Online Mendelian Inheritance in Man (OMIM) (original) (raw)

CLEFT CHIN

Alternative titles; symbols

CHIN DIMPLE

Facies

- Y-shaped fissure of chin
- Peculiarity of mandible

TEXT

▼ Description

A bony peculiarity underlies the Y-shaped fissure of the chin.

▼ Inheritance

Guenther (1939) found 9 cases in 5 generations, and von Meirowsky (1924) reported 25 cases in 4 generations. By casual observation, Gorlin (1982) noted it in 4 generations, and McKusick (1988) found it in 3 generations. McKusick (1992) stated that a publishing colleague of his who had this trait was in the third generation of affected males in his family. In general, females appear to be less conspicuously affected than males.

▼ See Also:

▼ REFERENCES

1. Gorlin, R. J.Personal Communication. Minneapolis, Minn. 1982.
2. Guenther, H.Anomalien und Anomaliekomplexe in der Gegend des ersten Schlundbogens. Z. Menschl. Vererb. Konstitutionsl. 23: 43-52, 1939.
3. Lebow, M. R., Sawin, P. B.Inheritance of human facial features: a pedigree study involving length of face, prominent ears and chin cleft. J. Hered. 32: 127-132, 1941.
4. McKusick, V. A.Personal Communication. Baltimore, Md. 1992.
5. McKusick, V. A.Personal Communication. Baltimore, Md. 1988.
6. von Meirowsky, (NI).Kleine Beitraege zur Vererbungswissenschaft. Arch. Rass. Ges. Biol. 16: 439-443, 1924.

Creation Date:

Victor A. McKusick : 6/4/1986

alopez : 3/18/2004
terry : 7/25/1994
mimadm : 6/25/1994
warfield : 4/7/1994
supermim : 3/16/1992
carol : 3/4/1992
carol : 2/28/1992