work uncovers when and how generic statements that refer to the ability of one's social group hinder performance, informing the development of practices to improve student motivation and learning. Research highlights • Generic statements about the ability of one's social group hinder children's performance on a novel task. • Generic statements hinder performance by creating an entity belief. • Generic statements hinder children's performance even in the absence of the person who made the statement. • Generic statements lead children to adopt a performance goal (i.e. choosing an easier task) on a subsequent task. • Generic statements coupled with an effort explanation mitigate the negative effects of generic statements on children's performance.
Child development, Jan 20, 2018
This meta-analysis, spanning 5 decades of Draw-A-Scientist studies, examined U.S. children's ... more This meta-analysis, spanning 5 decades of Draw-A-Scientist studies, examined U.S. children's gender-science stereotypes linking science with men. These stereotypes should have weakened over time because women's representation in science has risen substantially in the United States, and mass media increasingly depict female scientists. Based on 78 studies (N = 20,860; grades K-12), children's drawings of scientists depicted female scientists more often in later decades, but less often among older children. Children's depictions of scientists therefore have become more gender diverse over time, but children still associate science with men as they grow older. These results may reflect that children observe more male than female scientists in their environments, even though women's representation in science has increased over time.
Journal of clinical oncology, Jun 1, 2024
The Journal of urology/The journal of urology, May 1, 2024
Journal of patient-reported outcomes, Mar 21, 2024
Applied Clinical Informatics, Dec 27, 2023
► clinical informatics ► electronic health records ► IT design and development methodologies ► pa... more ► clinical informatics ► electronic health records ► IT design and development methodologies ► patient-reported outcome measures ► health informatics interoperability
Competitive video gaming or esports is a field with the potential for gender-equal competition. H... more Competitive video gaming or esports is a field with the potential for gender-equal competition. However, esports is dominated by cisgender men at both the casual and professional levels. When a field is highly gender-imbalanced, gender minority groups tend to perceive the field as unwelcoming, which reduces interest in the field and further perpetuates unequal participation. One potential pathway to encourage interest and participation is the creation of gender-specific spaces, such as women-only tournaments in esports. To study the group effects of gender on tournament experience, we recruited cisgender women who were novice gamers for in-laboratory, one-on-one esports tournaments under two conditions: in women-only tournaments or mixedgender tournaments with equally novice cisgender men. Our results show that in matches between men and women, women underperformed against men regardless of whether her opponent had played more often, less often, or equal to her in the past year. In addition, women who played in women-only tournaments gave more accurate estimates of their skill and reported greater task importance than women who played in mixed-gender tournaments. In practice, women-only tournaments may aid recruitment and retention of women in esports as a supplement to gameplay in mixed-gender competitive spaces.
The Journal of Urology, Apr 1, 2023
Nature Reviews Urology, Mar 16, 2023
S37 nosed patients, how disease and treatment(s) impact patients' lives, and assess content valid... more S37 nosed patients, how disease and treatment(s) impact patients' lives, and assess content validity of PRO instruments (EORTC QLQ-OG25; EORTC QLQ-C30). MethodS: The most frequently experienced symptoms or impacts of advanced/metastatic GA/GEJ, and their degree of disturbance, were identified in qualitative interviews with recently diagnosed patients. Disturbance by symptoms or impacts was rated on a scale of 0 (not at all) to 10 (extremely). Frequency of prompted vs. unprompted responses and mean disturbance ratings were tabulated. Patients were asked cognitive interview questions to assess their comprehension of the QLQ-OG25 and QLQ-C30. ReSultS: Nine patients (n= 3 GA; n= 6 GEJ), on or off treatment, were interviewed. The majority of patients reported multiple disease-specific symptoms with moderate mean disturbance, including difficulty eating (89%; disturbance= 6.5), difficulty swallowing (78%; disturbance= 6.4), and abdominal pain (78%; disturbance= 7.4). Weakness (100%; disturbance= 5.4), anxiety (89%; disturbance= 5.9), inability to work (67%; dis-turbance= 7.5), and interference with daily activities (67%; disturbance= 7.0) were also reported. Additional symptom burden experienced by patients (e.g., loss of appetite, nausea, fatigue) was attributed to previous or ongoing treatments, particularly chemotherapy. Patients indicated the majority of items in the QLQ-OG25 and QLQ-C30 were easily understood and relevant to their experience with GA/GEJ. PRO instrument length was not a concern; patients thought completing these questionnaires, or instruments of similar length, would be easily done with important information collected. ConCluSionS: Patients with recently diagnosed advanced/metastatic GA/GEJ reported a variety of symptoms and impacts attributed to their underlying disease and/or treatments. The most important and relevant symptoms and impacts identified in the interviews can be assessed by the QLQ-OG25 and QLQ-C30. Our data provide evidence that PRO instruments are appropriate to measure symptoms and impacts in this population.
Future Oncology, Dec 1, 2022
Advanced renal cell carcinoma (RCC) remains a challenging oncologic disease to treat despite adva... more Advanced renal cell carcinoma (RCC) remains a challenging oncologic disease to treat despite advancements in therapeutics. Nonetheless, the development of tyrosine kinase inhibitors (TKIs) and immunotherapy has drastically altered the treatment landscape for advanced RCC over the past decade. The current standard-of-care treatment for advanced RCC involves combination TKI and immunotherapy regimens including cabozantinib and nivolumab as studied in the CheckMate 9ER trial. This review summarizes the preclinical and clinical evidence that led to the CheckMate 9ER study, as well as pertinent study aspects such as treatment efficacy, adverse events and patient-related outcomes.
Child Development, Mar 20, 2018
This meta-analysis, spanning 5 decades of Draw-A-Scientist studies, examined U.S. children's gend... more This meta-analysis, spanning 5 decades of Draw-A-Scientist studies, examined U.S. children's gender-science stereotypes linking science with men. These stereotypes should have weakened over time because women's representation in science has risen substantially in the United States, and mass media increasingly depict female scientists. Based on 78 studies (N = 20,860; grades K-12), children's drawings of scientists depicted female scientists more often in later decades, but less often among older children. Children's depictions of scientists therefore have become more gender diverse over time, but children still associate science with men as they grow older. These results may reflect that children observe more male than female scientists in their environments, even though women's representation in science has increased over time.
Journal of Electronic Gaming and Esports
Competitive video gaming or esports is a field with the potential for gender-equal competition. H... more Competitive video gaming or esports is a field with the potential for gender-equal competition. However, esports is dominated by cisgender men at both the casual and professional levels. When a field is highly gender-imbalanced, gender minority groups tend to perceive the field as unwelcoming, which reduces interest in the field and further perpetuates unequal participation. One potential pathway to encourage interest and participation is the creation of gender-specific spaces, such as women-only tournaments in esports. To study the group effects of gender on tournament experience, we recruited cisgender women who were novice gamers for in-laboratory, one-on-one esports tournaments under two conditions: in women-only tournaments or mixed-gender tournaments with equally novice cisgender men. Our results show that in matches between men and women, women underperformed against men regardless of whether her opponent had played more often, less often, or equal to her in the past year. In...
Future Oncology
Advanced renal cell carcinoma (RCC) remains a challenging oncologic disease to treat despite adva... more Advanced renal cell carcinoma (RCC) remains a challenging oncologic disease to treat despite advancements in therapeutics. Nonetheless, the development of tyrosine kinase inhibitors (TKIs) and immunotherapy has drastically altered the treatment landscape for advanced RCC over the past decade. The current standard-of-care treatment for advanced RCC involves combination TKI and immunotherapy regimens including cabozantinib and nivolumab as studied in the CheckMate 9ER trial. This review summarizes the preclinical and clinical evidence that led to the CheckMate 9ER study, as well as pertinent study aspects such as treatment efficacy, adverse events and patient-related outcomes.
Self-ratings of pre-match arousal predict tournament performance in real-world Super Smash Bros M... more Self-ratings of pre-match arousal predict tournament performance in real-world Super Smash Bros Melee players. Much of this effect is driven by justified expectation of loss, but even then general pre-match arousal exerts a negative, marginal effect on performance.
Although each of you specializes in fields that are distinct from gender and gaming, you've never... more Although each of you specializes in fields that are distinct from gender and gaming, you've nevertheless provided me with infinite guidance, scientific wisdom, and support both structural and emotional. Without your patience and flexibility, I would never have been able to explore the issues at the center of this dissertation. I'm also extremely grateful to my committee members Alice Eagly and Wendi Gardner, whose expertise in issues of gender, identity, and equality elevated my work to new heights. I am especially grateful to Alice for providing me with consistent and high-quality feedback on my writing and for always engaging seriously with my work and its weaknesses. Aside from my committee, I am deeply indebted to my spouse, who not only put up with my ridiculous schedule as I wrote this dissertation ("Did you know that Starbucks opens at 5am?"), but also is directly responsible for my entry into esports. Even as a lifelong gamer, I was too nervous to enter the Smash scene myself until he inspired me with his own high-level play and his awareness of emotion's role in expert performance. His patience while introducing me to this world, and the kindness of many other Chicagoland Smash community members, also demonstrated to me how an inclusive gaming community can elevate and support its members. I would like to thank several research assistants whose work directly impacted my ability to finish this dissertation and whose company kept me motivated, including Jon, Sabren, and Miriam. I wish you each success in your endeavors. I'm also grateful to the participants in my research, some of whom gave several hours and several days' worth of cortisol samples to further our scientific understanding of esports skill. (Don't worry, that paper is in the works too,
Developmental Science, 2016
Generic statements about the abilities of children's social groups (e.g. 'Girls/Boys are good at ... more Generic statements about the abilities of children's social groups (e.g. 'Girls/Boys are good at this game') negatively impact children's performanceeven if the statements are favorable towards children's own social groups. We explored the mechanism by which generic language impairs children's performance. Across three studies, our findings suggest that generic statements influence children's performance by creating an entity belief (i.e. a belief that a fixed ability determines performance). Children who were exposed to a generic statement about their social group's ability performed worse than children in control conditions. This effect hurt children's performance even when the person who made the generic statement was no longer present and a new person not privy to the statement replaced them. However, when children heard a generic statement paired with an effort explanation (i.e. 'Girls/Boys are good at this game because they try really hard when they draw') they performed better than children who heard the generic statement with no explanation (i.e. just 'Girls/Boys are good at this game') and children who heard the generic statement paired with a trait explanation (i.e. 'Girls/Boys are good at this game because they are smart and really good at drawing'). This work uncovers when and how generic statements that refer to the ability of one's social group hinder performance, informing the development of practices to improve student motivation and learning. Research highlights • Generic statements about the ability of one's social group hinder children's performance on a novel task. • Generic statements hinder performance by creating an entity belief. • Generic statements hinder children's performance even in the absence of the person who made the statement. • Generic statements lead children to adopt a performance goal (i.e. choosing an easier task) on a subsequent task. • Generic statements coupled with an effort explanation mitigate the negative effects of generic statements on children's performance.
Child development, Jan 20, 2018
This meta-analysis, spanning 5 decades of Draw-A-Scientist studies, examined U.S. children's ... more This meta-analysis, spanning 5 decades of Draw-A-Scientist studies, examined U.S. children's gender-science stereotypes linking science with men. These stereotypes should have weakened over time because women's representation in science has risen substantially in the United States, and mass media increasingly depict female scientists. Based on 78 studies (N = 20,860; grades K-12), children's drawings of scientists depicted female scientists more often in later decades, but less often among older children. Children's depictions of scientists therefore have become more gender diverse over time, but children still associate science with men as they grow older. These results may reflect that children observe more male than female scientists in their environments, even though women's representation in science has increased over time.